scholarly journals Comparison of choroidal thickness in eyes of diabetic patients with eyes of healthy individuals using optical coherence tomography in a tertiary care hospital

2021 ◽  
Vol 38 (1) ◽  
Author(s):  
Hafsa Hassan ◽  
Alyscia Cheema ◽  
Muhammad Ali Tahir ◽  
Hina Nasreen Nawaz
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Choroidal Thickness ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
P Value ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Optical Coherence ◽  
Healthy Individuals

Objectives: To compare the choroidal thickness in eyes of diabetic patients with eyes of age matched controls using optical coherence tomography in a tertiary care hospital. Methods: This Cross sectional study was conducted at the Department of Ophthalmology, Jinnah Postgraduate Medical Centre Karachi, for six months from13thJanuary 2020 to13thJuly 2020. The study group comprised of 44 patients with 88 eyes. Patients who fulfill the inclusion criteria that is age ranging from 35 to 80years, either gender, known case of diabetes mellitus and having any type of diabetic retinopathy (HbA1c >7), non-diabetic healthy individuals (HbA1c <7) and those giving informed consent were included in the study. However, patients having active ocular infections, history of myocardial infarction, stroke, uveitis, any ocular surgery, lasers, intravitreal injections, poor fundus view and not giving consent were excluded. A pre-designed proforma was filled. A baseline ocular examination was performed and choroidal thickness was assessed from retinal pigment epithelium to choroid sclera junction in diabetic and healthy participants of the study group using high resolution Swept source OCT (DRI-OCT-2 Triton; Topcon). Results: The average age of the patients was 39.41±15.95 years. According to our study mean central subfoveal choroidal thickness in diabetic eyes was 268.5 ± 66.22 (95% CI 240 – 297) and in non-diabetic healthy participants it was 339.3 ± 71.49 (95% CI 308 – 369) with a p-value of 0.001. However, average choroidal thickness was 261.8 ± 61.93 (95% CI 235 – 288) and 336.0 ± 74.35 (95% CI 304 – 367) in diabetic and non-diabetic healthy population with a p-value of 0.001. Choroidal thickness comparison between gender in diabetic and non-diabetic population also showed similar trend. Conclusion: In this study, mean central choroidal thickness as well as average choroidal thickness was significantly reduced in eyes having diabetic retinopathy as compared to participants with non-diabetic healthy eyes. These findings indicate that changes in choroid may be a probable route in the pathogenesis of diabetic retinopathy. doi: https://doi.org/10.12669/pjms.38.1.4443 How to cite this:Hassan H, Cheema A, Tahir MA, Nawaz HN. Comparison of choroidal thickness in eyes of diabetic patients with eyes of healthy individuals using optical coherence tomography in a tertiary care hospital. Pak J Med Sci. 2022;38(1):---------.  doi: https://doi.org/10.12669/pjms.38.1.4443 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals EVALUATION OF CHOROID THICKNESS CHANGES AFTER UNEVENTFUL PHACOEMULSIFICATION SURGERY USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AT A TERTIARY CARE EYE HOSPITAL

2022 ◽  
Vol 71 (6) ◽  
pp. 2202-06
Author(s):  
Aisha Rafique ◽  
Omar Zafar ◽  
Summaya Khan ◽  
Hassaan Javaid
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Choroidal Thickness ◽  
Tertiary Care ◽  
Armed Forces ◽  
Early Postoperative Period ◽  
Spectral Domain ◽  
P Value ◽  
Optical Coherence ◽  
Thickness Change

Objective: To analyze the effects of uneventful phacoemulsification surgery on choroidal thickness using spectral domain optical coherence tomography. Study Design: Prospective comparative study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jun 2018 to Jun 2019. Methodology: In this prospective study, 300 eyes of 300 patients undergoing phacoemulsification surgery were included. All patients underwent detailed ophthalmologic examination, including measurement with optical biometry, intraocular pressure and choroid thickness. The choroidal thickness was measured perpendicularly at the fovea using spectral domain optical coherence tomography preoperatively and 1 month postoperatively. Changes in intraocular pressure and choroid thickness after surgery were evaluated. Results: There was a statistically significant increase in the choroid thickness in early postoperative period (p-value <0.01). This increment was prominent in sub foveal regions. The intraocular pressure decreased significantly 1 month after surgery (p-value <0.01). The change in intraocular pressure was correlated with the choroid thickness change at sub foveal region. Conclusion: Uncomplicated phacoemulsification induces non-pathologic increase in sub-foveal choroid thickness probably due to the inflammatory insult of the surgery. Long-term follow-up of eyes having phacoemulsification surgery may provide further insight into the effects of cataract surgery on the choroid.

“Filling the Void in the Web Space”- Microbiological Perspective of Toe Web Space Infections in a Tertiary Care Hospital

2017 ◽  
Vol 2 (09) ◽  
Author(s):  
Dr. Anjana Gopi ◽  
Dr. Faiza Samreen ◽  
Dr. Swati Jain ◽  
Dr. Madhulatha C.K.
Keyword(s):  
Tertiary Care Hospital ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
P Value ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Bacterial Isolates ◽  
Broth Microdilution ◽  
Broth Microdilution Method ◽  
Web Space

Toe web space infections are the most common superficial dermatoses of the feet. They are often unnoticed and progress to cause discomfort. There is lack of enough evidence on the microbiological profile and antifungal susceptibility pattern. Settings and Design: A prospective study was conducted between August 2015 to February 2017 in the Department of Microbiology at a tertiary care hospital. Methods and Material: 200 samples were collected from interdigital spaces of Dermatology outpatients and inpatients. Bacterial and fungal pathogens were isolated and identified using conventional laboratory techniques. Antifungal susceptibility testing was done to determine the Minimum inhibitory concentration (MIC) by E-test. A small representative sample of Fusarium isolates were subjected to speciation by PCR and their MIC was determined by broth microdilution method for comparison. Statistical analysis used: p value was determined by Chi square test using SPSS software. Results: Our study demonstrated a male preponderance of 59 %, mostly between 41 to 50 years. Both the feet were affected in 43/48 (89.5 %) of the diabetic patients, the fourth web space being commonly involved. 198/200 (99%) of the samples were positive for either bacterial or fungal growth. There were a total of 156 fungal and 204 bacterial isolates. Out of 156 fungal isolates, Candida spp 62 (39.7 %) and Fusarium spp 50 (32 %) were the most common isolated yeast and mould respectively and 38 (24.3 %) dermatophyte species were isolated. Results of E-test and broth microdilution were comparable. Voriconazole and amphotericin B had lower MIC. Out of 204 bacterial isolates, Staphylococcus aureus 56 (27.4 %) and Pseudomonas aeruginosa 44 (21.5 %) were the most common isolates. Conclusions: A good microbiological diagnosis would assist in the better alleviation of the symptoms and provide accurate treatment of web space infections.

scholarly journals Effect of high myopia on macular thickness: An optical coherence tomography study in a tertiary care hospital, Karnataka, India

2021 ◽  
Vol 9 (1) ◽  
pp. 17
Author(s):  
RakshaHalmuthur Venkatesh ◽  
Arathi Choudhary ◽  
MP Jayashree ◽  
HamsaDyamenahalli Surendrappa ◽  
R Divya ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Myopia ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Macular Thickness ◽  
Care Hospital ◽  
Optical Coherence

scholarly journals Vision-threatening diabetic retinopathy necessitating vitrectomy in a tertiary care hospital in coastal Karnataka, South India

2020 ◽  
Vol 17 (1) ◽  
pp. 101-107
Author(s):  
Narasimha Vasista Reddy ◽  
Yogish Subraya Kamath ◽  
Lavanya G. Rao ◽  
Krishna Addoor Rao ◽  
Shailaja Bhat Shenoy ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Cross Sectional ◽  
Screening Programs ◽  
Patients With Diabetes ◽  
Advanced Stages

Background: The proportion of diabetic patients having vision-threatening diabetic retinopathy and those needing to undergo vitrectomy was documented. Methods: A cross-sectional observational study was conducted at a tertiary care hospital in coastal Karnataka, South India. All patients with diabetes mellitus visiting the ophthalmology department in the study period were screened for retinopathy, and the data regarding the presence of maculopathy and proliferative retinopathy were included as vision-threatening retinopathy. Results: Of the 1,435 diabetic patients included, 38.4% had retinopathy changes due to diabetes, with 8.71% having vision-threatening retinopathy and 1.81% needing vitrectomy. Conclusion: Although the proportion of vision-threatening retinopathy is small, the rapidly increasing diabetic population requires the setting up of more resources for tackling this condition, at least at the tertiary levels of the health-care system. However, considering the increased human and economic resources involved in setting up vitrectomy units, more emphasis on strengthening screening programs for early detection and referral to reduce the progression of retinopathy to advanced stages would be appropriate.

scholarly journals Vitreo-macular Interface Abnormalities in Diabetic and Non-Diabetic Patients Using Optical Coherence Tomography

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Uzma Hamza ◽  
Waqas Asghar ◽  
Qasim Lateef Chaudhry ◽  
Muhammad Hassaan Ali ◽  
Sana Jahangir
Keyword(s):  
Optical Coherence Tomography ◽  
Tertiary Care ◽  
Posterior Vitreous Detachment ◽  
Age Groups ◽  
P Value ◽  
Diabetic Patients ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Hospital Patients ◽  
Vitreomacular Interface

Purpose: To study the frequency of vitreomacular interface abnormalities (VIAs) in diabetic and non-diabeticpatients presenting in a tertiary care hospital.Study Design: Comparative cross-sectional study.Place and Duration of Study: Jinnah hospital, Lahore from May 2013 to June 2016.Methods: The frequency of vitreomacular interface abnormalities (VIAs) was assessed among 278 patients, whopresented in outpatient department of our hospital. Patients were categorized into diabetic and non-diabeticgroups on the basis of hemoglobinHbA1c. Patients with altered macular reflex on slit lamp examination underwentspectral domain (SD) optical coherence tomography (OCT) of macula to determine VIAs.Results: There were 278 patients in the study with mean age 59.7 ± 11.7(range: 40 – 65) years and male tofemale ratio of 1:1.06. Prevalence of VIAs was observed to be higher among diabetic patients than non-diabeticsin all age groups (p-value < 0.05). Overall frequency of different VIAs was found to be 10.7% for epiretinalmembrane, 6.4% for posterior vitreous detachment, 6.1% for macular edema/macular cyst, 4.3% forvitreomacular traction, 1.8% for full thickness macular holes and 0.71% for partial thickness macular holes.Macular edema/macular cystwas the most common. VIA was more commonly observed in diabetic patients(17.2%). Except for ERM, all lesions of VIAs were significantly more prevalent in females as compared to males.Conclusion: VIAs are found in significantly larger number in diabetics compared to non-diabetic patients.Female gender with advancing age is associated with a higher frequency of VIAs.

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