scholarly journals Immunohistochemical Study of the Laminin α5 Chain and Its Specific Receptor, Basal Cell Adhesion Molecule (BCAM), in both Fetal and Adult Rat Pituitary Glands

2018 ◽  
Vol 51 (5) ◽  
pp. 145-152
Author(s):  
Morio Azuma ◽  
Takehiro Tsukada ◽  
Takeshi Inagaki ◽  
Fujianti Casmad ◽  
Depicha Jindatip ◽  
...  
2000 ◽  
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pp. 1047-1053 ◽  
Author(s):  
Margarete Schön ◽  
Viktor Hogenkamp ◽  
B. Gregor Wienrich ◽  
Michael P. Schön ◽  
C. Eberhard Klein ◽  
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2014 ◽  
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pp. 11512-11521 ◽  
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Vicky Chaar ◽  
Sandrine Laurance ◽  
Claudine Lapoumeroulie ◽  
Sylvie Cochet ◽  
Maria De Grandis ◽  
...  

2011 ◽  
Vol 286 (27) ◽  
pp. 24385-24393 ◽  
Author(s):  
Martin Kriebel ◽  
Jennifer Metzger ◽  
Sabine Trinks ◽  
Deepti Chugh ◽  
Robert J. Harvey ◽  
...  

Cell adhesion molecules regulate synapse formation and maintenance via transsynaptic contact stabilization involving both extracellular interactions and intracellular postsynaptic scaffold assembly. The cell adhesion molecule neurofascin is localized at the axon initial segment of granular cells in rat dentate gyrus, which is mainly targeted by chandelier cells. Lentiviral shRNA-mediated knockdown of neurofascin in adult rat brain indicates that neurofascin regulates the number and size of postsynaptic gephyrin scaffolds, the number of GABAA receptor clusters as well as presynaptic glutamate decarboxylase-positive terminals at the axon initial segment. By contrast, overexpression of neurofascin in hippocampal neurons increases gephyrin cluster size presumably via stimulation of fibroblast growth factor receptor 1 signaling pathways.


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