Overuse of five expensive oncology pharmaceuticals in the southeastern United States: A physician-level analysis.

2014 ◽  
Vol 32 (30_suppl) ◽  
pp. 33-33
Author(s):  
Charles L. Bennett ◽  
Dinah Faith Q. Huff ◽  
William S. Shimp ◽  
Anmol Baranwal ◽  
Avinash Mamgain ◽  
...  
Keyword(s):  
United States ◽  
Southeastern United States ◽  
The United States ◽  
Specific Drug ◽  
Wall Street ◽  
Related Factors ◽  
High User ◽  
The Wall Street Journal ◽  
Oncology Providers ◽  
Very High

33 Background: The Wall Street Journal recently identified that the highest rates of use of erythropoietin to Medicare-covered persons with cancer in the United States was by 11 oncologists who practiced in Florida (WSJ, June 20, 2014). We asked a related, but similar question: Could chemotherapy claims databases be used to identify individual physicians in the southeastern United States who had high rates of prescribing five expensive oncology agents: levoleucovorin (Fusilev), palonosetron plus fosapretitant (Aloxi+Emend), peg-filgastrim (Neulasta), albumin-paclitaxel (Abraxane), and epoetin/darbepoetin? Methods: Chemotherapy requests for more than 2,000 oncologists who practiced in the southeastern United States for the years 2012- 2014 were reviewed. A “high user” oncology provider for a specific drug was operationally defined as an individual whose number of prescriptions for the specific drug was more than 2 standard deviations above that for other oncology providers whose chemotherapy requests were also contained in the same database. Results: Two out of 1,479 oncology providers were identified as “extremely high users” of expensive oncology drugs (operationally defined as a high user for 5 of the 5 study drugs), two were “very high users” of expensive oncology drugs (a high user for 4 of the 5 study drugs), and 25 were “high users” (a high user for three of the five study drugs). The overwhelming majority of oncology providers (1,450) were neither extremely high, very high, nor even high users of the five study drugs. Conclusions: In the Southeastern United States, a small number of oncology physicians are extremely high, very high, and high users of expensive oncology drugs. Additional studies are needed to evaluate case-mix and other patient-related factors that might explain this finding. Focused quality improvement initiatives might also be considered. [Table: see text]

RAILROAD INVESTING AND THE IMPORTANCE OF FINANCIAL ACCOUNTING INFORMATION IN 1880s AMERICA

2013 ◽  
Vol 40 (2) ◽  
pp. 55-89 ◽  
Author(s):  
Joel E. Thompson
Keyword(s):  
United States ◽  
Information Sources ◽  
Accounting Information ◽  
The United States ◽  
Financial Accounting ◽  
Wall Street ◽  
New Information ◽  
Other Information ◽  
Comprehensive Search ◽  
The Wall Street Journal

This study has a two-fold purpose. First, it seeks to determine the importance of financial accounting information to railroad investors (and speculators) in 1880s America. Second, a further goal is to ascertain what financial accounting information was readily available for use by these investors. Based on a comprehensive search of books of the era, the 1880s were a time of expanding advice for railroad securities holders that required the use of financial accounting information. Furthermore, new information sources arose to help service investors' needs. Statistics by Goodsell and The Wall Street Journal were two such sources. This article reviews these publications along with the ongoing Commercial and Financial Chronicle and Poor's Manual of the Railroads of the United States. Each of these sources helped railroad investors to follow contemporary advice of gathering financial accounting and other information when investing.

scholarly journals Financial discourse of the 2007–2008 crisis: From unpredictability and explosion to predictability

2018 ◽  
Vol 46 (2/3) ◽  
pp. 282-293
Author(s):  
Griselda Zárate ◽  
Homero Zambrano
Keyword(s):  
United States ◽  
Financial Crisis ◽  
Economic Crisis ◽  
Wall Street Journal ◽  
Inflection Point ◽  
Wide Spectrum ◽  
The United States ◽  
Wall Street ◽  
The Wall Street Journal ◽  
The Moment

This paper aims to identify the inflection point in financial discourse, the moment of explosion and unpredictability in the 2007–2008 economic crisis, through an analysis of metaphors, and its relation to the concept of jumps in finance. The corpus is formed by articles dating from 2007–2008 published in The Wall Street Journal and related to the movements of the Standard & Poor’s 500 index (S&P500) of the United States. For the purposes of this paper, two texts are analysed: “Traders in Lehman, AIG held out hope – Friday”, and the speech “Four questions about the financial crisis” by Ben S. Bernanke. What is of particular interest is the transformation of unpredictability to predictability, as incorporated in this type of discourse to indicate a predetermined chain of events, chosen from a wide spectrum of possibilities. The theoretical framework draws on Juri Lotman’s views on the concepts of explosion, unpredictability, inflection point and predictability.

On the Relationship between Market Sentiment and Commercial Real Estate Performance—A Textual Analysis Examination

2019 ◽  
Vol 41 (4) ◽  
pp. 605-637 ◽  
Author(s):  
Eli Beracha ◽  
Marcel Lang ◽  
Jochen Hausler
Keyword(s):  
Real Estate ◽  
Textual Analysis ◽  
The United States ◽  
Real Estate Market ◽  
Commercial Real Estate ◽  
Wall Street ◽  
Related Factors ◽  
Market Sentiment ◽  
Bidirectional Relationship ◽  
The Wall Street Journal

We examine whether and the extent to which news-based sentiment, captured by textual analysis, can predict the performance of the private commercial real estate market in the United States. Our results show that sentiment reflected in news abstracts of The Wall Street Journal predicts returns of commercial real estate up to four quarters in advance. These findings are statistically significant and persist even when controlling for other related factors. This suggests that news-based sentiment can serve as an early market indicator. We are the first to examine the bidirectional relationship between sentiment, measured by textual analysis, and the performance of the private U.S. commercial real estate market. The findings contribute to the academic literature, and carry practical implications for real estate professionals.

scholarly journals US media’s coverage of China’s handling of COVID-19: Playing the role of the fourth branch of government or the fourth estate?

2021 ◽  
Vol 6 (1) ◽  
pp. 8-23
Author(s):  
Wenshan Jia ◽  
Fangzhu Lu
Keyword(s):  
United States ◽  
Wall Street Journal ◽  
The United States ◽  
Food Culture ◽  
Wall Street ◽  
Health Crisis ◽  
Mainstream Media ◽  
The Wall Street Journal ◽  
Media Reports ◽  
Domestic Affairs

The present study is an analysis of a sample of reports on China’s handling of COVID-19 by several major US media with a focus on a controversial op-ed by the Wall Street Journal. It is found that instead of covering it objectively as a public health crisis, these media reports tend to adopt the strategy of naming, shaming, blaming, and taming against China. In other words, they seize the outbreak of COVID-19 in Wuhan as an opportunity to serve Trump’s “America First” doctrine by a coordinated attempt to destroy the Chinese dream and arresting China’s ascendency. First, the naming/shaming technique is used to tarnish China’s image as a virus. The op-ed on the Wall Street Journal describes China as “the real sick man of Asia.” In addition, a cluster of ferociously negative names are slung onto China to describe the coronavirus as “the Wuhan virus,” “the Belt & Road Initiative pandemic,” “the China virus,” and so on. Second, the blaming technique is applied. On top of such negative name-calling, these media tend to blame the Chinese leadership, the political system, and finally Chinese food culture for eating pangolins. Finally, the taming technique is used to constrain, isolate, or quarantine China. One goal behind such a China threat strategy is to fan American or foreign businesses to move (back) to the United States out of China. Another goal is to create the public opinion environment that would be conducive to some American groups’ litigations against China. It is concluded that American mainstream media while quarreling with the Trump administration for domestic affairs seem to be colluding with the conservative intellectual base in the United States in supporting Trump’s strategy to knock down and divide China.

Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy

Science ◽  
2021 ◽  
Vol 371 (6536) ◽  
pp. eaax9050
Author(s):  
Steffen Breinlinger ◽  
Tabitha J. Phillips ◽  
Brigette N. Haram ◽  
Jan Mareš ◽  
José A. Martínez Yerena ◽  
...  
Keyword(s):  
United States ◽  
Aquatic Vegetation ◽  
Southeastern United States ◽  
Hydrilla Verticillata ◽  
Toxin Production ◽  
The United States ◽  
Biosynthetic Gene Cluster ◽  
Biosynthetic Gene ◽  
Bald Eagles ◽  
Cyanobacterial Species

Vacuolar myelinopathy is a fatal neurological disease that was initially discovered during a mysterious mass mortality of bald eagles in Arkansas in the United States. The cause of this wildlife disease has eluded scientists for decades while its occurrence has continued to spread throughout freshwater reservoirs in the southeastern United States. Recent studies have demonstrated that vacuolar myelinopathy is induced by consumption of the epiphytic cyanobacterial species Aetokthonos hydrillicola growing on aquatic vegetation, primarily the invasive Hydrilla verticillata. Here, we describe the identification, biosynthetic gene cluster, and biological activity of aetokthonotoxin, a pentabrominated biindole alkaloid that is produced by the cyanobacterium A. hydrillicola. We identify this cyanobacterial neurotoxin as the causal agent of vacuolar myelinopathy and discuss environmental factors—especially bromide availability—that promote toxin production.

scholarly journals Fungicide Rotation Programs for Managing Phytophthora Fruit Rot of Watermelon in Southeastern United States

2017 ◽  
Vol 18 (1) ◽  
pp. 28-34 ◽  
Author(s):  
Chandrasekar (Shaker) S. Kousik ◽  
Pingsheng Ji ◽  
Daniel S. Egel ◽  
Lina M. Quesada-Ocampo
Keyword(s):  
United States ◽  
South Carolina ◽  
Phytophthora Capsici ◽  
Southeastern United States ◽  
Heavy Rain ◽  
Integrated Approach ◽  
The United States ◽  
Fruit Rot ◽  
Management Options ◽  
Before And After

About 50% of the watermelons in the United States are produced in the southeastern states, where optimal conditions for development of Phytophthora fruit rot prevail. Phytophthora fruit rot significantly limits watermelon production by causing serious yield losses before and after fruit harvest. Efficacy of fungicide rotation programs and Melcast-scheduled sprays for managing Phytophthora fruit rot was determined by conducting experiments in Phytophthora capsici-infested fields at three locations in southeastern United States (North Carolina, South Carolina, and Georgia). The mini seedless cultivar Wonder and seeded cultivar Mickey Lee (pollenizer) were used. Five weekly applications of fungicides were made at all locations. Significant fruit rot (53 to 91%, mean 68%) was observed in the nontreated control plots in all three years (2013 to 2015) and across locations. All fungicide rotation programs significantly reduced Phytophthora fruit rot compared with nontreated controls. Overall, the rotation of Zampro alternated with Orondis was highly effective across three locations and two years. Rotations of Actigard followed by Ranman+Ridomil Gold, Presidio, V-10208, and Orondis, or rotation of Revus alternated with Presidio were similarly effective. Use of Melcast, a melon disease-forecasting tool, may occasionally enable savings of one spray application without significantly impacting control. Although many fungicides are available for use in rotations, under very heavy rain and pathogen pressure, the fungicides alone may not offer adequate protection; therefore, an integrated approach should be used with other management options including well-drained fields.

scholarly journals Cold Hardiness and Vernal Budbreak of Rhamnus caroliniana and the Invasive Rhamnus cathartica

2006 ◽  
Vol 131 (3) ◽  
pp. 345-351 ◽  
Author(s):  
J. Ryan Stewart ◽  
William R. Graves ◽  
Reid D. Landes
Keyword(s):  
United States ◽  
Water Stress ◽  
Cold Hardiness ◽  
Southeastern United States ◽  
The United States ◽  
Rhamnus Cathartica ◽  
Small Tree ◽  
Natural Distribution ◽  
Ecological Problems ◽  
Managed Landscapes

Carolina buckthorn [Rhamnus caroliniana Walt. or Frangula caroliniana (Walt.) Gray] is an attractive and water-stress-resistant shrub or small tree distributed extensively in the southeastern United States that merits use in managed landscapes. Due to substantial climatic differences within its distribution (30-year normal midwinter minima range from 13 to -8 °C), selection among provenances based on differences in cold hardiness is warranted. Before selections are marketed, the potential of carolina buckthorn to be invasive also merits investigation. Ecological problems resulting from the introduction of Rhamnus L. species in the United States, most notably the dominance of R. cathartica L. (common buckthorn) over neighboring taxa, are due in part to early budbreak. Consequently, we investigated depth of cold hardiness and vernal budbreak of carolina buckthorn and common buckthorn. Stem samples of carolina buckthorn and common buckthorn collected in midwinter survived temperatures as low as -21 and -24 °C, respectively. Although the cold hardiness of carolina buckthorns from Missouri was greater than that of carolina buckthorns from Ohio and Texas on 2 Apr. 2003, there were no differences in cold hardiness of stems from Missouri and Texas on all three assessment dates in the second experiment. All plants survived at both field locations except for the carolina buckthorns from southern Texas planted in Iowa, which showed 0% and 17% survival in 2003 and 2004, respectively. Budbreak of both species with and without mulch in Ames, Iowa, was recorded from 9 Apr. to 10 May 2002. Mean budbreak of common buckthorn was 5.7 days earlier than budbreak of carolina buckthorn, and buds of mulched carolina buckthorns broke 4.2 days earlier than did buds of unmulched carolina buckthorns. We conclude that the cold hardiness of carolina buckthorn is sufficient to permit the species to be planted outside of its natural distribution. Populations of carolina buckthorn in Ohio and Missouri should be the focus of efforts to select genotypes for use in regions with harsh winters. Phenology of its budbreak suggests carolina buckthorn will not be as invasive as common buckthorn, but evaluation of additional determinants of invasiveness is warranted.

Perceived Mother–Father Dyad Parenting Typologies Across Four Regions in the United States

2021 ◽  
pp. 0192513X2110551
Author(s):  
Melanie Stearns ◽  
Erica Szkody ◽  
Cliff McKinney
Keyword(s):  
United States ◽  
Emerging Adults ◽  
Parenting Style ◽  
Parenting Styles ◽  
Online Survey ◽  
The United States ◽  
The West ◽  
Mothers And Fathers ◽  
Paternal Parenting ◽  
Very High

Although much research has investigated parenting styles, few studies have examined parenting across regions of the United States. The current study used a nationwide sample to examine perceived maternal and paternal parenting in four regions of the United States: Northeast, South, Midwest, and West. Participants included 1080 emerging adults who answered questionnaires regarding their perceptions of maternal and paternal parenting styles using an online survey. In all regions, the largest profile indicated a parenting style of High Authoritative/Authoritarian and Moderate Permissive mothers and fathers. Similarly, all regions indicated profiles that were High or Very High Authoritarian mothers and fathers. All regions except the West had a profile with High Authoritative mothers and High or Very High Authoritarian fathers. The Northeast, South, and West also had unique profiles found only in those regions. Thus, results indicate similarities as well as distinct differences in parenting style across regions of the United States.

Sign in / Sign up

Export Citation Format

Share Document