scholarly journals Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice

F1000Research ◽  
2013 ◽  
Vol 2 ◽  
pp. 177 ◽  
Author(s):  
Tanya Myers-Morales ◽  
Kate M Bussell ◽  
Sarah EF D'Orazio

The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses.  In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota.  Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection.   Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice.  Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.

2015 ◽  
Vol 9 (2) ◽  
pp. 187-198 ◽  
Author(s):  
Kathryn Milligan-Myhre ◽  
Clayton M. Small ◽  
Erika K. Mittge ◽  
Meghna Agarwal ◽  
Mark Currey ◽  
...  

Author(s):  
Indranil Chattopadhyay ◽  
Esaki M. Shankar

Gut microbiome alterations may play a paramount role in determining the clinical outcome of clinical COVID-19 with underlying comorbid conditions like T2D, cardiovascular disorders, obesity, etc. Research is warranted to manipulate the profile of gut microbiota in COVID-19 by employing combinatorial approaches such as the use of prebiotics, probiotics and symbiotics. Prediction of gut microbiome alterations in SARS-CoV-2 infection may likely permit the development of effective therapeutic strategies. Novel and targeted interventions by manipulating gut microbiota indeed represent a promising therapeutic approach against COVID-19 immunopathogenesis and associated co-morbidities. The impact of SARS-CoV-2 on host innate immune responses associated with gut microbiome profiling is likely to contribute to the development of key strategies for application and has seldom been attempted, especially in the context of symptomatic as well as asymptomatic COVID-19 disease.


Aquaculture ◽  
2018 ◽  
Vol 491 ◽  
pp. 239-251 ◽  
Author(s):  
Mayra L. González-Félix ◽  
Delbert M. Gatlin ◽  
Perla Urquidez-Bejarano ◽  
Carolina de la Reé-Rodríguez ◽  
Lyra Duarte-Rodríguez ◽  
...  

2012 ◽  
Vol 95 (1) ◽  
pp. 35-49 ◽  
Author(s):  
Julia M Green-Johnson

Abstract The integral nature of interactions between the gut microbiota and host is especially evident with respect to effects on the immune system and host defenses. Host-microbiota interactions are increasingly being revealed as complex and dynamic, with far-reaching effects on varied aspects of host health. This review focuses on adaptive and innate immune responses to the gut microbiota and the bidirectional nature of these host-microbe interactions.


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