Impulsivity and Eating Disorders

1993 ◽  
Vol 162 (2) ◽  
pp. 193-197 ◽  
Author(s):  
Thomas Fahy ◽  
Ivan Eisler

Sixty-seven patients with bulimia nervosa and 29 patients with anorexia nervosa completed the Impulsiveness Questionnaire and questionnaires detailing severity of eating disorder. Bulimic patients had higher impulsivity scores than anorexic patients. Bulimics with high impulsivity scores did not have more severe eating disorders than low scorers. When 39 bulimics and 25 anorexics were interviewed about other impulsive behaviour, 51 % of bulimics and 28% of anorexics reported at least one other impulsive behaviour. Patients with so-called ‘multiimpulsive’ bulimia reported more severe eating disturbance, but this was not reflected on more reliable measures of symptoms. Thirty-nine bulimics entered an eight-week treatment trial and their progress was assessed at eight weeks, 16 weeks and one year. ‘Non-impulsive’ bulimics had a more rapid response than ‘impulsives' during treatment, but there was no difference at follow-up. There was no evidence of an association between high impulsivity trait scores and poor treatment response. It is concluded that impulsivity may shape the expression of eating disorders, but that ‘multi-impulsives' do not constitute a categorically distinct subgroup of bulimics.

2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Martina Isaksson ◽  
Ata Ghaderi ◽  
Martina Wolf-Arehult ◽  
Mia Ramklint

Abstract Background Personality has been suggested to be an important factor in understanding onset, maintenance, and recovery from eating disorders (ED). The objective of the current study was to evaluate personality style in different ED diagnostic groups as classified in the Diagnostic and Statistical Manual of Mental Disorders, Fifth edition (DSM-5). Methods The overcontrolled, undercontrolled, and resilient personality styles were compared in four groups of patients with EDs: anorexia nervosa restricting (ANr) (n = 34), anorexia nervosa binge eating/purging (ANbp) (n = 31), atypical anorexia nervosa (AAN) (n = 29), and bulimia nervosa (BN) (n = 76). These groups were compared with a group of patients with borderline personality disorder (BPD) (n = 108), and a non-clinical group (NC) (n = 444). Patient data were collected at two outpatient clinics in Uppsala, Sweden. NC control data were collected through convenience sampling. Participants filled out questionnaires assessing personality style. Results The main findings were more pronounced overcontrol reported by the ANr and AAN groups compared with the BN, BPD, and NC groups, and no significant difference in resilience between the ED and the NC groups. Considerable variability of over- and undercontrol was also found within each group. Conclusions The results replicate previous findings when EDs are classified according to current diagnostic criteria (DSM-5). Taking personality styles into account may improve our understanding of certain characteristics in EDs, such as social deficits and rigidity that are attributed to poor treatment outcome.


2017 ◽  
Vol 41 (S1) ◽  
pp. S102-S102 ◽  
Author(s):  
N. Ramoz ◽  
S. Guillaume ◽  
P. Courtet ◽  
P. Gorwood

IntroductionAnorexia nervosa (AN) is a severe psychiatric disorder. The epigenetic regulations are strongly suggested in AN. We and other groups have performed a whole-genome methylation study (methylome) in AN. We found that the differentially methylated CpG sites are located around genes involved in biological processes in link with embryonic morphogenesis, brain development and its plasticity, in particular adhesion and axon guidance. Here, we study an independent group of 40 AN patients. Furthermore, we have done a follow-up during more than one year, to compare the methylation profiles in subjects that evolve to the remission.ObjectivesOur work is to replicate the methylome study in an independent AN cohort and to characterize profiles of methylation at two times for the same subjects to compare the AN patients that convert to remitters.AimsOur goal is to identify diagnostic and prognostic epigenetic signatures for AN.MethodsOf the 40 AN patients, 18 evolved to remission. Furthermore, the blood samples of the subjects from the 2 times will be investigated, like this, each subject is its own control. Methylation of DNA is measured by using the Infinium HumanMethylation450 BeadChip technology.ResultsComparisons of AN to controls showed similar profiles of methylation involving the same biological processes as previously identified. We are comparing now the difference of methylation between the 18 remitters and the 18 actual AN, taking into account of the two times of samples.ConclusionsWe expect to characterize specific methylation signature of the prognostic of the AN remission.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2009 ◽  
Vol 40 (3) ◽  
pp. 479-486 ◽  
Author(s):  
Fernando Fernández-Aranda ◽  
Isabel Krug ◽  
Susana Jiménez-Murcia ◽  
Roser Granero ◽  
Araceli Núñez ◽  
...  

1988 ◽  
Vol 152 (6) ◽  
pp. 847-848 ◽  
Author(s):  
G. M. Holt ◽  
N. Bouras ◽  
J. P. Watson

We describe the case of a 33-year-old man with Down's syndrome and severe eating disorders. The clinical symptoms, and their difference from those of anorexia nervosa, are discussed. The patient responded well to a strict behavioural programme after long, in-patient treatment and was still well at a 2-year follow-up examination.


2021 ◽  
Author(s):  
Chengye Di ◽  
Konstantinos Letsas ◽  
Peng Gao ◽  
Qun Wang ◽  
Yanxi Wu ◽  
...  

Abstract Background: We sought to clarify the electrocardiographic and electrophysiological characteristics of ventricular arrhythmias (VAs), including idiopathic ventricular tachycardia (VT) and premature ventricular contractions (PVCs), with acute successful radiofrequency catheter ablation (RFCA) at the anterior portion of the mitral annulus (AP-MA).Methods and Results: Among 437 consecutive patients who presented with VAs for RFCA, twenty-six patients with acute successful RFCA at the AP-MA were included in this study. The ratio of the amplitude of the first positive peak (if present) vs. the nadir in the unipolar electrogram (EGM) was 0.00 – 0.03 (0.00) at the acute successful RFCA site. The time interval between the QRS onset to the maximum descending slope (D-Max) in the unipolar EGM (QRS - Uni) were 18.8 ± 13.6 ms. With bipolar mapping, the V-QRS interval was 3.75 – 17.3 (11) ms, 6 (23.1%) patients showed earliest V-QRS interval of 0 ms, and the other 20 patients (76.9%) showed V-QRS interval of 10-54 ms. The RFCA start-to-effect time was 14.1 ± 7.2 seconds in 23 patients (88.5%). In the remaining 3 patients (11.5%), the mean duration of successful RFCA were not well determined due to infrequent nature of clinical VAs during RFCA. Early (within 3 days) and late (one-year) recurrence rates were 23.1% (6 patients) and 26.9% (7 patients), respectively. The VAs disappeared 3 days later due to delayed RFCA efficacy in 2 patients (7.7%). No complications occurred during RFCA or the one-year follow up.Conclusions: AP-MA VAs are a rare but distinct subgroup of VAs. Bipolar and unipolar EGM features can help to detect the optimal RFCA site, and the QRS - Uni interval may work as a marker for guiding RFCA.


2001 ◽  
Vol 55 (7) ◽  
pp. 547-554 ◽  
Author(s):  
E Nova ◽  
P Varela ◽  
I López-Vidriero ◽  
O Toro ◽  
MJ Ceñal ◽  
...  

2017 ◽  
Vol 26 (5) ◽  
pp. 1460-1471 ◽  
Author(s):  
Valeria Zanna ◽  
Maria Chiara Castiglioni ◽  
Michela Criscuolo ◽  
Ilenia Chianello ◽  
Maria Elisei ◽  
...  

2004 ◽  
Vol 34 (8) ◽  
pp. 1395-1406 ◽  
Author(s):  
MANFRED M. FICHTER ◽  
NORBERT QUADFLIEG

Background. Since little is known about the long-term course and outcome of bulimia nervosa, the authors designed a 12-year prospective longitudinal study with five cross-sectional assessments based on a large sample of consecutively treated females with bulimia nervosa (purging type) (BN-P).Method. One hundred and ninety-six females with BN-P were assessed (1) at the beginning of treatment, (2) at the end of treatment, (3) at 2-year follow-up, (4) at 6-year follow-up, and (5) at 12-year follow-up. In self-ratings as well as expert ratings based on interviews we assessed specific eating-disorder and general psychopathology.Results. The general pattern of results over time showed substantial improvement during treatment, slight (in most cases non-significant) decline during the first two years after the end of treatment, and further improvement and stabilization until 12-year follow-up. At that point the majority of patients (70·1%) showed no major DSM-IV eating disorder, 13·2% had eating disorders not otherwise specified, 10·1% had BN-P and 2% had died. Very few had undergone transition to anorexia nervosa or binge-eating disorders. Logistic regression analyses showed that psychiatric co-morbidity was the best and most stable predictor for eating-disorder outcome at 2, 6 and 12 years.Conclusions. Course and outcome of BN-P was generally more favourable than for anorexia nervosa.


1997 ◽  
Vol 12 (7) ◽  
pp. 342-344 ◽  
Author(s):  
P Cotrufo ◽  
V Barretta ◽  
P Monteleone

SummaryIn this study, we investigated the prevalence of full syndrome (FS), partial syndrome (PS) and subclinical syndrome (SCS) eating disorders in a sample of 356 high school girls. We identified two cases of anorexia nervosa (0.56%), 14 of bulimia nervosa (3.94%) and one of binge eating disorder (0.28%) according to Diagnostic and Statistical Manual (DSM)-IV. Moreover, 17 girls (4.77%) were recognized as PS cases and 49 (13.7%) as SCS cases. A follow-up is now ongoing to explore the clinical evolution of partial and subclinical syndromes.


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