Pain and other symptoms in patients with hepatocellular carcinoma (HCC): A qualitative analysis.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e15187-e15187 ◽  
Author(s):  
Zeeshan Butt ◽  
Rajiv Mallick ◽  
Mary Frances Mulcahy ◽  
Al B. Benson ◽  
David Cella ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Back Pain ◽  
Side Effects ◽  
Systemic Therapy ◽  
Liver Diseases ◽  
Lower Back ◽  
Ongoing Pain ◽  
Pain Symptoms ◽  
Loss Of Appetite

e15187 Background: HCC is the second leading cause of cancer related deaths worldwide and incidence is increasing. Most HCC patients are diagnosed late-stage and with pain. Understanding the nature of pain experienced by HCC patients is complicated by co-morbid (including other liver) diseases and treatment related pain. The purpose of this study was to identify pain symptoms that are important and relevant to HCC patients who have received systemic therapy. Methods: We conducted semi-structured thematic interviews with 10 HCC patients who were currently on or previously had received oral systemic therapy (e.g., sorafenib) and had not received local or loco-regional therapy (e.g., surgery, radiation or chemo-embolization) within 4 weeks of the interview. Interviews included open elicitation of key symptoms, side effects and concerns. Patients also completed selected pain items from the FACT-Hep; items had previously been validated for patients with hepatobiliary cancers. Results: Mean age was 58 years (range 33-77); 2 patients had co-morbid cirrhosis, 1 had co-morbid hepatitis, and 4 patients had cirrhosis and hepatitis. When asked to describe the symptoms, side-effects or other issues that most significantly impact their quality of life, patients most often mentioned fatigue (n=5), diarrhea (n=5), skin toxicities (n=5), and loss of appetite (n=4). Nine patients reported experiencing pain over their HCC treatment course. Abdomen (N=7) and lower back (N=3) were the most common sites of pain; 2 patients reported only experiencing temporary pain from prior chemoembolization. The other 7 patients experienced ongoing pain, partly attributed to systemic therapy, ascites, or metastases. Ongoing abdominal and back pain were frequently not attributed to a specific cause. All patients indicated that FACT-Hep items adequately assessed their pain. Conclusions: Although pain was not a major driver of quality of life and for a few HCC patients it was transient and treatment-related, the majority of patients experienced some persistent pain. Abdominal pain and back pain were the most common pain sites for HCC patients. These results support the relevance of pain symptoms that have been previously identified as important in HCC.

scholarly journals When Eating Becomes Torturous: Understanding Nutrition-Related Cancer Treatment Side Effects among Individuals with Cancer and Their Caregivers

Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 356
Author(s):  
Brandy-Joe Milliron ◽  
Lora Packel ◽  
Dan Dychtwald ◽  
Cynthia Klobodu ◽  
Laura Pontiggia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Cancer Treatment ◽  
Food Preferences ◽  
Treatment Side Effects ◽  
Food And Nutrition ◽  
Loss Of Appetite ◽  
Living With Cancer ◽  
Depth Interviews

Individuals living with cancer often experience multiple nutrition-related side effects from cancer treatment, including changes in taste and smell, nausea, diarrhea, loss of appetite, and pain during eating. These side effects can profoundly impact nutritional status and quality of life. The purpose of this study was to explore experiences with nutrition-related cancer treatment side effects among cancer patients and their family caregivers, the way they manage such side effects, and the resulting changes in food preferences and behaviors. Structured surveys and in-depth interviews were conducted. Interviews focused on the presence and management of treatment side effects, how those changes influenced food preferences, and the extent to which they interfered with quality of life. Most patients (72%) reported treatment side effects; 61% reported that these side effects impacted their eating and drinking. Common side effects included fatigue (58%), dry mouth (30%), nausea (24%), constipation (20%) and diarrhea (20%). Six overarching qualitative themes were identified: Spiral of side effects; Pain of eating; Burden of eating; Loss of taste/change in taste; Symptom management; and Solutions. The authors conclude with implications for food and nutrition practice—moving beyond traditional recommendations of what to eat or avoid—to consider the overall patient and caregiver experience.

scholarly journals Oxygen-ozone therapy: our experience in the treatment of hard-root conflicts

Ozone Therapy ◽  
2016 ◽  
Vol 1 (2) ◽  
pp. 34
Author(s):  
Maria Laura Rosato ◽  
Marco Mainini ◽  
Margherita Luongo ◽  
Luigi Mascolo ◽  
Silvana Mattera ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Back Pain ◽  
Lower Back Pain ◽  
Positive Response ◽  
Clinical Symptoms ◽  
Significant Extent ◽  
Ozone Therapy ◽  
Lower Back ◽  
Herniated Discs

Lower back pain and sciatica are clinical symptoms with debilitating effects on the quality of life; they are extremely common in the population. The treatment of patients affected by sciatica, and in particular of those incurred by herniated discs, may be medical, physiatric, percutaneous minimally invasive surgery. In recent years, for the treatment of disc-radicular conflicts the Oxygen-Ozone (O<sub>2</sub>-O<sub>3</sub>) therapy is spreading to a more and more significant extent. We report our experience with O<sub>2</sub>-O<sub>3</sub> therapy in the treatment of herniated lumbar discs, evaluating the efficacy of the therapy in lower back pain and sciatica. We treated 32 patients with paravertebral intramuscular infiltrations of about 15 cc of the mixture of O<sub>2</sub>-O<sub>3</sub> at a concentration of 30 µg/cc: 66.6 % of the patients had a positive response to the treatment.

Cancer-related fatigue in carcinoma urinary bladder patients receiving chemotherapy: A single institutional study from northern India.

2019 ◽  
Vol 37 (7_suppl) ◽  
pp. 361-361
Author(s):  
Vineet Talwar ◽  
Varun Goel ◽  
Prasanta DASH
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Urinary Bladder ◽  
Clinical Intervention ◽  
Fear Of Pain ◽  
Cancer Related Fatigue ◽  
Northern India ◽  
Clinically Significant ◽  
Loss Of Appetite

361 Background: Fatigue is one of the most disabling phenomenon among patients receiving anti cancer treatment, which has profound effect on their Quality of life (QOL). Although clinicians across the globe acknowledge the importance of regular assessment of fatigue, however it is seldom being assessed and documented in clinical practice in India and very few studies have reported Cancer Related Fatigue among Indian population. Methods: For this study an exploratory design was adopted, using a purposive sampling method. Patients (N=206,) undergoing chemotherapy at Rajiv Gandhi Cancer Hospital and Research Center, Delhi, India; aged 18-83 years were included. The level of fatigue was assessed using 16- item Multidimensional assessment of Fatigue (MAF) scale and a semi structured in depth interview schedule. These interviews were recorded, transcribed and analyzed. Results: Irrespective of age, and education, 81% patients experience clinically significant fatigue. Extreme level of fatigue was reported by 29% patients requiring immediate clinical intervention while 52% patients reported moderate level of clinically significant fatigue. Top four psychosocial issues reported were: apprehension of CT side effects (23.5%), fear of pain (19%), Loss of appetite (17.5%) and anxiety during CT (13.5 %), followed by financial issues (11%). Among all patients, (49.5%) were aware of their diagnosis of which 8% were either fully aware or partially aware about the prognosis (23%). Conclusions: Fatigue remains one of the most important clinical parameters among majority of Carcinoma Urinary Bladder patients receiving chemotherapy, and is neither assessed by clinicians nor reported by majority of the patients. While almost one fourth of the patients report fear of chemotherapy as their pressing psychosocial concern, others report fear of pain, loss of appetite, manifest anxiety symptoms or report financial and logistics issue during CT. Various exercise, educational material and psychotherapeutic interventions should be developed to prepare and support them during their treatment for better preparedness of side effects and their management, reduced symptoms and better quality of life.

scholarly journals Assessment of a combined manual therapy and taping method for the treatment of chronic lower back pain A randomized controlled trial

2020 ◽  
Author(s):  
Stefan Schmidt ◽  
Nicolas Keim ◽  
Claudia Schultz ◽  
Dieter Sielmann ◽  
Roman Huber ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Back Pain ◽  
Lower Back Pain ◽  
Pelvic Obliquity ◽  
Chronic Lower Back Pain ◽  
Manual Treatment ◽  
Lower Back ◽  
End Of Treatment

AbstractBackgroundChronic lower back pain is the most frequent medical problem and the condition with the most years lived with disability. A pragmatic RCT was performed to assess a new treatment, Medi-Taping, which aims at reducing complaints by treating pelvic obliquity with a combination of manual treatment of trigger points and kinesio taping.Methods110 patients were randomized at two study centers either to Medi-Taping or to a standard treatment consisting of psychoeducation and physiotherapy as control. Treatment duration was three weeks. Measures were taken at baseline, end of treatment and at follow-up after two months. Main outcome criteria were lower back pain measured with VAS, the Chronic Pain Grade Scale and the Oswestry Low Back Pain Disability Questionnaire.ResultsPatients of both groups benefited from the treatment by medium to large effect sizes. All effects were pointing towards the intended direction with patients receiving Medi-Taping doing better. But at end of treatment and follow-up there were no significant differences for the primary endpoints between groups. Health related quality of life was significantly higher (p=.004) in patients receiving Medi-Taping compared to controls.ConclusionsMedi-Taping, a purported way of correcting pelvic obliquity and chronic tension resulting from it, is a treatment modality similar in effectiveness as a complex physiotherapy and patient education program.SignificanceThis RCT evaluated the effect of a combined therapy consisting of manual treatment and kinesio tape in patients with lower back pain. Patients receiving this treatment benefitted substantially but so did patients in the active control condition receiving physiotherapy and patient education. However, patients receiving the combined treatment had a significant higher quality of life.

scholarly journals Caudal Epidural for Pain Management of Prostate Cancer

2020 ◽  
Vol 3 (2) ◽  
pp. 64-67
Author(s):  
Rajesh Kumar Muniandy ◽  
Nagarajan Nagalingam
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Back Pain ◽  
Bone Pain ◽  
Lower Back ◽  
Stage 4 ◽  
Metastatic Bone Pain ◽  
Advanced Stages ◽  
Caudal Epidural

Prostate cancer is the second commonest cancer found in men. Pain can occur in both early and advanced stages of prostate cancer, with an incidence of 30-50%. The pain can be caused directly by the cancer or related to the cancer treatment. Currently, pain in prostate cancer is managed with surgery, medication, radiotherapy or chemotherapy. It can also be managed by intra-thecal morphine, psoas sheet catheter and superior hypogastric block. However, all these procedures involve risks. We present a case of Stage 4 Prostate Cancer who presented with severe lower back pain. We performed a caudal epidural, which was very successful to reduce the patient's pain and improve his quality of life. We recommend a caudal epidural should be considered as an option to manage metastatic bone pain in prostate cancer patients.

The contemporary management of nonspecific lower back pain

2019 ◽  
Vol 9 (5) ◽  
pp. 475-482 ◽  
Author(s):  
Ronaldo Fernando de Oliveira ◽  
Junior Vitorino Fandim ◽  
Iuri Fioratti ◽  
Lívia Gaspar Fernandes ◽  
Bruno Tirotti Saragiotto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Back Pain ◽  
Best Practices ◽  
Epidemiological Data ◽  
Evidence Based ◽  
Low Back ◽  
Societal Costs ◽  
Lower Back ◽  
Contemporary Management

Low back pain (LBP) is extremely common and causes an enormous burden on the society. This perspective article aims to provide an evidence-based summary in the field of LBP. More specifically, we aimed to present epidemiological data on cost, diagnosis, prognosis, prevention and interventions for patients with LBP. It is critical that both clinicians and policymakers follow best practices by using high-value care for patients with LBP. In addition, nonevidence-based procedures must be immediately abandoned. These actions are likely to reduce societal costs and will improve the quality of life of these patients.

scholarly journals Association of Mechanical Low Back Pain and Quality of Life in Security Guards

2021 ◽  
Vol 11 (4) ◽  
pp. 153-156
Author(s):  
Mansi Manoj Muly ◽  
Hally Shah ◽  
Asmaa Shaikh
Keyword(s):  
Quality Of Life ◽  
Back Pain ◽  
Musculoskeletal Pain ◽  
Lower Back Pain ◽  
World Health ◽  
Musculoskeletal Discomfort ◽  
Cross Sectional ◽  
Security Guards ◽  
Lower Back

Musculoskeletal Pain affects the bones & soft tissue musculatures. It can be acute or chronic. It can be localized or widespread. Lower back pain (LBP) is the most common type of musculoskeletal pain. It is one of the causes of absenteeism of employees from their work and significantly affecting their quality of life (QoL). Security guards usually involves standing for long duration. Therefore LBP is quite common in them. Changes in posture or poor body mechanics may bring about spine related problems, therefore causing other muscles to be misused and become painful. Very few literatures are available worldwide on prevalence of mechanical LBP & its relation to the QoL in standing workers. Therefore, the aim is to find out the correlation of mechanical LBP and QoL in security guards. Cross sectional study design was chosen for the research. From ninety security guards (male & female, aged 30-50 years) were screened on Cornell Musculoskeletal Discomfort Questionnaire (CMDQ). Thirty-one security guards were selected after screening, those who met the inclusion criteria (1.5 and above on CMDQ for lower back), informed consent was taken and further assessed on Oswestry LBP Disability Questionnaire (OLBPDQ) and World Health Organization QoL-BREF (WHO-QoL-BREF). In the study, moderately negative correlation was found between the OLBPDQ score & all QoL domains (-0.3, -0.1, -0.5, -0.2), which showed a significant lower QoL domains with severe LBP. Key words: Mechanical Lower back pain, Standing workers, Quality of life.

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