Analysis of Chemical Constituents of the Volatile Oils from Nardostachys Chinensis Batal by GC-MS and the Study of Antimicrobial Activities

Detailed chemical constituents of essential oil from the Pterocephalus hookeri leaves and its antimicrobial activities were investigated in this study. The essential oil, obtained by hydrodistillation, was characterized by gas chromatography-flame ionization detection and gas chromatography-mass spectrometry analyses. Among the 90 identified compounds, hexadecanoic acid (21.27%), phytol (8.03%), furfural (7.08%), oleic acid (5.25%), and phytone (4.56%) were the major components. In the antimicrobial assay, the essential oil showed strong inhibitory activities against Escherichia coli, Candida albicans, and Staphylococcus aureus with minimum inhibitory concentration values of 31.3, 62.5, and 125 µg/mL, respectively. To our knowledge, this is the first report concerning chemical composition and antimicrobial activities of the essential oil from Pterocephalus hookeri.

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Comparison of chemical constituents and antimicrobial activities of three essential oils from three different brands' clove samples collected from Gulf region

Asian Pacific Journal of Tropical Disease ◽

10.1016/s2222-1808(14)60570-3 ◽

2014 ◽

Vol 4 (4) ◽

pp. 262-268 ◽

Cited By ~ 24

Author(s):

Mohammad Amzad Hossain ◽

Saliha Rashid AL Harbi ◽

Afaf Mohammed Weli ◽

Qasim Al-Riyami ◽

Jamal Nasser Al-Sabahi

Keyword(s):

Essential Oils ◽

Chemical Constituents ◽

Antimicrobial Activities ◽

Gulf Region

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Chemical Constituents and Biological Activities of Cordia Myxa L.: A Review

The Natural Products Journal ◽

10.2174/2210315511666210210161803 ◽

2021 ◽

Vol 11 ◽

Author(s):

Varinder Singh ◽

Ankita Sood ◽

Simran Pruthi ◽

Manjinder Singh ◽

Balraj Saini ◽

...

Keyword(s):

Biological Activities ◽

Chemical Constituents ◽

Antimicrobial Activities ◽

Functional Health ◽

Future Research ◽

Health Food ◽

Toxicological Evaluation ◽

Cordia Myxa ◽

Chronic Fever ◽

Tract Infections

Background: Cordia myxa L. (CM) is a valuable ethnomedicinal plant from Boraginaceae family. Traditionally, CM parts especially fruits and leaves are used in chest and urinary tract infections, diarrhoea, dysentery, tuberculosis, liver and spleen disorders, chronic fever, malaria etc. Objective: Despite of known importance and uses, CM has gained relatively less attention of researchers and concise reviews revealing the medicinal potential of CM are scanty. The present review summarizes the chemical constituents and biological activities of CM and aims to stimulate future research to develop it as a functional health food. Results: Analysis of literature on CM showed that its fruits are a rich source of nutrients and are frequently employed in wide ailments such as urinary and respiratory tract infections, chronic fever, liver disorders, asthma, used as anthelmintic, diuretic, expectorant and purgative. Scientific studies have shown the antidiabetic, analgesic, anti-inflammatory, anti-cancer, antioxidant, antiplasmodial, hepatoprotective, hypotensive, antiulcer and antimicrobial activities of CM. More than 45 compounds belonging to carbohydrates, steroids, carotenoids, phenols, flavonoids and alkaloids have been reported from various parts of CM. Conclusion: Systematic preclinical studies support the traditional claims of CM. The analysis of available literature showed that CM could be developed as a drug. Further, studies such as detailed pharmacological and toxicological evaluation, isolation of bioactive compounds, quantitative phytochemistry and structure activity relationship are scanty and thus, crucial to be addressed for uplifting the scientific value of this revered medicinal plant.

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Food Products with High Antioxidant and Antimicrobial Activities and Their Sensory Appreciation

Applied Sciences ◽

10.3390/app12020790 ◽

2022 ◽

Vol 12 (2) ◽

pp. 790

Author(s):

Mihaela Adriana Tița ◽

Maria Adelina Constantinescu ◽

Ovidiu Tița ◽

Endre Mathe ◽

Loreta Tamošaitienė ◽

...

Keyword(s):

Dairy Product ◽

Control Sample ◽

Antimicrobial Properties ◽

Antimicrobial Activities ◽

Point Of View ◽

Volatile Oils ◽

Textural Characteristics ◽

Fermented Dairy Product ◽

Fermented Dairy ◽

Antioxidant And Antimicrobial Activities

(1) Background: The demand for healthy and nutritious food is growing worldwide. Fermented dairy products are highly valued by consumers for their health benefits. Kefir is a fermented dairy product that brings many benefits to the consumer due to its antioxidant, anticancer, antidiabetic, antihypertensive and antimicrobial properties. Extracts from various plants in the form of volatile oils have a beneficial efct on consumer health. their antioxidant and antimicrobial activities were demonstrated. (2) Methods: In the present study, the main purpose was to obtain a fermented dairy product with a high nutritional value; therefore, kefir, enriched with three types of volatile oils, namely, volatile mint oil, volatile fennel oil and volatile lavender oil, was made. The kefir samples obtained were sensory and texturally analyzed. The beneficial effect on health must also be studied in terms of the acceptability of these products by consumers from a sensory point of view. A non-numerical method based on several multi-personal approval criteria was used to interpret the results obtained in the sensory analysis. In the textural analysis, the consistency, cohesiveness and firmness of the kefir samples were analyzed. (3) Results: The samples enriched with volatile oils obtained superior results compared to the control sample in both conducted examinations. Kefir samples with volatile oils retained their sensory and textural characteristics for a longer time during storage. (4) Conclusions: The volatile oils added to kefir positively influenced the sensory and textural characteristics of the finished product.

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A preliminary study on the antimicrobial activities and gas chromatography-mass spectrometry (GC-MS) analysis of the ethyl acetate extract of Dennettia tripetala G. Baker seeds

Bio-Research ◽

10.4314/br.v18i1.4 ◽

2020 ◽

Vol 18 (1) ◽

pp. 1094-1102

Author(s):

UF Babaiwa ◽

SO Eraga ◽

EO Ojugo ◽

O Erharuyi ◽

JO Akerele

Keyword(s):

Antimicrobial Activity ◽

Ethyl Acetate ◽

Ethyl Acetate Extract ◽

Chemical Constituents ◽

Antimicrobial Activities ◽

Fatty Acid Esters ◽

Gas Chromatography Mass Spectrometry ◽

Diffusion Method ◽

Traditional Use ◽

Dennettia Tripetala

The study investigated the antimicrobial properties and the chemical composition of ethyl acetate extract of Dennettia tripetala (pepper fruit) seeds. Crude extract obtained by maceration of pulverized seeds in ethyl acetate was evaluated for antimicrobial activity against Escherichia coli, Staphylococcus aureus, Klebsiella aerogenes, Pseudomonas aeruginosa, Bacillus subtilis, Candida albicans and Aspergillus niger using standard agar-well diffusion method. GC-MS method was used to determine the chemical constituents of the extract. The extract was oily, yellowish-brown with a yield of 1.66 % and had activity against most of the test microorganisms, with inhibition zone diameters ranging between 10 to 25 mm. About 41 chemical constituents were present in the extract with formic acid methyl esters and fatty acids accounting for 57.23 and 18.49 % respectively. Ethyl acetate extract of Dennettia tripetala seeds possessed antimicrobial activity against bacteria but not fungi. The observed activity may be due to the presence of formic and fatty acid esters in the seed. The study further established a scientific proof for the traditional use of Dennettia tripetala seed extracts in treating microbial infections.

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Chemical Constituents from Vitex negundo (Linn.) of Nepalese Origin

Scientific World ◽

10.3126/sw.v6i6.2630 ◽

1970 ◽

Vol 6 (6) ◽

pp. 27-32 ◽

Cited By ~ 16

Author(s):

LM Gautam ◽

SL Shrestha ◽

P Wagle ◽

BM Tamrakar

Keyword(s):

Chemical Constituents ◽

Antimicrobial Activities ◽

Vitex Negundo ◽

E Coli ◽

Phytochemical Investigation ◽

Scientific World ◽

Pure Compounds ◽

Rf Values ◽

Control Pain ◽

Mild Acid

Vitex negundo Linn., belonging to family Verbenaceae, is an aromatic shrub distributed in lower part of Himalayan region of Nepal. In the ayurvedic system of medicine, it is used to control pain, inflammation and other related diseases. It contains many polyphenolic compounds, terpenoids, glycosidic iridoids and alkaloids. Bioactivity guided phytochemical investigation of methanolic extract of leaves of Vitex negundo resulted in the isolation of eight compounds under silicagel VLC, CC and preparative TLC. They were identified as negundoside, agnuside, vitegnoside, 7,8 dimethyl herbacetin 3-rhamnoside, 5,3'-dihydroxy-7,8,4'-trimethoxy flavanone, 5-hydroxy-3,6,7,3',4'-pentamethoxy flavone, 5,7 dihydroxy- 6,4' dimethoxy flavonone, and 5 hydroxy-7,4' dimethoxy flavone. The structures of pure compounds were elucidated by MP, Rf values, Co- TLC, Colour reactions (Cerric sulphate spray), mild acid hydrolysis and spectroscopic methods (Mass, UV, IR, 1H, 13C and 2 D NMR). All the isolated compounds were evaluated for their antimicrobial activities. They were found to have significant antibiotic activity against Bacillus subtilis, Staphylococcus aureus, Micrococcus pyogenes, Pseudomonas aeruginosa and E. coli. The compounds vitegnoside, and 7, 8 dimethyl herbacetin 3-rhamnoside have MIC 6.25mg/ml. Keywords: Vitex negundo; Verbenaceae; Chemical constituents; Bioassay; Analysis. DOI: 10.3126/sw.v6i6.2630 Scientific World, Vol. 6, No. 6, July 2008 27-32

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CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL EFFECTS OF LEPIDIUM SATIVUM-A REVIEW

International Journal of Current Pharmaceutical Research ◽

10.22159/ijcpr.2019v11i6.36338 ◽

2019 ◽

pp. 1-10 ◽

Cited By ~ 1

Author(s):

ALI ESMAIL AL-SNAFI

Keyword(s):

Amino Acids ◽

Uric Acid ◽

Chemical Constituents ◽

Sinapic Acid ◽

Lepidium Sativum ◽

Protective Effects ◽

Pharmacological Effects ◽

Bioactive Constituents ◽

Volatile Oils ◽

Current Review

Lepidium sativum contained many bioactive constituents included cardiac glycoside, alkaloids, phenolic, flavonoids, cardiotonic glycosides, coumarins, glucosinolates, carbohydrates, proteins and amino-acids, mucilage, resins, saponins, sterols, tannins, volatile oils, triterpene, sinapic acid and uric acid. The pharmacological investigation revealed that Lepidium sativum possessed antimicrobial, antidiabetic, antioxidant, anticancer, reproductive, gastrointestinal, respiratory, anti-inflammatory, analgesic, antipyretic, cardiovascular, hypolipidemic, diuretic, central nervous, fracture healing and protective effects. The current review discussed the chemical constituents and pharmacological effects of Lepidium sativum.

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Comparison of the Composition of Three Mahonia Plants Based on GC-MS Analysis

E3S Web of Conferences ◽

10.1051/e3sconf/201913101125 ◽

2019 ◽

Vol 131 ◽

pp. 01125

Author(s):

Haitao Guo ◽

Xiaoming Xue ◽

Chenghui Nan ◽

Xi Liu ◽

Zehui Wang ◽

...

Keyword(s):

Plant Material ◽

Chemical Constituents ◽

Acid Amide ◽

Triphenylphosphine Oxide ◽

Gas Chromatography Mass Spectrometry ◽

Volatile Oils ◽

Stems And Leaves ◽

Main Components ◽

Mahonia Bealei ◽

Material Evidence

Plant material evidence inspection is Mahonia bealei (Fort.) Carr., Mahonia fortunei (Lindl.) and Mahonia bodinieri Gagnep. are three common medicinal plants commonly found in Mahonia. In this study, gas chromatography-mass spectrometry (GC-MS) was used to compare the chemical constituents of stems and leaves of these three plants. The results showed that 6 of the volatile oils of the three plant species contained the same chemical composition, which was neophytadiene, palmitic acid, n-dodecane, octacosane, erucamide, and vitamin E oil, but the percentage content was difference. The main components of the volatile oils of the three plant stems were different. Erucamide was only detected in Mahonia fortunei (Lindl.) Fedde, oleic acid amide only detected in Mahonia bealei (Fort.) Carr. , and oxidized cyclooctene , and four compounds such as triphenylphosphine oxide was detected in Mahonia bodinieri Gagnep. ..

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