scholarly journals Pharmacological properties of paliperidone ER (INVEGA®) and results of its clinical studies

2011 ◽  
Vol 137 (6) ◽  
pp. 245-254 ◽  
Author(s):  
Kenji Nagino ◽  
Tadaishi Koh ◽  
Yasushi Harada
Author(s):  
Hamed Fathi ◽  
Fatemeh Faraji ◽  
Niusha Esmaealzadeh ◽  
Shahram Eslami ◽  
Mohammad Bagher Mohammadi Laeeni

Introduction: Zingiber officinale Rose (ginger) has been used for many purposes in traditional medicine since 2500 years ago. This study intends to introduce the ginger plant, some of their applications in the field of human health in traditional and modern medicine, and their conformity with Islamic and Quranic findings. Material and Methods: Administrative and therapeutic information of ginger plant has been searched in related and valid books, scientific databases including Web of Science, PubMed, SID, Google Scholar, and Scopus. Ginger keyword has been searched in the Quran and hadiths and its medicinal and pharmacological properties; also in traditional Persian medicine and laboratory studies, the day, was collected from published articles. In order to confirm the obtained information, it was matched with Quranic and narration versions, and the obtained information was analyzed, compiled, and presented. Results: Avicenna has mentioned the positive effects of ginger in his Canon of Medicine. The Food and Drug Administration of the Ministry of Health in Iran has also introduced ginger as a dietary supplement. Ginger is one of those plants which name is mentioned in the Quran, in verse 17 of Surah Al-Insan. In narrations and quoting scientists as well as in modern medicine and articles, the effects and application of this plant in the field of medicine and nutrition have been mentioned. Conclusion: The results have shown that the use of ginger in nutrition as a spice or supplement and in Persian medicine as a medicament has a scientific and practical basis, and studies on this issue are confirmed both in science and Islam. Findings obtained from laboratory and clinical studies can also be effective in the proper use and preparation of appropriate medicinal forms of this plant.


2015 ◽  
Vol 145 (2) ◽  
pp. 92-99
Author(s):  
Kenji Nagino ◽  
Kenichiro Tsutsumi ◽  
Miwako Ishido ◽  
Yasushi Harada

2013 ◽  
Vol 141 (4) ◽  
pp. 205-211
Author(s):  
Michiko Iwata ◽  
Koji Shikinami ◽  
Kenji Nagino ◽  
Yasushi Harada

2012 ◽  
Vol 10 (3) ◽  
pp. 40-49 ◽  
Author(s):  
Oleg Dmitriyevich Barnaulov ◽  
Tatyana Vladimirovna Osipova

A brief review of the N. V. Lazarev school study of the pharmacological properties of the classical phytoadaptogens. As the result of this research was creation a theory of state nonspecific body increased resistance induced by phytoadaptogens, and the discovery of their stress-limiting properties. Presented own data of first time comparative evaluation of anti-stress action of phytoadaptogens in the model of immobilization stress. Revealed in own clinical studies a high efficiency of polycomponent phytotherapy, including a large number of phytoadaptogens in the treatment of patients with multiple sclerosis.


2021 ◽  
Vol 12 (3) ◽  
pp. 588-592
Author(s):  
Choudhari D D ◽  
Kulkarni Y R ◽  
Visave P B

Abhava pratinidhi dravya excites the scientific curiosity concerning the Ayurvedic principles behind selection of the substitute drug. Present study had reported a comparative phytochemical study of one such Ayurvedic substitution pair: Solanum surattense Burm.f., a substitute for Clerodendrum serratum L. The study was conducted to understand the logic behind the Abhava pratinidhi dravya (Drug substitution). The strategy was to scrutinize and compare their Ayurvedic properties by literary studies and test the phytochemical profile of these two herbs for biochemical similiarties and differences. On analyzing their Ayurvedic pharmacology (Dravyaguna properties), findings show that both the drugs possess katu and tikta rasa, but Bharangi is katu rasa dominant and Kantakari is tikta rasa dominant drug. Along with this, both drug possess laghu, ruksha and ushna guna in common. Kantakari which contain different properties i.e. sara and tikshna guna. Both drug possess katu vipaka and ushna veerya. Both drugs had been stated to treat majority of respiratory ailments. Phytochemical observations suggest that in Bharangi root extract alkaloids and tannins was present whereas Kantakari root extract was rich in flavonoids content. Saponins was present in maximum amount in both the plant extracts. Despite taxonomically unrelated and morphologically dissimiliar, Bharangi has been substituted by Kantakari drug. In Ayurveda, more importance was given to pharmacological properties of raw drug rather than its botanical classification. Further comparative pre-clinical studies and bio-equivalence clinical studies has been needed to explore the different pharmacological properties.


1950 ◽  
Vol 16 (4) ◽  
pp. 743-756 ◽  
Author(s):  
Charles A. Jones
Keyword(s):  

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