Psychosocial symptomatology, personal growth, and development among young adult patients following the diagnosis of leukemia or lymphoma.

Leukemias and lymphomas, especially Hodgkin's disease, are common cancers in young adults. Young adulthood is also a critical period for psychological and social development. The occurrence of cancer can interfere with the development of independence, self-image, and life goals of young adult patients. Young adult patients with leukemia or lymphoma, especially those with less favorable prognoses, experience areas of significant personal growth and maturation during their illness and treatment. Close family and social supports report as much psychosocial stress, and in many cases more stress, than the patients themselves, but similar patterns of personal growth are rarely seen.

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Perceived Changes in Life Meaning following Bereavement

OMEGA - Journal of Death and Dying ◽

10.2190/te7q-5g45-bety-x1tt ◽

1992 ◽

Vol 25 (4) ◽

pp. 307-318 ◽

Cited By ~ 47

Author(s):

Sarah Edmonds ◽

Karen Hooker

Keyword(s):

Personal Growth ◽

Inverse Relationship ◽

Life Goals ◽

Life Meaning ◽

Loved One ◽

Existential Meaning ◽

Close Family Member ◽

Negative Change ◽

Belief In God ◽

Close Family

Much research has documented the negative sequelae associated with death of a loved one. The goal of the present study was to investigate the possibility, alluded to by existential and humanistic theorists, that positive aspects of bereavement exist. College students who recently experienced the death of a close family member completed measures of grief-related distress, existential meaning, and answered open-ended questions regarding perceived changes in belief in God and life goals occurring as a result of their experience. A significant inverse relationship was found between grief and existential meaning. The majority of the sample reported a positive change in life goals, and these individuals had significantly higher existential meaning than those who reported a negative change in goals. Those who experienced change (positive or negative) in belief in God had higher levels of grief than those who reported no change. These results suggest that positive changes are associated with bereavement and that grief itself may serve as an impetus for personal growth.

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Management of Pediatric Liver Disease: A Descriptive Study of Adolescent and Young Adult Patients

PsycEXTRA Dataset ◽

10.1037/e626362009-001 ◽

2009 ◽

Author(s):

Rachel A. Annunziato ◽

Eyal Shemesh

Keyword(s):

Liver Disease ◽

Young Adult ◽

Descriptive Study ◽

Adult Patients ◽

Adolescent And Young Adult ◽

Pediatric Liver ◽

Pediatric Liver Disease

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Sporadic neuroendocrine neoplasms in young-adult patients: Differences in natural history, prognosis and treatment compared to adult-elderly patients

Endocrine Abstracts ◽

10.1530/endoabs.70.aep622 ◽

2020 ◽

Author(s):

Barbara Altieri ◽

Roberta Modica ◽

Filomena Bottiglieri ◽

Cicco Federica de ◽

Antongiulio Faggiano ◽

...

Keyword(s):

Young Adult ◽

Natural History ◽

Elderly Patients ◽

Adult Patients ◽

Neuroendocrine Neoplasms

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iMATRIX-Atezolizumab, a Phase 1/2 Study of the Safety, Pharmacokinetics, and Activity of Atezolizumab in Paediatric/Young Adult Patients with Previously Treated Solid Tumours

SSRN Electronic Journal ◽

10.2139/ssrn.3393724 ◽

2019 ◽

Author(s):

Birgit Geoerger ◽

C Michel Zwaan ◽

Lynley V. Marshall ◽

Jean Michon ◽

Franck Bourdeaut ◽

...

Keyword(s):

Young Adult ◽

Phase 1 ◽

Solid Tumours ◽

Adult Patients ◽

Previously Treated

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Navigating being a young adult with cerebral palsy: a qualitative study

International Journal of Adolescent Medicine and Health ◽

10.1515/ijamh-2020-0039 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Gitte Normann ◽

Kirsten Arntz Boisen ◽

Peter Uldall ◽

Anne Brødsgaard

Keyword(s):

Young Adults ◽

Cerebral Palsy ◽

Young Adult ◽

Qualitative Study ◽

Healthcare System ◽

Young Adulthood ◽

Educational Background ◽

Pediatric Care ◽

Healthcare Needs ◽

New Challenges

AbstractObjectivesYoung adults with cerebral palsy (CP) face potential challenges. The transition to young adulthood is characterized by significant changes in roles and responsibilities. Furthermore, young adults with chronic conditions face a transfer from pediatric care to adult healthcare. This study explores how living with CP affects young adults in general, and specifically which psychosocial, medical and healthcare needs are particularly important during this phase of life.MethodsA qualitative study with data from individual, semi-structured, in-depth interviews with six young adults with CP (ages 21–31 years) were transcribed verbatim and analyzed. The participants were selected to provide a maximum variation in age, gender, Gross Motor Function Classification System score and educational background. A descriptive thematic analysis was used to explore patterns and identify themes.ResultsThree themes were identified: “Being a Young Adult”, “Development in Physical Disability and New Challenges in Adulthood” and “Navigating the Healthcare System”. The three themes emerged from 15 sub-themes. Our findings emphasized that young adults with CP faced psychosocial challenges in social relationships, participation in education and work settings and striving towards independence. The transition to young adulthood led to a series of new challenges that the young adults were not prepared for. Medical challenges included managing CP-related physical and cognitive symptoms and navigating adult health care services, where new physicians with insufficient knowledge regarding CP were encountered.ConclusionThe young adults with CP were not prepared for the challenges and changes they faced during their transition into adulthood. They felt that they had been abandoned by the healthcare system and lacked a medical home. Better transitional care is urgently needed to prepare them for the challenges in young adulthood.

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GCT-08. PROTON BEAM RADIOTHERAPY FOR PEDIATRIC AND YOUNG-ADULT PATIENTS WITH INTRACRANIAL GERM CELL TUMOR

Neuro-Oncology ◽

10.1093/neuonc/noaa222.229 ◽

2020 ◽

Vol 22 (Supplement_3) ◽

pp. iii329-iii329

Author(s):

Minako Sugiyama ◽

Takayuki Hashimoto ◽

Takashi Mori ◽

Kazuya Hara ◽

Yukayo Terashita ◽

...

Keyword(s):

Young Adult ◽

Adverse Events ◽

Germ Cell ◽

Cell Count ◽

Proton Beam ◽

Adult Patients ◽

Short Term ◽

Intracranial Germ Cell Tumor ◽

X Ray ◽

Proton Beam Radiotherapy

Abstract BACKGROUND To reduce treatment-related adverse events in pediatric and young-adult patients with brain tumors, proton beam radiotherapy (PBT) has recently been performed instead of conventional X-ray radiotherapy. However, whether PBT is as effective as X-ray radiotherapy has not been sufficiently investigated, especially in patients receiving whole-ventricular irradiation. METHODS We report a retrospective observation of 15 patients with intracranial germ cell tumors (GCT), who received PBT at our institution from April 2014 to September 2019. We evaluated their clinical course, short-term adverse events, and prognosis. RESULTS/ CONCLUSION Fifteen patients (9 males and 6 females; median age 13 years) who received PBT following induction chemotherapy were analyzed. Nine patients received 23.4–27.0 GyE of whole-ventricular irradiation due to GCT in the pituitary gland, pineal body, or hypothalamic area. Three patients received 23.4 GyE of whole-brain irradiation: one of them had boost irradiation for basal ganglia. Three patients received 30.6 GyE of craniospinal irradiation (CSI). Six of the 15 patients experienced nausea (grade 2, according to the CTCAE version 4.0). Four patients, including two who received CSI, showed myelosuppression: decrease in white blood cell count, lymphocyte cell count, and neutrophil count (grade 3). No other severe short-term adverse events of >grade 2 was observed in any of the patients. At a median follow-up of 21 months (2-62 months) after irradiation. all patients are alive without recurrence. Our results may be encouraging and further investigations with a larger scale is warranted.

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Perceived Stigma as a Contextual Barrier to Early Uptake of HIV Testing, Treatment Initiation, and Disclosure; The Case of Patients Admitted with AIDS-Related Illness in a Rural Hospital in South Africa

Healthcare ◽

10.3390/healthcare9080962 ◽

2021 ◽

Vol 9 (8) ◽

pp. 962

Author(s):

Sphiwe Madiba ◽

Evelyn Ralebona ◽

Mygirl Lowane

Keyword(s):

Adult Patients ◽

Hiv Status ◽

Perceived Stigma ◽

Hospital Data ◽

Hiv Diagnosis ◽

Related Stigma ◽

Enacted Stigma ◽

Delayed Disclosure ◽

Selective Disclosure ◽

Close Family

We explored the extent to which perceived HIV-related stigma influences the disclosure and concealment of HIV status to family among adult patients hospitalised for AIDS-related illness, and described reports of negative responses and enacted stigma following disclosure. We conducted interviews with a purposeful sample of 28 adult patients in a rural South African hospital. Data analysis was deductive and inductive and followed the thematic approach. We found evidence of delayed HIV diagnosis and initiation of treatment. There was delayed and selective disclosure as well as concealment of the HIV-positive status. The disclosure was delayed for months or even years. During that time, there was active concealment of the HIV status to avoid stigma from family, friends, and community. When disclosure occurred, there was selective disclosure to close family members who would keep the secret and respond favorably. Although the participants disclosed mostly to close family, some of their post-disclosure experiences included incidents of enacted stigma and discrimination. The fear of perceived stigma and self-stigma influenced the active concealment of their HIV status from others. Continuous concealment of one’s HIV status and delayed disclosure limit the opportunities for support and care. There is a need to take into consideration the interaction between HIV-related stigma and disclosure to develop disclosure-counselling strategies in primary health care settings.

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