A Comparative Study of Family-Based and Patient-Based Behavioural Management in Obsessive-Compulsive Disorder

1990 ◽  
Vol 157 (1) ◽  
pp. 133-135 ◽  
Author(s):  
M. Mehta
Keyword(s):  
Social Adjustment ◽  
Obsessive Compulsive ◽  
Similar Treatment ◽  
Compulsive Disorder ◽  
Treatment Conditions ◽  
The Family ◽  
Group A ◽  
Personality Pattern ◽  
Family Based ◽  
Group B

Thirty obsessive-compulsive patients were randomly allocated to two treatment conditions. In group A a significant family member was trained to act as cotherapist at home, whereas in group B, only the patient was seen and given home assignments. All 30 patients received a similar treatment regime of systematic desensitisation, exposure, and response prevention. The family-based approach resulted in greater improvement in anxiety, depression, obsessive symptoms, and in social adjustment in occupational and household responsibilities. The personality pattern of the family members also appeared to influence outcome.

scholarly journals Association Between Polymorphisms in GRIK2 Gene and Obsessive-Compulsive Disorder: A Family-Based Study

2010 ◽  
Vol 17 (3) ◽  
pp. 141-147 ◽  
Author(s):  
Aline S. Sampaio ◽  
Jesen Fagerness ◽  
Jacquelyn Crane ◽  
Marion Leboyer ◽  
Richard Delorme ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Family Based

The Superiority of Danger Ideation Reduction Therapy (DIRT) Over Exposure and Response Prevention (ERP) in Treating Compulsive Washing

2004 ◽  
Vol 21 (4) ◽  
pp. 251-268 ◽  
Author(s):  
Annette Krochmalik ◽  
Mairwen K. Jones ◽  
Ross G. Menzies ◽  
Ken Kirkby
Keyword(s):  
Response Prevention ◽  
Random Allocation ◽  
Symptom Change ◽  
Exposure And Response Prevention ◽  
Obsessive Compulsive ◽  
General Anxiety ◽  
Compulsive Disorder ◽  
Treatment Conditions ◽  
Dependent Variables

AbstractThe present study involved the random allocation of 22 obsessive-compulsive (OC) washer/cleaners to one of two treatment conditions: Danger Ideation Reduction Therapy (DIRT), or Exposure and Response Prevention (ERP). Participants received 12 1-hour individual clinical sessions and were assessed at pretreatment, posttreatment and at a 6-month follow-up with a battery of 17 measures assessing core obsessive-compulsive disorder (OCD) symptomatology, depression, stress, general anxiety, disease expectancy and perceived responsibility. DIRT subjects experienced significantly greater before to after-treatment reductions in symptomatology on six outcome measures. On 10 of the remaining 11 measures, posttreatment mean scores were lower in the DIRT condition than in the ERP condition, though differences between groups failed to reach significance. Of note, on 3 of the 17 measures, DIRT subjects experienced significantly greater posttreatment to follow-up symptom reduction. Finally, and most importantly, symptom change (regardless of treatment condition) was shown to significantly correlate with change in threat or disease expectancy across the trial. No relationships were found between improvements in perceived responsibility and any of the dependent variables. The findings suggest that DIRT and ERP may be working by reducing specific beliefs in threat; the former treatment being more effective in producing such change than the latter.

Speculations on Antineuronal Antibody-Mediated Neuropsychiatric Disorders of Childhood

PEDIATRICS ◽  
1994 ◽  
Vol 93 (2) ◽  
pp. 323-326 ◽  
Author(s):  
Susan E. Swedo ◽  
Henrietta L. Leonard ◽  
Louise S. Kiessling
Keyword(s):  
Sleep Disturbances ◽  
Obsessive Compulsive ◽  
Behavioral Disturbances ◽  
Obsessive Compulsive Symptoms ◽  
Antineuronal Antibodies ◽  
Compulsive Disorder ◽  
Clinical Observations ◽  
Neurological Abnormalities ◽  
Group A ◽  
The Central Nervous System

Several converging lines of evidence suggest that some behavioral and neurological abnormalities of childhood may be mediated through antineuronal antibodies.1-3 These antineuronal antibodies appear to arise in response to group A [beta]-hemolytic streptococcal (GABHS) infections and to cross-react with cells within the central nervous system (CNS).4 Based on clinical observations of children with Sydenham's chorea, Tourette's syndrome (TS), and/or obsessive-compulsive disorder (OCD), we hypothesize that neuroimmunological dysfunction secondary to anti-neuronal antibodies may result in behavioral disturbances, such as anxiety, emotional lability, obsessive compulsive symptoms, hyperactivity, and sleep disturbances; and neurological abnormalities, such as motor and phonic tics, ballismus, chorea, and choreiform movements.

scholarly journals The Work and Social Adjustment Scale: a simple measure of impairment in functioning

2002 ◽  
Vol 180 (5) ◽  
pp. 461-464 ◽  
Author(s):  
James C. Mundt ◽  
Isaac M. Marks ◽  
M. Katherine Shear ◽  
John M. Greist
Keyword(s):  
Social Adjustment ◽  
Interactive Voice Response ◽  
Reliability And Validity ◽  
Obsessive Compulsive ◽  
Consistency Test ◽  
Compulsive Disorder ◽  
Impairment In Functioning ◽  
Severity Of Depression ◽  
Internal Scale ◽  
Social Adjustment Scale

BackgroundPatients' perspectives concerning impaired functioning provide important information.AimsTo evaluate the reliability and validity of the Work and Social Adjustment Scale (WSAS).MethodData from two studies were analysed. Reliability analyses included internal scale consistency, test – retest and parallel forms. Convergent and criterion validities were examined with respect to disorder severity.ResultsCronbach's α measure of internal scale consistency ranged from 0.70 to 0.94. Test – retest correlation was 0.73. Interactive voice response administrations of the WSAS gave correlations of 0.81 and 0.86 with clinician interviews. Correlations of WSAS with severity of depression and obsessive–compulsive disorder symptoms were 0.76 and 0.61, respectively. The scores were sensitive to patient differences in disorder severity and treatment-related change.ConclusionsThe WSAS is a simple, reliable and valid measure of impaired functioning. It is a sensitive and useful outcome measure offering the potential for readily interpretable comparisons across studies and disorders.

scholarly journals An Atypical Presentation of Pediatric Acute Neuropsychiatric Syndrome Responding to Plasmapheresis Treatment

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Drew H. Barzman ◽  
Hannah Jackson ◽  
Umesh Singh ◽  
Marcus Griffey ◽  
Michael Sorter ◽  
...  
Keyword(s):  
Treatment Options ◽  
Abrupt Onset ◽  
Acute Onset ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Acute Infections ◽  
The Family ◽  
Work Up ◽  
Severe Anxiety ◽  
Very High

Here we report a case of a 15-year-old female who had originally been diagnosed and treated unsuccessfully for schizophrenia, psychosis, severe anxiety, and depression. More in-depth history revealed an abrupt onset of her symptoms with remote acute infections and many exhibited characteristics of obsessive compulsive disorder with rituals. Work-up for underlying infectious, immunodeficiency, and autoimmune causes was unrevealing except for very high levels of anti-neuronal antibodies which have been linked to Pediatric Acute-onset Neuropsychiatric Syndrome (PANS). Treatment options were discussed with the family and it was decided to use a course of plasmapheresis based on previous studies demonstrating efficacy and its safety profile. After course of therapy, there was a dramatic resolution of her psychosis, OCD traits, and anxiety. She was able to stop all of her antipsychotic and anxiety medications and resume many of her previous normal daily activities. The effect of this treatment has been sustained to the present time. This case emphasizes the importance of exploring nontraditional treatments for severe, treatment-resistant mental illness which requires a multidisciplinary approach. Further research is warranted in larger populations to investigate pathomechanisms and treatment of PANs/PANDAs.

Sign in / Sign up

Export Citation Format

Share Document