scholarly journals Autonomic nervous system assessment in people with HIV: A cross-sectional study

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 696
Author(s):  
Martin Rosario ◽  
Maryvi Gonzalez-Sola

Background: People diagnosed with HIV may exhibit orthostatic hypotension (OH) as a result of the infection and of secondary effects of medications. Such impairments are attributed to autonomic nervous system (ANS) deficits. The purpose of this study was to assess OH during a balance sensory condition test (SCT) and evaluate the role of the cardiac autonomic system, regarding blood pressure (BP) and heart rate (HR), during this balancing task. We hypothesized that BP and heart rate would rise with an increase in postural instability, thus revealing OH. Methods: Eight individuals diagnosed with HIV were recruited from a community health center in the area of San Juan, Puerto Rico. BP and HR were measured after 5 minutes of sitting, immediately after standing up and 1 minute after this, during the SCT. A t-test was used to assess the difference between BP in sitting, BP in standing, and BP while performing the SCT. HR was also evaluated the same way. Results: There was an increase of more than 10 mmHg in systolic BP (SBP) from sitting compared to standing while performing the SCT (p≤0.01). Likewise, HR and SBP standing versus standing during the SCT increased significantly (p≤0.01).  Conclusion: The results of this study show that the ANS may be impaired in people with HIV.

2019 ◽  
Vol 11 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Burcin Karamustafaoglu Balci ◽  
Zehra Kabakci ◽  
Damla Y Guzey ◽  
Bartu Avci ◽  
Murathan Guler ◽  
...  

Introduction: Available data suggest that there is an association between endometriosis and a group of disorders including autonomic nervous system irregularities. A deeper understanding of relationship between endometriosis and autonomic nervous system is needed as it may lead to novel discoveries on the causes or consequences of endometriosis. In this study, we analyzed the prevalence of migraine in patients with endometriosis. Methods: In this cross-sectional study, medical records of women were reviewed through January 2013 to December 2017. Women with laparoscopically proven endometriosis (n = 185) were compared with those without endometriosis (n = 168). The 3-item screening questions (ID Migraine™) test was used to screen migraine. Data were analyzed using SPSS v25 (IBM Corporation). The χ2 test was used for analyzing the nominal parameters and group comparisons. Pearson χ2 was used to study the association between endometriosis and migraine. Results: The mean age was 31.86 ± 4.49 years of the endometriosis group and 28.95 ± 5.11 years of the controls (p = 0.408). The two pre-screening questions of ID Migraine test were answered positively by 86 patients of the endometriosis group (75.4%) and by 53 patients of the control group (54.6%) (p = 0.001). Of these patients, 51 (44.7% of endometriosis group) and 26 (26.8% of control group) were diagnosed as having migraine using 3-item Migraine questionnaire (p = 0.007). Conclusion: This study showed that the prevalence of migraine was significantly higher in patients with endometriosis. Because there is a strong correlation, patients with endometriosis should be screened for headache and migraine to increase the benefits of care.


PLoS ONE ◽  
2013 ◽  
Vol 8 (1) ◽  
pp. e54546 ◽  
Author(s):  
Petra Baum ◽  
David Petroff ◽  
Joseph Classen ◽  
Wieland Kiess ◽  
Susann Blüher

2020 ◽  
Vol 55 (9) ◽  
pp. 1001-1008 ◽  
Author(s):  
Kyle T. Ebersole ◽  
David J. Cornell ◽  
Robert J. Flees ◽  
Corey M. Shemelya ◽  
Sabrina E. Noel

Context Sudden cardiac deaths (SCDs) have accounted for nearly half of the line-of-duty deaths among US firefighters over the past 10 years. In 2018, 33% of all SCDs occurred after the end of a fire service call. Researchers have suggested that an imbalance in autonomic nervous system (ANS) regulation of heart rate postcall may interfere with recovery in firefighters. Objective To use heart-rate recovery (HRR) and heart-rate variability (HRV), 2 noninvasive markers of ANS function, to examine the ANS recovery profiles of firefighters. Design Cross-sectional study. Setting Firehouse and research laboratory. Patients or Other Participants Thirty-seven male career active-duty firefighters (age = 39 ± 9 years, height = 178.8 ± 5.4 cm, mass = 87.9 ± 11.2 kg). Main Outcome Measure(s) Percentage of maximal HR (%MHR) and HRV (natural log of the square root of the mean sum of the squared differences [lnRMSSD]) were collected after both submaximal and maximal exercise protocols during a 10-minute seated recovery. The HRR profiles were examined by calculating the asymptote, amplitude, and decay parameters of the monoexponential HRR curve for each participant. Results Differences in HRR parameters after 10 minutes of seated recovery were identified after submaximal versus maximal exercise (P < .001). In addition, although ANS was more suppressed after maximal exercise, HRV indicated incomplete recovery, and regardless of the test, recovery %MHR and lnRMSSD values did not return to pretest %MHR and lnRMSSD values. Conclusions Our results suggest that the ANS contributions to recovery in active-duty firefighters are exercise-intensity specific, and this is likely an important factor when establishing best-practice recovery guidelines.


Author(s):  
Juliana Leal Ribeiro Cantalino ◽  
Afonso Shiguemi Inoue Salgado ◽  
Israel Reis Santos ◽  
Luis Vicente Franco Oliveira ◽  
Claudia Santos Oliveira ◽  
...  

Introduction: To study the effect of myofascial techniques applied to the cranial regionon the behavior of autonomic nervous system (ANS), using the analyses of heart ratevariability. Method: This is a clinical trial study accomplished with 66 healthy subjects(33 male and 33 female). Myofascial techniques applied to the cranial area usingcraniosacral therapy were executed on the individuals. The Nerve-Express system, afully automated system, was used before and after the application of the techniques toquantitatively assess the autonomic function based on heart rate variability analysis. Toverify the existence of differences among the dependent variables the Wilcoxon SignedRanks Test was used and o Mann-Whitney Test was applied in order to compare theindependent variable. Results: It was observed a statistically significant increase, inthe values of parasympathetic nervous system (PSNS), after the application of thetechnique. The quantitative values of sympathetic nervous system (SNS) decreased ordid not modify in female group. This profile in female group was statistically significantalthough in the male group the miofascial mobilization did not modify the values ofSNS. The quantitative values of SNS and PSNS behaved equal relatively in both studiedgroups, not being significant statistically the difference between the male and femalegroups. Conclusion: These results suggest that the myofascial technical applied to thecranial area by craniossacral therapy is able to promote alterations in the behavior ofANS, generally, increasing PSNS and decreasing SNS.


2021 ◽  
Vol 12 ◽  
Author(s):  
Ileana Schmalbach ◽  
Benedict Herhaus ◽  
Sebastian Pässler ◽  
Sarah Runst ◽  
Hendrik Berth ◽  
...  

To foster understanding in the psychopathology of patients with anorexia nervosa (PAN) at the psychological and physiological level, standardized experimental studies on reliable biomarkers are needed, especially due to the lack of disorder-specific samples. To this end, the autonomic nervous system (ANS) response to a psychosocial stressor was investigated in n = 19 PAN (BMI: 18.7 ± 3.3 kg/m2), age, and gender-matched to n = 19 healthy controls (HC; BMI: 24.23 ± 3.0 kg/m2). For this purpose, heart rate (HR) and heart rate variability (HRV) parameters were assessed in a cross-sectional study design under two experimental conditions: (1) rest and (2) stress (Trier Social Stress Test). In addition, psychological indicators of stress were assessed. An 2 × 2 × 8 ANOVA demonstrated similar HR and HRV patterns (except LF-HRV) between PAN and HC at rest. Under stress, PAN (vs. HC) demonstrated a blunted HR [condition*time*group: F(2.91, 104.98) = 9.326, p = 0.000, η2 = 0.206] and an attenuated HRV response (reduced SNS/PNS reactivity). Significant effects of stress appraisal (SA) and BMI on HRV-reactivity were revealed. SA on SDNN = Condition*time*SA = F(4.12, 140.15) = 2.676, p = 0.033, η2 = 0.073. BMI on LF/HF-Ratio = Condition*time*BMI = F(3.53, 60.16) = 3.339, p = 0.019, η2 = 0.164. Psychological indices suggested higher levels of chronic and appraised stress in PAN relative to HC. Additional analyses demonstrated that ED-symptoms are highly correlated with the latter constructs, as well as with psychological burden, but not with weight. Further, it was shown that abnormalities in reactivity persisted despite normalized ANS activity. Overall, we suggested that besides weight recovery, improvement in stress appraisal could be beneficial for cardiac health. In this light, a combination of therapy (e.g., development and activation of coping skills, cognitive reappraisal) and biofeedback training may improve treatment outcomes and regulate stress reactivity.


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