scholarly journals Monitoring of the application of laminating adhesives to polyurethane foam by near infrared chemical imaging

Author(s):  
G. Mirschel ◽  
O. Daikos ◽  
C. Steckert ◽  
T. Scherzer
2007 ◽  
Vol 15 (3) ◽  
pp. 137-151 ◽  
Author(s):  
Hua Ma ◽  
Carl A. Anderson

A critical parameter in the evaluation of pharmaceutical dosage forms by hyperspectral imaging is the level of magnification. If the magnification (as set by the optical objective) is inadequate to resolve the relevant features, then the value of the imaging is diminished; if the magnification level is greater than is required, then the field of view is unnecessarily reduced. The purpose of this study was to determine an optimum magnification level for the study of powder mixing. Relevant features in this system include distribution of individual components within samples and the overall content of a given sample. In the present study, three magnification levels of near infrared (NIR) chemical imaging objectives were evaluated for their effects on imaging a blend of pharmaceutical materials (powders). High, medium and low objective magnification levels were investigated by comparing the resulting blend surface images of a two-component (salicylic acid and lactose) pharmaceutical powder mixture. Multiple images from high and medium magnification were concatenated so that an equivalent field of view was obtained for all magnification levels. Univariate images, principal component analysis score images, partial least squares predicted images and spectra extracted from different intensity regions in the area images were analysed qualitatively and quantitatively for comparison. A series of images spanning a strip across the centre of the circular field were collected at each magnification level and compared with respect to surface features elucidated and area of blend surface imaged. Analyses of images indicate that the three magnification levels delineate the component distribution for this particular powder system similarly. Images obtained at the low magnification level demonstrated adequate resolution and provided the broadest view of the blend surface. It is concluded that the low optical magnification level was adequate for the system being studied and is the preferred mode for pharmaceutical powder blend image data collection for this system.


NIR news ◽  
2011 ◽  
Vol 22 (3) ◽  
pp. 10-18 ◽  
Author(s):  
Marta B. Lopes ◽  
Jean-Claude Wolff ◽  
José M. Bioucas-Dias ◽  
Mário A.T. Figueiredo

2012 ◽  
Vol 482-484 ◽  
pp. 1515-1519
Author(s):  
Zhi Guo Zhang ◽  
Hong Zhang Chen

Recently, some solid state fermentation (SSF) processes of xanthan production were studied. However, quantitative analysis of the concentration of xanthan and biomass is more complicated than that of submerged fermentation. To facilitate the analysis of these components, near–infrared spectroscopy (NIRS) was used. A NIRS calibration models for rapidly estimating xanthan and biomass concentration in xanthan fermentation on inert support of polyurethane foam was established. The wavenumber and spectral pretreatment method were optimized. The data of cross validation and external validation shows that NIRS was suitable for rapid and accurate quantification of the concentration of xanthan and biomass in solid state fermentation on inert support. This method will provide much convenience for the research of solid state fermentation on inert support.


2018 ◽  
Vol 90 (7) ◽  
pp. 4354-4362 ◽  
Author(s):  
Davinia Brouckaert ◽  
Laurens De Meyer ◽  
Brecht Vanbillemont ◽  
Pieter-Jan Van Bockstal ◽  
Joris Lammens ◽  
...  

2001 ◽  
Vol 7 (S2) ◽  
pp. 162-163
Author(s):  
EN Lewis ◽  
LH Kidder ◽  
KS Haber

Single point near-infrared (NIR) spectroscopy is used extensively for characterizing raw materials and finished products in a wide variety of industries: polymers, paper, film, pharmaceuticals, paintings and coatings, food and beverages, agricultural products. As advanced industrial materials become more complex, their functionality is often determined by the spatial distribution of their discrete sample constituents. However, conventional single point NIR spectroscopy cannot adequately probe the interrelationship between the spatial distribution of sample components with the physical properties of the sample. to fully characterize these samples, it is necessary to probe simultaneously spatial and chemical heterogeneity and correlate these properties with sample characteristics.Recently, we have developed a novel NIR imaging spectrometer that can deliver spatially resolved chemical information very rapidly. in contrast to conventional, single point NIR spectrometers, the imaging system uses an infrared focal-plane array (FPA) to collect up to 76,800 complete spectra, one for each pixel on the array, in approximately one minute.


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