scholarly journals Retinal determination genes coordinate neuroepithelial specification and neurogenesis modes in theDrosophilaoptic lobe

Development ◽  
2016 ◽  
Vol 143 (13) ◽  
pp. 2431-2442 ◽  
Author(s):  
Holger Apitz ◽  
Iris Salecker
Keyword(s):  
Retinal Determination ◽  
Retinal Determination Genes

scholarly journals Retinal determination genes function along with cell-cell signals to regulate Drosophila eye development

BioEssays ◽  
2011 ◽  
Vol 33 (7) ◽  
pp. 538-546 ◽  
Author(s):  
Nicholas E. Baker ◽  
Lucy C. Firth
Keyword(s):  
Eye Development ◽  
Retinal Determination ◽  
Drosophila Eye ◽  
Retinal Determination Genes ◽  
Cell Cell ◽  
Cell Signals

scholarly journals Conditional knockout of retinal determination genes in differentiating cells inDrosophila

FEBS Journal ◽  
2016 ◽  
Vol 283 (15) ◽  
pp. 2754-2766 ◽  
Author(s):  
Meng Jin ◽  
Aiden Eblimit ◽  
Merlyn Pulikkathara ◽  
Stuart Corr ◽  
Rui Chen ◽  
...  
Keyword(s):  
Conditional Knockout ◽  
Retinal Determination ◽  
Retinal Determination Genes

scholarly journals Retinal determination genes as targets and possible effectors of extracellular signals

2009 ◽  
Vol 327 (2) ◽  
pp. 366-375 ◽  
Author(s):  
Lucy C. Firth ◽  
Nicholas E. Baker
Keyword(s):  
Extracellular Signals ◽  
Retinal Determination ◽  
Retinal Determination Genes

scholarly journals Structure of the Retinal Determination Protein Dachshund Reveals a DNA Binding Motif

Structure ◽  
2002 ◽  
Vol 10 (6) ◽  
pp. 787-795 ◽  
Author(s):  
Seung-Sup Kim ◽  
Rong-guang Zhang ◽  
Steve E. Braunstein ◽  
Andrzej Joachimiak ◽  
Ales Cvekl ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Motif ◽  
Retinal Determination

scholarly journals Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila

2006 ◽  
Vol 297 (2) ◽  
pp. 536-549 ◽  
Author(s):  
Jason Anderson ◽  
Claire L. Salzer ◽  
Justin P. Kumar
Keyword(s):  
Retinal Determination ◽  
Embryonic Head

scholarly journals optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila

2013 ◽  
Vol 381 (1) ◽  
pp. 50-61 ◽  
Author(s):  
Yumei Li ◽  
Yuwei Jiang ◽  
Yiyun Chen ◽  
Umesh Karandikar ◽  
Kristi Hoffman ◽  
...  
Keyword(s):  
Morphogenetic Furrow ◽  
Retinal Determination

scholarly journals Position dependent responses to discontinuities in the retinal determination network

2009 ◽  
Vol 326 (1) ◽  
pp. 121-130 ◽  
Author(s):  
Claire L. Salzer ◽  
Justin P. Kumar
Keyword(s):  
Retinal Determination

scholarly journals Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Stephan Heermann ◽  
Lucas Schütz ◽  
Steffen Lemke ◽  
Kerstin Krieglstein ◽  
Joachim Wittbrodt
Keyword(s):  
Marginal Zone ◽  
Eye Development ◽  
Optic Vesicle ◽  
Basal Surface ◽  
Morphogenetic Protein ◽  
Retinal Determination ◽  
Optic Cup ◽  
Morphological Transformations ◽  
Vertebrate Eye ◽  
Ciliary Marginal Zone

The hemispheric, bi-layered optic cup forms from an oval optic vesicle during early vertebrate eye development through major morphological transformations. The overall basal surface, facing the developing lens, is increasing, while, at the same time, the space basally occupied by individual cells is decreasing. This cannot be explained by the classical view of eye development. Using zebrafish (Danio rerio) as a model, we show that the lens-averted epithelium functions as a reservoir that contributes to the growing neuroretina through epithelial flow around the distal rims of the optic cup. We propose that this flow couples morphogenesis and retinal determination. Our 4D data indicate that future stem cells flow from their origin in the lens-averted domain of the optic vesicle to their destination in the ciliary marginal zone. BMP-mediated inhibition of the flow results in ectopic neuroretina in the RPE domain. Ultimately the ventral fissure fails to close resulting in coloboma.

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