Expression of Estrogen Receptor-β in Human Breast Tumors
1997 ◽
Vol 82
(7)
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pp. 2371-2374
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Keyword(s):
The expression of a recently described novel estrogen receptor, ER-β, was detected in several human breast tumor biopsy samples and several human breast epithelial cell lines using reverse transcription and polymerase chain reaction (RT-PCR) analysis. Cloning and sequencing of the PCR product from a breast tumor confirmed the identity of the sequence with that of the ER-β mRNA previously reported in human testis. The expression of ER-β was not correlated with that of ER-α, and both ER-α positive and ER-α negative cell lines expressed ER-β mRNA. However, some breast tumors and some cell lines coexpress ER-β and ER-α mRNA. Our data support a possible role for ER-β in human breast cancer.
2001 ◽
Vol 67
(3)
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pp. 199-214
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Keyword(s):
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1981 ◽
Vol 3
(1)
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pp. 61-73
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1996 ◽
Vol 58
(1)
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pp. 21-30
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2008 ◽
Vol 118
(2)
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pp. 293-305
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2010 ◽
Vol 24
(5)
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pp. 501-510
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