Dietary Calcium Intake and HPV Infection Status Among American Women: A Secondary Analysis from National Health and Nutrition Examination Survey (NHANES) Data Set of 2003 – 2016

Abstract Background Human papillomavirus (HPV) infection is a major cause of cervical cancer. Studies showed the onset of HPV carcinogenesis may be induced by oxidative stress affecting the host immune system. The association between antioxidants and oncogenic HPV remains unclear. In this study, we aim to identify antioxidants associated with vaginal HPV infection in women. Methods The associations between the 15 antioxidants and vaginal HPV infection status (no, low-risk, and high-risk HPV [LR- and HR-HPV]) were evaluated using 11,070 women who participated in the 2003-2016 National Health and Nutrition Examination Survey (NHANES). Results We identified serum albumin and four dietary antioxidants (vitamin-A, -B2, -E, and folate) inversely associated with HR-HPV infection. Women with a low level of albumin (≤39 g/L) have a significantly higher risk of HR-HPV (OR=1.4, p=0.009 vs. >44 g/L). A nutritional antioxidant score (NAS) was developed based on these four dietary antioxidants. The women with the lowest quartile NAS had a higher chance of HR-HPV (OR=1.3, p=0.030) and LR-HPV (OR=1.4, p=0.002) compared with the women with the highest quartile NAS. Conclusions We identified five antioxidants negatively associated with vaginal HR-HPV infection in women. Our findings provide valuable insights into understanding antioxidants’ impact on HPV carcinogenesis.

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Dietary Calcium and Vitamin D Intakes in the United States: Data from the National Health and Nutrition Examination Survey (NHANES) 2003-2006

Journal of the American Dietetic Association ◽

10.1016/j.jada.2009.06.385 ◽

2009 ◽

Vol 109 (9) ◽

pp. A15

Author(s):

R.L. Bailey ◽

K. Dodd ◽

J. Gahche ◽

J. Dwyer ◽

M. McDowell ◽

...

Keyword(s):

United States ◽

Vitamin D ◽

National Health ◽

The United States ◽

Dietary Calcium ◽

Nutrition Examination Survey ◽

Health And Nutrition ◽

States Data

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Effects of calcium intake, milk and dairy product intake, and blood vitamin D level on osteoporosis risk in Korean adults: analysis of the 2008 and 2009 Korea National Health and Nutrition Examination Survey

Nutrition Research and Practice ◽

10.4162/nrp.2013.7.5.409 ◽

2013 ◽

Vol 7 (5) ◽

pp. 409 ◽

Cited By ~ 27

Author(s):

Heeok Hong ◽

Eun-Kyung Kim ◽

Jung-Sug Lee

Keyword(s):

Vitamin D ◽

National Health ◽

Calcium Intake ◽

Dairy Product ◽

Nutrition Examination Survey ◽

Korean Adults ◽

Health And Nutrition ◽

Osteoporosis Risk

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Association of Systemic Inflammation and Fatigue in Osteoarthritis: 2007−2010 National Health and Nutrition Examination Survey

Biological Research For Nursing ◽

10.1177/1099800419859091 ◽

2019 ◽

Vol 21 (5) ◽

pp. 532-543 ◽

Cited By ~ 1

Author(s):

Alisha J. Hackney ◽

N. Jennifer Klinedinst ◽

Barbara Resnick ◽

Meg Johantgen

Keyword(s):

Logistic Regression ◽

Systemic Inflammation ◽

National Health ◽

Regression Models ◽

Secondary Analysis ◽

Nutrition Examination Survey ◽

Cross Sectional ◽

Logistic Regression Models ◽

Health And Nutrition ◽

Wbc Count

Background/Purpose:Mechanistic insight into osteoarthritis fatigue is needed as clinical management of this condition is nonspecific. Systemic inflammation is associated with fatigue in other chronic diseases. The purpose of this study was to explore the relationship between systemic inflammation and fatigue in osteoarthritis, while controlling for covariates.Method:This secondary analysis with a cross-sectional, multiyear retrospective design used data from the 2007−2010 National Health and Nutrition Examination Survey. Adults with self-reported osteoarthritis who participated in an examination at a mobile center and had no comorbidities associated with fatigue or systemic inflammation were included ( n = 296). Complex sample analysis, independent samples t tests, and χ2tests of independence were used to explore differences between nonfatigued and fatigued adults with osteoarthritis. Adjusted hierarchical logistic regression models were used to calculate odds of fatigue as a function of two systemic inflammatory markers, C-reactive protein (CRP), and white blood cell (WBC) count.Results:Fatigued adults with osteoarthritis had significantly higher CRP levels and WBC counts compared to nonfatigued adults with osteoarthritis. In adjusted logistic regression models, increased CRP was associated with higher odds of fatigue when controlling for age, days affected by pain, depressive symptoms, sleep quantity, and body mass index (Odds ratio [ OR] = 3.38, 95% CI [1.18, 9.69]). WBC count was not associated with higher odds of fatigue when controlling for these variables ( OR = 1.10, 95% CI [0.92, 1.32]).Conclusion:Systemic inflammation may have a relationship with fatigue in osteoarthritis. Future work is necessary to replicate these findings in more robust studies.

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Fruit juice consumption is associated with improved nutrient adequacy in children and adolescents: the National Health and Nutrition Examination Survey (NHANES) 2003–2006

Public Health Nutrition ◽

10.1017/s1368980012000031 ◽

2012 ◽

Vol 15 (10) ◽

pp. 1871-1878 ◽

Cited By ~ 19

Author(s):

Carol E O'Neil ◽

Theresa A Nicklas ◽

Michael Zanovec ◽

Ronald E Kleinman ◽

Victor L Fulgoni

Keyword(s):

Children And Adolescents ◽

National Health ◽

Fruit Juice ◽

Secondary Analysis ◽

Nutrition Examination Survey ◽

Adequate Intake ◽

Cross Sectional ◽

Dietary Adequacy ◽

Nutrient Adequacy ◽

Health And Nutrition

AbstractObjectiveTo examine the contribution of 100 % fruit juice (FJ) consumption to dietary adequacy of shortfall nutrients by children and adolescents.DesignCross-sectional.SettingSecondary analysis of data from the 2003–2006 National Health and Nutrition Examination Survey (NHANES).SubjectsChildren and adolescents aged 2–18 years (n 7250). Usual intake, determined from two 24 h dietary recalls, was calculated using the National Cancer Institute method. The population was dichotomized into consumers or non-consumers of 100 % FJ. The age/gender-specific percentage of the two consumption groups with intakes less than the Estimated Average Requirement or that exceeded the Adequate Intake for selected nutrients was determined. A Z-statistic for differences in population proportions was used to determine significance (P < 0·05).ResultsChildren aged 2–5 years had the highest percentage of 100 % FJ consumers (71·1 %), followed by children aged 6–12 years (57·0 %) and adolescents aged 13–18 years (44·5 %). Compared with 100 % FJ consumers, a significantly higher percentage of non-consumers had intakes below the Estimated Average Requirement for vitamin A (24·4 (se 2·5) % v. 42·2 (se 2·5) %), vitamin C (0·1 (se 0·2) % v. 38·9 (se 4·1) %), folate (8·8 (se 1·5) % v. 22·1 (se 2·4) %), P (11·6 (se 2·1) % v. 21·3 (se 2·6) %) and Mg (25·8 (se 1·7) % v. 46·1 (se 2·0) %). A greater percentage of 100 % FJ consumers exceeded the Adequate Intake for K (2·4 (se 0·5) v. 0·5 (se 0·2) %) compared with non-consumers.ConclusionsConsumption of 100 % FJ is associated with improved nutrient adequacy and can contribute to a healthy diet.

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