scholarly journals A REVIEW ON PHARMACOLOGICAL AND PHYTOCHEMICAL PROFILE OF KHATMI (ALTHAEA OFFICINALIS LINN.): AN IMPORTANT MUCILAGINOUS PLANT AND ITS UTILIZATION IN UNANI SYSTEM OF MEDICINE

2021 ◽  
Vol 12 (3) ◽  
pp. 63-72
Author(s):  
Mazhar Husain ◽  
M Zaigham ◽  
Hamiduddin . ◽  
Abdul Wadud ◽  
Mohd Akhtar Ali
Keyword(s):  
Chemical Constituents ◽  
Therapeutic Tool ◽  
Pharmacological Activities ◽  
Unani Medicine ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Inflammatory Conditions ◽  
Whole Plant ◽  
Mucous Membranes ◽  
Phytochemical Profile

Traditional medicines / drugs are helpful for management of life style disorders and chronic and acute diseases. Khatmi (Althea officinalis Linn.) is a one of the commonly used drugs that has potential for management of many diseases. The meaning of Khatmi (Marshmallow) is Kaseer-al-manafe (Multi actions) in Unani literature. Roots, flowers and seeds of Khatmi are used as a medicament. According to Unani texts the main actions of Khatmi are demulcent, expectorant, defragment, concoctive, astringent, detergent and repellent. It is also used as part of many traditional recipes. Analgesic, emollient, antitussive and diuretic activity are the most ethnobotanical and traditional medicine considerations; also used in Unani medicine for the treatment of the different inflammatory conditions e.g., metritis (Warme reham), enteritis (Warme amaa), mastitis (Warme pistan), arthritis (Waja ul mafasil) etc. Alkaloids, terpenoids, tannins, Flavonoids, Polysaccharides, Phytosterols, Fatty acids, Mucilages, Hydroxybenzoic acid etc. are its main Chemical constituents. The whole plant parts yields mucilage in decoction and infusions, which is very useful in case of several ailments of mucous membranes. The scientifically proven / reported pharmacological activities are antitussive, antimicrobial, immunomodulatory, UV exposure protective, anti-inflammatory, immune stimulating, antioxidant, antifungal, hepatoprotective, ulcer protective etc. These all findings reveal immense utility of Khatmi and scope for developing as a potent therapeutic tool particularly in contemporary lifestyle and also in immune susceptible diseases which is an emerging concern.

scholarly journals Cocculus hirsutus (L.) W.Theob. (Menispermaceae): A Review on Traditional Uses, Phytochemistry and Pharmacological Activities

Medicines ◽  
2020 ◽  
Vol 7 (11) ◽  
pp. 69
Author(s):  
Rajan Logesh ◽  
Niranjan Das ◽  
Anjana Adhikari-Devkota ◽  
Hari Prasad Devkota
Keyword(s):  
Skin Diseases ◽  
Chemical Constituents ◽  
Scientific Information ◽  
Bibliographic Databases ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Traditional Uses

Background:Cocculus hirsutus (L.) W.Theob. (Menispermaceae) is a perennial climber distributed mostly in tropical and subtropical areas. The main aim of this article is to collect and analyze the scientific information related to traditional uses, bioactive chemical constituents and pharmacological activities. Methods: Scientific information on C. hirsutus was retrieved from the online bibliographic databases (e.g. MEDLINE/PubMed, SciFinder, Web of Science, Google Scholar and Scopus). Information regarding traditional uses was also acquired from secondary resources including books and proceedings. Results: Different plant parts of C. hirsutus were reported to be used for the treatment of fever, skin diseases, stomach disorders and urinary diseases. Alkaloids such as jasminitine, hirsutine, cohirsitine and their derivatives along with a few flavonoids, triterpene derivatives and volatile compounds were reported from whole plant or different plant parts. Extracts were evaluated for their antimicrobial, antidiabetic, immunomodulatory and hepatoprotective activities among others. Conclusion: Although widely used in traditional medicines, only a few studies have been performed related to chemical constituents. Most of the biological activity evaluations were carried out using in vitro evaluation methods and only a few studies were carried out in animal models. In the future, properly designed in vivo and clinical studies are necessary to evaluate the pharmacological activities of C. hirsutus along with bioassay-guided studies to isolate and identify the active constituents.

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

scholarly journals Ethnomedical uses, chemical constituents, and evidence-based pharmacological properties of Chenopodium ambrosioides L.: extensive overview

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Félicien Mushagalusa Kasali ◽  
Jonans Tusiimire ◽  
Justin Ntokamunda Kadima ◽  
Amon Ganafa Agaba
Keyword(s):  
Large Scale ◽  
Chemical Constituents ◽  
Main Body ◽  
Pharmacological Properties ◽  
Chenopodium Ambrosioides ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Chemical Studies ◽  
Ethnomedicinal Uses ◽  
Significant Health

Abstract Background The Chenopodium genus is a plant family widely spread worldwide that includes various plant species reputed to possess several medicinal virtues in folk medicines. Chenopodium ambrosioides L. is among the most used plants in traditional medicines worldwide. This review aimed to highlight ethnomedicinal uses, phytochemical status, and pharmacological properties of C. ambrosioides L. Main body of the abstract The analysis of relevant data highlights various ethnomedicinal uses against human and veterinary diseases in forty countries. Most indications consisted of gastrointestinal tract dysfunctioning troubles and worms parasitemia. Around 330 chemical compounds have been identified in different plant parts, especially in its essential oil fractions (59.84%). However, only a few compounds—mainly monoterpenes and glycosides—have been isolated and characterized. Experimental pharmacological studies validated a large scale of significant health benefits. It appeared that many monoterpenes are antioxidant, insecticidal, trypanocidal, analgesic, antifungal, anti-inflammatory, anti-arthritic, acaricidal, amoebicidal, anthelmintic, anticancer, antibacterial, antidiabetic, antidiarrheal, antifertility, antifungal, anti-leishmanial, antimalarial, antipyretic, antisickling, antischistosomal, antiulcer, anxiolytic, immunomodulatory, molluscicidal, and vasorelaxant agents. Short conclusion Thus, the Chenopodium ambrosioides species necessitates further chemical studies to isolate and characterize new bioactive secondary metabolites and pharmacological investigations to precise the mechanisms of action before clinical trials.

scholarly journals Phytochemical Profile and Biological Activity ofNelumbo nucifera

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Keshav Raj Paudel ◽  
Nisha Panth
Keyword(s):  
Traditional Medicine ◽  
Nutritional Value ◽  
Functional Foods ◽  
Skin Diseases ◽  
Chemical Constituents ◽  
Bioactive Constituents ◽  
Tissue Inflammation ◽  
Whole Plant ◽  
Phytochemical Profile ◽  
Different Parts

Nelumbo nuciferaGaertn. (Nymphaeaceae) is a potential aquatic crop grown and consumed throughout Asia. All parts ofN. nuciferahave been used for various medicinal purposes in various systems of medicine including folk medicines, Ayurveda, Chinese traditional medicine, and oriental medicine. Many chemical constituents have been isolated till the date. However, the bioactive constituents of lotus are mainly alkaloids and flavonoids. Traditionally, the whole plant of lotus was used as astringent, emollient, and diuretic. It was used in the treatment of diarrhea, tissue inflammation, and homeostasis. The rhizome extract was used as antidiabetic and anti-inflammatory properties due to the presence of asteroidal triterpenoid. Leaves were used as an effective drug for hematemesis, epistaxis, hemoptysis, hematuria, and metrorrhagia. Flowers were used to treat diarrhea, cholera, fever, and hyperdipsia. In traditional medicine practice, seeds are used in the treatment of tissue inflammation, cancer and skin diseases, leprosy, and poison antidote. Embryo of lotus seeds is used in traditional Chinese medicine as Lian Zi Xin, which primarily helps to overcome nervous disorders, insomnia, and cardiovascular diseases (hypertension and arrhythmia). Nutritional value of lotus is as important as pharmaceutical value. These days’ different parts of lotus have been consumed as functional foods. Thus, lotus can be regarded as a potential nutraceutical source.

scholarly journals Traditional Uses, Phytochemistry, and Pharmacology of Elegia Species: A Review

2021 ◽  
Vol 90 (1) ◽  
pp. 4
Author(s):  
Panagiotis Lymperis ◽  
Ekaterina-Michaela Tomou ◽  
Marco Nuno De Canha ◽  
Namrita Lall ◽  
Helen Skaltsa
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Comprehensive Search ◽  
Extensive Information ◽  
The Subject ◽  
Phytochemical Profile ◽  
Ecological Dominance ◽  
New Research

In South Africa, plants belonging to the Restionaceae family possess an ecological dominance. As a result, they have been the subject of numerous morphological, anatomical, and evolutionary studies. However, few studies have focused on their phytochemical profile and their potential pharmacological activities. The genus Elegia L. is the second largest of this family comprising 52 species, which are mainly used as materials for thatching. Limited studies on the chemical constituents of Elegia species and their importance as medicinal plants have been undertaken. This review provides constructive and extensive information about the botanical characterization, distribution, traditional uses, phytochemistry and pharmacology of the genus Elegia. A comprehensive search of previously published literature was performed for studies on this genus, using databases with different key search words. This survey documented 52 Elegia species summarizing their previous taxonomic classification. In addition, 14 species were found to be studied for their phytochemical profile, revealing 14 chemical compounds. Concerning their biological activities, only one species (E. tectorum (L.f.) Moline and H.P.Linder) is reported for its anti-wrinkle activity. Moreover, two species are locally used for thatching and as materials for brooms. The present review highlights the Elegia genus as an important source of bioactive phytochemicals with flavonol glycosides being the main metabolites and reveals the uncharted territory of this genus for new research studies.

scholarly journals Morphology, Phytochemistry and Pharmacological Activity of Vitex negundo: An Overview

2020 ◽  
Vol 10 (3-s) ◽  
pp. 280-285
Author(s):  
Yogendra Singh ◽  
Pankaj Mishra ◽  
Pushpendra Kannojia
Keyword(s):  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
Plant Morphology ◽  
Antitubercular Activity ◽  
Depth Information ◽  
World Population ◽  
Vitex Negundo ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines

Now days a herbal and traditional medicines mostly used in all over the world according to WHO, about 60 to 65% world population practicing herbal and traditional medicines. Vitex negundo Linn. is an aromatic herb belong to family Verbenaceae. It is also known as Nirgundi, Five leaved chaste tree. Plants have many chemical constituents as flavonoids, volatile oil, triterpenes, diterpenes, sesquiterpenes, lignan, flavones, glycosides, iridoid glycosides and stilbene derivative. These chemical constituents are present in each part of the plant. Vitex negundo extract have various pharmacological activities such as anti-inflammatory, antipyretic, anti-arthritic, antioxidant, analgesic activity, antibacterial activity, antitumor activity, anti-amnesic activity, anxiolytic activity, Nephroprotective activity, anti-HIV activity, Antitubercular activity, antieosinophilic activity, anti-snake venom activity. This review article provides depth information related to plant morphology, cultivation, chemical constitutes, pharmacological activities and their medicinal uses. Keywords: Vitex negundo, Nirgundi, Casticin, Anti-Gout Activity

scholarly journals Pharmacognostic and Pharmacological Study of Helicteres isora. Linn. - A Review

2021 ◽  
pp. 208-214
Author(s):  
Swapnali S. Mankar ◽  
Muh. Younas ◽  
Awadhut Pimpale ◽  
Devyani Awari
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Study ◽  
Bark Extract ◽  
Root Extract ◽  
Medical Sciences ◽  
Plant Parts ◽  
Whole Plant ◽  
Helicteres Isora ◽  
Antihyperlipidemic Activity ◽  
Fruit Powder

Aim: In this article we compiled the whole plant of Helicteres.isora Linn showed excellent medicinal merits from ancient time belonging to the family Sterculiacea, which commonly known as murud sheng. Study Design: The Pharmacognostic study i.e. microscopic and macroscopic study with preliminary phytochemical test on different parts of plant performed in a Datta Meghe college of pharmacy,Datta meghe Institute of Medical sciences, Wardha, in collaboration with Balkh university,Mazar-e-Sharif during the period of January 2021 to Septmber 2021. Methodology: In the preliminary study focus on all pharmacognostic, by microscopic identification,by TLC, HPTLC by fingerprint application and phytochemical test of root extract, stem, leaf and fruit powder from different researchers study,  which showed the presence of carbohydrates, protein, alkaloids, cardiac glycoside, flavonoids, tannins, essential oil etc which shows number of medicinal merits Results: During the study all investigators investigate, different region shows minute change in organoleptic charecteristics as well as phytochemical constituents and pharmacological study exhibits activities like Fruit showed Antioxidant, Antidiabetic and Antihyperlipidemic activity, Bark extract showed Antihelmintic activity  , Root extract as  Anticancer. Conclusion: According to study we conclude that  Helicteres Isora Linn whole plant parts as well chemical constituents in every part is effective and used medicinally so further investigations are necessary to find out the active bio active molecules responsible to cure different disorders

scholarly journals Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 872 ◽  
Author(s):  
Gaber El-Saber Batiha ◽  
Amany Magdy Beshbishy ◽  
Lamiaa G. Wasef ◽  
Yaser H. A. Elewa ◽  
Ahmed A. Al-Sagan ◽  
...  
Keyword(s):  
Allium Sativum ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Biological Properties ◽  
Herbaceous Plant ◽  
Anticancer Activities ◽  
Active Constituent ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Traditional Remedy

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities including antibacterial, antiviral, antifungal, antiprotozoal, antioxidant, anti-inflammatory, and anticancer activities among others. This review examines the phytochemical composition, pharmacokinetics, and pharmacological activities of A. sativum extracts as well as its main active constituent, allicin.

Chemical Constituents and Pharmacological Activities of Family Flacourtiaceae: A Class of Important Phytomedicine

2020 ◽  
Vol 48 (02) ◽  
pp. 287-328
Author(s):  
Yu Zhang ◽  
Jing Kong ◽  
Jin-Hua Zhang ◽  
Lu Wang ◽  
Wei Zhang ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Chemical Constituents ◽  
Chemical Diversity ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Pharmacological Studies ◽  
Phytochemical Studies ◽  
Further Development

Flacourtiaceae plants are widely used as folk medicines in traditional medicine systems for its chemical diversity and pharmacological activities. In many different areas, Flacourtiaceae plants are used as traditional medicines for the treatment of ulcers, malaria, rheumatism. The Flacourtiaceae plants contain a very plentiful chemical composition, and phytochemical studies show that the Flacourtiaceae plants contained terpenoids, aromatic glycosides, flavnoids, phenylpropanoids, alkaloids, fatty hydrocarbon, and other compounds. In pharmacological studies, various extract and isolated individual compounds exhibited antitumor, anti-oxidation, and anti-inflammatory activities. In this review, the literature data on the chemical constituents and pharmacological investigations of the Flacourtiaceae plants are summarized, to provide information about a more comprehensive chemical composition and detailed pharmacological activities of Flacourtiaceae plants, with a view of further development of clinical medication. However, research on quantitative analysis, toxicity, and drug safety in vitro and in vivo is still insufficient, and further research is required.

scholarly journals Appraisals of Bangladeshi Medicinal Plants Used by Folk Medicine Practitioners in the Prevention and Management of Malignant Neoplastic Diseases

2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Md. Nur Kabidul Azam ◽  
Md. Mizanur Rahman ◽  
Samanta Biswas ◽  
Md. Nasir Ahmed
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
Folk Medicine ◽  
Cell Types ◽  
The Body ◽  
Plant Leaves ◽  
Neoplastic Diseases ◽  
Plant Parts ◽  
National Herbarium ◽  
Whole Plant

Cancer is a group of diseases which is categorized to differentiate into diverse cell types and move around in the body to sites of organogenesis that is key to the process of tumor genesis. All types of cancer fall into the group of malignant neoplastic diseases. In Bangladesh, cancer is now one of the foremost killer diseases and its personal, social, and economic bearing are huge. Plant-derived natural compounds (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan, and irinotecan) are useful for the treatment of cancer. Since there is no extensive ethnobotanical research study in Bangladesh regarding the traditional uses of medicinal plants against neoplasms, therefore, a randomized ethnopharmacological surveys were carried out in 3 districts of Bangladesh to learn more about the usage of anticancer medicinal plants and their chemical constituents having antineoplastic activity. Comprehensive interviews were conducted to the folk medicine practitioners and medicinal plants as pointed out by them were photographed, collected, deposited, and identified at the Bangladesh National Herbarium. The various plant parts have been used by the healers which included whole plant, leaves, fruits, barks, roots, and seeds. This study evaluated considerable potential for discovery of novel compounds with less side effects in the management and prevention of malignancy in cancer.

Sign in / Sign up

Export Citation Format

Share Document