Cognitive status and quality of life after treatment for primary CNS lymphoma

Neurology ◽  
2004 ◽  
Vol 62 (4) ◽  
pp. 544-547 ◽  
Author(s):  
H. Harder ◽  
H. Holtel ◽  
J. E.C. Bromberg ◽  
P. Poortmans ◽  
H. Haaxma-Reiche ◽  
...  
Neurology ◽  
2013 ◽  
Vol 81 (1) ◽  
pp. 84-92 ◽  
Author(s):  
N. D. Doolittle ◽  
A. Korfel ◽  
M. A. Lubow ◽  
E. Schorb ◽  
U. Schlegel ◽  
...  

2018 ◽  
Vol 19 (8) ◽  
pp. e407-e418 ◽  
Author(s):  
Matthijs van der Meulen ◽  
Linda Dirven ◽  
Esther J J Habets ◽  
Martin J van den Bent ◽  
Martin J B Taphoorn ◽  
...  

2017 ◽  
Vol 143 (9) ◽  
pp. 1815-1821 ◽  
Author(s):  
Ulrich Herrlinger ◽  
Niklas Schäfer ◽  
Rolf Fimmers ◽  
Frank Griesinger ◽  
Michael Rauch ◽  
...  

2015 ◽  
Vol 156 (12) ◽  
pp. 472-478 ◽  
Author(s):  
Péter Kincses ◽  
Norbert Kovács ◽  
Kázmér Karádi ◽  
János Kállai

This paper is a summary report on the basic questions of the biopsychosocial approach to Parkinson’s disease. It deals with cognitive, affective and psychological health issues which significantly influence the outcome of the physical rehabilitation. In spite of the unchanged cognitive status, the psychological burden of the changes in the quality of life, the obstruction, the change in the affective tone, and the shrinking ability to fulfil social roles decrease the patient’s quality of life. An interdisciplinary approach is best suited for mitigating these effects. Not only the patient but also his/her family and environment is seriously affected by the disease and its consequences. Treatment and rehabilitation options for increasing or maintaining the quality of life of the affected patients are diverse, and significantly depend on the features of the health care system. The authors believe that the following review emphasizing health psychological principles may contribute to the work of professionals working in clinical and rehabilitational fields and through them may increase the quality of life of patients and their family. Orv. Hetil., 2015, 156(12), 472–478.


Author(s):  
Michelle Bourgeois ◽  
Jennifer Brush

Purpose This study evaluated the effects of an intergenerational Montessori after-school program on the engagement, affect, and quality of life of older adults with memory concerns and on the attitudes of children toward older adults. Method Eleven older adults were paired with 11 children to participate in a 45-min after-school activity program. Observations of engagement and affect during the interactions were collected 3 times a week for 4 weeks. The older adults' engagement and affect also were observed during 45-min planning/discussion sessions without the children present before their arrival to the program. Results Results revealed significant differences in older adults' engagement and positive affect when the children were present. Significant pre–post improvements in reported quality of life and maintenance of cognitive status were associated with program participation. Children demonstrated more active than passive engagement and more happy than neutral affect during activity sessions. Four of the seven children improved their positive ratings of older adults. Conclusions This program documented success in improving engagement and affect in older adults with mild memory concerns while engaging with children. Future studies with a larger sample of participants with varying degrees of memory impairment are needed to investigate the potential of this promising program.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S36-S36 ◽  
Author(s):  
Annica Backman ◽  
Anders Sköldunger

Abstract A critical challenge facing aged care systems throughout the world is to meet the complex care needs of a growing population of older persons. Although person-centred care has been advocated as the “gold standard” and a key component of high quality of care, the significance of care utilization in person-centred units as well as the impact of person-centred care on resident quality of life and staff job strain in nursing home care is yet to be explored. Thus, the aim was to explore person-centred care and its association to resource use, resident quality of life and staff job strain. The study is based on a cross-sectional national survey and data on 4831 residents and 3605 staff were collected by staff in 2014, deriving from nursing homes in 35 Swedish municipalities. In this study, descriptive statistics and regression modelling were used to explore this association. The preliminary results showed that person-centred care was positively associated to resource use (i.e care hours) and resident quality of life in Swedish nursing homes, when controlling for resident age, gender and cognitive status. Person-centred care was negatively associated to staff perception of job strain. This indicates that person-centred care provision seem to increase resource use (i.e. slightly more care hours utilized) but also beneficially impact resident quality of life as well as alleviate care burden in terms job strain among staff.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S906-S906
Author(s):  
Wilma E Afunugo ◽  
Rafael Samper-Ternent

Abstract According to the Alzheimer’s Association, 5.6 million Americans age 65 and older are living with Alzheimer’s Disease. Since pharmacological treatments have yet to be developed, we want to determine whether the amount and quality of social support influence the quality of life (QoL) of persons with dementia so they can lead active and purposeful lives. We analyzed data from 22,030 individuals aged 50+ from the 2010 Health and Retirement Study cohort. The dependent variable, QoL, was measured as self-rated health. The main independent variable, cognitive status, was obtained through direct and proxy interview measurements of cognition. For social support, a composite score including the number of social contacts/close relationships and perceived social support/strain was created. Lastly, several covariates were included. Longitudinally, we examined how QoL changed between 2010 and 2012 using 3 stepwise regression models. Model 1 found those with normal cognition have lower odds of poor QoL vs. those with cognitive impairment (OR = 0.38, p <.0001), number of relationships and perceived social support decreases the odds of poor QoL (p = 0.003, p <.0001), while social strain increases the odds of poor QoL (p <.0001). Model 3 revealed similar findings but also, persons with comorbidities have increased odds of poor QoL (p <.0001), while persons with better function have decreased odds of poor QoL (p <.0001). In conclusion, these results can be used to design interventions to improve social support and reduce social strain, which can also improve QoL for dementia caregivers.


2011 ◽  
Vol 17 (8) ◽  
pp. 991-1001 ◽  
Author(s):  
F Patti ◽  
MP Amato ◽  
M Trojano ◽  
S Bastianello ◽  
MR Tola ◽  
...  

Background: The precise relationships among quality of life, depression, fatigue and cognitive impairment in multiple sclerosis (MS) are complex and poorly understood. Objective: To assess the effects of subcutaneous interferon beta-1a on quality of life, depression and fatigue over 3 years in the COGIMUS study, and to examine the relationship between these outcomes and baseline cognitive status. Methods: COGIMUS was an observational 3-year trial assessing cognitive function in 459 patients with relapsing–remitting MS treated with subcutaneous interferon beta-1a. Results: In total, 331 patients completed the study (168 received interferon beta-1a, 44 µg subcutaneously three times weekly, and 163 received interferon beta-1a, 22 µg subcutaneously three times weekly). Mean MS Quality of Life-54 (MSQoL-54) composite scores did not change over time. There were no significant differences between groups in MSQoL-54 composite scores when patients were grouped by treatment dose and baseline cognitive status. Mean (standard deviation) Hamilton Depression Rating Scale score decreased from 6.8 (4.9) at baseline to 5.8 (5.9) at year 3. Mean total Fatigue Impact Scale scores were low (<30) at all time points. Conclusion: Quality of life, depression and fatigue remained largely stable over 3 years; no effects of treatment dose or baseline cognitive status were found.


10.12737/5911 ◽  
2014 ◽  
Vol 21 (3) ◽  
pp. 104-108
Author(s):  
Молчанова ◽  
Zh. Molchanova

Multiple sclerosis is the most frequent disease of the central nervous system. An increase in multiple sclerosis frequency was registered in several countries including Russia. This may be associated with better multiple sclerosis diagnosis and treatment, better data collection and real increase in multiple sclerosis incidence. Early disability and its rapid progression emphasize the medico-social importance of multiple sclerosis. Neuropsychological disturbances are often observed in multiple sclerosis, being one of the important components in the formation of clinical disease. 43 patients living in the North region with definite multiple sclerosis and mild or moderate disability were tested with expended neuropsychological, neurological and study of quality of life. The purpose of the study was to analyze the role of cognitive, emotional and personal peculiarities at multiple sclerosis on quality of life. To assess quality of life the authors used SF-36. The results of this study of quality of life revealed significant differences in the physical, role and social components depending on the cognitive peculiarities.


Sign in / Sign up

Export Citation Format

Share Document