Role of different imaging modalities in the evaluation of normal and diseased thymus

Abstract The goal of glioma surgery is maximal safe resection in order to provide optimal tumor control and survival benefit to the patient. There are multiple imaging modalities beyond traditional contrast-enhanced magnetic resonance imaging (MRI) that have been incorporated into the preoperative workup of patients presenting with gliomas. The aim of these imaging modalities is to identify cortical and subcortical areas of eloquence, and their relationship to the lesion. In this article, multiple modalities are described with an emphasis on the underlying technology, clinical utilization, advantages, and disadvantages of each. functional MRI and its role in identifying hemispheric dominance and areas of language and motor are discussed. The nuances of magnetoencephalography and transcranial magnetic stimulation in localization of eloquent cortex are examined, as well as the role of diffusion tensor imaging in defining normal white matter tracts in glioma surgery. Lastly, we highlight the role of stimulated Raman spectroscopy in intraoperative histopathological diagnosis of tissue to guide tumor resection. Tumors may shift the normal arrangement of functional anatomy in the brain; thus, utilization of multiple modalities may be helpful in operative planning and patient counseling for successful surgery.

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Not All That Shines on a PET Scan Is Cancer: A Silicone-Induced Granuloma Masquerading as Malignancy

Clinics and Practice ◽

10.3390/clinpract11010003 ◽

2020 ◽

Vol 11 (1) ◽

pp. 8-12

Author(s):

Krishna Vedala ◽

Philip Sobash ◽

Deborah Johnson ◽

Krishna Kakkera

Keyword(s):

Pet Scan ◽

Imaging Modalities ◽

Ct Scans ◽

Pet Ct ◽

Suspicious Lesions

PET/CT scans are frequently used in the initial workup of suspicious lesions but not all that lights up on a PET is cancerous. We wish to discuss a case of silicone-induced granuloma mimicking malignancy and the role of other imaging modalities for further workup.

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Role of Imaging in Diagnosis and Management of COVID-19: A Multiorgan Multimodality Imaging Review

Frontiers in Medicine ◽

10.3389/fmed.2021.765975 ◽

2021 ◽

Vol 8 ◽

Author(s):

Vinithra Varadarajan ◽

Mahsima Shabani ◽

Bharath Ambale Venkatesh ◽

Joao A. C. Lima

Keyword(s):

Multimodality Imaging ◽

Imaging Techniques ◽

Standard Of Care ◽

Review Article ◽

Health Centers ◽

Imaging Modalities ◽

Imaging Protocol ◽

Diagnosis And Management ◽

Radiologic Findings

In this pandemic of Coronavirus disease 2019 (COVID-19), a vast proportion of healthcare resources, including imaging tools, have been dedicated to the management of affected patients; yet, the frequent reports of unknown presentations and complications of disease over time have been changing the usual standard of care and resource allocation in health centers. As of now, we have witnessed multisystemic symptoms requiring the collaboration of different clinical teams in COVID-19 patients' care. Compared to previous viral pandemics, imaging modalities are now playing an essential role in the diagnosis and management of patients. This widespread utility of imaging modalities calls for a deeper understanding of potential radiologic findings in this disease and identifying the most compatible imaging protocol with safety precautions. Although initially used for respiratory tract evaluation, imaging modalities have also been used for cardiovascular, neurologic, and gastrointestinal evaluation of patients with COVID-19. In this narrative review article, we provide multimodality and multisystemic review of imaging techniques and features that can aid in the diagnosis and management of COVID-19 patients.

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Role of99mTc-ECD SPECT in the Management of Children with Craniosynostosis

BioMed Research International ◽

10.1155/2014/172646 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Mayadhar Barik ◽

Minu Bajpai ◽

Rashmi Ranajn Das ◽

Arun Malhotra ◽

Shasanka Shekhar Panda ◽

...

Keyword(s):

Perfusion Defect ◽

Cerebral Hemisphere ◽

Clinical Findings ◽

Regional Perfusion ◽

Imaging Modalities ◽

Early Surgery ◽

Mental Performance ◽

Perfusion Defects ◽

The Mean

Purpose of the Report. There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role ofTc99m-ECD SPECT in a large number of subjects with craniosynostosis.Materials and Methods. We prospectively analyzed a cohort of 85 patients with craniosynostosis from year 2007 to 2012. All patients underwent evaluation withTc99m-ECD SPECT and the results were correlated with radiological and surgical findings.Results.Tc99m-ECD SPECT revealed regional perfusion abnormalities in the cerebral hemisphere corresponding to the fused sutures preoperatively that disappeared postoperatively in all the cases. Corresponding to this, the mean mental performance quotient (MPQ) increased significantlyP<0.05postoperatively only in those children with absent perfusion defect postoperatively.Conclusions. Our study suggests that early surgery and release of craniosynostosis in patients with preoperative perfusion defects (absent onTc99m-ECD SPECT study) are beneficial, as theylead to improved MPQ after surgery.

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