scholarly journals Drug Transcellular Transport Assay Using a High Porosity Honeycomb Film

2021 ◽  
Vol 44 (5) ◽  
pp. 635-641
Author(s):  
Yuya Nakazono ◽  
Hiroshi Arakawa ◽  
Masafumi Nishino ◽  
Ikumi Yamaki ◽  
Takahiro Oba ◽  
...  
Keyword(s):  
High Porosity ◽  
Transcellular Transport ◽  
Transport Assay

scholarly journals Usefulness of A Model-Based Approach for Estimating In Vitro P-Glycoprotein Inhibition Potency in a Transcellular Transport Assay

2016 ◽  
Vol 105 (2) ◽  
pp. 891-896 ◽  
Author(s):  
Wataru Kishimoto ◽  
Naoki Ishiguro ◽  
Eva Ludwig-Schwellinger ◽  
Thomas Ebner ◽  
Kazuya Maeda ◽  
...  
Keyword(s):  
Transcellular Transport ◽  
Model Based ◽  
P Glycoprotein ◽  
Transport Assay ◽  
Inhibition Potency ◽  
Glycoprotein Inhibition

Microscopy of porous ceramics

1989 ◽  
Vol 47 ◽  
pp. 438-439
Author(s):  
H. M. Kerch ◽  
R. A. Gerhardt
Keyword(s):  
Porous Ceramics ◽  
Specimen Preparation ◽  
High Porosity ◽  
Ion Milling ◽  
Forming Process ◽  
Preparation Methods ◽  
Pore Texture ◽  
Proper Design ◽  
And Function ◽  
Function Information

Highly porous ceramics are employed in a variety of engineering applications due to their unique mechanical, optical, and electrical characteristics. In order to achieve proper design and function, information about the pore structure must be obtained. Parameters of importance include pore size, pore volume, and size distribution, as well as pore texture and geometry. A quantitative determination of these features for high porosity materials by a microscopic technique is usually not done because artifacts introduced by either the sample preparation method or the image forming process of the microscope make interpretation difficult.Scanning electron microscopy for both fractured and polished surfaces has been utilized extensively for examining pore structures. However, there is uncertainty in distinguishing between topography and pores for the fractured specimen and sample pullout obscures the true morphology for samples that are polished. In addition, very small pores (nm range) cannot be resolved in the S.E.M. On the other hand, T.E.M. has better resolution but the specimen preparation methods involved such as powder dispersion, ion milling, and chemical etching may incur problems ranging from preferential widening of pores to partial or complete destruction of the pore network.

Controlling porosity and density of nanocellulose aerogels for superhydrophobic light materials

TAPPI Journal ◽  
2018 ◽  
Vol 17 (03) ◽  
pp. 145-153 ◽  
Author(s):  
Chengua Yu ◽  
Feng Wang ◽  
Shiyu Fu ◽  
Lucian Lucia
Keyword(s):  
Contact Angle ◽  
Freeze Drying ◽  
Engine Oil ◽  
High Porosity ◽  
Water Mixture ◽  
Waste Engine Oil ◽  
Hydrophobically Modified ◽  
Static Contact ◽  
Oil Water ◽  
Hydrophobic Material

A very low-density oil-absorbing hydrophobic material was fabricated from cellulose nanofiber aerogels–coated silane substances. Nanocellulose aerogels (NCA) superabsorbents were prepared by freeze drying cellulose nanofibril dispersions at 0.2%, 0.5%, 0.8%, 1.0%, and 1.5% w/w. The NCA were hydrophobically modified with methyltrimethoxysilane. The surface morphology and wettability were characterized by scanning electron microscopy and static contact angle. The aerogels displayed an ultralow density (2.0–16.7 mg·cm-3), high porosity (99.9%–98.9%), and superhydrophobicity as evidenced by the contact angle of ~150° that enabled the aerogels to effectively absorb oil from an oil/water mixture. The absorption capacities of hydrophobic nanocellulose aerogels for waste engine oil and olive oil could be up to 140 g·g-1 and 179.1 g·g-1, respectively.

ANALISA POTENSI MINYAK DAN GAS BUMI DENGAN ATRIBUT SEISMIK PADA BATUAN KARBONAT LAPANGAN *ZEFARA* CEKUNGAN SUMATRA SELATAN

KURVATEK ◽  
2017 ◽  
Vol 1 (2) ◽  
pp. 21-31
Author(s):  
Fatimah Miharno
Keyword(s):  
Instantaneous Frequency ◽  
Carbonate Reservoir ◽  
Control Analysis ◽  
High Porosity ◽  
Hydrocarbon Accumulation ◽  
Seismic Attribute ◽  
Data Set ◽  
Log Data ◽  
Low Amplitude ◽  
Rms Amplitude

ABSTRACT*Zefara* Field formation Baturaja on South Sumatra Basin is a reservoir carbonate and prospective gas. Data used in this research were 3D seismik data, well logs, and geological information. According to geological report known that hidrocarbon traps in research area were limestone lithological layer as stratigraphical trap and faulted anticline as structural trap. The study restricted in effort to make a hydrocarbon accumulation and a potential carbonate reservoir area maps with seismic attribute. All of the data used in this study are 3D seismic data set, well-log data and check-shot data. The result of the analysis are compared to the result derived from log data calculation as a control analysis. Hydrocarbon prospect area generated from seismic attribute and are divided into three compartments. The seismic attribute analysis using RMS amplitude method and instantaneous frequency is very effective to determine hydrocarbon accumulation in *Zefara* field, because low amplitude from Baturaja reservoir. Low amplitude hints low AI, determined high porosity and high hydrocarbon contact (HC).  Keyword: Baturaja Formation, RMS amplitude seismic attribute, instantaneous frequency seismic attribute

Energy saving technology for sintering of black bricks from high-siliceous clay

MRS Advances ◽  
2020 ◽  
Vol 5 (61) ◽  
pp. 3123-3131
Author(s):  
Mario Flores Nicolas ◽  
Marina Vlasova ◽  
Pedro Antonio Márquez Aguilar ◽  
Mykola Kakazey ◽  
Marcos Mauricio Chávez Cano ◽  
...  
Keyword(s):  
Low Temperature ◽  
Oxygen Deficiency ◽  
Glass Ceramics ◽  
Total Content ◽  
Ceramic Materials ◽  
Ternary Mixtures ◽  
High Porosity ◽  
Reducing Conditions ◽  
Binary And Ternary Mixtures ◽  
Dark Color

AbstractThe low-temperature synthesis of bricks prepared from high-siliceous clays by the method of plastic molding of blanks was used. For the preparation of brick blanks, binary and ternary mixtures of high-siliceous clays, black sand, and bottle glass cullet were used. Gray-black low-porosity and high-porosity ceramics was obtained by sintering under conditions of oxygen deficiency. It has been established that to initiate plastic in mixtures containing high-siliceous clay, it is necessary to add montmorillonite/bentonite additives, carry out low-temperature sintering, and introduce low-melting glass additives with a melting point ranging from 750 to 800 °C. The performed investigations have shown that the sintering of mixtures with a total content of iron oxide of about 5 wt% under reducing conditions at Tsint. = 800°C for 8 h leads to the formation of glass ceramics consisting of quartz, feldspars, and a phase. The main sources of the appearance of a dark color is the formation of [Fe3+O4]4- and [Fe3+O6]9- anions in the composition of the glass phase and feldspars. By changing the contents of clay, sand, and glass in sintering, it is possible to obtain two types of ceramic materials: (a) in the form of building bricks and (b) in the form of porous fillers.

Enhanced Hydrolytic Stability of Porous Boron Nitride via the Control of Crystallinity, Porosity and Chemical Composition

2018 ◽  
Author(s):  
Ravi Shankar ◽  
Sofia Marchesini ◽  
Camille Petit
Keyword(s):  
Boron Nitride ◽  
Hydrolytic Stability ◽  
Chemical Properties ◽  
Spectroscopic Techniques ◽  
High Porosity ◽  
Heat Treated Sample ◽  
Heat Treated ◽  
Treated Sample ◽  
Molecular Separations ◽  
High Degree

Porous boron nitride is gaining significant attention for applications in molecular separations, photocatalysis, and drug delivery. All these areas call for a high degree of stability (or a controlled stability) over a range of chemical environments, and particularly under humid conditions. The hydrolytic stability of the various forms of boron nitride, including porous boron nitride, has been sparingly addressed in the literature. Here, we map the physical-chemical properties of the material to its hydrolytic stability for a range of conditions. Using analytical, imaging and spectroscopic techniques, we identify the links between the hydrolytic instability of porous boron nitride and its limited crystallinity, high porosity as well as the presence of oxygen atoms. To address this instability issue, we demonstrate that subjecting the material to a thermal treatment leads to the formation of crystalline domains of h-BN exhibiting a hydrophobic character. The heat-treated sample exhibits enhanced hydrolytic stability, while maintaining a high porosity. This work provides an effective and simple approach to producing stable porous boron nitride structures, and will progress the implementation of the material in applications involving interfacial phenomena.<br>

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