scholarly journals Pathological discrepancy between colposcopic directed cervical biopsy and conisation results: A five years experience of a single center in Turkey

2019 ◽  
Vol 35 (6) ◽  
Author(s):  
Hüseyin Aydoğmuş ◽  
Serhat Sen ◽  
Serpil Aydogmus
Keyword(s):  
Treatment Strategies ◽  
Tertiary Hospital ◽  
Single Center ◽  
Cervical Lesions ◽  
Creative Commons ◽  
In Situ Carcinoma ◽  
Cervical Biopsy ◽  
And Training ◽  
Open Access Article

Objective: To analyze the clinical outcomes and treatment strategies of patients who underwent conisation in a tertiary hospital clinic Methods: The study was designed as a retrospective cohort study. Retrospective data’s of 176 patients who underwent conisation due to detection of dysplasia via colposcopic biopsy or cytology-histology discrepancy between 2012 and 2017 were collected. Colposcopy guided biopsies were performed according to HPV positivity and/or abnormal smear results in Izmir Katip Celebi University Ataturk Research and Training Hospital. Results: Indications for colposcopic biopsies were HPV positivity in 51 patients (29.1%), abnormal smear results in 125 patients (70.9 %). Distribution of abnormal smear results were ASCUS, ASC-H, LSIL, HSIL in 6 (4.8 %), 21 (16.8 %), 24 (19.2%), 74 (59.2%) patients respectively. According to biopsy results, 8 patients (4.4 %) showed no dysplasia where two (1.1%) and 162 (91.5 %) patients were with LSIL and HSIL respectively. Only two were diagnosed with in situ carcinoma. Among 162 patients with HSIL in colposcopic biopsy, 45 showed no dysplasia where four were diagnosed with invasive carcinoma. Conclusions: To detect high grade cervical lesions colposcopy guided biopsy is gold standard. Although cone biopsy should be performed related to severity of dysplasia in order to sustain the diagnosis and treatment. Contradictory results between colposcopic and cone biopsies should be considered during decision-making process. doi: https://doi.org/10.12669/pjms.35.6.408 How to cite this:Aydogmus H, Sen S, Aydogmus S. Pathological discrepancy between colposcopic directed cervical biopsy and conisation results: A five years experience of a single center in Turkey. Pak J Med Sci. 2019;35(6):1627-1630. doi: https://doi.org/10.12669/pjms.35.6.408 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals A comparison of ketamine-midazolam combination and propofol-fentanyl combination on procedure comfort and recovery process in pediatric colonoscopy procedures

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Sedat Saylan ◽  
Ulas Emre Akbulut
Keyword(s):  
Original Work ◽  
Recovery Process ◽  
Tertiary Hospital ◽  
Sedation Score ◽  
Combination Group ◽  
Efficacy And Safety ◽  
Diagnostic Colonoscopy ◽  
Creative Commons ◽  
Open Access Article ◽  
Pediatric Colonoscopy

Objective: To compare the efficacy and safety of midazolam-ketamine combination versus fentanyl-propofol combination in pediatric diagnostic colonoscopy. Methods: This is a retrospective study of 68 children undergoing diagnostic gastroenterology with midazolam-ketamine combination (Group-K) or with fentanyl-propofol combination (Group-P) in the pediatric gastroentology department at a Turkish tertiary hospital between January 2015 and June 2017. An intravenous midazolam was administered one minute before ketamine administration in Group K. Intravenous fentanyl was given to Group P, followed by intravenous propofol. Results: There were statistically no significant differences between the groups as for age, gender, weight, duration of colonoscopy and complications observed during procedure. Ramsay sedation score was significantly higher in Group K. Recovery time and the rate of complications during the recovery of Group-K (23 patients, 65.7%) was significantly higher than that of Group P (8 patients, 24.2%) (p= 0.001). Conclusions: Colonoscopy procedures can be quite comfortable in children when using the midazolam-ketamine combination. However, adverse effects related to ketamine were observed during recovery. doi: https://doi.org/10.12669/pjms.37.2.2787 How to cite this:Saylan S, Akbulut UE. A comparison of ketamine-midazolam combination and propofol-fentanyl combination on procedure comfort and recovery process in pediatric colonoscopy procedures. Pak J Med Sci. 2021;37(2):---------. doi: https://doi.org/10.12669/pjms.37.2.2787 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Comparison of performance of medical students between two teaching modalities “Flip the classroom” and traditional lectures: A single center educational interventional study

2020 ◽  
Vol 36 (5) ◽  
Author(s):  
Fadwa Taher ◽  
Bayan Hafiz ◽  
Taghreed Alnajjar ◽  
Bayan Almehmadi ◽  
Bayan Besharah ◽  
...  
Keyword(s):  
Medical Students ◽  
Obstetrics And Gynecology ◽  
Single Center ◽  
Interventional Study ◽  
Creative Commons ◽  
Final Performance ◽  
Traditional Lectures ◽  
Teaching Modality ◽  
Students Satisfaction ◽  
Open Access Article

Objectives: This study aims to compare the students’ performance in Obstetrics and Gynecology by using two teaching modalities, i.e., Flip the classroom (FTC) compared to Traditional lectures (TL) among final year medical students and assessment of the students’ satisfaction towards FTC as learning modality. Methods: An educational interventional study was conducted on 136 females final year medical students at Umm Al-Qura University, Makkah, Saudi Arabia from September to December; 2017. Out of 40 core topics of Obstetrics and Gynecology, eight were chosen for FTC and eight for TL. The performance in each teaching modality was assessed by comparing the score of the students in multiple choice question (MCQ) and objective structured clinical examination (OSCE) in the final examination. The final performance was compared between the FTC and TL selected topics. The data was analyzed by using SPSS version 16 (SPSS Inc., Chicago, IL, USA). Results: MCQ and OSCE grades of students (n=136) were significantly higher in FTC versus TL topics, i.e., mean ± standard deviation (13.4 ± 2.7 vs. 12.3 ± 2.4; p < 0.001) and (33.9 ± 4.3 vs. 30.4 ± 4.7; p < 0.001), respectively. Almost 60% of the students expressed their satisfaction with FTC modality. Conclusion: Scores were significantly high for Flip the classroom topics compared to Traditional lectures. doi: https://doi.org/10.12669/pjms.36.5.2730 How to cite this:Tahir F, Hafiz B, Alnajjar T, Almehmadi B, Besharah B, Gari A, et al. Comparison of performance of medical students between two teaching modalities “Flip the classroom” and traditional lectures: A single center educational interventional study. Pak J Med Sci. 2020;36(5):---------. doi: https://doi.org/10.12669/pjms.36.5.2730 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Emphysematous Pyelonephritis: A single center review

2019 ◽  
Vol 36 (ICON-Suppl) ◽  
Author(s):  
Albeerdy Mohammad Irfaan ◽  
Nadeem Ahmed Shaikh ◽  
Anila Jamshaid ◽  
Abdul Hafeez Qureshi
Keyword(s):  
Case Series ◽  
Poor Response ◽  
Single Center ◽  
Emphysematous Pyelonephritis ◽  
Traditional Management ◽  
Creative Commons ◽  
Intravenous Antibiotics ◽  
Special Supplement ◽  
Life Threatening ◽  
Open Access Article

Background and Objective: Emphysematous pyelonephritis (EPN) is a rare, life-threatening necrotizing renal parenchymal infection. Traditional management of EPN with nephrectomy had a mortality of 40-50%. The purpose of this case series was to assess the management, biochemical factors, and outcome of EPN patients. Methods: In this retrospective study, patients admitted to The Indus Hospital, Karachi with a diagnosis of EPN from January 2010 to February 2019, were grouped according to the Huang Tseng Classification (HTC). Their biochemical parameters, sensorium states and outcomes were recorded and analysed. Results: Twenty patients were reviewed (9 males). No mortality was recorded. 11 patients (55%) were treated conservatively with only intravenous antibiotics and eight patients underwent an intervention: minimally invasive with drain placement in six patients, and invasive in four patients (two underwent subsequent nephrectomy, and two patients had nephrectomy only). One patient left against medical advice. All patients had decreased serum creatinine levels and total leucocyte counts on discharge. Conclusion: EPN can be successfully managed conservatively for HTC Grade-1 and 2. Conservative treatment may be tried in higher grades, but poor response should lead to prompt escalation of treatment. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1728 How to cite this:Irfaan AM, Shaikh NA, Jamshaid A, Qureshi AH. Emphysematous Pyelonephritis: A single center review. Pak J Med Sci. Special Supplement ICON 2020. 2020;36(1):S83-S86 doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1728 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Risk Assessment of Healthcare Workers at the Frontline against COVID-19

2020 ◽  
Vol 36 (COVID19-S4) ◽  
Author(s):  
Saqib Ali ◽  
Sara Noreen ◽  
Imran Farooq ◽  
Amr Bugshan ◽  
Fahim Vohra
Keyword(s):  
Risk Assessment ◽  
Healthcare Workers ◽  
Protective Equipment ◽  
The Novel ◽  
Creative Commons ◽  
Global Pandemic ◽  
Novel Coronavirus ◽  
Major Factors ◽  
And Training ◽  
Open Access Article

The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Healthcare workers (HCWs) are on the frontline of treating patients infected with COVID-19. However, data related to its infection rate among HCWs are limited. The aim was to present evidence associated with the number of HCWs being infected with COVID-19 from most viral affected countries (Italy, China, United States, Spain, and France). Furthermore, we looked into the reasons for HCWs COVID 19 infections and strategies to overcome this problem. Early available evidence suggested that HCWs are being increasingly infected with the novel infection ranging from 15% to 18% and in some cases up to 20% of the infected population. Major factors for infection among HCWs include lack of understanding of the disease, inadequate use and availability of Personal Protective Equipment (PPE), uncertain diagnostic criteria, unavailability of diagnostic tests and psychological stress. Therefore the protection of HCWs by authorities should be prioritized through education and training, the readiness of staff, incentives, availability of PPEs, and psychological support. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2790 How to cite this:Ali S, Noreen S, Farooq I, Bugshan A, Vohra F. Risk Assessment of Healthcare Workers at the Frontline against COVID-19. Pak J Med Sci. 2020;36(COVID19-S4):---------. doi: https://doi.org/10.12669/pjms.36.COVID19-S4.2790 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Not All Cases of Mammary Paget’s Disease are Cytokeratin-7 Positive: A Challenging Diagnosis!

2021 ◽  
pp. 106689692110029
Author(s):  
Kerschen Anja ◽  
Dano Hélène ◽  
Van Eeckhout Pascal ◽  
Marot Liliane ◽  
Van Bockstal Mieke
Keyword(s):  
Present Report ◽  
Paget’S Disease ◽  
Growth Factor Receptor ◽  
Punch Biopsy ◽  
Paget's Disease ◽  
Cytokeratin 7 ◽  
In Situ Carcinoma ◽  
Epidermal Growth ◽  
Mammary Paget’S Disease

Mammary Paget’s disease accounts for 1% to 3% of all breast tumors and manifests as a chronic eczematous lesion of the areolar skin. It can occur without any underlying neoplasia or can be present in association with an underlying invasive and/or in situ carcinoma of the breast. The present report describes a challenging nipple punch biopsy showing an infiltration of the lower third to two-thirds of the epidermis by large, ovoid, neoplastic cells. The morphology was consistent with mammary Paget's disease, although immunohistochemistry for cytokeratin-7 (CK7) was repeatedly negative. This resulted in an initial misdiagnosis and, subsequently, a delay in the patient's follow-up. Additional immunohistochemistry for GATA binding protein 3 (GATA3) and human epidermal growth factor receptor 2 (HER2), as well as a second opinion of a breast pathologist, resulted in the diagnosis of mammary Paget's disease. The aim of this article is to raise awareness among pathologists and prevent them from misdiagnosing CK7-negative Paget disease of the breast.

scholarly journals The Vocational School of Sintra and Its Contribution to Heritage Education

Heritage ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 466-478
Author(s):  
Ana Mafalda Cardeira ◽  
Marta Frade
Keyword(s):  
Cultural Heritage ◽  
Educational System ◽  
Analytical Methods ◽  
Vocational School ◽  
Work Related ◽  
Heritage Education ◽  
12Th Grade ◽  
And Training

This paper aims to share the experience acquired with students of the 3rd year (namely the 12th grade of the Portuguese educational system) at the Vocational School for the Recovery of Heritage of Sintra in the Course of Studies for Conservation and Restoration Assistants in the field of Plaster Restoration, in the classes of Work-Related Training and Analytical Methods of Examination and Laboratory Analysis, by carrying out theoretical-practical work and training in a work context specifically focused on Portuguese heritage, demonstrating how practical classes motivate students and prepare them for future professional work. This vocational course helps students to reflect and question themselves on the role of “looking” at heritage. Thus, its cross information, both interdisciplinary and from the historical-artistic context of the monument, will provide a better perspective over its materiality and its use. In situ learning awakens students to the reality of work. The notion that they are helping to maintain the memory of ancestors credits them and gives them confidence in their work. After presenting their Final Year Projects, they look at heritage with a more awakened vision. With this, they have the perception that they have contributed to the reconstruction of memory, their cultural heritage.

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