Fatty acid-induced increase in serum dialyzable free thyroxine after physical exercise: implication for nonthyroidal illness.

1992 ◽  
Vol 74 (6) ◽  
pp. 1361-1365 ◽  
Author(s):  
K Liewendahl ◽  
T Helenius ◽  
H Näveri ◽  
H Tikkanen
Keyword(s):  
Fatty Acid ◽  
Physical Exercise ◽  
Free Thyroxine ◽  
Nonthyroidal Illness

Free thyroxine assessed with three assays in sera of patients with nonthyroidal illness and of subjects with abnormal concentrations of thyroxine-binding proteins

1993 ◽  
Vol 39 (8) ◽  
pp. 1668-1674 ◽  
Author(s):  
R Docter ◽  
H van Toor ◽  
E P Krenning ◽  
M de Jong ◽  
G Hennemann
Keyword(s):  
Blood Donors ◽  
Reference Range ◽  
Equilibrium Dialysis ◽  
Free Thyroxine ◽  
Serum Samples ◽  
Nonthyroidal Illness ◽  
Nonesterified Fatty Acids ◽  
Thyroxine Binding Globulin ◽  
Control Value ◽  
The Mean

Abstract Three methods for estimating free thyroxine (FT4) in serum were studied: equilibrium dialysis, the SPAC-ET FT4 radioimmunoassay kit, and the Amerlite MAB FT4 luminometric assay. Serum samples from 10 subjects with above-normal thyroxine-binding globulin (TBG), 6 with low TBG, 30 with familial dysalbuminemic hyperthyroxinemia (FDH), 13 with nonesterified fatty acids (NEFA) concentrations in serum > 1.0 mmol/L, and 178 patients with various degrees of nonthyroidal illness (NTI) were measured and compared with samples from 42 euthyroid blood donors. The Amerlite MAB FT4 assay compared well with equilibrium dialysis, whereas the SPAC-ET assay averaged 40% lower. All three assays were not influenced by changes in TBG and showed no or only little changes in the presence of NEFA. Mean FT4 values in the FDH samples were somewhat higher than in controls when measured with the SPAC-ET assay, about equal with equilibrium dialysis, and somewhat below the mean control value with the Amerlite MAB FT4 assay, although individual results were within the control reference range. In NTI patients, no FT4 values were below the control reference range by the Amerlite MAB FT4 assay, 4 of 178 were below this range by equilibrium dialysis, and 1 of 178 was below this range by the SPAC-ET assay. In all assays a large proportion of the NTI samples showed FT4 values above the control reference range, a result that will interfere with the efficacy of these assays for assessing thyroid function in NTI patients.

scholarly journals Metabolism of fatty acids, secondary complications and effects of physical exercise: integrative review

2020 ◽  
Vol 19 (2) ◽  
pp. 154
Author(s):  
Djeyne Silveira Wagmacker ◽  
Alice Miranda De Oliveira ◽  
Edna Conceição De Oliveira ◽  
Alan Carlos Nery Dos Santos ◽  
Luiz Erlon Araújo Rodrigues ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Physical Exercise ◽  
Fatty Acid Metabolism ◽  
Acid Metabolism ◽  
Spatial Configuration ◽  
Integrative Review ◽  
Metabolic Disturbances ◽  
Secondary Complications ◽  
Positive Effects

Introduction: Diet is a complex set of exposures that frequently interact, and whose cumulative effects influence the results of health. This includes effects on systemic inflammation markers in metabolic disturbances and cardiovascular diseases. Various studies have been presented relating the effect of physical exercise on lipids, however, the results are still controversial. Objective: To describe fatty acid metabolism and the effect of physical exercise on secondary complications. Methods: An integrative review was conducted on topics in the Medline, Pubmed, Web of Science and Scopus databases, published up to the year 2017. Results: Fatty acids, depending on their biochemical characteristics and spatial configuration, have differentiated effect on cardiovascular health, however, studies still present contradictory results about the therapeutic use of certain fatty acids. Physical exercise appears to benefit fatty acid metabolism and attenuate the complications secondary to the intake of certain fatty acids, and potentializes the positive effects of distinct fatty acids. Conclusion: However, variants of physical exercise, such as intensity, duration, time of observation of effects of the results, limit the authors to concluding, with a certain degree of certainty, about the effect of physical exercise on fatty acids and secondary complications, since the studies in the literature continue to be contradictory.Keywords: fatty acids, exercise, inflammation, oxidative stress.

scholarly journals Association Between Serum Levels of Adipocyte Fatty Acid-binding Protein and Free Thyroxine

Medicine ◽  
2015 ◽  
Vol 94 (41) ◽  
pp. e1798 ◽  
Author(s):  
Fen-Yu Tseng ◽  
Pei-Lung Chen ◽  
Yen-Ting Chen ◽  
Yu-Chao Chi ◽  
Shyang-Ron Shih ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Serum Levels ◽  
Free Thyroxine ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

Influence of Polyunsaturated Fatty Acid Diet on the Hemorrheological Response to Physical Exercise in Hypoxia*

1989 ◽  
Vol 10 (04) ◽  
pp. 286-291 ◽  
Author(s):  
C. Guezennec ◽  
J. Nadaud ◽  
P. Satabin ◽  
F. Leger ◽  
P. Lafargue
Keyword(s):  
Fatty Acid ◽  
Physical Exercise ◽  
Polyunsaturated Fatty Acid ◽  
Acid Diet

scholarly journals Effect of Nutrition and Physical Exercise on Fatty Acid Composition of Adipose Tissue in Rats

1972 ◽  
Vol 30 (2) ◽  
pp. 53-57
Author(s):  
Keisuke Tsuji ◽  
Etsuko Tsuji ◽  
Fukio Ohta ◽  
Sumiko Oshima ◽  
Hideo Suzuki ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Physical Exercise ◽  
Acid Composition

A free fatty acid – free thyroxine relationship in serum

1968 ◽  
Vol 46 (1) ◽  
pp. 119-120 ◽  
Author(s):  
M. W. Radomski ◽  
A. Britton ◽  
E. Schönbaum
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Binding Sites ◽  
Free Thyroxine ◽  
Short Term ◽  
Serum Free Fatty Acid ◽  
Serum Free ◽  
Close Relationship

Serum free fatty acid (FFA) and free thyroxine (T4) levels were measured in six healthy Army volunteers after exercise, and in rats fasted for 24 and 48 h or exposed to 4 °C for 3 and 6 h. A close relationship between FFA and free T4 values was found in humans and rats. It is suggested that this phenomenon may be a displacement of bound T4 from its binding sites by FFA resulting in short-term changes in metabolically available T4.

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