Prolonged Recovery Times Improve Acute Postural Control Outcomes in Mice with Surgically Sprained Ankles.

2015 ◽  
Vol 47 ◽  
pp. 794
Author(s):  
Ashley L. Duncan ◽  
Tricia Hubbard-Turner ◽  
Mike J. Turner ◽  
Erik A. Wikstrom
Keyword(s):  
Postural Control ◽  
Recovery Times ◽  
Prolonged Recovery

scholarly journals ADHD and DIRAS Single Nucleotide Polymorphism as an Indicator of Prolonged Concussion Recovery

CommonHealth ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 94-101
Author(s):  
Taziah Kenney ◽  
Jane McDevitt
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Rare Allele ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Adhd Diagnosis ◽  
Hyperactivity Disorder ◽  
Recovery Times ◽  
Prolonged Recovery ◽  
Concussion Recovery ◽  
And Control

The purpose of this study was to determine the association between the presence of a single nucleotide polymorphism (SNP; rs1412005) within DIRAS2 (i.e., a gene associated with attention-deficit/hyperactivity disorder (ADHD) and prolonged recovery following a sport-related concussion. A case-control study design was implemented, where cases and controls were selected from a cohort of 117 deidentified concussed athletes. Eleven samples from this patient cohort self-reported ADHD diagnosis and were age and sex-matched to 22 participants with no self-reported ADHD diagnoses. The average recovery times were 21.50 + 13.96 days and 15.66 + 8.50 days for the case and control groups, respectively. The authors found that only 13.6% of the individuals without an ADHD diagnosis recovered in > 30 days (p = 0.044). Also, the authors found that 72.7% of the carriers of the T allele (i.e., minor allele) recovered in greater than 30 days (p = 0.213).  Researchers concluded that individuals with ADHD had a higher risk of prolonged concussion recovery lasting greater than 30 days. Also, carrying the rare allele was associated with prolonged recovery, which suggests this SNP could be a potential genetic marker for both prolonged concussion recovery and the presence of ADHD.

scholarly journals Effects of prophylactic antibiotic-treatment on post-surgical recovery following intraperitoneal bio-logger implantation in rainbow trout

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Per Hjelmstedt ◽  
Henrik Sundh ◽  
Jeroen Brijs ◽  
Andreas Ekström ◽  
Kristina Snuttan Sundell ◽  
...  
Keyword(s):  
Heart Rate ◽  
Rainbow Trout ◽  
Prophylactic Treatment ◽  
Prophylactic Antibiotic ◽  
Post Surgery ◽  
Recovery Times ◽  
Prolonged Recovery ◽  
Surgical Recovery ◽  
Prophylactic Antibiotic Treatment ◽  
Freely Moving

AbstractBio-logging devices can provide unique insights on the life of freely moving animals. However, implanting these devices often requires invasive surgery that causes stress and physiological side-effects. While certain medications in connection to surgeries have therapeutic capacity, others may have aversive effects. Here, we hypothesized that the commonly prescribed prophylactic treatment with enrofloxacin would increase the physiological recovery rate and reduce the presence of systemic inflammation following the intraperitoneal implantation of a heart rate bio-logger in rainbow trout (Oncorhynchus mykiss). To assess post-surgical recovery, heart rate was recorded for 21 days in trout with or without enrofloxacin treatment. Contrary to our hypothesis, treated trout exhibited a prolonged recovery time and elevated resting heart rates during the first week of post-surgical recovery compared to untreated trout. In addition, an upregulated mRNA expression of TNFα in treated trout indicate a possible inflammatory response 21 days post-surgery. Interestingly, the experience level of the surgeon was observed to have a long-lasting impact on heart rate. In conclusion, our study showed no favorable effects of enrofloxacin treatment. Our findings highlight the importance of adequate post-surgical recovery times and surgical training with regards to improving the welfare of experimental animals and reliability of research outcomes.

Prolonged Recovery Time Improves Long Term Postural Control Outcomes For Mice With Surgically Sprained Ankles.

2016 ◽  
Vol 48 ◽  
pp. 723
Author(s):  
Ashley L. Duncan ◽  
Tricia H. Turner ◽  
Mike J. Turner ◽  
Erik A. Wikstrom
Keyword(s):  
Postural Control ◽  
Recovery Time ◽  
Prolonged Recovery

Role of carotid sinus and aortic nerves in respiratory control of infant rats

1986 ◽  
Vol 251 (4) ◽  
pp. R811-R817 ◽  
Author(s):  
M. A. Hofer
Keyword(s):  
Airway Obstruction ◽  
Carotid Sinus ◽  
Respiratory Control ◽  
Upper Airway ◽  
Airway Occlusion ◽  
Infant Rats ◽  
Tracheal Pressure ◽  
Recovery Times ◽  
Prolonged Recovery ◽  
Low Amplitude

The roles of carotid sinus (CSN) and aortic depressor nerves (ADN) in the maintenance of rhythmic respiration and in the response to airway occlusion were investigated in 8- to 10-day-old infant rats. Cutting the CSN led to a periodic loss of rhythmic respiration with arrhythmic low-amplitude waveforms, frequent end-expiratory pauses, and occasional apneas observed in unanesthetized unrestrained pups studied in their home cage nests by impedance pneumography. Cutting the ADN alone did not have this effect. Sinoaortic denervation (SAD) in which both nerves were cut, produced a more severe disturbance that was not relieved by tracheostomy, indicating that it was not due to upper airway obstruction. Tracheal pressure recordings from anesthetized SAD infants in response to short periods of external airway obstruction showed reduced respiratory efforts and prolonged recovery times, deficits that may play a role in the mortality previously reported after SAD in infant rats.

scholarly journals A descriptive study of ciguatera fish poisoning in Cook Islands dogs and cats: Treatment and outcome

2020 ◽  
Vol 13 (7) ◽  
pp. 1269-1279
Author(s):  
Michelle J. Gray ◽  
M. Carolyn Gates
Keyword(s):  
Survival Rate ◽  
Prognostic Indicators ◽  
Veterinary Clinic ◽  
Cook Islands ◽  
Ciguatera Fish Poisoning ◽  
Fish Poisoning ◽  
Significant Difference ◽  
Recovery Times ◽  
Prolonged Recovery ◽  
Almost All

Background and Aim: Ciguatera fish poisoning (CFP) is an illness caused by the ingestion of fish containing ciguatoxins. Dogs and cats are susceptible to CFP, but there is little published and much unknown about the condition in these species. This study aimed to document the treatment and outcome of canine and feline cases of CFP, and to look for prognostic indicators. Materials and Methods: Six years of medical records from the Esther Honey Foundation Animal Clinic (the only veterinary clinic in the Cook Islands during the study period) were reviewed to identify cases of CFP. Data relating to treatment and outcome were collected. Results: Two hundred and forty-six cases of CFP were identified, comprising 165 dogs and 81 cats. The treatments most commonly administered to cases were fluid therapy and muscle relaxants. Mannitol was only given to five animals. The survival rate was >90% and almost all mortalities occurred in the first week of hospitalization. Recovery was slow, with hospitalization averaging 12.9 days. There was no significant difference in recovery times between dogs and cats. Prolonged periods of anorexia and recumbency were common in both species. Factors associated with prolonged recovery times included case severity, anorexia, and age (in dogs). Conclusion: This article documented the treatment and outcome of animals afflicted by CFP in the Cook Islands. Therapy for CFP was primarily symptomatic and supportive. The survival rate was high, but recovery was often prolonged. The findings will assist veterinarians in giving prognoses and managing owner expectations.

scholarly journals Conservative Management for Stable High Ankle Injuries in Professional Football Players

2017 ◽  
Vol 10 (1) ◽  
pp. 80-84 ◽  
Author(s):  
Derrick M. Knapik ◽  
Anthony Trem ◽  
Joseph Sheehan ◽  
Michael J. Salata ◽  
James E. Voos
Keyword(s):  
Conservative Management ◽  
American Football ◽  
Ankle Injuries ◽  
Football Players ◽  
Ankle Sprains ◽  
Level Of Evidence ◽  
Flow Restriction ◽  
Recovery Times ◽  
Prolonged Recovery ◽  
Level 3

Context: High ankle “syndesmosis” injuries are common in American football players relative to the general population. At the professional level, syndesmotic sprains represent a challenging and unique injury lacking a standardized rehabilitation protocol during conservative management. Evidence Acquisition: PubMed, Biosis Preview, SPORTDiscus, PEDro, and EMBASE databases were searched using the terms syndesmotic injuries, American football, conservative management, and rehabilitation. Study Design: Clinical review. Level of Evidence: Level 3. Results: When compared with lateral ankle sprains, syndesmosis injuries result in significantly prolonged recovery times and games lost. For stable syndesmotic injuries, conservative management features a brief period of immobilization and protected weightbearing followed by progressive strengthening exercises and running, and athletes can expect to return to competition in 2 to 6 weeks. Further research investigating the efficacy of dry needling and blood flow restriction therapy is necessary to evaluate the benefit of these techniques in the rehabilitation process. Conclusion: Successful conservative management of stable syndesmotic injuries in professional American football athletes requires a thorough understanding of the anatomy, injury mechanisms, diagnosis, and rehabilitation strategies utilized in elite athletes.

Minor Adverse Events

2018 ◽  
pp. 141-145
Author(s):  
Corrie E. Chumpitazi
Keyword(s):  
Adverse Events ◽  
Timely Manner ◽  
Patient Factors ◽  
Relative Likelihood ◽  
Significant Harm ◽  
Recovery Times ◽  
Psychological Harm ◽  
Prolonged Recovery ◽  
And Training

The incidence of sedation-related adverse events depends on the medications administered, the characteristics of the procedure, and preexisting patient factors. Minor adverse sedation-related events may present inconvenience or transient discomfort to the patient and, if recognized and supported in a timely manner by the sedationist, will not usually result in physiologic or psychological harm to the patient. Postprocedure vomiting, transient hypoxemia, mild hypotension, emergence reactions, and prolonged recovery times are examples of minor events. The relative likelihood of events of this type (1 of every 200 sedation episodes) provides significant impetus for effective preparation and training for sedationists to effectively respond to or preempt them. These “minor” events can still progress to more significant harm.

scholarly journals Instantaneous Beam Prediction Scheme Against Link Blockage in mmWave Communications

2021 ◽  
Vol 11 (12) ◽  
pp. 5601
Author(s):  
Adel Aldalbahi ◽  
Farzad Shahabi ◽  
Mohammed Jasim
Keyword(s):  
Short Term Memory ◽  
Operation Mode ◽  
Time Frame ◽  
Access Technology ◽  
Dual Beam ◽  
New Radio ◽  
Prediction Scheme ◽  
Directional Transmission ◽  
Recovery Times ◽  
Prolonged Recovery

Millimeter wave (mmWave) bands formulate the standalone (SA) operation mode in the new radio (NR) access technology of 5G systems. These bands rely on beamforming architectures to aggregate antenna array gains that compensate for dynamic channel fluctuations and propagation impairments. However, beamforming results in directional transmission and reception, thus resulting in beam management challenges, foremost initial access, handover, and beam blockage recovery. Here, beam establishment and maintenance must feature ultra-low latencies in the control and data planes to meet network specifications and standardization. Presently, existing schemes rely on arrays redundancy, multi-connectivity, such as dual-beam and carrier aggregation, and out-of-band information. These schemes still suffer from prolonged recovery times and aggregated power consumption levels. Along these lines, this work proposes a fast beam restoration scheme based on deep learning in SA mmWave networks. Once the primary beam is blocked, it predicts alternative beam directions in the next time frame without any reliance on out-of-band information. The scheme adopts long short-term memory (LSTM) due to the robust memory structure, which uses past best beam observations. The scheme achieves near-instantaneous recovery times, i.e., maintaining communications sessions without resetting beam scanning procedures.

scholarly journals Case Report: ‘Z’ osteotomy - a novel technique of treatment in Blount’s disease

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 1250 ◽  
Author(s):  
Raju Karuppal ◽  
Rahul Mohan ◽  
Anwar Marthya ◽  
Gopakumar TS ◽  
Sandhya S
Keyword(s):  
Surgical Technique ◽  
Proximal Tibia ◽  
Blount’S Disease ◽  
Angular Correction ◽  
Poor Patient Compliance ◽  
Recovery Times ◽  
Prolonged Recovery ◽  
Surgical Treatments ◽  
New Surgical Technique

Blount’s disease is a progressive form of genu varum due to asymmetrical inhibition of the postero medial portion of the proximal tibial epiphysis. The surgical treatments involved in correction of Blount’s disease are often technically demanding, complicated procedures.  These procedures can lead to prolonged recovery times and poor patient compliance. In such a context we are suggesting “fibulectomy with Z osteotomy” of the proximal tibia, a relatively simple and highly effective technique. This technique is based on correcting the mechanical axis of the lower limb thereby restoring growth from the medial physis of proximal tibia. We have used a new surgical technique, which includes fibulectomy followed by a Z-shaped osteotomy. We have used this simple technique in a 5 year-old boy with unilateral Blount’s disease. The femoro-tibial angle was corrected from 18.2° of varus to 4.2° of valgus. The angular correction obtained after operation was 22°. There were no postoperative complications. This technique has the advantages of correcting both angular and rotational deformities simultaneously.  The purpose of this case study is to introduce a new surgical technique in the treatment of Blount’s disease.

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