scholarly journals CYTOMEGALOVIRUS (CMV) INFECTION OF THE CENTRAL NERVOUS SYSTEM (CNS) OF SUCKLING MICE AND ITS PREVENTION BY IMMUNIZATION OF MOTHERS/NURSERS

1977 ◽  
Vol 11 (4) ◽  
pp. 503-503
Author(s):  
Donald N Medearis ◽  
C Susan Chester ◽  
Sandra Prokay
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Cmv Infection ◽  
Suckling Mice ◽  
The Central Nervous System

scholarly journals Follow-up of pregnant women with active cytomegalovirus infection

1999 ◽  
Vol 5 (5) ◽  
pp. 1049-1054
Author(s):  
H. Y. Al Ali ◽  
S. A. Yasseen ◽  
T. Y. Raof
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pregnant Women ◽  
Congenital Malformations ◽  
Cmv Infection ◽  
Serological Evidence ◽  
Congenital Cmv Infection ◽  
The Central Nervous System ◽  
Congenital Cmv

Pregnant women [60]with and without serological evidence of active cytomegalovirus [CMV]infection were followed until delivery to detect the incidence and types of overt congenital CMV infection in neonates in Mosul, Iraq. Infection was diagnosed by the detection of CMV-IgM, using ELISA. CMV-IgM was detected in cord blood samples of six [10%]overtly sick infants [with different congenital malformations]born to mothers with active CMV infection. Central nervous system abnormalities were detected in all six cases [two with microcephaly and four with hydrocephaly]. Congenital CMV infection should be suspected in infants born with congenital malformations, especially those of the central nervous system. The detection of a significant number of hydrocephalus cases in our study is notable

Level of Cytomegalovirus (CMV) DNA in Cerebrospinal Fluid of Subjects with AIDS and CMV Infection of the Central Nervous System

1995 ◽  
Vol 172 (2) ◽  
pp. 527-531 ◽  
Author(s):  
J. R. Arribas ◽  
D. B. Clifford ◽  
C. J. Fichtenbaum ◽  
D. L. Commins ◽  
W. G. Powderly ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Cmv Infection ◽  
The Central Nervous System

scholarly journals A VIRUS RECOVERED FROM THE FECES OF "POLIOMYELITIS" PATIENTS PATHOGENIC FOR SUCKLING MICE

1949 ◽  
Vol 89 (6) ◽  
pp. 567-582 ◽  
Author(s):  
Gilbert Dalldorf ◽  
Grace M. Sickles ◽  
Hildegard Plager ◽  
Rebecca Gifford
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Experimental Animal ◽  
Rhesus Monkeys ◽  
Skeletal Muscles ◽  
Suckling Mice ◽  
The Central Nervous System

A virus has been recovered from the feces of two children having symptoms similar to those of poliomyelitis. The virus is pathogenic for suckling mice and hamsters but not for rhesus monkeys. It induces striking lesions in the skeletal muscles of the experimental animal but not in the central nervous system. Other viruses inducing similar signs and lesions in suckling mice have been isolated from several other outbreaks of a poliomyelitis-like disease, including one large urban epidemic.

Effects of Hyperoxia on Lung Utrastructure

1970 ◽  
Vol 28 ◽  
pp. 26-27
Author(s):  
Gladys Harrison
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Light Microscopy ◽  
Oxygen Effects ◽  
Age Dependent ◽  
The Central Nervous System ◽  
The Subject ◽  
Space Age ◽  
Alveolar Septa ◽  
Extensive Damage

With the advent of the space age and the need to determine the requirements for a space cabin atmosphere, oxygen effects came into increased importance, even though these effects have been the subject of continuous research for many years. In fact, Priestly initiated oxygen research when in 1775 he published his results of isolating oxygen and described the effects of breathing it on himself and two mice, the only creatures to have had the “privilege” of breathing this “pure air”.Early studies had demonstrated the central nervous system effects at pressures above one atmosphere. Light microscopy revealed extensive damage to the lungs at one atmosphere. These changes which included perivascular and peribronchial edema, focal hemorrhage, rupture of the alveolar septa, and widespread edema, resulted in death of the animal in less than one week. The severity of the symptoms differed between species and was age dependent, with young animals being more resistant.

Emigration of neutrophils in the central nervous system

1983 ◽  
Vol 41 ◽  
pp. 788-789
Author(s):  
John L.Beggs ◽  
John D. Waggener ◽  
Wanda Miller ◽  
Jane Watkins
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Osmium Tetroxide ◽  
White Blood Cells ◽  
Arterial Perfusion ◽  
E Coli ◽  
Intracisternal Injection ◽  
The Central Nervous System ◽  
Brain And Spinal Cord ◽  
Interendothelial Junctions

Studies using mesenteric and ear chamber preparations have shown that interendothelial junctions provide the route for neutrophil emigration during inflammation. The term emigration refers to the passage of white blood cells across the endothelium from the vascular lumen. Although the precise pathway of transendo- thelial emigration in the central nervous system (CNS) has not been resolved, the presence of different physiological and morphological (tight junctions) properties of CNS endothelium may dictate alternate emigration pathways.To study neutrophil emigration in the CNS, we induced meningitis in guinea pigs by intracisternal injection of E. coli bacteria.In this model, leptomeningeal inflammation is well developed by 3 hr. After 3 1/2 hr, animals were sacrificed by arterial perfusion with 3% phosphate buffered glutaraldehyde. Tissues from brain and spinal cord were post-fixed in 1% osmium tetroxide, dehydrated in alcohols and propylene oxide, and embedded in Epon. Thin serial sections were cut with diamond knives and examined in a Philips 300 electron microscope.

Mammalian Bone Marrow Acetylcholinesterase

1982 ◽  
Vol 40 ◽  
pp. 44-45
Author(s):  
Ezzatollah Keyhani
Keyword(s):  
Central Nervous System ◽  
Bone Marrow ◽  
Nervous System ◽  
Common Property ◽  
Extracellular Medium ◽  
The Central Nervous System ◽  
The Common ◽  
Mammalian Bone

Acetylcholinesterase (EC 3.1.1.7) (ACHE) has been localized at cholinergic junctions both in the central nervous system and at the periphery and it functions in neurotransmission. ACHE was also found in other tissues without involvement in neurotransmission, but exhibiting the common property of transporting water and ions. This communication describes intracellular ACHE in mammalian bone marrow and its secretion into the extracellular medium.

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