scholarly journals Thoracic Splenosis - A necessary differential diagnosis for pleural based nodules with history of thoracoabdominal trauma

2022 ◽  
Vol 38 (3) ◽  
Author(s):  
Faisal Mehmood ◽  
Muhammad Murad Murtaza ◽  
Shehrbano Ali ◽  
Amna Ashraf
Keyword(s):  
Differential Diagnosis ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Medical Condition ◽  
Diagnostic Procedures ◽  
Splenic Tissue ◽  
Benign Condition ◽  
Creative Commons ◽  
History Of ◽  
Diagnostic Modalities

Thoracic Splenosis (TS) is a rare medical condition, where there is auto-transplantation of the splenic tissue in the thoracic cavity, often leading to pleural based nodules. Our patient is the first ever case of this condition in Pakistan, and underwent extensive diagnostic procedures as well as medical treatments, before receiving the diagnosis of TS. He underwent HRCT for chronic cough that revealed pleural and mediastinal nodules. This coupled with a vague mass in the testes led to the provisional diagnosis of metastasized testicular tumour, and later a diagnosis of pulmonary tuberculosis was made. However, eventually a 99mTc denatured red blood cell scan confirmed the diagnosis of TS. TS is a benign condition, whereas other causes of pleural nodules are relatively malignant, hence its diagnosis is essential in ruling out malignancies. Among the multiple invasive and non-invasive diagnostic modalities, the gold standard remains 99mTc denatured red blood cell scan, which is a sensitive test that provides an accurate diagnosis and bars the need of multiple invasive procedures. doi: https://doi.org/10.12669/pjms.38.3.4563 How to cite this:Mehmood F, Murtaza MM, Ali S, Ashraf A. Thoracic Splenosis - A necessary differential diagnosis for pleural based nodules with history of thoracoabdominal trauma. Pak J Med Sci. 2022;38(3):---------.  doi: https://doi.org/10.12669/pjms.38.3.4563 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Red Blood Cell Transfusion in the Emergency Department: An Observational Cross-Sectional Multicenter Study

2021 ◽  
Vol 10 (11) ◽  
pp. 2475
Author(s):  
Olivier Peyrony ◽  
Danaé Gamelon ◽  
Romain Brune ◽  
Anthony Chauvin ◽  
Daniel Aiham Ghazali ◽  
...  
Keyword(s):  
Emergency Department ◽  
Logistic Regression ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cross Sectional Study ◽  
Red Blood Cell Transfusion ◽  
Cross Sectional ◽  
Acute Bleeding ◽  
History Of ◽  
Rbc Transfusion

Background: We aimed to describe red blood cell (RBC) transfusions in the emergency department (ED) with a particular focus on the hemoglobin (Hb) level thresholds that are used in this setting. Methods: This was a cross-sectional study of 12 EDs including all adult patients that received RBC transfusion in January and February 2018. Descriptive statistics were reported. Logistic regression was performed to assess variables that were independently associated with a pre-transfusion Hb level ≥ 8 g/dL. Results: During the study period, 529 patients received RBC transfusion. The median age was 74 (59–85) years. The patients had a history of cancer or hematological disease in 185 (35.2%) cases. Acute bleeding was observed in the ED for 242 (44.7%) patients, among which 145 (59.9%) were gastrointestinal. Anemia was chronic in 191 (40.2%) cases, mostly due to vitamin or iron deficiency or to malignancy with transfusion support. Pre-transfusion Hb level was 6.9 (6.0–7.8) g/dL. The transfusion motive was not notified in the medical chart in 206 (38.9%) cases. In the multivariable logistic regression, variables that were associated with a higher pre-transfusion Hb level (≥8 g/dL) were a history of coronary artery disease (OR: 2.09; 95% CI: 1.29–3.41), the presence of acute bleeding (OR: 2.44; 95% CI: 1.53–3.94), and older age (OR: 1.02/year; 95% CI: 1.01–1.04). Conclusion: RBC transfusion in the ED was an everyday concern and involved patients with heterogeneous medical situations and severity. Pre-transfusion Hb level was rather restrictive. Almost half of transfusions were provided because of acute bleeding which was associated with a higher Hb threshold.

scholarly journals Butterfly vertebra: a case report

2017 ◽  
Vol 31 (1) ◽  
pp. 80-84 ◽  
Author(s):  
D. Adam ◽  
D. Iftimie ◽  
Gina Burduşa ◽  
Cristiana Moisescu
Keyword(s):  
Vertebral Fracture ◽  
Diagnostic Procedures ◽  
Spinal Pain ◽  
Benign Condition ◽  
Thoracic Spinal ◽  
Schmorl’S Nodes ◽  
History Of ◽  
Epidural Fat ◽  
Vertebral Bodies ◽  
Local Examination

Abstract Background and importance: Butterfly vertebra is an uncommon congenital spinal anomaly, which can be easily mistaken for vertebral fracture, infection or tumor. Clinical presentation: We report the case of a 20-year-old male patient with a 3-year history of intermittent mid-thoracic spinal pain. Local examination showed a mild thoracic kyphoscoliosis. Neurological examination was normal. Computer tomography revealed the presence of a T6 butterfly vertebra associated with morphological anomalies in adjacent vertebral bodies and T6-T9 Schmorl’s nodes. MRI scan confirmed the diagnosis and additionally showed a mild spinal stenosis caused by apparent posterior epidural fat hypertrophy. The patient was treated with painkillers and physical therapy. Conclusion: Butterfly vertebra is a benign condition. Once diagnosed, additional diagnostic procedures are not necessary. Neurosurgeons must be aware of this congenital anomaly that should not be confused with a vertebral fracture.

Red blood cell Na content, Na, Li-countertransport, family history of hypertension and blood pressure in school children

1988 ◽  
Vol 6 (3) ◽  
pp. 227-230 ◽  
Author(s):  
Maurizio Trevisan ◽  
Pasquale Strazzullo ◽  
Francesco Paolo Cappuccio ◽  
Michele Roberto Di Muro ◽  
Stefano De Colle ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Blood Cell ◽  
School Children ◽  
Red Blood Cell ◽  
History Of ◽  
Family History Of Hypertension

GASTRIC ULCER OF THE PYLORUS SIMULATING. HYPERTROPHIC PYLORIC STENOSIS

PEDIATRICS ◽  
1950 ◽  
Vol 6 (6) ◽  
pp. 897-907
Author(s):  
ARTHUR R. C. COLE
Keyword(s):  
Differential Diagnosis ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Pyloric Stenosis ◽  
Recent Literature ◽  
Hypertrophic Pyloric Stenosis ◽  
Diagnostic Procedures ◽  
Peptic Ulcers ◽  
Infancy And Childhood ◽  
History Of

A brief review of the natural history of peptic ulcer in infancy and childhood is given. The symptomatology, differential diagnosis and diagnostic procedures are presented. The diagnosis of peptic ulcer should be considered more often in infancy and childhood and the proper diagnostic procedures instituted. A case of gastric ulcer simulating hypertrophic pyloric stenosis is presented. A summary of 31 cases with peptic ulcers found at autopsy at the Babies Hospital from January 1, 1924 to January 1, 1950 is given. From a summary of coexistent disease found in the autopsy cases at the Babies Hospital and reports from the recent literature, it would appear that diseases of the central nervous, gastrointestinal and respiratory systems are commonly present in cases which have shown peptic ulcer at autopsy.

scholarly journals Sonographic Discovery of Autotransplanted Splenic Implants in a Pregnant Patient

2018 ◽  
Vol 35 (1) ◽  
pp. 75-78
Author(s):  
Emily M. Downs ◽  
Shane Reeves
Keyword(s):  
Differential Diagnosis ◽  
Pregnant Patient ◽  
Splenic Tissue ◽  
Splenic Trauma ◽  
Sonographic Appearance ◽  
History Of

It is important to include splenic implants in the differential diagnosis of patients with a history of splenic trauma. Autotransplanted splenic implants may have a sonographic appearance similar to that of pathologies such as lymphadenopathy or carcinomatosis. This is the first known case to discuss a pregnant patient with a history of autologous autotransplanted splenic tissue, which was discovered on sonography and confirmed during the patient’s cesearean section.

scholarly journals Calcific myonecrosis: diagnostic dilemma

2018 ◽  
Vol 100 (6) ◽  
pp. e158-e160
Author(s):  
HE Matar ◽  
P Stritch ◽  
S Connolly ◽  
N Emms
Keyword(s):  
Magnetic Resonance Imaging ◽  
Differential Diagnosis ◽  
Magnetic Resonance ◽  
Malignant Tumour ◽  
Resonance Imaging ◽  
Diagnostic Dilemma ◽  
Benign Condition ◽  
Calcific Myonecrosis ◽  
History Of ◽  
Growing Mass

Calcific myonecrosis is a rare benign condition affecting mainly the muscles of a single leg compartment. It is thought to follow a history of trauma with a latent period of years. Patients present with a slowly growing mass. Differential diagnosis from a malignant tumour can be made from the history and the distinctive radiographical features of a fusiform lesion with predominantly peripheral calcifications. Magnetic resonance imaging may be necessary to confirm the diagnosis; treatment is largely symptomatic.

Red blood cell aggregability in patients with a history of leg vein thrombosis: influence of post-thrombotic treatment

1994 ◽  
Vol 88 (1) ◽  
pp. 174-179 ◽  
Author(s):  
Anne Chabanel ◽  
Marie Hélé;ne Horellou ◽  
Jacqueline Conard ◽  
Meyer M. Samama
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Vein Thrombosis ◽  
History Of

Limiting the Extent of a Delayed Hemolytic Transfusion Reaction With Automated Red Blood Cell Exchange

2013 ◽  
Vol 137 (6) ◽  
pp. 861-864 ◽  
Author(s):  
Christopher A. Tormey ◽  
Gary Stack
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Positive Antibody ◽  
Antiglobulin Test ◽  
Hemolytic Transfusion Reaction ◽  
History Of ◽  
Delayed Hemolytic Transfusion Reaction ◽  
Antibody Screen ◽  
Patient’S History ◽  
Transfusion Reactions

Delayed hemolytic transfusion reactions (DHTRs) are mediated by blood group antibodies that undergo anamnestic increases following antigen reexposure. Available options for the treatment or prophylaxis of DHTRs are limited. We report the use of automated red blood cell exchange (ARE) to limit hemolysis associated with an emerging DHTR. Following transfusion of 12 red blood cell units, a family member's comments led to the discovery of a patient's history of 4 alloantibodies (anti-E, anti-c, anti-Fya, and anti-M). Testing revealed that all 12 units were incompatible for at least 1 antigen. Six days after transfusion, the patient developed a newly positive antibody screen and direct antiglobulin test (DAT) result. To prevent further hemolysis, ARE was performed to replace incompatible red blood cells with antigen-negative units. After ARE, the patient's DAT results were negative and he was discharged without demonstrating symptoms of hemolysis. This case illustrates the use of ARE to limit hemolysis and prevent symptoms of a DHTR.

Abstract 318: Determinants of Red Blood Cell Omega-3-Fatty Acid Content in Patients With Peripheral Arterial Disease

2014 ◽  
Vol 34 (suppl_1) ◽  
Author(s):  
Emily V Nosova ◽  
Christopher D Owens ◽  
Karen C Chong ◽  
Hugh F Alley ◽  
Michael S Conte ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Peripheral Arterial Disease ◽  
Blood Cell ◽  
Fish Oil ◽  
Red Blood Cell ◽  
Arterial Disease ◽  
Omega 3 ◽  
History Of ◽  
The Mean ◽  
Peripheral Arterial

Objectives: Despite available medical therapies, patients with peripheral arterial disease (PAD) remain at high risk for cardiovascular events. n-3 polyunsaturated fatty acids (PUFAs), derived from marine sources, have been shown to improve cardiovascular mortality. The omega-3 index (O3I), a proportion of the n-3 PUFAs eicosapentanoic acid and docosahexanoic acid in the red blood cell membrane, correlates with cardiovascular risk. We sought to determine the clinical factors associated with the O3I in patients with PAD. Methods: This cross-sectional study included 111 patients, who had an ankle-brachial index of < 0.9 associated with claudication symptoms. We used linear regression to determine the association between demographic and lifestyle factors and the O3I. Results: The mean age of the cohort was 69 ± 8 years, 37% had diabetes mellitus (Hemoglobin A1c: 7 ± 1%), and 94% had smoked. The mean O3I was 5 ± 2%. Table 1 shows the variables associated with O3I in regression analyses. In a multivariate model, an independent association was maintained with increasing age, BMI, and a history of smoking and fish oil intake. Conclusions: In a cohort of patients with PAD, older age, elevated BMI, and prior fish oil supplementation predicted a higher O3I. A history of smoking correlated with a lower O3I. Our findings suggest that targeting nutrition and tobacco use with therapeutic interventions has potential to reduce cardiovascular risk among PAD patients.

Sign in / Sign up

Export Citation Format

Share Document