scholarly journals Learner-Centered Inquiry in Undergraduate Biology: Positive Relationships with Long-Term Student Achievement

2010 ◽  
Vol 9 (4) ◽  
pp. 462-472 ◽  
Author(s):  
Terry L. Derting ◽  
Diane Ebert-May
Keyword(s):  
Learning Experience ◽  
Collaborative Work ◽  
Introductory Courses ◽  
Traditional Lecture ◽  
Undergraduate Biology ◽  
Learner Centered ◽  
Short And Long Term ◽  
High Level ◽  
Biology Curriculum

We determined short- and long-term correlates of a revised introductory biology curriculum on understanding of biology as a process of inquiry and learning of content. In the original curriculum students completed two traditional lecture-based introductory courses. In the revised curriculum students completed two new learner-centered, inquiry-based courses. The new courses differed significantly from those of the original curriculum through emphases on critical thinking, collaborative work, and/or inquiry-based activities. Assessments were administered to compare student understanding of the process of biological science and content knowledge in the two curricula. More seniors who completed the revised curriculum had high-level profiles on the Views About Science Survey for Biology compared with seniors who completed the original curriculum. Also as seniors, students who completed the revised curriculum scored higher on the standardized Biology Field Test. Our results showed that an intense inquiry-based learner-centered learning experience early in the biology curriculum was associated with long-term improvements in learning. We propose that students learned to learn science in the new courses which, in turn, influenced their learning in subsequent courses. Studies that determine causal effects of learner-centered inquiry-based approaches, rather than correlative relationships, are needed to test our proposed explanation.

Which Way Is Better? Comparison of Two Interactive Modeling Approaches for Teaching Meiosis in an Introductory Undergraduate Biology Course

2019 ◽  
Vol 81 (2) ◽  
pp. 98-109
Author(s):  
Kelsey J. Metzger ◽  
Joanna Yang Yowler
Keyword(s):  
Student Perceptions ◽  
Learning Experience ◽  
Learning Approaches ◽  
Learning Gains ◽  
Free Response ◽  
Traditional Lecture ◽  
Undergraduate Biology ◽  
Modeling Approaches ◽  
Post Assessment ◽  
Mitosis And Meiosis

The processes of mitosis and meiosis are oft-cited and long-standing examples of concepts that are difficult for students to learn and understand. While there are many examples in the literature of “how-to-do-it,” innovative instructional approaches for teaching mitosis and meiosis, publications that include measurement of learning gains are fewer. Moreover, when measurement of learning gains are reported, the outcomes of innovative approaches are most often compared to outcomes from traditional lecture-format instruction. In contrast, this research compares two active-learning approaches to teaching meiosis through modeling in an introductory undergraduate biology course for health sciences majors. Items from the published, validated Meiosis Concept Inventory were used for pre- and post-instruction assessment. In addition, we collected data regarding student perceptions of the learning experience in each modeling scenario through two Likert-scale items and two free-response items. Overall, students demonstrated significant learning gains from pre- to post-assessment. We found no significant differences in performance on the posttest between the two modeling approaches, indicating that the selection of the modeling activity used to support student learning can be made on the basis of other criteria, such as instructor preference, physical classroom layout, or available supplies.

scholarly journals Evaluation of the Performance of a Warm Mix Asphalt (WMA) Considering Aged and Unaged Specimens

Coatings ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1241
Author(s):  
Giuseppe Piccone ◽  
Giuseppe Loprencipe ◽  
Arminda Almeida ◽  
Nicola Fiore
Keyword(s):  
Fatigue Behavior ◽  
Permanent Deformation ◽  
Road Construction ◽  
Warm Mix Asphalt ◽  
Environmental Aspects ◽  
Bituminous Mixtures ◽  
Water Sensitivity ◽  
Short And Long Term ◽  
High Level

In the last decades, all technology production sectors reached a high level of development, without neglecting the attention to environmental aspects and safeguarding energy resources. Moreover, in the sector of pavement industry, some alternatives of bituminous mixtures were proposed to reduce the greenhouse gas emissions. One of these is the warm mix asphalt (WMA), a mixture produced and compacted at lower temperatures compared to traditional hot mix asphalt (HMA) (about 40 °C less), to allow a reduction of emissions into the atmosphere and the costs. Other operative benefits concern the health of workers during the whole road construction process, the reduction of distances to which the mixture can be transported, and therefore also the positioning of the plants. However, it is not all benefits, since reduced production temperatures can bring short- and long-term water sensitivity issues, which could threaten the pavement performance. This paper evaluated the performance (water sensitivity, stiffness, fatigue, and permanent deformation) of a WMA produced using a warm mix fabrication bitumen and compared it with an HMA tested in parallel. In general, except for the resistance to permanent deformation, the WMA presented performances comparable to HMA. Regarding the fatigue behavior of asphalt mixtures, the WMA was less affected by ageing conditions, despite it showing lower performance than HMA.

Effective Physical Therapy Education Through Increased Student Engagement

2019 ◽  
pp. 154-183
Author(s):  
Rajiv A. Dalal
Keyword(s):  
Digital Learning ◽  
Physical Therapy Education ◽  
Traditional Lecture ◽  
Technology In Teaching ◽  
Learning Techniques ◽  
Short And Long Term ◽  
Content Coverage ◽  
Therapy Education

As technology grows, there are many applications into the educational arena. Educators are tasked with incorporating technology in teaching. This is best done through a systematic means to create effective change. The Digital Learning Initiative (DLI) was created with this in mind. This is a case study in the transformation of teaching methods through the DLI. The redesign was centered around the principles of assessment and course mapping. The course was reworked to allow for more feedback and interaction with the instructor. Digital apps were utilized to supplement content. Class sessions changed from traditional lecture into a flipped environment using active learning techniques. After the redesign, students improved in graded performance, as well as in engagement with the instructor and classmates. The instructor also reported increased engagement with students and more in-depth content coverage. Redesign is a dynamic process with some trial and error; however, with a solid framework based on assessment, there is potential for meaningful short and long-term course change.

scholarly journals Enhancing Interdisciplinary, Mathematics, and Physical Science in an Undergraduate Life Science Program through Physical Chemistry

2009 ◽  
Vol 8 (1) ◽  
pp. 15-28 ◽  
Author(s):  
David P. Pursell
Keyword(s):  
Physical Chemistry ◽  
Physical Science ◽  
Life Science ◽  
Student Outcome ◽  
Student Resistance ◽  
Undergraduate Biology ◽  
Chemistry Students ◽  
Outcome Goals ◽  
Biology Curriculum

BIO2010 advocates enhancing the interdisciplinary, mathematics, and physical science components of the undergraduate biology curriculum. The Department of Chemistry and Life Science at West Point responded by developing a required physical chemistry course tailored to the interests of life science majors. To overcome student resistance to physical chemistry, students were enabled as long-term stakeholders who would shape the syllabus by selecting life science topics of interest to them. The initial 2 yr of assessment indicates that students have a positive view of the course, feel they have succeeded in achieving course outcome goals, and that the course is relevant to their professional future. Instructor assessment of student outcome goal achievement via performance on exams and labs is comparable to that of students in traditional physical chemistry courses. Perhaps more noteworthy, both student and instructor assessment indicate positive trends from year 1 to year 2, presumably due to the student stakeholder effect.

scholarly journals Global Game Jam in Latin-America, a Collaborative Videogame Learning Experience

2020 ◽  
Vol 9 (3) ◽  
pp. 28
Author(s):  
Angel Torres-Toukoumidis ◽  
Juan Pablo Salgado Guerrero ◽  
Sheila Peñalva ◽  
Paola Carrera
Keyword(s):  
New Media ◽  
Video Game ◽  
Life Experience ◽  
Learning Experience ◽  
Collaborative Work ◽  
3D Design ◽  
Level Of Education ◽  
Global Game ◽  
Level Of Knowledge ◽  
High Level

Videogame production events, particularly the Global Game Jam (GGJ), is an activity par excellence aimed at the development of the world’s largest games, enhancing the form of personal expression, critical thinking, and appropriation of new media through collaborative work. The general objective is to explore the development process within the context of the GGJ, calculating the correlation between level of education and source of inspiration, the correlation between level of education and purpose of the game to be designed in the Global Game Jam and the correlation between level of education and skills. The main source of inspiration is defined by game genre, game mechanics, or other video game, in addition the purpose of the game is mainly due to learning a technical skill, enjoy doing it, and generate satisfaction in the players. Finally, the skills that prevail are 2D Design, Programming, and 3D Design. People with a high level of knowledge have the same passion as those who have just started in the multidisciplinary field of the development of video games motivated by creating an original game that has a good script and provides them a life experience.

scholarly journals The Magic of Project Resolution in a Short Period of Time: Design Sprint Applied in Higher Education

2021 ◽  
Vol 15 (2) ◽  
pp. 45
Author(s):  
Gastón Sanglier ◽  
Carmen B. Martínez Cepa ◽  
Inés Serrano Fernández ◽  
Aurora Hernández González ◽  
Juan Carlos Zuíl Escobar
Keyword(s):  
Higher Education ◽  
Time Management ◽  
New Technologies ◽  
Learning Experience ◽  
Collaborative Work ◽  
Social Strategies ◽  
Short Period ◽  
The One ◽  
High Level ◽  
Short Time

The research conducted in this study was applied to multidisciplinary groups of Higher Education belonging to different degrees using the methodology proposed by the Design Sprint (DS) tool for the achievement of different challenges/objectives in a very short time. The methodology used is an adaptation of the one proposed by the DS, carried out in five non-consecutive stages/sessions focused on students of the first two years of different degrees of the CEU San Pablo University. The students, in general, have valued very positively the collaborative work in small groups, the time management and the administration of work under stress. The abandonment of the different challenges was set at 32%. A high level of commitment has been appreciated among the students to reach the proposed challenges, however, the work of the mentors as guides, becomes essential in the first courses of the different degrees in a general way. The application of the SD methodology provides students with an increase in their performance, in their ability to work in teams and to adapt in the best possible way to the demands of a society that is increasingly demanding new technologies. Students have increased their ability to reflect, transform and innovate in the different objectives/challenges/projects demanded by the new circumstances and social strategies. The support of good mentors, critics and specialists in the different areas to be addressed is necessary to offer students a better learning experience.

AGM-Derived Endothelial Cells and Notch Ligands Provide Embryonic Hematopoietic Stem Cell-Supportive Niches In Vitro

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 1167-1167
Author(s):  
Brandon K Hadland ◽  
Barbara Varnum-Finney ◽  
Randall T Moon ◽  
Jason M Butler ◽  
Shahin Rafii ◽  
...  
Keyword(s):  
Stem Cells ◽  
Endothelial Cells ◽  
Hematopoietic Cells ◽  
Hematopoietic Stem ◽  
Small Molecule Inhibition ◽  
Short And Long Term ◽  
High Level ◽  
Notch Ligands

Abstract Greater knowledge of embryonic niche signals regulating the establishment, maintenance, and expansion of hematopoietic stem cells (HSC) during development will be essential in deriving therapeutically useful HSC from pluripotent stem cells (PSC). To this end, we have used the murine embryo model to dissect components of embryonic hematopoietic microenvironments which are sufficient to support nascent HSC and their precursors in vitro. We demonstrate that Akt pathway-activated endothelial cells (ECs) derived from the AGM (aorta-gonad-mesonephros) region, a critical site of HSC emergence during development, can substantially increase short and long-term multilineage engraftment potential from isolated embryonic day 11 (E11) VE-Cadherin+/CD45+ AGM-derived hematopoietic cells by co-culture in vitro. Furthermore, preliminary experiments show that co-culture with AGM-ECs also promotes high level, multilineage engraftment capacity from VE-cadherin+/c-kit+ precursors isolated from younger embryos (E9-E10). These results suggest that endothelial cells from an embryonic HSC-producing niche provide signals sufficient to promote maturation of HSC from embryonic precursors and subsequently support early HSC expansion in vitro. Further dissection of required signals for embryonic HSC expansion identified a unique combination of Notch activation by immobilized Notch ligands, cytokines, and small molecule inhibition of the TGF-β pathway, which is sufficient to inhibit differentiation and enhance self-renewal of embryonic, definitive-stage hematopoietic precursors in vitro. Notably, these conditions significantly increased short and long-term, multilineage repopulating HSC from E11 VE-Cadherin+/CD45+, but not E9-10 VE-Cadherin+/c-kit+ AGM-derived hematopoietic cells, indicating AGM-ECs provide additional, yet to be identified, signals for HSC maturation from developmental precursors. These findings have important implications for dissecting critical niche signals for HSC formation and expansion that will be essential for addressing the elusive goal of deriving HSC from pluripotent precursors. Disclosures: Rafii: Angiocrine Bioscience: Founder Other.

Corrected transposition of the great arteries and dextrocardia: a case of prenatal diagnosis of these rare anomalies and literature review

2018 ◽  
Author(s):  
I.V. Komarova
Keyword(s):  
Prenatal Diagnosis ◽  
Literature Review ◽  
Septal Defect ◽  
Prenatal Counseling ◽  
Prenatal Consultation ◽  
Short And Long Term ◽  
Long Term Prognosis ◽  
High Level ◽  
Corrected Transposition

The case of prenatal ultrasound diagnosis of combination corrected transposition of the great arteries (cTGA) with dextrocardia at 21 weeks of gestation is presented. The high-level ventricular septal defect and stenosis of pulmonary artery were associated cardiac pathologies. Another anomalies of the fetus were not detected. The fetus karyotype was normal, defined by classical cytogenetic analysis. The prenatal consultation assessed the prognosis for life and health as unfavorable. According to patient’s decision the pregnancy was terminated. Literature review of antenatal diagnostics of cTGA and combined cTGA with dextrocardia and the matters of short- and long-term prognosis for the fetus were presented in the paper. The issues of the difficulty of detecting cTGA in a fetus and prenatal counseling is discussed, especially in the presence of an abnormality of the intrathoracic location of the heart.

scholarly journals Molecular mechanisms involved in the adaptive regulation of the colonic thiamin pyrophosphate uptake process

2017 ◽  
Vol 313 (6) ◽  
pp. C655-C663 ◽  
Author(s):  
Kasin Yadunandam Anandam ◽  
Padmanabhan Srinivasan ◽  
Veedamali S. Subramanian ◽  
Hamid M. Said
Keyword(s):  
Promoter Activity ◽  
Molecular Mechanisms ◽  
Adaptive Regulation ◽  
Cell Homogenate ◽  
Short Term Exposure ◽  
Uptake Process ◽  
Short And Long Term ◽  
High Level ◽  
Thiamin Pyrophosphate

A considerable amount of the thiamin generated by gut microbiota exists in the form of thiamin pyrophosphate (TPP). We have previously shown that human colonocytes possess an efficient carrier-mediated uptake process for TPP that involves the SLC44A4 system and this uptake process is adaptively regulated by prevailing extracellular TPP level. Little is known about the molecular mechanisms that mediate this adaptive regulation. We addressed this issue using human-derived colonic epithelial NCM460 cells and mouse colonoids as models. Maintaining NCM460 cells in the presence of a high level of TPP (1 mM) for short (2 days)- and long-term (9 days) periods was found to lead to a significant reduction in [3H] TPP uptake compared with cells maintained in its absence. Short-term exposure showed no changes in level of expression of SLC44A4 protein in total cell homogenate (although there was a decreased expression in the membrane fraction), mRNA, and promoter activity. However, a significant reduction in the level of expression of the SLC44A4 protein, mRNA, and promoter activity was observed upon long-term maintenance with the substrate. Similar changes in Slc44a4 mRNA expression were observed when mouse colonoids were maintained with TPP for short- and long-term periods. Expression of the transcription factors ELF3 and CREB-1 (which drive the SLC44A4 promoter) following long-term exposure was unchanged, but their binding affinity to the promoter was decreased and specific histone modifications were also observed. These studies demonstrate that, depending on the period of exposure, different mechanisms are involved in the adaptive regulation of colonic TPP uptake by extracellular substrate level.

Numerical Modelling of the THM Behaviour of Underground Radioactive Waste Storages Cell

2011 ◽  
Vol 378-379 ◽  
pp. 187-190
Author(s):  
Xiu Mei Qiu ◽  
Han Bing Bian
Keyword(s):  
Radioactive Wastes ◽  
Storage Cell ◽  
Coupling Process ◽  
Mechanical Coupling ◽  
Quantitative Results ◽  
Short And Long Term ◽  
High Level ◽  
Storage Structures ◽  
Damage Processes

In this paper, a storage cell for the high level radioactive wastes is studied in order to identify and demonstrate the coupled phenomena evolving in the high level radioactive wastes (HLW) storage. According to the various important processes in the storage structures, special attention is paid on the coupling elastoplastic and viscoplastic damage processes in short and long term. In the calculations, the complicated thermo-hydro-mechanical coupling process has been taken into consideration. These numerical calculations allow us to obtain some quantitative results describing the mechanical behaviour and coupling thermo-hydro-mechanical processes for a short-and long-term in the storage cell.

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