A Novel Simulation-Based Approach for Comparing the Population Against Average Bioequivalence Statistical Test for the Evaluation of Nasal Spray Products on Spray Pattern and Droplet Size Distribution Parameters

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Jernej Grmaš ◽  
Vesna Lužar-Stiffler ◽  
Rok Dreu ◽  
Rade Injac
Keyword(s):  
Size Distribution ◽  
Nasal Spray ◽  
Droplet Size ◽  
Droplet Size Distribution ◽  
Statistical Test ◽  
Spray Pattern ◽  
Average Bioequivalence ◽  
Simulation Based ◽  
Distribution Parameters

scholarly journals Experimental Study on Spray Breakup in Turbulent Atomization Using a Spiral Nozzle

Processes ◽  
2019 ◽  
Vol 7 (12) ◽  
pp. 911 ◽  
Author(s):  
Ondřej Krištof ◽  
Pavel Bulejko ◽  
Tomáš Svěrák
Keyword(s):  
Size Distribution ◽  
Droplet Size ◽  
Laser Doppler Anemometry ◽  
Droplet Size Distribution ◽  
Distribution Functions ◽  
Gas Absorption ◽  
Spray Angle ◽  
Archimedean Spiral ◽  
Spray Pattern ◽  
Pressure Impact

Spiral nozzles are widely used in wet scrubbers to form an appropriate spray pattern to capture the polluting gas/particulate matterwith the highest possible efficiency. Despite this fact, and a fact that it is a nozzle with a very atypical spray pattern (a full cone consisting of three concentric hollow cones), very limited amount of studies have been done so far on characterization of this type of nozzle. This work reports preliminary results on the spray characteristics of a spiral nozzle used for gas absorption processes. First, we experimentally measured the pressure impact footprint of the spray generated. Then effective spray angles were evaluated from the photographs of the spray and using the pressure impact footprint records via Archimedean spiral equation. Using the classical photography, areas of primary and secondary atomization were determined together with the droplet size distribution, which were further approximated using selected distribution functions. Radial and tangential spray velocity of droplets were assessed using the laser Doppler anemometry. The results show atypical behavior compared to different types of nozzles. In the investigated measurement range, the droplet-size distribution showed higher droplet diameters (about 1 mm) compared to, for example, air assisted atomizers. It was similar for the radial velocity, which was conversely lower (max velocity of about 8 m/s) compared to, for example, effervescent atomizers, which can produce droplets with a velocity of tens to hundreds m/s. On the contrary, spray angle ranged from 58° and 111° for the inner small and large cone, respectively, to 152° for the upper cone, and in the measured range was independent of the inlet pressure of liquid at the nozzle orifice.

scholarly journals Simultaneous retrieval of aerosol and cloud properties during the MILAGRO field campaign

2011 ◽  
Vol 11 (13) ◽  
pp. 6245-6263 ◽  
Author(s):  
K. Knobelspiesse ◽  
B. Cairns ◽  
J. Redemann ◽  
R. W. Bergstrom ◽  
A. Stohl
Keyword(s):  
Optical Properties ◽  
Size Distribution ◽  
Aerosol Optical Depth ◽  
Optical Depth ◽  
Droplet Size ◽  
Cloud Droplet ◽  
Droplet Size Distribution ◽  
Cloud Droplet Size Distribution ◽  
Distribution Parameters ◽  
Aerosol Properties

Abstract. Estimation of Direct Climate Forcing (DCF) due to aerosols in cloudy areas has historically been a difficult task, mainly because of a lack of appropriate measurements. Recently, passive remote sensing instruments have been developed that have the potential to retrieve both cloud and aerosol properties using polarimetric, multiple view angle, and multi spectral observations, and therefore determine DCF from aerosols above clouds. One such instrument is the Research Scanning Polarimeter (RSP), an airborne prototype of a sensor on the NASA Glory satellite, which unfortunately failed to reach orbit during its launch in March of 2011. In the spring of 2006, the RSP was deployed on an aircraft based in Veracruz, Mexico, as part of the Megacity Initiative: Local and Global Research Observations (MILAGRO) field campaign. On 13 March, the RSP over flew an aerosol layer lofted above a low altitude marine stratocumulus cloud close to shore in the Gulf of Mexico. We investigate the feasibility of retrieving aerosol properties over clouds using these data. Our approach is to first determine cloud droplet size distribution using the angular location of the cloud bow and other features in the polarized reflectance. The selected cloud was then used in a multiple scattering radiative transfer model optimization to determine the aerosol optical properties and fine tune the cloud size distribution. In this scene, we were able to retrieve aerosol optical depth, the fine mode aerosol size distribution parameters and the cloud droplet size distribution parameters to a degree of accuracy required for climate modeling. This required assumptions about the aerosol vertical distribution and the optical properties of the coarse aerosol size mode. A sensitivity study was also performed to place this study in the context of future systematic scanning polarimeter observations, which found that the aerosol complex refractive index can also be observed accurately if the aerosol optical depth is larger than roughly 0.8 at a wavelength of (0.555 μm).

MODELING DROPLET SIZE DISTRIBUTION NEAR A NOZZLE OUTLET IN AN ICING WIND TUNNEL

2006 ◽  
Vol 16 (6) ◽  
pp. 673-686 ◽  
Author(s):  
Laszlo E. Kollar ◽  
Masoud Farzaneh ◽  
Anatolij R. Karev
Keyword(s):  
Wind Tunnel ◽  
Size Distribution ◽  
Droplet Size ◽  
Droplet Size Distribution ◽  
Nozzle Outlet

CFD simulation of ultrasonic atomization pyrolysis reactor: the influence of droplet behaviors and solvent evaporation

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jian Wang ◽  
Jichuan Wu ◽  
Shouqi Yuan ◽  
Wei-Cheng Yan
Keyword(s):  
Flow Pattern ◽  
Size Distribution ◽  
Droplet Size ◽  
Cfd Simulation ◽  
Collection Efficiency ◽  
Great Influence ◽  
Droplet Size Distribution ◽  
Solvent Evaporation ◽  
Droplet Collision ◽  
Ultrasonic Atomization

Abstract Previous work showed that particle behaviors in ultrasonic atomization pyrolysis (UAP) reactor have a great influence on the transport and collection of particles. In this study, the effects of droplet behaviors (i.e. droplet collision and breakage) and solvent evaporation on the droplet size, flow field and collection efficiency during the preparation of ZnO particles by UAP were investigated. The collision, breakage and solvent evaporation conditions which affect the droplet size distribution and flow pattern were considered in CFD simulation based on Eulerian-Lagrangian method. The results showed that droplet collision and breakage would increase the droplet size, broaden the droplet size distribution and hinder the transport of droplets. Solvent evaporation obviously changed the flow pattern of droplets. In addition, both droplet behaviors and solvent evaporation reduced the collection efficiency. This study could provide detail information for better understanding the effect of droplet behaviors and solvent evaporation on the particle production process via UAP reactor.

Predicting Droplet Size Distribution by Image Processing Technique for an Air Blast Atomizer

2014 ◽  
Vol 32 (14) ◽  
pp. 1655-1663 ◽  
Author(s):  
Leila Kavoshi ◽  
Mohammad S. Hatamipour ◽  
Amir Rahimi ◽  
Mehdi Momeni
Keyword(s):  
Image Processing ◽  
Size Distribution ◽  
Droplet Size ◽  
Droplet Size Distribution ◽  
Processing Technique ◽  
Image Processing Technique ◽  
Air Blast

scholarly journals Remote sensing of water cloud droplet size distributions using the backscatter glory: a case study

2004 ◽  
Vol 4 (5) ◽  
pp. 1255-1263 ◽  
Author(s):  
B. Mayer ◽  
M. Schröder ◽  
R. Preusker ◽  
L. Schüller
Keyword(s):  
Remote Sensing ◽  
Size Distribution ◽  
Droplet Size ◽  
Cloud Droplet ◽  
Droplet Size Distribution ◽  
Single Scattering ◽  
Effective Radius ◽  
Radiative Properties ◽  
High Angular Resolution ◽  
Size Distributions

Abstract. Cloud single scattering properties are mainly determined by the effective radius of the droplet size distribution. There are only few exceptions where the shape of the size distribution affects the optical properties, in particular the rainbow and the glory directions of the scattering phase function. Using observations by the Compact Airborne Spectrographic Imager (CASI) in 180° backscatter geometry, we found that high angular resolution aircraft observations of the glory provide unique new information which is not available from traditional remote sensing techniques: Using only one single wavelength, 753nm, we were able to determine not only optical thickness and effective radius, but also the width of the size distribution at cloud top. Applying this novel technique to the ACE-2 CLOUDYCOLUMN experiment, we found that the size distributions were much narrower than usually assumed in radiation calculations which is in agreement with in-situ observations during this campaign. While the shape of the size distribution has only little relevance for the radiative properties of clouds, it is extremely important for understanding their formation and evolution.

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