The impact of patient characteristics on voiding symptoms, irritative symptoms, and sexual function, following stereotactic body radiotherapy for prostate cancer.

2015 ◽  
Vol 33 (7_suppl) ◽  
pp. 245-245
Author(s):  
Zaker Hamid Rana ◽  
Robert Hong ◽  
Donald McRae ◽  
Gregory Bernstein ◽  
Robert Mordkin ◽  
...  
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Stereotactic Body Radiotherapy ◽  
Patient Characteristics ◽  
Patient Age ◽  
Prostate Radiotherapy ◽  
Voiding Symptoms ◽  
Patient Âgé ◽  
Prostate Size ◽  
The Impact

245 Background: Urinary symptoms and sexual dysfunction are the two most common complaints following prostate radiotherapy. There is limited clinical data evaluating the impact of baseline patient characteristics on response to hypofractionated treatment. This study sought to evaluate how patient age and prostate size affects voiding symptoms, irritative symptoms, and sexual function, following stereotactic body radiotherapy (SBRT). Methods: This retrospective analysis includes 102 non-metastatic patients treated with SBRT at a single institution between May 2008 and September 2014. The course of radiotherapy consisted of 36.25 Gy (range 35–40) over 5 daily fractions. International Prostate Symptom Score (IPSS) and Sexual Health Inventory for Men (SHIM) were recorded at baseline, 1, 3, 6, 9, 12, 18, 24, and 36 months after treatment. Results: Median patient age was 68 years old (range 47-88) and median prostate volume was 43 cc (range 18.7-170.7). Baseline IPSS irritative score, IPSS voiding score, and SHIM score were 5.34, 5.42, and 13.55. A statistically significant increase in voiding (7.02), irritative (7.21), and decrease in SHIM score (11.77) was observed after one month (p < .05). The IPSS irritative score and IPSS voiding scores returned to baseline in >90% of patients by 9 months and SHIM scores returned to baseline in >90% of patients by 2 years. Prostate size ≤ 50 cc showed higher baseline IPSS voiding and irritative resolution rates after 3 months (p < .05). Conclusions: While an increase in IPSS irritative score, and a decrease in SHIM score initially occurred, all symptoms return to baseline within three years. Age did not affect urinary or sexual dysfunction following radiotherapy. Patients with smaller prostate volumes had significantly better voiding and irritative outcomes when compared to larger volumes.

The impact of patient age and comorbidities on the occurrence of “never events” in cerebrovascular surgery: an analysis of the Nationwide Inpatient Sample

2014 ◽  
Vol 121 (3) ◽  
pp. 580-586 ◽  
Author(s):  
Timothy Wen ◽  
Shuhan He ◽  
Frank Attenello ◽  
Steven Y. Cen ◽  
May Kim-Tenser ◽  
...  
Keyword(s):  
Hospital Costs ◽  
Patient Characteristics ◽  
High Risk Population ◽  
Health Care Administrators ◽  
Patient Age ◽  
Medical Comorbidities ◽  
Patient Âgé ◽  
Never Events ◽  
Tract Infections ◽  
The Impact

Object As health care administrators focus on patient safety and cost-effectiveness, methodical assessment of quality outcome measures is critical. In 2008 the Centers for Medicare and Medicaid Services (CMS) published a series of “never events” that included 11 hospital-acquired conditions (HACs) for which related costs of treatment are not reimbursed. Cerebrovascular procedures (CVPs) are complex and are often performed in patients with significant medical comorbidities. Methods This study examines the impact of patient age and medical comorbidities on the occurrence of CMS-defined HACs, as well as the effect of these factors on the length of stay (LOS) and hospitalization charges in patients undergoing common CVPs. Results The HACs occurred at a frequency of 0.49% (1.33% in the intracranial procedures and 0.33% in the carotid procedures). Falls/trauma (n = 4610, 72.3% HACs, 357 HACs per 100,000 CVPs) and catheter-associated urinary tract infections (n = 714, 11.2% HACs, 55 HACs per 100,000 CVPs) were the most common events. Age and the presence of ≥ 2 comorbidities were strong independent predictors of HACs (p < 0.0001). The occurrence of HACs negatively impacts both LOS and hospital costs. Patients with at least 1 HAC were 10 times more likely to have prolonged LOS (≥ 90th percentile) (p < 0.0001), and 8 times more likely to have high inpatient costs (≥ 90th percentile) (p < 0.0001) when adjusting for patient and hospital factors. Conclusions Improved quality protocols focused on individual patient characteristics might help to decrease the frequency of HACs in this high-risk population. These data suggest that risk adjustment according to underlying patient factors may be warranted when considering reimbursement for costs related to HACs in the setting of CVPs.

The impact of patient age and procedure type on postoperative opioid use following ambulatory pediatric urologic procedures

2021 ◽  
Author(s):  
Michael F. Basin ◽  
Zoë G. Baker ◽  
Melissa Trabold ◽  
Terry Zhu ◽  
Lorraine I. Kelley-Quon ◽  
...  
Keyword(s):  
Opioid Use ◽  
Patient Age ◽  
Patient Âgé ◽  
The Impact ◽  
Procedure Type

The impact of sexual dysfunction on the quality of life measured by MSQoL-54 in patients with multiple sclerosis

2008 ◽  
Vol 14 (8) ◽  
pp. 1131-1136 ◽  
Author(s):  
DK Tepavcevic ◽  
J Kostic ◽  
ID Basuroski ◽  
N Stojsavljevic ◽  
T Pekmezovic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Health Distress ◽  
Pain Subscale ◽  
Related Quality ◽  
Vaginal Lubrication ◽  
The Impact

Objective Sexual dysfunction (SD) is a common but often overlooked symptom in multiple sclerosis (MS). The aim of this study was to estimate the frequency, type, and intensity of SD in our patients with MS and to investigate its influence on all the domains of quality of life. Methods The study population comprised a cohort of 109 patients with MS (McDonald's criteria, 2001). SD was quantified by a Szasz sexual functioning scale. Health-related quality of life was measured by a disease-specific instrument MSQoL-54 (Serbian version). Results The presence of at least one symptom of SD was found in about 84% of the men and in 85% of the women. The main complaints in women were reduced libido, difficulties in achieving orgasm, and decreased vaginal lubrication; in men, the main complaints were reduced libido, incomplete erections, and premature ejaculation. In women, statistically significant negative correlations between the presence and level of SD and quality of life domains were reached for all subscales ( P < 0.01), except for the Pain subscale ( P = 0.112). In men, negative correlations were also observed for all domains, but they were statistically significant for physical health, physical role limitations, social function, health distress, sexual function, and sexual function satisfaction ( P < 0.01). We found that the presence of all the analyzed types of sexual problems statistically significantly lowered scores on the sexual function and the sexual function satisfaction subscales in both men and women ( P < 0.01). The most prominent impact on both domains was observed for the total loss of erection in men and for anorgasmia in women. Conclusions Our results reveal that frequent occurrence of SD in MS patients prominently affects all aspects of their quality of life.

scholarly journals Impact of an Educational Program on Sexual Issues among Cervical Cancer Survivors' Women in Northern Upper Egypt

2021 ◽  
Vol 5 (1) ◽  
pp. 01-15
Author(s):  
Hanan Elzeblawy Hassan ◽  
Ragaa Mohammed ◽  
Soad Ramadan ◽  
Hagar Masaud
Keyword(s):  
Cervical Cancer ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Cancer Survivors ◽  
Educational Program ◽  
Gynecological Cancer ◽  
Upper Egypt ◽  
Sexual Distress ◽  
Distress Scale ◽  
The Impact

Background: Sexuality is an important part of normal human functioning. Gynecological cancer and its treatments can affect one or more phases of the sexual response cycle, through alterations of sexual function. Sexual dysfunction is one of the most distressful symptoms among cervical cancer survivors. Sexual distress is a broad term encompassing any sexual discomfort and dysfunction. Sexual difficulties following cervical cancer can be stressful for couples as it can feel like a core part of the relationship has disappeared. Aim: The study is conducted to evaluate the impact of an educational program on sexual issues (sexual dysfunction & sexual distress) among cervical cancer survivors' women in Northern Upper Egypt. Methods; Design: A quasi-experimental design. Setting: out-patient clinic in the oncology unit at Beni-Suef University Hospital. Subjects: A purposive sample of 70 women. Tools: structured interviewing questionnaire sheet, female sexual function index, and female sexual distress scale. Results: The results of the study revealed regression of all items of women’s sexual distress scores, and progression of all items of women’s sexual items post-program compared to pre-one. Conclusion: The teaching program was very effective in improving sexuality among cervical cancer survivors' women. Recommendations: Disseminate the educational booklet at health centers and oncology outpatients. Integrate psychologist, psychosexual specialist, and social worker in treatment and counseling program for women with cervical cancer in the early stage of their treatment.

The Impact of Urethroplasty on Voiding Symptoms and Sexual Function

Urology ◽  
2011 ◽  
Vol 78 (1) ◽  
pp. 198-201 ◽  
Author(s):  
Emilie K. Johnson ◽  
Jerilyn M. Latini
Keyword(s):  
Sexual Function ◽  
Voiding Symptoms ◽  
The Impact

scholarly journals The Impact of Metabolic Syndrome and Its Components on Female Sexual Dysfunction: A Narrative Mini-Review

2018 ◽  
Vol 12 (2) ◽  
pp. 57-63
Author(s):  
Simona Di Francesco ◽  
Marika Caruso ◽  
Iole Robuffo ◽  
Andrea Militello ◽  
Elena Toniato
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Sexual Dysfunction ◽  
Arterial Hypertension ◽  
Sexual Function ◽  
Sexual Desire ◽  
Female Sexual Dysfunction ◽  
Systemic Arterial Hypertension ◽  
The Metabolic Syndrome ◽  
The Impact

Background: The impact of metabolic syndrome on female sexual dysfunction received modest consideration in clinical practice. The aim of the research was to analyze the international literature to determine the relationship between the metabolic syndrome, its components and female sexual disorders. Methods: We identified relevant full-length papers by electronic databases as Index Medicus/Medline, Scopus, Life Science Journals, from 2005 to the present. Studies were searched using the following as search query: metabolic syndrome, female sexual dysfunction, obesity, systemic arterial hypertension, diabetes mellitus, dyslipidemia. Results: Women with metabolic syndrome showed higher prevalence of sexual inactivity and low sexual desire, orgasm and satisfaction respect to women without metabolic syndrome. Particularly metabolic components as diabetes mellitus, dy-slipidemia, systemic arterial hypertension were strongly associated with lower sexual desire, activity and Female Sexual Function Index total score. In contrast, other studies showed no relationship. Conclusion: Our study showed that in the clinical evaluation of women with metabolic syndrome routine inquiring about female sexual dysfunction should be recommended to ameliorate sexual function and quality of life. However more prospective and longitudinal studies on the sexual effects of metabolic syndrome should also be suggested to know the factors related to women's sexuality better.

Chondrocyte Viability After Intra-articular Calcaneal Fractures in Humans

2007 ◽  
Vol 28 (6) ◽  
pp. 665-668 ◽  
Author(s):  
Scott T. Ball ◽  
Kyle Jadin ◽  
R. Todd Allen ◽  
Alexandra K. Schwartz ◽  
Robert L. Sah ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Calcaneal Fractures ◽  
Patient Age ◽  
Chondrocyte Viability ◽  
Articular Fractures ◽  
Patient Âgé ◽  
Post Traumatic ◽  
The Impact ◽  
Traumatic Arthritis ◽  
Time From Injury

Background: Chondral damage from the impact of injury may contribute to the high incidence of post-traumatic arthritis after calcaneal fractures, but this has yet to be proven. We sought to study the effect of intra-articular calcaneal fractures on chondrocyte viability and to correlate these effects with injury severity, time from injury to surgery, and patient age and co-morbidities. Methods: Irreducible osteochondral fragments from 12 patients undergoing operative treatment for intra-articular calcaneal fractures were analyzed. Control cartilage was obtained from four tissue donors who died of unrelated causes. The cartilage was assessed for chondrocyte viability through the full thickness of tissue using a Live/Dead assay followed by laser scanning confocal microscopy. Patient demographics including injury classification and severity, time from injury to surgery, and patient age were recorded. Results: Chondrocyte viability from fracture patients averaged 72.8% ± 12.9% (range 53% to 95%), which was significantly lower than the 94.8% ± 1.5% viability observed in the control specimens ( p = 0.005). Chondrocyte viability declined with higher energy injuries ( p = 0.13), time from injury to surgery ( p = 0.07), and increasing patient age ( p = 0.07). However, none of these factors reached a level of statistical significance. Conclusions: A significant decline in chondrocyte viability occurs after intra-articular fractures of the calcaneus. This may contribute to the development of post-traumatic arthritis.

scholarly journals Sexual Dysfunction and Marital Relationship in Women With Schizophrenia in Comparison with Caregivers: A Hospital-based Study

2020 ◽  
Vol 2 (1) ◽  
pp. 87-92
Author(s):  
Suvarna Jyothi Kantipudi ◽  
Navina Suresh ◽  
Poornima Ayyadurai ◽  
Sathianathan Ramanathan
Keyword(s):  
Sexual Dysfunction ◽  
Sexual Function ◽  
Sexual Functioning ◽  
Cross Sectional Study ◽  
Women Caregivers ◽  
Cross Sectional ◽  
Significant Difference ◽  
Relationship Assessment ◽  
The Impact ◽  
The Relationship

Background: Sexual dysfunction is common in females with schizophrenia and is attributed to multiple causes, including individual psychopathology and antipsychotics. Understanding the impact of relationship satisfaction on sexual functioning is not widely studied in schizophrenia. Women caregivers also experience sexual problems and were not studied in the past. Aim: To assess the nature and occurrence of sexual dysfunction in women with schizophrenia in comparison to caregivers of males without severe mental disorder. Methods: A cross-sectional study was conducted. A total of 30 women with schizophrenia were recruited as cases and 26 age-matched controls were recruited from female caregivers. All subjects were assessed using standardized tools such as Female Sexual Function Index (FSFI) and Relationship Assessment Scale along with sociodemographic questionnaire. Results: There was a significant difference in FSFI scores and relationship scores between women with schizophrenia and caregiver control subjects. The relationship quality was better in patients with schizophrenia when compared to caregivers unlike sexual functioning. Conclusion: Sexual functioning in women is a complex phenomenon. A holistic biopsychosocial approach is necessary to understand women’s sexual function.

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