scholarly journals Number of Board-Certified Cardiologists and Acute Myocardial Infarction-Related Mortality in Japan　― JROAD and JROAD-DPC Registry Analysis ―

2018 ◽  
Vol 82 (11) ◽  
pp. 2845-2851 ◽  
Author(s):  
Koshiro Kanaoka ◽  
Satoshi Okayama ◽  
Kihei Yoneyama ◽  
Michikazu Nakai ◽  
Kunihiro Nishimura ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Registry Analysis ◽  
Related Mortality

scholarly journals A Long-Forgotten Tale: The Management of Cardiogenic Shock in Acute Myocardial Infarction

2018 ◽  
Vol 4 (4) ◽  
pp. 170-177
Author(s):  
Adrian Corneliu Iancu ◽  
Mihaela Ioana Dregoesc ◽  
Aurelia Solomoneanu ◽  
Theodora Benedek
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiogenic Shock ◽  
Mechanical Support ◽  
St Segment Elevation ◽  
Medical Centers ◽  
Life Saving ◽  
St Segment ◽  
Elevation Acute Myocardial Infarction ◽  
Related Mortality

Abstract Patients with acute myocardial infarction (AMI) complicated with cardiogenic shock (CS) present one of the highest mortality rates recorded in critical care. Mortality rate in this setting is reported around 45-50% even in the most experienced and well-equipped medical centers. The continuous development of ST-segment elevation acute myocardial infarction (STEMI) networks has led not only to a dramatic decrease in STEMI-related mortality, but also to an increase in the frequency of severely complicated cases who survive to be transferred to tertiary centers for life-saving treatments. The reduced effectiveness of vasoactive drugs on a severely altered hemodynamic status led to the development of new devices dedicated to advanced cardiac support. What’s more, efforts are being made to reduce time from first medical contact to initiation of mechanical support in this particular clinical context. This review aims to summarize the most recent advances in mechanical support devices, in the setting of CS-complicated AMI. At the same time, the review presents several modern concepts in the organization of complex CS centers. These specialized hubs could improve survival in this critical condition.

scholarly journals Impact of a Preexisting STEMI Network in Improving STEMI Diagnostic and Treatment in the Community after the Introduction of a National Program of Interventional Treatment in Acute myocardial Infarction

2015 ◽  
Vol 1 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Marius Orzan ◽  
Theodora Benedek ◽  
Balázs Bajka ◽  
Kinga Pál ◽  
Nora Rat ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Interventional Treatment ◽  
Primary Pci ◽  
National Program ◽  
Treatment Rate ◽  
Invasive Treatment ◽  
European Guidelines ◽  
The Impact ◽  
Related Mortality

Abstract Introduction: According to European guidelines, ST elevation acute myocardial infarction should be treated by immediate reperfusion, if diagnosed within 12 hours from the onset of symptoms. We aimed to show the impact of a well-functioning pre-existing STEMI network in improving the results of a national program dedicated to the invasive treatment of AMI. Methods: We followed the comparison between primary PCI rates and STEMI-related mortality in two regions, after the introduction of a nationwide program for the interventional treatment of acute myocardial infarction: region A, where the territory has been appropriately prepared via previous organizational measures in the network, and region B, where the territory has not been previously prepared. Results: In 2011, one year after the initiation of the national program, a primary PCI rate of 12.1%, a thrombolysis rate of 10.1% and a no-reperfusion treatment rate of 77.8% have been found in these new centers for patients arriving <12 h from symptoms onset. This has been reflected in a mortality of 23.07% for “early presentations” in these new centers in 2011. In comparison, data from the territorial hospitals of the registry (only those without cathlab facilities, similar to the new centers) showed in 2011 a 73.85% primary PCI rate, 12.09% thrombolysis rate and a 14.07% conservative treatment rate, reflected in a mortality of 6.81% for “early presentations” in the registry centers. Conclusions: The national strategy for reduction of STEMI related mortality via implementation of primary PCI, started in 2010, had a significant impact especially in that region where the territory was previously prepared with appropriate organizational efforts, including educational and logistic measures.

Lipids, myocardial infarction and ischaemic stroke in patients with rheumatoid arthritis in the Apolipoprotein-related Mortality RISk (AMORIS) Study

2010 ◽  
Vol 69 (11) ◽  
pp. 1996-2001 ◽  
Author(s):  
A G Semb ◽  
T K Kvien ◽  
A H Aastveit ◽  
I Jungner ◽  
T R Pedersen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Regression Analysis ◽  
Ischaemic Stroke ◽  
Mortality Risk ◽  
Predictive Value ◽  
Cox Regression ◽  
Cox Regression Analysis ◽  
Related Mortality

ObjectivesTo examine the rates of acute myocardial infarction (AMI) and ischaemic stroke (IS) and to examine the predictive value of total cholesterol (TC) and triglycerides (TG) for AMI and IS in patients with rheumatoid arthritis (RA) and people without RA.MethodsIn the Apolipoprotein MOrtality RISk (AMORIS) Study 480 406 people (including 1779 with RA, of whom 214 had an AMI and 165 an IS) were followed for 11.8 (range 7–17) years. Cox regression analysis was used to calculate HR per SD increase in TC or TG with 95% CI. All values were adjusted for age, diabetes and hypertension.ResultsThe levels of TC and TG were significantly lower in patients with RA than in people without RA. Despite this, the rate of AMI and IS per 1000 years was at least 1.6 times higher in RA than non-RA. TC was nearly significantly predictive for AMI (HR/SD 1.13 (95% CI 0.99 to 1.29), p=0.07) and significantly predictive for future IS in RA (HR/SD 1.20 (95% CI 1.03 to 1.40), p=0.02). TG had no relationship to development of AMI (1.07, 0.94 to 1.21, p=0.29), but was weakly related to IS (1.13, 0.99 to 1.27, p=0.06). In contrast, both TC and TG were significant predictors of AMI and IS in people without RA.ConclusionsPatients with RA had 1.6 times higher rate of AMI and IS than people without RA. TC and TG were significant predictors of AMI and IS in people without RA, whereas the predictive value in RA was not consistent.

An electron microscopic study of the intra-myocardial lesions in cases of acute myocardial infarction

1978 ◽  
Vol 36 (2) ◽  
pp. 484-485
Author(s):  
Masahiro Ono ◽  
Kaoru Aihara ◽  
Gompachi Yajima
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Vessels ◽  
Vascular Wall ◽  
Vascular Changes ◽  
Electron Microscopic ◽  
Main Trunk ◽  
Mechanical Destruction ◽  
Transmission Electron ◽  
Myocardial Lesions

The pathogenesis of the arteriosclerosis in the acute myocardial infarction is the matter of the extensive survey with the transmission electron microscopy in experimental and clinical materials. In the previous communication,the authors have clarified that the two types of the coronary vascular changes could exist. The first category is the case in which we had failed to observe no occlusive changes of the coronary vessels which eventually form the myocardial infarction. The next category is the case in which occlusive -thrombotic changes are observed in which the myocardial infarction will be taken placed as the final event. The authors incline to designate the former category as the non-occlusive-non thrombotic lesions. The most important findings in both cases are the “mechanical destruction of the vascular wall and imbibition of the serous component” which are most frequently observed at the proximal portion of the coronary main trunk.

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