scholarly journals Lipid Peroxidation Is Associated with the Severity of Periodontal Disease and Local Inflammatory Markers in Patients with Type 2 Diabetes

2012 ◽  
Vol 97 (8) ◽  
pp. E1353-E1362 ◽  
Author(s):  
Alliny S. Bastos ◽  
Dana T. Graves ◽  
Ana Paula de Melo Loureiro ◽  
Carlos Rossa Júnior ◽  
Dulcinéia Saes Parra Abdalla ◽  
...  
Author(s):  
Natasha Z. Anita ◽  
Julia Zebarth ◽  
Brian Chan ◽  
Che-Yuan Wu ◽  
Taha Syed ◽  
...  

2014 ◽  
Vol 2 (1) ◽  
pp. e000030 ◽  
Author(s):  
Mark Hamer ◽  
Ruth A Hackett ◽  
Sophie Bostock ◽  
Antonio I Lazzarino ◽  
Livia A Carvalho ◽  
...  

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Tuula Saukkonen ◽  
Shivaprakash Jagalur Mutt ◽  
Jari Jokelainen ◽  
Anna-Maria Saukkonen ◽  
Ghulam Shere Raza ◽  
...  

2016 ◽  
Vol 06 (01) ◽  
Author(s):  
Siomos K ◽  
Papadakis E ◽  
Tsamardinos I ◽  
Kerkentzes K ◽  
Koygioylis v ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3377
Author(s):  
Omorogieva Ojo ◽  
Xiao-Hua Wang ◽  
Osarhumwese Osaretin Ojo ◽  
Amanda Rodrigues Amorim Adegboye

The use of nutritional interventions for managing diabetes is one of the effective strategies aimed at reducing the global prevalence of the condition, which is on the rise. Almonds are the most consumed tree nut and they are known to be rich sources of protein, monounsaturated fatty acids, essential minerals, and dietary fibre. Therefore, the aim of this review was to evaluate the effects of almonds on gut microbiota, glycometabolism, and inflammatory parameters in patients with type 2 diabetes. Methods: This systematic review and meta-analysis was carried out according to the preferred reporting items for systematic review and meta-analysis (PRISMA). EBSCOhost, which encompasses the Health Sciences Research Databases; Google Scholar; EMBASE; and the reference lists of articles were searched based on population, intervention, control, outcome, and study (PICOS) framework. Searches were carried out from database inception until 1 August 2021 based on medical subject headings (MesH) and synonyms. The meta-analysis was carried out with the Review Manager (RevMan) 5.3 software. Results: Nine randomised studies were included in the systematic review and eight were used for the meta-analysis. The results would suggest that almond-based diets have significant effects in promoting the growth of short-chain fatty acid (SCFA)-producing gut microbiota. Furthermore, the meta-analysis showed that almond-based diets were effective in significantly lowering (p < 0.05) glycated haemoglobin (HbA1c) levels and body mass index (BMI) in patients with type 2 diabetes. However, it was also found that the effects of almonds were not significant (p > 0.05) in relation to fasting blood glucose, 2 h postprandial blood glucose, inflammatory markers (C-reactive protein and Tumour necrosis factor α, TNF-α), glucagon-like peptide-1 (GLP-1), homeostatic model assessment of insulin resistance (HOMA–IR), and fasting insulin. The biological mechanisms responsible for the outcomes observed in this review in relation to reduction in HbA1c and BMI may be based on the nutrient composition of almonds and the biological effects, including the high fibre content and the low glycaemic index profile. Conclusion: The findings of this systematic review and meta-analysis have shown that almond-based diets may be effective in promoting short-chain fatty acid-producing bacteria and lowering glycated haemoglobin and body mass index in patients with type 2 diabetes compared with control. However, the effects of almonds were not significant (p > 0.05) with respect to fasting blood glucose, 2 h postprandial blood glucose, inflammatory markers (C-reactive protein and TNF-α), GLP-1, HOMA–IR, and fasting insulin.


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