scholarly journals Contrast-enhanced mammography: what the radiologist needs to know

BJR|Open ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 20210034
Author(s):  
Lidewij M.F.H. Neeter ◽  
H.P.J. (Frank) Raat ◽  
Rodrigo Alcantara ◽  
Quirien Robbe ◽  
Marjolein L. Smidt ◽  
...  
Keyword(s):  
Breast Imaging ◽  
Contrast Material ◽  
High Energy ◽  
Dual Energy ◽  
Everyday Clinical Practice ◽  
Future Developments ◽  
Imaging Protocols ◽  
Iodinated Contrast ◽  
Contrast Enhanced ◽  
The Subject

Contrast-enhanced mammography (CEM) is a combination of standard mammography and iodinated contrast material administration. During the last decade, CEM has found its place in breast imaging protocols: after i.v. administration of iodinated contrast material, low-energy and high-energy images are retrieved in one acquisition using a dual-energy technique, and a recombined image is constructed enabling visualisation of areas of contrast uptake. The increased incorporation of CEM into everyday clinical practice is reflected in the installation of dedicated equipment worldwide, the (commercial) availability of systems from different vendors, the number of CEM examinations performed, and the number of scientific articles published on the subject. It follows that ever more radiologists will be confronted with this technique, and thus be required to keep up to date with the latest developments in the field. Most importantly, radiologists must have sufficient knowledge on how to interpret CEM images and be acquainted with common artefacts and pitfalls. This comprehensive review provides a practical overview of CEM technique, including CEM-guided biopsy; reading, interpretation and structured reporting of CEM images, including the accompanying learning curve, CEM artefacts and interpretation pitfalls; indications for CEM; disadvantages of CEM; and future developments.

scholarly journals Contrast-Induced Acute Kidney Injury: Definition, Epidemiology, and Outcome

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Felix G. Meinel ◽  
Carlo N. De Cecco ◽  
U. Joseph Schoepf ◽  
Richard Katzberg
Keyword(s):  
Acute Kidney Injury ◽  
Renal Function ◽  
Renal Insufficiency ◽  
Time Window ◽  
Contrast Material ◽  
Kidney Injury ◽  
Preventive Strategy ◽  
Iodinated Contrast ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced

Contrast-induced acute kidney injury (CI-AKI) is commonly defined as a decline in kidney function occurring in a narrow time window after administration of iodinated contrast material. The incidence of AKI after contrast material administration greatly depends on the specific definition and cutoff values used. Although self-limiting in most cases, postcontrast AKI carries a risk of more permanent renal insufficiency, dialysis, and death. The risk of AKI from contrast material, in particular when administered intravenously for contrast-enhanced CT, has been exaggerated by older, noncontrolled studies due to background fluctuations in renal function. More recent evidence from controlled studies suggests that the risk is likely nonexistent in patients with normal renal function, but there may be a risk in patients with renal insufficiency. However, even in this patient population, the risk of CI-AKI is probably much smaller than traditionally assumed. Since volume expansion is the only preventive strategy with a convincing evidence base, liberal hydration should be encouraged to further minimize the risk. The benefits of the diagnostic information gained from contrast-enhanced examinations will still need to be balanced with the potential risk of CI-AKI for the individual patient and clinical scenario.

scholarly journals Exploring silver as a contrast agent for contrast-enhanced dual-energy X-ray breast imaging

2014 ◽  
Vol 87 (1041) ◽  
pp. 20140081 ◽  
Author(s):  
R Karunamuni ◽  
A Tsourkas ◽  
A D A Maidment
Keyword(s):  
Contrast Agent ◽  
Breast Imaging ◽  
Dual Energy ◽  
X Ray ◽  
Contrast Enhanced

scholarly journals Contrast enhanced dual energy spectral mammogram, an emerging addendum in breast imaging

2016 ◽  
Vol 89 (1067) ◽  
pp. 20150609 ◽  
Author(s):  
Kalpana D Kariyappa ◽  
Francis Gnanaprakasam ◽  
Subhapradha Anand ◽  
Murali Krishnaswami ◽  
Madan Ramachandran
Keyword(s):  
Breast Imaging ◽  
Dual Energy ◽  
Contrast Enhanced

Value of multidetector computed tomography in assessing blunt multitrauma patients

2005 ◽  
Vol 46 (2) ◽  
pp. 177-183 ◽  
Author(s):  
L. Ahvenjärvi ◽  
L. Mattila ◽  
R. Ojala ◽  
O. Tervonen
Keyword(s):  
Computed Tomography ◽  
Cervical Spine ◽  
Multidetector Computed Tomography ◽  
False Negative ◽  
Contrast Material ◽  
High Energy ◽  
Facial Bones ◽  
Imaging Protocol ◽  
Iodinated Contrast ◽  
Negative Findings

Purpose: To find out if multidetector computed tomography (MDCT), using a dedicated trauma protocol, provides sufficient diagnostic information of the injuries of blunt multitrauma patients to enable the planning of treatment for all body compartments. Material and Methods: One‐hundred‐and‐thirty‐three patients exposed to high‐energy trauma were referred and scanned with the standardized MDCT multitrauma protocol. The imaging protocol consisted of axial scanning of the head and helical scanning of the facial bones, cervical spine, thorax, abdomen, and pelvis. The scanning times were 12 s for the head, 19–21 s for the facial bones and cervical spine (1 mm collimation), and 32–50 s for the thorax, abdomen, and pelvis (2 mm collimation). One‐hundred‐and‐forty milliliters of non‐iodinated contrast material (300 mg I/ml) was administered intravenously at 3 ml/s. Results: Ninety‐nine of the patients (74%) had at least one finding consistent with trauma. The most frequent findings were in the thorax in 58 patients (44%). Nineteen false‐negative findings and two false‐positive findings were made. The overall sensitivity of MDCT was 94%, specificity 100%, and accuracy 97%. Conclusion: MDCT is accurate in the assessment of blunt multitrauma patients. The decision to treat the patient can be made on the basis of MDCT with a reasonable level of certainty.

scholarly journals Current Status of Contrast Enhanced Mammography: A Comprehensive Review

2021 ◽  
pp. 084653712110290
Author(s):  
Anat Kornecki
Keyword(s):  
Breast Imaging ◽  
Dual Energy ◽  
Current Status ◽  
Resonance Imaging ◽  
Comprehensive Review ◽  
Full Field ◽  
Dce Mri ◽  
Full Field Digital Mammography ◽  
Contrast Enhanced ◽  
Diagnostic Setting

Objectives: The purpose of this article is to provide a detailed and updated review of the physics, techniques, indications, limitations, reporting, implementation and management of contrast enhanced mammography. Background: Contrast enhanced mammography (CEM), is an emerging iodine-based modified dual energy mammography technique. In addition to having the same advantages as standard full-field digital mammography (FFDM), CEM provides information regarding tumor enhancement, relying on tumor angiogenesis, similar to dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). This article reviews current literature on CEM and highlights considerations that are critical to the successful use of this modality. Conclusion: Multiple studies point to the advantage of using CEM in the diagnostic setting of breast imaging, which approaches that of DCE-MRI.

TU-D-L100J-07: The Use of CT Dual-Energy Subtraction Imaging to Detect Kidney Stones Amid Iodinated Contrast Material

2007 ◽  
Vol 34 (6Part18) ◽  
pp. 2555-2555
Author(s):  
OP Dzyubak ◽  
AN Primak ◽  
N Takahashi ◽  
TJ Vrtiska ◽  
RP Hartman ◽  
...  
Keyword(s):  
Kidney Stones ◽  
Contrast Material ◽  
Dual Energy ◽  
Iodinated Contrast ◽  
Energy Subtraction ◽  
Subtraction Imaging

scholarly journals Quantitative breast density in Contrast-Enhanced Mammography

2021 ◽  
Author(s):  
Gisella Gennaro ◽  
Melissa L. Hill ◽  
Elisabetta Bezzon ◽  
Francesca Caumo
Keyword(s):  
Breast Cancer ◽  
Breast Density ◽  
Breast Imaging ◽  
High Energy ◽  
Multiple Correlation Coefficient ◽  
Low Energy ◽  
Wilcoxon Test ◽  
Coefficient Of Determination ◽  
Contrast Enhanced ◽  
Significant Difference

Abstract Background: Breast density is an independent risk factor for breast cancer, and cancer detection in mammography is reduced in dense breasts. Quantitative tools are available to measure breast density from digital mammography (DM) or tomosynthesis (DBT). Contrast-enhanced mammography (CEM) is an emerging breast imaging technique, consisting of the acquisition of an image pair (low-energy, LE, and high-energy, HE) for each mammography view. LE-CEM images have been demonstrated to be visually equivalent to a standard mammogram, thereby, CEM examinations do not require additional mammography to complete the clinical information. In this study, volumetric breast density (VBD) measured in LE-CEM was compared with VBD obtained from DM/DBT images.Methods: Between Mar 2019 and Dec 2020 222 women were enrolled in a prospective clinical trial aiming to compare clinical performance of CEM with breast MRI in a population of women at intermediate and high risk for breast cancer. In this observational cohort study, 150 women enrolled in this trial having at least a DM/DBT study performed before/after CEM were selected. CEM and previous/subsequent DM/DBT images were processed by an automatic algorithm to calculate VBD for each view. VBD from LE-CEM and DM/DBT views were compared using a paired Wilcoxon test. P < 0.05 was considered indicative of a statistically significant difference. A multivariate regression model was applied to analyze the relationship between paired VBD differences and multiple independent variables certainly or potentially affecting VBD.Results: Mean age of women included in this study was 51.0±8.4 years. Median VBD was comparable for LE-CEM and previous/subsequent DM/DBT (12.73% vs. 12.39%), not evidencing any statistically significant difference (P = 0.5855). VBD differences between LE-CEM and DM were associated to significant differences of glandular volume, breast thickness, compression force and pressure, contact area, and nipple-to-posterior-edge distance i.e. variables reflecting differences in breast positioning (coefficient of determination 0.6023; multiple correlation coefficient 0.7761).Conclusions: Volumetric breast density can be obtained from low-energy contrast-enhanced spectral mammography and is not significantly different from volumetric breast density measured from standard mammograms.

scholarly journals CESM – Contrast Enhanced Spectral Mammography un nuovo paradigma per la diagnostica senologica

2020 ◽  
pp. 93-95 ◽  
Author(s):  
Stile Stefania ◽  
Scarfato Emma ◽  
Maiello Vincenzo ◽  
Aversano Valentina ◽  
Colombo Giovanni
Keyword(s):  
Magnetic Resonance Imaging ◽  
Digital Mammography ◽  
Dual Energy ◽  
High Contrast ◽  
Resonance Imaging ◽  
High Quality ◽  
Contrast Resolution ◽  
Iodinated Contrast ◽  
Contrast Enhanced ◽  
Magnetic Resonance Imaging Mri

Newly, analogic mammography has been completely replaced by digital mammography, which has allowed, with its high quality images and high contrast resolution, to improve diagnostic accuracy in screening populations and to develop applications such as CESM (Contrast Enhanced Spectral Mammography). The topic in this paper concerns the dual energy subtractive digital mammography, with iodinated contrast in a digital mammographic setting, which allows, as in magnetic resonance imaging (MRI), a contrast evaluation of the breast, highlighting the areas that capture the radiological contrast, typical expression of neoplastic neoangiogenesis.

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