Acute intoxication with doxazosin

2005 ◽  
Vol 24 (6) ◽  
pp. 337-339 ◽  
Author(s):  
Salim Satar ◽  
Ahmet Sebe ◽  
Akkan Avci ◽  
Hasan Yesilagac ◽  
Yuksel Gokel
Keyword(s):  
Emergency Department ◽  
Acute Intoxication ◽  
Supportive Treatment

Experience with overdosage and toxicity with the alphaadrenoreceptor antagonists remains very limited in the literature. In this paper, the second case in the literature with doxazosin overdosage is reported. Supportive treatment was given to the patient and the patient was discharged 48 hours after admission to the emergency department.

scholarly journals A cluster of patients with rhabdomyolysis after eating crayfish

CJEM ◽  
2017 ◽  
Vol 20 (S2) ◽  
pp. S48-S50 ◽  
Author(s):  
Wen-Xuan Yang ◽  
Kit-Ling Fan ◽  
Ling-Pong Leung
Keyword(s):  
Emergency Department ◽  
Creatine Kinase ◽  
Creatine Kinase Level ◽  
Procambarus Clarkii ◽  
Supportive Treatment ◽  
Worldwide Distribution ◽  
Freshwater Crustacean ◽  
Diet History ◽  
Haff Disease ◽  
Elevated Creatine Kinase Level

AbstractCrayfish or Procambarus clarkii is a freshwater crustacean with worldwide distribution. Tons of crayfish are consumed each year. In this report, four adult patients with rhabdomyolysis after consuming crayfish were described. All of them presented to the emergency department with myalgia. The diagnosis of rhabdomyolysis was supported by an elevated creatine kinase level. All recovered with supportive treatment. The clinical picture of these 4 patients was compatible with Haff disease. Haff disease is a syndrome in which rhabdomyolysis develops subsequent to consumption of certain cooked seafood. Crayfish is a common culprit. Diagnosis depends on obtaining a diet history and creatine kinase level. Most patients recover uneventfully with supportive treatment for rhabdomyolysis.

Management of poisoning by amphetamine or ecstasy

2016 ◽  
Author(s):  
Enno Freye
Keyword(s):  
Myocardial Infarction ◽  
Emergency Department ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Cerebral Haemorrhage ◽  
Social Classes ◽  
Acute Intoxication ◽  
Acute Effects ◽  
Important Condition ◽  
The Senses

While amphetamine and especially methamphetamine (speed) is being misused by all social classes in order to increase stamina, intellectual expansion, endurance, and euphoria, the drug 3,4-methylenedioxy-N-methylamphetamine (MDMA) (ecstasy) is preferentially abused by the younger generation for the feeling of empathy, the touching within, and enhancement of the senses. Acute intoxication differs in regard to their effects on the person. The predominant sympathetic overstimulation after methamphetamine results in cardiovascular and CNS hyperactivity accompanied by agitation and seizures, while tachycardia is a prodrome of fibrillation. The excess hypertonia often leads into myocardial infarction and may even induce cerebral haemorrhage. MDMA intoxication often seen in the emergency department is predominantly characterized by hyperthermia, the most important condition to treat, followed by rhabdomyolysis and acute renal failure. Since there is no specific antidote available, in both cases therapy consists of treatment until the acute effects are gone.

scholarly journals LO67: Alcohol-related emergency department visits by youth aged 12-24: demographics and resource utilization at Kingston Health Sciences Centre

CJEM ◽  
2020 ◽  
Vol 22 (S1) ◽  
pp. S32-S32
Author(s):  
H. Murray ◽  
L. Erlikhman ◽  
T. Graham ◽  
M. Walker
Keyword(s):  
Mental Health ◽  
Emergency Department ◽  
Resource Use ◽  
Standard Form ◽  
Emergency Department Visits ◽  
Acute Intoxication ◽  
Mental Health Issue ◽  
Male Predominance ◽  
Ed Visits ◽  
The Impact

Introduction: Recent evidence shows an increase in alcohol-related emergency department (ED) visits among youth. We sought to quantify the impact of ED visits (type and frequency, patient characteristics and resource use) related to alcohol in our centre. Methods: This was a chart review of patients aged 12-24 with alcohol-related ED visits between Sept 2013-Aug 2017. The National Ambulatory Care Reporting System (NACRS) database was searched for visits alcohol related ICD-10 codes. The Canadian Hospital Injury Reporting and Prevention Program (CHIRPP) database was also searched using the keyword alcohol. Duplicate visits were removed. Visits were excluded if patients had a history of psychosis, were held in the ED for psychiatric assessment, were homeless, were inmates from a correctional institute, if alcohol use was not mentioned and for complaints of sexual assault/intimate partner violence. Data was abstracted by two reviewers using a standard form with predetermined variables. Differences were resolved with third party adjudication. Interrater reliability of the reviewers was assessed with Kappa scores through duplicate review of 10% of randomly selected charts. A further 10% were assessed by a 3rd reviewer for extraction accuracy. Results: 3,256 ED visits were identified with 777 removed via predefined exclusion criteria. 2,479 visits were reviewed with a male predominance (54.3%). More than half of all patients (50.9%) arrived via ambulance. Assigned CTAS levels were Resuscitation: 1% Emergent: 9.9% Urgent: 48.2% Less Urgent: 35.7% Non-Urgent: 4.2% (missing 1%). The median LOS was 2.9 hrs (IQR 1.8-4.6). All visits were subclassified into mutually exclusive categories: injury (51.8%), acute intoxication (45.1%) and mental health issue (3.2%). Males were more likely to present with injury (62.4% vs 42.6%, p < 0.01). Females were more likely to present with acute intoxication (53.3% vs 46.7%, p <0.01) and mental health issues (59.5% vs 40.5%, P = 0.01). ED resource use was notable: 483 (19.4%) had imaging tests and 1216 (49.1%) had some medical intervention (blood test, fluids or medication). 57 (2.3%) patients were admitted and there was one death from an alcohol related MVC. Conclusion: Alcohol-related ED visits by youth are common in our centre and utilize substantial prehospital and in-hospital resources. Identification of effective harm reduction strategies should be a research priority.

scholarly journals Acute intoxication cases admitted to the emergency department of a university hospital

2015 ◽  
Vol 6 (1) ◽  
pp. 54 ◽  
Author(s):  
Ertugrul Kaya ◽  
Aylin Yilmaz ◽  
Ayhan Saritas ◽  
Serdar Colakoglu ◽  
Davut Baltaci ◽  
...  
Keyword(s):  
Emergency Department ◽  
University Hospital ◽  
Acute Intoxication

Assessment of patients who presented to the emergency department with mushroom poisoning

2014 ◽  
Vol 34 (7) ◽  
pp. 725-731 ◽  
Author(s):  
S Colak ◽  
H Kandis ◽  
MA Afacan ◽  
MO Erdogan ◽  
H Gunes ◽  
...  
Keyword(s):  
Emergency Department ◽  
Activated Charcoal ◽  
Conventional Therapy ◽  
Demographic Characteristics ◽  
Mushroom Poisoning ◽  
Supportive Treatment ◽  
Laboratory Findings ◽  
International Normalised Ratio ◽  
The Mean ◽  
Latent Phase

Objective: This study aimed to assess the demographic characteristics, emergency department (ED) complaints, laboratory findings, and latent phase periods of patients who presented to the ED due to mushroom poisoning (MP) as well as the efficacy of conventional and hemofiltration therapies. Method: The study was conducted on patients who presented to the ED with MP between 2010 and 2012. The patient’s demographic characteristics, complaints at the ED, latent phases, laboratory findings, and treatments of MP cases were evaluated. Results: The mean age of patients was 38.03 ± 15.96, where 63.8% of them were female and 36.2% were male. Visits occurred most frequently in the autumn (32.6%). When presenting to the ED, the most frequent complaint was nausea–vomiting. The aspartate aminotransferase (AST), alanine aminotransferase (ALT), international normalised ratio (INR), and blood urea nitrogen values of patients with a latent phase between 0 h and 5 h were significantly lower than the values of patients with a latent phase between 6 h and 24 h. In this study, 62% of the patients ( n = 36) had stomach lavage and received activated charcoal. Altogether, 55.2% of the patients had received conventional therapy, 37.9% of them received hemofiltration, and all of them received supportive treatment. The AST, ALT, and INR values of those who had received hemofiltration and conventional therapies were significantly higher than of those who received only supportive treatment ( p < 0.01). Conclusion: Hemofiltration, in combination with conventional therapy, seems to be an effective treatment for reducing mortality in suspected MP cases involving late acting toxins.

scholarly journals Acute renal failure due to Brucella melitensis

2011 ◽  
Vol 5 (12) ◽  
pp. 893-895 ◽  
Author(s):  
Ozgur Dagli ◽  
Mehmet Dokur ◽  
Gulcihan Guzeldag ◽  
Yelda Ozmen
Keyword(s):  
Emergency Department ◽  
Renal Failure ◽  
Acute Renal Failure ◽  
Brucella Melitensis ◽  
Rare Complication ◽  
Clinical Status ◽  
Renal Involvement ◽  
Blood Cultures ◽  
Low Grade ◽  
Supportive Treatment

We present the case of a 42-year-old male patient who applied to the emergency department of our hospital with clinical nephritis, orchitis, acute renal failure without endocarditis, and a low-grade fever. Brucella agglutinin titers were 1:160, Rose Bengal test was positive and Brucella melitensis was isolated from urine and blood cultures.. A combination of oral rifampin (600 mg/day) and doxycycline (200 mg/day) was administered along with supportive treatment leading to resolution of his clinical status by eight weeks. This was a rare complication of severe renal involvement due to brucellosis which resolved with antibiotic treatment.

Acute intoxication patients presenting to an emergency department in the Netherlands: admit or not? Prospective testing of two algorithms

2011 ◽  
Vol 29 (6) ◽  
pp. 467-472 ◽  
Author(s):  
R G A Ambrosius ◽  
M P Vroegop ◽  
F G A Jansman ◽  
C W Hoedemaekers ◽  
R E Aarnoutse ◽  
...  
Keyword(s):  
Emergency Department ◽  
The Netherlands ◽  
Acute Intoxication

scholarly journals The Impact of an Emergency Department Toxicology Team in the Management of Acute Intoxication

2007 ◽  
Vol 14 (3) ◽  
pp. 134-143 ◽  
Author(s):  
AHY Chung ◽  
SH Tsui ◽  
HK Tong
Keyword(s):  
Patient Outcome ◽  
Emergency Department ◽  
Length Of Stay ◽  
Hospital Admissions ◽  
Average Length ◽  
Effective Means ◽  
Acute Intoxication ◽  
Patient Disposition ◽  
Significant Difference ◽  
The Impact

Objective To evaluate the impact of the recently established Emergency Department (ED) Toxicology Team of Queen Mary Hospital (QMH) in the management of acute intoxication. Method A descriptive comparative study with retrospective data collection from all intoxicated and suspected intoxicated patients over two separate half-year periods in 2001 and 2006, before and after the establishment of the ED Toxicology Team in July 2005. Data on reasons of intoxication, drugs and substances involved, ED treatments, patient disposition, length of stay in ED, length of stay in hospital, patient outcome, and 30-day ED re-attendance and hospital re-admission were collected and examined. Results A total of 333 intoxicated patients were included in the study, 171 in 2001 and 162 in 2006. The basic epidemiological data were similar in both groups. There was a marked reduction in hospital admissions from 89.5% to 40.7% (P<0.01) and significant decline in average length of hospital stay from 46.8 hours to 29.2 hours (P<0.05). There was no statistically significant difference in patient outcome, 30-day ED re-attendance and hospital re-admission. Conclusion Our findings showed that the establishment of the ED Toxicology Team in QMH achieved significant reductions in hospital admissions and the length of stay in hospital in the management of patients with acute intoxication without jeopardising patient outcome. The results illustrate that the new model has a beneficial role in reducing cost and alleviating stress on hospital bed availability, therefore it can be recognised as a cost-effective means of management of acute intoxication.

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