Mucocutaneous leishmaniasis in a patient with the human immunodeficiency virus

2001 ◽  
Vol 12 (10) ◽  
pp. 687-689 ◽  
Author(s):  
P Sánchez ◽  
R J Bosch ◽  
M V de Gálvez ◽  
A B Rodrigo ◽  
E Herrera
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Disease Control ◽  
Previous History ◽  
Mediterranean Coast ◽  
Southern Spain ◽  
Mucocutaneous Leishmaniasis ◽  
Immunodeficiency Virus ◽  
History Of ◽  
The Mediterranean

We report a case of mucocutaneous leishmaniasis (MCL) in a patient with the human immunodeficiency virus (HIV), Centers for Disease Control (CDC) Stage A2, with no previous history of cutaneous or systemic leishmaniasis. The patient had not travelled outside the province of Málaga, on the Mediterranean coast of southern Spain, so that it concerns an indigenous case, extremely unusual in this area. The HIV infection may well have influenced the defence against leishmania, but the exact mechanism by which this occurred is unknown.

Decreased Thymus Size on Chest Radiography: A Sign of Pediatric Human Immunodeficiency Virus Infection?

PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 99-102
Author(s):  
ALAN MEYERS ◽  
NICHOLAS PEPE ◽  
WILLIAM CRANLEY ◽  
KATHLEEN MCCARTEN
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Chest Radiography ◽  
Pediatric Hiv ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Generalized Lymphadenopathy ◽  
Immunodeficiency Syndrome ◽  
Thymus Size

The early diagnosis of infection with the human immunodeficiency virus (HIV) in infancy is clinically important but remains problematic in the asymptomatic child born to an HIV-infected mother. In addition, many such women are unaware of their HIV infection until their child manifests symptomatic HIV disease. Nonspecific signs of pediatric HIV infection, such as generalized lymphadenopathy, hepatosplenomegaly, or persistent thrush, may be important in alerting the clinician to consider the possibility of HIV infection in the child whose history of HIV risk is unknown. We report one such sign which may be evident on plain chest radiography. The pathology of the thymus gland in pediatric acquired immunodeficiency syndrome has been described by Joshi and colleagues,1-3 who have reported precocious involution with marked reduction in thymus size and weight.

History of Human Immunodeficiency Virus Infection and the Nervous System

2017 ◽  
Author(s):  
Avindra Nath
Keyword(s):  
Human Immunodeficiency Virus ◽  
Nervous System ◽  
Hiv Infection ◽  
System P ◽  
Clinical Syndromes ◽  
Tremendous Progress ◽  
Immunodeficiency Virus ◽  
History Of ◽  
The Brain ◽  
First Descriptions

It has been nearly three decades since the first descriptions of the neurological comploications of HIV infection. During this period of time there has been tremendous progress in defining the clinical syndromes, modes of diagnosis, detailed pathophysiology and modes of treatment. Many of the dreaded complications are now manageable particularly if diagnosed early. However, neurocognitive impairment associated with HIV infection still remains a significant cause of morbidity and much is needed to control; the effects of the virus on the brain and for the eventual eradication of the virus from the brain reservoir.

Cutaneous manifestations of HIV-1 infection

1995 ◽  
Vol 85 (7) ◽  
pp. 362-374 ◽  
Author(s):  
O Memar ◽  
R Cirelli ◽  
P Lee ◽  
SK Tyring
Keyword(s):  
Human Immunodeficiency Virus ◽  
Immune System ◽  
Virus Infection ◽  
Hiv Infection ◽  
Cutaneous Manifestations ◽  
Immunodeficiency Virus ◽  
The Status ◽  
History Of ◽  
Hiv 1

Infection with the human immunodeficiency virus (HIV) leads to a chronic disarmament of the immune system. The process is progressive, having different manifestations as the status of the immune system slowly deteriorates. Some of the most common manifestations of HIV infection are cutaneous in origin, and they can have infectious, neoplastic, or noninfectious or non-neoplastic etiologies. A brief history of HIV is given, and the most common cutaneous presentations of the virus infection of interest to podiatrists are outlined.

scholarly journals Blindness in a Woman With Human Immunodeficiency Virus Infection and Syphilis

1995 ◽  
Vol 3 (5) ◽  
pp. 198-201
Author(s):  
Michael Luchi ◽  
Curtis Beauregard ◽  
Kevin Ault ◽  
Daniel Hinthorn
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cerebrospinal Fluid ◽  
Virus Infection ◽  
Hiv Infection ◽  
Skin Lesions ◽  
High Dose ◽  
Progressive Loss ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Hands And Feet

Background: A concomitant infection with human immunodeficiency virus (HIV) may alter the natural history of other infections. Several reports indicate that syphilis may behave more aggressively when HIV infection is present.Case: A woman presented with a rash involving her hands and feet and progressive loss of the vision in her right eye. Her serologic tests for syphilis and HIV infection were positive. A diagnosis of neurosyphilis was confirmed by an analysis of cerebrospinal fluid (CSF). She was treated with high-dose intravenous (IV) penicillin. Her skin lesions resolved, but her vision did not improve.Conclusion: The incidence of HIV infection among women is rising. A patient with HIV and syphilis may develop neurosyphilis in a much shorter time than a patient without HIV infection.

Human Immunodeficiency Virus Hematology

Hematology ◽  
2003 ◽  
Vol 2003 (1) ◽  
pp. 294-313 ◽  
Author(s):  
Paul A. Volberding ◽  
Kelty R. Baker ◽  
Alexandra M. Levine
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Hiv Care ◽  
Hiv Disease ◽  
Secondary Infections ◽  
Antiretroviral Drug ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Relationship Of

Abstract The advent of potent antiretroviral therapy has altered the expected natural history of human immunodeficiency virus (HIV) infection and of many previously associated opportunistic complications, including malignancies. At the same time, HIV suppression hasn’t affected all of these complications equally and the longer expected survival of infected patients may allow the development of newer complications. Additionally, the use of potent antiretroviral combination therapy may itself lead to hematological toxicities. Together these changes affect the consultation role of the hematology-oncology specialist in comprehensive HIV care and demand ongoing education. In Section I, Dr. Paul Volberding reviews the biology of antiretroviral drug development and the progression in discovering new agents as the viral life cycle is further elucidated. He briefly summarizes the process of combining agents to achieve the degree of viral suppression required for long-term clinical benefit. In Section II, Dr. Kelty Baker reviews the effects of HIV and its therapy on hematologic dyscrasia and clotting disorders. She summarizes how therapy may decrease certain previously common manifestations of HIV disease while adding new problems likely to result in referral to the hematologist. In addition, she addresses the role of secondary infections, such as parvovirus, in this spectrum of disorders. In Section III, Dr. Alexandra Levine discusses the still challenging aspects of HIV associated non-Hodgkin’s lymphoma and the association between HIV infection and Hodgkin’s disease. She addresses current controversies in the pathogenesis of HIV related lymphomas and summarizes a number of recent trials of combination chemotherapy, with or without monoclonal antibodies, in their management. Additionally, she reviews the complex relationship of HIV disease with multicentric Castleman’s disease and recent attempts to manage this disorder.

Natural History of Vertically Acquired Human Immunodeficiency Virus-1 Infection

PEDIATRICS ◽  
1994 ◽  
Vol 94 (6) ◽  
pp. 815-819 ◽  
Author(s):  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Natural History ◽  
Hiv Infection ◽  
Health Planning ◽  
Collaborative Study ◽  
Steady Increase ◽  
Immunodeficiency Virus ◽  
Progression Of Disease ◽  
History Of ◽  
Immunodeficiency Syndrome

Objective. To describe the natural history of vertically acquired human immunodeficiency virus (HIV) infection. Design. This was a prospective follow-up study. Setting. Ten centers of the European Collaborative Study participated. Subjects. One hundred twenty-four HIV-infected children were born to women known to be infected at or before the time of delivery since 1986. Main outcome measures. Deaths, acquired immunodeficiency syndrome (AIDS), and HIV-related symptoms and signs were assessed. Results. In this cohort, treatment before the onset of AIDS was not universal. Less than 10% of children were treated with Zidovudine or intravenous gamma globulin before 6 months of age, with a steady increase to about 40% after 3 years of life. An estimated 23% (95% confidence interval: 15% to 31%) of infected children develop AIDS before the age of 1 year, and nearly 40% (27% to 50%) by 4 years. Ten percent (5% to 16%) die before age 1 year and 28% (16% to 41%) before age 5 years. Twenty-four months after the AIDS diagnosis, an estimated 48% (36% to 70%) of the children are still alive. Although after the age of 1 year immunologic abnormalities became increasingly common, the proportion of infected children with significant HIV-related symptoms or signs declined. Conclusion. The progression of disease in this cohort of vertically infected children was not as fast as previously suggested, even though treatment was not widespread. Although infected children have a high risk of developing some manifestation of HIV infection early in life, serious HIV-related symptoms became less frequent with increasing age. This has important implications for health planning and care provision.

Leukocytoclastic vasculitis associated with nontyphoidal Salmonella in a patient infected with human immunodeficiency virus

2020 ◽  
Vol 31 (4) ◽  
pp. 383-386
Author(s):  
Gonzalo Cornejo-Venegas ◽  
Juan José Montenegro-Idrogo ◽  
Cristhian Resurrección-Delgado ◽  
Carolina Mendez-Guerra ◽  
Andres Quevedo-Ramirez ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Hiv Infection ◽  
Leukocytoclastic Vasculitis ◽  
Clinical Stage ◽  
Corticosteroid Treatment ◽  
Skin Lesions ◽  
Meningococcal Infection ◽  
Immunodeficiency Virus ◽  
History Of

A 27-year-old Peruvian woman living with human immunodeficiency virus (HIV) in clinical stage B3 and not on antiretroviral therapy presented with a ten-day history of fever, chills, night sweats and a two-day history of skin lesions. On physical examination, several erythematous-purplish lesions were found on the face and legs. Meningococcal infection was suspected and ceftriaxone was started. Blood culture grew nontyphoidal Salmonella enterica. A biopsy of the skin lesions showed leukocytoclastic vasculitis (LCV); therefore, corticosteroids were added. After two weeks of antibiotic and corticosteroid treatment, the lesions had resolved, but they recurred two days after treatment with prednisone was stopped. Corticosteroids and combination antiretroviral therapy were started simultaneously and the lesions resolved without recurrence. HIV infection has been associated with higher rates of skin lesions in salmonellosis. LCV has been described both in the setting of HIV infection and salmonellosis. However, our review of the literature found no previous cases of LCV in concurrent HIV and salmonellosis.

scholarly journals Synchronous and metachronous malignant melanomas arising in a human immunodeficiency virus-positive patient after the commencement of highly active antiretroviral therapy treatment: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Sharad P. Paul ◽  
Simon Briggs ◽  
Michael Hitchcock
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Previous History ◽  
Case Presentation ◽  
Highly Active ◽  
Immunodeficiency Virus ◽  
History Of

Abstract Background We present an unusual case of a patient who developed four melanomas within a few months of diagnosis with human immunodeficiency virus and commencement of highly active antiretroviral therapy therapy. The patient had no previous history of melanoma, and previous skin checks were normal. Case presentation A 50-year-old Caucasian male drainlayer with Fitzpatrick type 2 skin presented for a routine skin examination. He had been diagnosed with human immunodeficiency virus 4 months earlier and commenced on highly active antiretroviral therapy therapy. He was found to have three melanomas (melanoma in situ stage) on excision biopsies, and when he presented for wider excisions of these sites a few weeks later, another new melanoma in situ was found. He had no other medical history of note, and no symptoms to report. He is being followed up 3-monthly. Conclusions This case of a human immunodeficiency virus-positive person presenting with four cutaneous melanomas—occurring in both synchronous and metachronous fashion within a 4-month period—is being presented both for its uniqueness and also to highlight the increased need for close skin surveillance in human immunodeficiency virus-positive patients.

Sign in / Sign up

Export Citation Format

Share Document