A Predictive Model Using Histopathologic Characteristics of Early-Stage Type 1 Endometrial Cancer to Identify Patients at High Risk for Lymph Node Metastasis

2015 ◽  
Vol 22 (13) ◽  
pp. 4224-4232 ◽  
Author(s):  
Sofiane Bendifallah ◽  
Geoffroy Canlorbe ◽  
Enora Laas ◽  
Florence Huguet ◽  
Charles Coutant ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Lymph Node Metastasis ◽  
Predictive Model ◽  
Early Stage ◽  
Node Metastasis

scholarly journals Predictors of Survival in Women with High-Risk Endometrial Cancer and Comparisons of Sandwich versus Concurrent Adjuvant Chemotherapy and Radiotherapy

2020 ◽  
Vol 17 (16) ◽  
pp. 5941
Author(s):  
Hui-Hua Chen ◽  
Wan-Hua Ting ◽  
Hsu-Dong Sun ◽  
Ming-Chow Wei ◽  
Ho-Hsiung Lin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Endometrial Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Body Mass ◽  
Paraaortic Lymph Node ◽  
Node Metastasis ◽  
Paraaortic Lymph Node Metastasis

Background: to elucidate the predictors of progression-free survival (PFS) and overall survival (OS) in high-risk endometrial cancer patients. Methods: the medical records of all consecutivewomen with high-risk endometrial cancer were reviewed. Results: among 92 high-risk endometrial cancer patients, 30 women experienced recurrence, and 21 women died. The 5-year PFS and OS probabilities were 65.3% and 75.9%, respectively. Multivariable Cox regression revealed that body mass index (hazard ratio (HR) = 1.11), paraaortic lymph node metastasis (HR = 11.11), lymphovascular space invasion (HR = 5.61), and sandwich chemoradiotherapy (HR = 0.15) were independently predictors of PFS. Body mass index (HR = 1.31), paraaortic lymph node metastasis (HR = 32.74), non-endometrioid cell type (HR = 11.31), and sandwich chemoradiotherapy (HR = 0.07) were independently predictors of OS. Among 51 women who underwent sandwich (n = 35) or concurrent (n = 16) chemoradiotherapy, the use of sandwich chemoradiotherapy were associated with better PFS (adjusted HR = 0.26, 95% CI = 0.08–0.87, p = 0.03) and OS (adjusted HR = 0.11, 95% CI = 0.02–0.71, p = 0.02) compared with concurrent chemoradiotherapy. Conclusion: compared with concurrent chemoradiotherapy, sandwich chemoradiotherapy was associated with better PFS and OS in high-risk endometrial cancer patients. In addition, high body mass index, paraaortic lymph node metastasis, and non-endometrioid cell type were also predictors of poor OS in high-risk endometrial cancer patients.

scholarly journals DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer

2015 ◽  
Vol 112 (10) ◽  
pp. 1656-1664 ◽  
Author(s):  
T S Njølstad ◽  
◽  
J Trovik ◽  
T S Hveem ◽  
M L Kjæreng ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Lymph Node Metastasis ◽  
Dna Ploidy ◽  
High Risk Patients ◽  
Node Metastasis ◽  
Risk Patients

Tumor size is an independent predictor of lymph node metastasis and survival in early stage endometrioid endometrial cancer

2014 ◽  
Vol 292 (1) ◽  
pp. 183-190 ◽  
Author(s):  
Haider Mahdi ◽  
Adnan R. Munkarah ◽  
Rouba Ali-Fehmi ◽  
Jessica Woessner ◽  
Shetal N. Shah ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Tumor Size ◽  
Independent Predictor ◽  
Early Stage ◽  
Node Metastasis ◽  
Endometrioid Endometrial Cancer

scholarly journals Utility of PET/CT to Evaluate Retroperitoneal Lymph Node Metastasis in High-Risk Endometrial Cancer: Results of ACRIN 6671/GOG 0233 Trial

Radiology ◽  
2017 ◽  
Vol 283 (2) ◽  
pp. 450-459 ◽  
Author(s):  
Mostafa Atri ◽  
Zheng Zhang ◽  
Farrokh Dehdashti ◽  
Susanna I. Lee ◽  
Helga Marques ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Lymph Node Metastasis ◽  
Retroperitoneal Lymph Node ◽  
Node Metastasis ◽  
Pet Ct
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