scholarly journals Impact of Refeeding on Intestinal Development and Function in Infant Rabbits Subjected to Protein-Energy Malnutrition

1990 ◽  
Vol 27 (3) ◽  
pp. 245-251 ◽  
Author(s):  
J Decker Butzner ◽  
D Grant Gall
Keyword(s):  
Protein Energy Malnutrition ◽  
Intestinal Development ◽  
Protein Energy ◽  
And Function

Left ventricular mass and function in children with severe protein energy malnutrition

1992 ◽  
Vol 35 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Shyam Sunder Kothari ◽  
Tejas M. Patel ◽  
Amulyaratha N. Shetalwad ◽  
Thakorebhai K. Patel
Keyword(s):  
Left Ventricular Mass ◽  
Protein Energy Malnutrition ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
Protein Energy ◽  
And Function

scholarly journals Protein Detection in Clinical Diagnosis and Management of Prevalent Neurodegenerative Diseases and Metabolic Disorders

2021 ◽  
Author(s):  
Ohanube A.K. Goodluck ◽  
Obeta M. Uchejeso ◽  
Ikeagwulonu R. Chinaza
Keyword(s):  
Diabetes Mellitus ◽  
Neurodegenerative Diseases ◽  
Metabolic Disorders ◽  
Protein Energy Malnutrition ◽  
Protein Detection ◽  
Cost Effective ◽  
Structure And Function ◽  
Accurate Diagnosis ◽  
Protein Energy ◽  
And Function

An accurate diagnosis gives leeway to cost-effective treatments. However, many diseases continue to evolve; hence, their etiology is sometimes missed due to the procedures used during diagnosis. Protein-related diseases include proteopathies (proteinopathies) such as neurodegenerative diseases and metabolic disorders like protein-energy malnutrition and some hormonopathies. Hormonopathies are associated with the change in the production of hormones. Diabetes mellitus, a type of hormonopathy, is reviewed in this work alongside neurodegenerative diseases and protein-energy malnutrition. This chapter aims to elucidate more on the diagnosis of these diseases considering the structure and function of their proteins viz-a-viz their deficiencies and hyper-production in man. Their pathogenesis and the principles underlying their diagnosis are further discussed to optimize the management of these diseases among patients.

Luminal factors stimulate intestinal repair during the refeeding of malnourished infant rabbits

1993 ◽  
Vol 71 (9) ◽  
pp. 650-656 ◽  
Author(s):  
D. J. Philpott ◽  
D. R. Kirk ◽  
J. D. Butzner
Keyword(s):  
Intestinal Adaptation ◽  
Protein Energy Malnutrition ◽  
Distal Segment ◽  
Dietary Control ◽  
Distal Intestine ◽  
Protein Energy ◽  
Systemic Factors ◽  
Mucosal Mass ◽  
And Function ◽  
Malnourished Group

We examined the role of luminal versus systemic factors in promoting intestinal recovery during the refeeding of previously malnourished infant rabbits. Malnutrition was induced by litter expansion at 7 days of age. A 20-cm Thiry–Vella (T-V) loop was created in the intestine of each malnourished and dietary control animal at 21 days of age. Beginning on day 28, controls and one half of the malnourished group (malnourished–refed) were fed chow ad libitum, whereas the remainder of the malnourished group received half the amount of chow given to the malnourished–refed group. On day 35, proximal and distal segments from the intact intestine that remained in continuity as well as segments from the excluded T-V loops were examined. Malnutrition severely reduced mucosal mass and disaccharidase activities in the intact distal intestine. A brief period of refeeding led to a rapid recovery of these parameters. In contrast, the excluded T-V loop segments of the control, malnourished, and malnourished–refed groups all displayed decreased mucosal mass and impaired function to a degree similar to that observed in the intact distal segment from the malnourished group. These results indicate that luminal factors are essential for (i) the maintenance of normal intestinal structure and function in infant rabbits and (ii) the promotion of mucosal repair following nutritional rehabilitation of malnourished animals.Key words: protein-energy malnutrition, intestinal adaptation, Thiry–Vella loop, refeeding.

IMPROVEMENT THE PROPERTIES OF YOGHURT USING LEGUMES TO THERAPY PROTEIN ENERGY MALNUTRITION

2018 ◽  
Vol 3 (5) ◽  
pp. 79-88
Author(s):  
Abtsam M.F. Badr ◽  
D.A.M. Amer ◽  
M.Y.A. El- Hawary ◽  
A.M.A. Naem
Keyword(s):  
Protein Energy Malnutrition ◽  
Protein Energy

scholarly journals Sarcopenic Obesity in Liver Cirrhosis: Possible Mechanism and Clinical Impact

2021 ◽  
Vol 22 (4) ◽  
pp. 1917
Author(s):  
Hiroki Nishikawa ◽  
Hirayuki Enomoto ◽  
Shuhei Nishiguchi ◽  
Hiroko Iijima
Keyword(s):  
Liver Cirrhosis ◽  
Current Knowledge ◽  
Protein Energy Malnutrition ◽  
Public Health Problem ◽  
Diagnostic Value ◽  
Sarcopenic Obesity ◽  
Important Public Health Problem ◽  
Alcoholic Fatty Liver ◽  
Protein Energy ◽  
Clinical Consequences

The picture of chronic liver diseases (CLDs) has changed considerably in recent years. One of them is the increase of non-alcoholic fatty liver disease. More and more CLD patients, even those with liver cirrhosis (LC), tend to be presenting with obesity these days. The annual rate of muscle loss increases with worsening liver reserve, and thus LC patients are more likely to complicate with sarcopenia. LC is also characterized by protein-energy malnutrition (PEM). Since the PEM in LC can be invariable, the patients probably present with sarcopenic obesity (Sa-O), which involves both sarcopenia and obesity. Currently, there is no mention of Sa-O in the guidelines; however, the rapidly increasing prevalence and poorer clinical consequences of Sa-O are recognized as an important public health problem, and the diagnostic value of Sa-O is expected to increase in the future. Sa-O involves a complex interplay of physiological mechanisms, including increased inflammatory cytokines, oxidative stress, insulin resistance, hormonal disorders, and decline of physical activity. The pathogenesis of Sa-O in LC is diverse, with a lot of perturbations in the muscle–liver–adipose tissue axis. Here, we overview the current knowledge of Sa-O, especially focusing on LC.

scholarly journals Dynamic Oral Texture Properties of Selected Indigenous Complementary Porridges Used in African Communities

Foods ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 221 ◽  
Author(s):  
James Makame ◽  
Tanita Cronje ◽  
Naushad M. Emmambux ◽  
Henriette De Kock
Keyword(s):  
Young Children ◽  
Low Income ◽  
Nutrient Intake ◽  
Control Method ◽  
Protein Energy Malnutrition ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Texture Properties ◽  
Protein Energy ◽  
Infants And Young Children

Child malnutrition remains a major public health problem in low-income African communities, caused by factors including the low nutritional value of indigenous/local complementary porridges (CP) fed to infants and young children. Most African children subsist on locally available starchy foods, whose oral texture is not well-characterized in relation to their sensorimotor readiness. The sensory quality of CP affects oral processing (OP) abilities in infants and young children. Unsuitable oral texture limits nutrient intake, leading to protein-energy malnutrition. The perception of the oral texture of selected African CPs (n = 13, Maize, Sorghum, Cassava, Orange-fleshed sweet potato (OFSP), Cowpea, and Bambara) was investigated by a trained temporal-check-all-that-apply (TCATA) panel (n = 10), alongside selected commercial porridges (n = 19). A simulated OP method (Up-Down mouth movements- munching) and a control method (lateral mouth movements- normal adult-like chewing) were used. TCATA results showed that Maize, Cassava, and Sorghum porridges were initially too thick, sticky, slimy, and pasty, and also at the end not easy to swallow even at low solids content—especially by the Up-Down method. These attributes make CPs difficult to ingest for infants given their limited OP abilities, thus, leading to limited nutrient intake, and this can contribute to malnutrition. Methods to improve the texture properties of indigenous CPs are needed to optimize infant nutrient intake.

scholarly journals Study of NT-pro-BNP and Hs-Troponin I biomarkers for early detection of children’s heart function of protein-energy malnutrition

2019 ◽  
Vol 11 (2) ◽  
Author(s):  
Herlina Dimiati ◽  
Abdus Samik Wahab ◽  
Mohammad Juffrie ◽  
Madarina Julia ◽  
Basri A. Gani
Keyword(s):  
Troponin I ◽  
Heart Function ◽  
Protein Energy Malnutrition ◽  
Area Under The Curve ◽  
Left Ventricular ◽  
The Body ◽  
Chromatography Method ◽  
Blood Electrolytes ◽  
Ventricular Mass ◽  
Protein Energy

The Protein Energy Malnutrition (PEM) is the condition of a lack of carbohydrate and protein stores in the body that trigger chronic failure nutrient intake and body maintenance function caused to impact the heart functions. The NT-pro-BNP and Hs- Troponin I proteins were found as the indicator of cardiac dysfunction. The sixty subjects of PEM, analyzed by standard of Indonesia Healt Ministry as well as nutritional status. The blood electrolytes examined by laboratory assay and the levels of Hs-Troponin 1 and NT-Pro-BNP were analyzed by Immune-Chromatography method. Assessing of the ventricular mass with the seeing the peak of the diastolic flow rate of left ventricular that estimated by the curve of the receiver operating characteristic and the area under the curve (P<0.05). The result has shown that the PEM decreased in the left ventricular mass for impaired heart function and systolic disorder. The Hs- Troponin I (90.9%) has better sensitivity than NT-pro-BNP (85.5%) if the merger of those markers possesses the lowest sensitivity (81.8%). These proteins have good biomarkers in heart function, mainly in cases where PEM is present.

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