Resectability assessment of enhanced CT and contrast-enhanced endoscopic ultrasonography for the periampullary neoplasm.

199 Background: To evaluate the efficacy of enhanced CT and contrast-enhanced endoscopic ultrasonography (CE-EUS) for assessment of the resectability of periampullary neoplasm. Methods: a prospective analysis of 93 patients with periampullary neoplasm underwent CT and CE-EUS was conducted to compare the imaging data with the surgical and pathological findings, in order to evaluate their efficacies for the resectability assessment. Results: There was no significant difference in sensitivity and specificity between CT and CE-EUS in adjacent organ invasion, lymph node metastasis and liver metastasis (p > 0.05). For the diagnosis of periampullary neoplasm and assessment of vascular invasion, CE-EUS was better than CT (94.6% vs 84.1%,P = 0.023; 96.2% vs 85.9%, P = 0.041). Logistic regression showed that the accuracy of CE-EUS in determining adjacent organ invasion was correlated with the tumor size, and vascular invasion was correlated with the tumor location and size. Conclusions: CE-EUS has advantages in the assessment of the resectability of periampullary neoplasm, especially for the assessment of vascular invasion, and can be used as a supplementary Imaging technology to the enhanced CT.

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Adrenal incidentalomas: imaging challenges—role of MDCT scan versus MRI in evaluating adrenal incidentalomas

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-021-00437-w ◽

2021 ◽

Vol 52 (1) ◽

Author(s):

Monica Maher Amin Nawar ◽

Sameh Abdel Aziz Zaky Hanna ◽

Shereen Sadik El-Sawy ◽

Sally Yehia Shokralla

Keyword(s):

Significant Risk ◽

Adrenal Incidentaloma ◽

Adrenal Incidentalomas ◽

Specific Patient ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Significant Difference ◽

Adrenal Masses

Abstract Background The term adrenal incidentaloma (AI), by definition, is an adrenal mass that is unexpectedly detected through an imaging procedure performed for reasons unrelated to adrenal dysfunction or suspected dysfunction. Despite their frequent appearance, the challenge remains in recognizing and treating the small percentage of AI that poses a significant risk, either because of their hormonal activity or because of their malignant histology. The aim of this study is to study the role of MRI, specifically chemical shift imaging (CSI), against various MDCT scans (non-enhanced, enhanced, and delayed) in the characterization of incidentally discovered adrenal masses to offer a way for the patients to avoid unnecessary time and money-wasting imaging modalities used to reach a diagnosis of their incidentally discovered adrenal lesions. We examined a total number of 20 patients with total of 22 adrenal lesions. The mean age was 51.1 ± 15.27. Results In our study, we found that among CT parameters, APW and RPW showed the highest sensitivity and specificity for detection of lipid-rich adenomas. CSI has also proven to be the best MR technique. However, there is no statistically significant difference in the diagnostic capability of CSI versus the CT washout technique. Both modalities could be conducted, according to specific patient preferences and/or limitations, with comparable highly accurate outcomes. Conclusion This study demonstrates that a similar diagnostic outcome is obtained from contrast-enhanced CT (CECT) and MRI with CSI of adrenal lesions.

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Role of Esophagectomy in Treatment of Esophageal Carcinoma with Clinical Evidence of Adjacent Organ Invasion

World Journal of Surgery ◽

10.1007/s002680020060 ◽

2001 ◽

Vol 25 (3) ◽

pp. 279-284 ◽

Cited By ~ 31

Author(s):

Toshiki Matsubara ◽

Mamoru Ueda ◽

Norihiro Kokudo ◽

Takashi Takahashi ◽

Tetsuichiro Muto ◽

...

Keyword(s):

Esophageal Carcinoma ◽

Clinical Evidence ◽

Adjacent Organ ◽

Adjacent Organ Invasion ◽

Organ Invasion

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Prognosticators and outcomes of patients with renal cell carcinoma and adjacent organ invasion treated with radical nephrectomy

Urologic Oncology Seminars and Original Investigations ◽

10.1016/j.urolonc.2015.11.020 ◽

2016 ◽

Vol 34 (5) ◽

pp. 237.e19-237.e26 ◽

Cited By ~ 6

Author(s):

Leonardo D. Borregales ◽

Dae Y. Kim ◽

Angie L. Staller ◽

Wei Qiao ◽

Arun Z. Thomas ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Radical Nephrectomy ◽

Adjacent Organ ◽

Adjacent Organ Invasion ◽

Organ Invasion

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A preoperative assessment of adjacent organ invasion by stomach carcinoma with high resolution computed tomography

Surgery Today ◽

10.1007/bf02348556 ◽

1994 ◽

Vol 24 (4) ◽

pp. 299-304 ◽

Cited By ~ 3

Author(s):

Akira Tsuburaya ◽

Yoshikazu Noguchi ◽

Akihiko Matsumoto ◽

Shoichi Kobayashi ◽

Kunihiko Masukawa ◽

...

Keyword(s):

Computed Tomography ◽

High Resolution ◽

Preoperative Assessment ◽

Stomach Carcinoma ◽

High Resolution Computed Tomography ◽

Adjacent Organ ◽

Adjacent Organ Invasion ◽

Organ Invasion

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Safety and Benefit Of Sentinel Lymph Nodes Biopsy Compared to Regional Lymph Node Dissection in Primary Vulvar Cancer Patients Without Distant Metastasis and Adjacent Organ Invasion: A Retrospective Population Study

Frontiers in Oncology ◽

10.3389/fonc.2021.676038 ◽

2021 ◽

Vol 11 ◽

Author(s):

Weili Zhou ◽

Yang Bai ◽

Yangyang Yue

Keyword(s):

Lymph Node ◽

Lymph Nodes ◽

Distant Metastasis ◽

Regional Lymph Node ◽

Invasion Depth ◽

Regional Lymph Nodes ◽

Adjacent Organ ◽

Regional Lymph Node Dissection ◽

Adjacent Organ Invasion ◽

Organ Invasion

BackgroundThe safety and benefit of sentinel lymph node biopsy (SLNB) compared with regional lymph node dissection (RLND) and no lymph nodes removed (NA) in patients with vulvar squamous cell cancer (VSCC) was not well studied.MethodsA retrospective analysis on VSCC patients without distant metastasis and adjacent organ invasion from the Surveillance, Epidemiology, and End Results Program database between 2004 and 2016 was carried out. Within subgroups stratified by negative (LN−) or positive (LN+) regional lymph node findings, inverse probability weighting (IPW) adjusted multivariate Fine-Gray compete risk (CR) model and accelerated failure time (AFT) model was used to investigate the factors associated with and cancer-specific survival (CSS) and overall survival (OS).ResultsOf the 3,161 VSCC patients treated with surgery, 287 (9.1%) underwent SLNB, 1,716 (54.3%) underwent RLND, and 1,158 (36.6%) had no regional lymph nodes removed. As illustrated by IPW adjusted multivariate regressions, SLNB was significantly associated with prolonged CSS (LN−, adjusted sub-proportional hazard ratio [sHR] = 0.42; 95% confidence interval [CI], 0.19–0.93; P=0.032; LN+, adjusted sHR = 0.29; 95% CI, 0.16–0.54, P<0.001) and OS (LN−, adjusted time ratio [TR] = 1.38; 95% CI, 0.82–2.32; P=0.226; LN+, adjusted TR = 2.68; 95% CI, 1.73–4.14; P<0.001), although the effect of SLNB on OS was not significant within the LN− cohort. Moreover, SLNB led to improved CSS (adjusted sHR = 0.40; 95% CI, 0.23–0.70; P = 0.001) and OS (adjusted TR=1.15, 95% CI 0.76-1.73, P=0.279) compared with NA. Age was a significant prognostic factor of CSS and OS, whereas tumor size, surgery type, and invasion depth were not.ConclusionsSLNB leads to significantly prolonged CSS and OS in VSCC surgery patients without distant metastasis and adjacent organ invasion than RLND, except for the similar OS in the LN− cohort. SLNB could be carried out preferentially for VSCC surgery patients without distant metastasis and adjacent organ invasion, irrespective of tumor size, surgery type, invasion depth, and regional lymph nodes metastasis. Further prospective clinical trials are warranted to confirm the findings of this study.

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BILATERAL MULTIFOCAL RENAL CELL CARCINOMA

The Professional Medical Journal ◽

10.29309/tpmj/2008.15.03.2831 ◽

2008 ◽

Vol 15 (03) ◽

pp. 400-402

Author(s):

SALMAN `RASHID ◽

MUHAMMAD ARSHAD ◽

MAZHAR SHAFIQ ◽

M. Rafiq Zafar

Keyword(s):

Renal Cell Carcinoma ◽

Ct Scan ◽

Renal Cell ◽

Lesion Size ◽

Renal Cell Carcinomas ◽

Adjacent Organ ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct

Bilateral synchronous renal cell Carcinomas occur in approximately 1-3% of all patients with RCC.Ultrasound and contrast-enhanced CT scan are the most useful tests for diagnosing and staging. US has an advantageover CT in determination of nature of the lesion (solid/cystic). CT is more sensitive in evaluation of lesion size anddetection of calcification and necrosis. CT also has an advantage over US in evaluation of perinephric extension,adjacent organ infiltration and regional lymphadenopathy. Both US and CT are equally sensitive in detection of IVCthrombus.

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Main pulmonary artery diameter assessment in a large sample of Indian population: a MDCT based study

International Journal of Scientific Reports ◽

10.18203/issn.2454-2156.intjscirep20192064 ◽

2019 ◽

Vol 5 (6) ◽

pp. 145

Author(s):

Abdul Haseeb Wani ◽

Yassar Shiekh ◽

Najeeb Tallal Ahangar

Keyword(s):

Pulmonary Artery ◽

Main Pulmonary Artery ◽

Normative Values ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Significant Difference ◽

Pulmonary Arterial ◽

The Mean ◽

Pulmonary Artery Diameter

Background: The gold standard for pulmonary artery pressure measurement is right heart catheterization but its invasive nature precludes its routine use. Main pulmonary arterial trunk calibre increase is a strong indicator of underlying pulmonary arterial hypertension. MDCT can accurately measure the diameter of main pulmonary artery. The objective of the study was to establish the normative values of main pulmonary artery caliber using contrast enhanced CT and try to ascertain any significant difference in main pulmonary artery calibers between two genders and correlation of age and main pulmonary artery diameter.Methods: Contrast enhanced CT images of 462 subjects were analysed on a PACS workstation monitor and widest diameter perpendicular to long axis of the main pulmonary artery as seen on reformatted axial image was measured with electronic caliper tool at the level of the main pulmonary artery bifurcation. Results: The mean main pulmonary artery diameter in females was 22.54±2.19 mm and 23.34±3.06 mm in males. The mean pulmonary artery diameter in males was larger than females with statistically significant difference seen (p<0.05). The correlation coefficient between age of whole sample and their mean main pulmonary artery was found to be 0.1006 with no statistically significant difference.Conclusions: There is a statistically significant difference in the mean main pulmonary artery calibre between males and females with no strong correlation between the age and mean main pulmonary artery calibre. Further studies are warranted to find the complex interaction between main pulmonary artery diameter and sex, age and body mass index.

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Extended distal pancreatectomy for pancreatic adenocarcinoma with splenic vein thrombosis and/or adjacent organ invasion

The American Journal of Surgery ◽

10.1016/j.amjsurg.2014.10.017 ◽

2015 ◽

Vol 209 (3) ◽

pp. 564-569 ◽

Cited By ~ 9

Author(s):

Alexandra M. Roch ◽

Harjot Singh ◽

Alexandra P. Turner ◽

Eugene P. Ceppa ◽

Michael G. House ◽

...

Keyword(s):

Distal Pancreatectomy ◽

Pancreatic Adenocarcinoma ◽

Splenic Vein ◽

Splenic Vein Thrombosis ◽

Adjacent Organ ◽

Vein Thrombosis ◽

Adjacent Organ Invasion ◽

Organ Invasion

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Evaluation of 18F-FDG uptake in lung parenchyma compensating for tissue fraction: Comparison between non-enhanced low dose CT and intravenous contrast-enhanced diagnostic CT

Nuklearmedizin ◽

10.1055/a-1038-9933 ◽

2019 ◽

Vol 59 (01) ◽

pp. 20-25

Author(s):

Sabine Garpered ◽

David Minarik ◽

Sophia Frantz ◽

Sven Valind ◽

Per Wollmer

Keyword(s):

Attenuation Correction ◽

Low Dose ◽

Left Lung ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Pet Ct ◽

Enhanced Ct ◽

Significant Difference ◽

18F Fdg ◽

Tissue Fraction

Abstract Aim To determine how the presence of intravenous (IV) contrast-enhanced CT influences SUV measurements corrected for both attenuation and tissue fraction. Material and Methods Eighteen patients with different malignancies, free from lung disorders, lung cancer or metastasis, were prospectively recruited when referred for staging with combined 18F-FDG-PET/CT examination. A non-enhanced low-dose CT over the chest was immediately followed by a whole-body IV contrast-enhanced diagnostic CT and finally the PET acquisition. PET data were reconstructed with attenuation correction based on the two CT data sets. The lungs were segmented in the CT images and lung density was measured. Uptake of 18F-FDG in lung parenchyma was recorded using both non-enhanced and IV contrast-enhanced CT as well as with and without compensation for lung aeration. A comparison of SUV values of corrected and uncorrected PET images was performed. Results There was no significant difference between low dose PET/CT and IV contrast-enhanced PET/CT when removing the impact of air fraction (p = 0.093 for the right lung and p = 0.085 for the left lung). When tissue fraction was not corrected for, there was a significant difference between low dose PET/CT and IV contrast enhanced PET/CT used for attenuation correction (p = 0.006 for the right lung and p = 0.015 for the left lung). Conclusion There was only a marginal effect on the assessement of SUV in the lung tissue when using IV contrast enhanced CT for attenuation correction when the air fraction was accounted for.

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