scholarly journals Comparison of effects of medicinal cannabis or standard palliative care on quality of life of patients with cholangiocarcinoma in Northeast Thailand

F1000Research ◽  
2022 ◽  
Vol 11 ◽  
pp. 20
Author(s):  
Narisara Phansila ◽  
Chaiyasit Sittiwet ◽  
Ranee Wongkongdech
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
Rank Test ◽  
Northeast Thailand ◽  
Care Clinic ◽  
Early Access ◽  
Signed Rank Test ◽  
Medicinal Cannabis ◽  
Pre Treatment

Background: Cholangiocarcinoma (CCA) has a poor prognosis and is a major cause of mortality and suffering in Thailand’s Northeastern (Isaan) Region.   Methods: This prospective cohort study aimed to compare the health-related quality of life (HRQoL) among 72 newly diagnosed CCA patients; 42 patients who received cannabis treatment (CT) and 30 patients who received a standard palliative care treatment (ST). The study was carried out between 1st September 2019 to 31st October 2020.  Data were collected from patients from oncology clinics of six hospitals in five provinces of northeast Thailand. The HRQoL was measured at baseline, and at 2 and 4 months after diagnosis by the European Organisation for Research and Treatment of Cancer (EORTC) Core Quality of Life questionnaires QLQ-C30, and QLQ-BIL21. The Mann-Whitney U-test was performed to compare quality of life scores between the two patient groups and Wilcoxon signed rank test was performed to compare within groups QoL scores at pre-treatment, and 2 and 4 month follow-ups. Results: Global health status and functional scales, for both groups were high at pre-treatment. At 2 and 4 month follow-up, CT group patients had consistent statistically significantly better Palliative Performance Scale (PPS), and QoL scores, and many symptom scores than the ST group.   Conclusions: Medicinal cannabis may increase QoL for advanced CCA patients. Our findings support the importance of early access to palliative cannabis care clinic before the terminal and acceleration phase close to death.

scholarly journals A Large Randomized Trial: Effects of Mindfulness-Based Stress Reduction (MBSR) for Breast Cancer (BC) Survivors on Salivary Cortisol and IL-6

2018 ◽  
Vol 21 (1) ◽  
pp. 39-49 ◽  
Author(s):  
Cecile A. Lengacher ◽  
Richard R. Reich ◽  
Carly L. Paterson ◽  
Melissa Shelton ◽  
Steve Shivers ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Stress Reduction ◽  
Salivary Cortisol ◽  
Rank Test ◽  
Signed Rank ◽  
Wilcoxon Signed Rank Test ◽  
Signed Rank Test ◽  
Mindfulness Based Stress Reduction

Breast cancer survivors (BCS) often experience psychological and physiological symptoms after cancer treatment. Mindfulness-based stress reduction (MBSR), a complementary and alternative therapy, has reduced subjective measures of stress, anxiety, and fatigue among BCS. Little is known, however, about how MBSR affects objective markers of stress, specifically the stress hormone cortisol and the pro-inflammatory cytokine interleukin-6 (IL-6). In the present study, BCS ( N = 322) were randomly assigned to a 6-week MBSR program for BC or usual-care control. Measurements of cortisol, IL-6, symptoms, and quality of life were obtained at orientation and 6 weeks. Cortisol and IL-6 were also measured prior to and after the MBSR(BC) class Weeks 1 and 6. The mean age of participants was 56.6 years and 69.4% were White non-Hispanic. Most had Stage I (33.8%) or II (35.7%) BC, and 35.7% had received chemotherapy and radiation. Cortisol levels were reduced immediately following MBSR(BC) class compared to before the class Weeks 1 and 6 (Wilcoxon-signed rank test; p < .01, d = .52–.56). IL-6 was significantly reduced from pre- to postclass at Week 6 (Wilcoxon-signed rank test; p < .01, d = .21). No differences were observed between the MBSR(BC) and control groups from baseline to Week 6 using linear mixed models. Significant relationships with small effect sizes were observed between IL-6 and both symptoms and quality of life in both groups. Results support the use of MBSR(BC) to reduce salivary cortisol and IL-6 levels in the short term in BCS.

scholarly journals Implant-Supported Removable Partial Denture Improves the Quality of Life of Patients with Extreme Tooth Loss

2015 ◽  
Vol 26 (5) ◽  
pp. 463-467 ◽  
Author(s):  
Camila Heitor Campos ◽  
Thais Marques Simek Vega Gonçalves ◽  
Renata Cunha Matheus Rodrigues Garcia
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Tooth Loss ◽  
Health Impact ◽  
Rank Test ◽  
Removable Partial Denture ◽  
Osseointegrated Implants ◽  
Related Quality ◽  
Signed Rank Test

Abstract: This study aimed to evaluate oral health-related quality of life (OHRQoL) in partially dentate subjects, presenting extreme tooth loss in posterior region with missing post-canines, comparing the use of conventional removable partial dentures (RPDs) and implant-supported RPDs. OHRQoL was measured using the Brazilian version of the Oral Health Impact Profile. Twelve subjects presenting maxillary total and mandibular Kennedy Class I edentulism (mean age 62.6±7.8 years) first received complete maxillary dentures and conventional mandibular free-end RPDs. After two months, the subjects had their OHRQoL assessed. Osseointegrated implants were inserted bilaterally in the mandibular first molar regions, and after four months ball abutments were placed to support the free-end RPD. Two months later, the patients had their OHRQoL reassessed. Wilcoxon signed-rank test was used to evaluate differences in OHRQoL (α=0.05). Results showed improvement in all OHIP-49 domains (p<0.05) after associating implants to the RPD. The mandibular implant-supported free-end RPD significantly improved OHRQoL.

scholarly journals Peningkatan Kualitas Hidup Penderita Kusta Dengan Menggunakan Metode Self Help Group (SHG)

2017 ◽  
Vol 6 (1) ◽  
pp. 82
Author(s):  
Ifa Roifah
Keyword(s):  
Quality Of Life ◽  
Complex Problem ◽  
Poor Quality ◽  
Point Of View ◽  
Rank Test ◽  
P Value ◽  
Self Help ◽  
Signed Rank Test ◽  
Self Help Group

Leprosy is one of the infectious diseases that cause a very complex problem, not only from a medical point of view. In addition there is a negative stigma from the community tends to cause the quality of life of people with leprosy decline. Quality of life is the concept of individual ability analysis to get a normal life associated with individual perceptions of goals and expectations, one of the measures to improve the quality of life of leprosy is by doing Self Help Group (SHG) therapy. This study aims to determine the quality of life in people with leprosy. The design of this research using pra experiment with pretest-posttest design approach. The samples were taken with the techniques of cluster random sampling as much as 15 respondents. Tool used WHOQOL-BREF questionnaire containing 26 questions. Patients with leprosy prior to being given Self Help Group (SHG) from 15 respondents mostly experience poor quality of life 7 people (46,7%), leprosy patient after given Self Help Group (SHG) that from 15 respondents mostly experience quality of life is 5 people (33.3%). The test used is using Wilcoxon Signed Rank Test. p value = 0,007 and α = 0,05 so Ha is accepted, it  means there is influence Self Help Group therapy (SHG) to quality of life in leprosy patients in tanjungkenongo village sumberglagah kec. Pacet kab. Mojokerto. Self Help Group (SHG) is a group or peer where each member share the same physical or emotional issues or specific issues where they work together to share problems and choose what will be the focus of solving group members, helping each other in motivating to create a sense of prosperity.

scholarly journals Pengaruh Program Empathic Caring Consultation terhadap Professional Quality of Life Pada Psikolog

2020 ◽  
Vol 12 (2) ◽  
pp. 97-106
Author(s):  
Anya Asbar ◽  
Maya Khairani ◽  
Marty Mawarpury
Keyword(s):  
Quality Of Life ◽  
Sampling Method ◽  
Rank Test ◽  
Professional Quality Of Life ◽  
Professional Quality ◽  
Signed Rank ◽  
Before And After ◽  
Post Test ◽  
Signed Rank Test

This study aims to determine the effect of the Empathic Caring Consultation (ECC) program on Professional Quality of Life (ProQOL) in psychologists. This study involved seven psychologists. The research sample was taken using purposive sampling method. The research method used was one group pretest-post test design. ProQOL is measured using the Professional Quality of Life Version V scale, while the implementation of ECC training refers to the concept of Prawitasari. Analysis using Wilcoxon signed-rank test with a significant value (p) = 0.340 (BO); 0.932 (STS); 0.496 (CS) (p> 0.05). The results of the study showed that there was no effect of the ECC program on ProQOL on psychologists. This is because there are several variations of the three ProQOL components before and after treatment.

scholarly journals Quality of Life of Diabetic Foot Ulcer Patients with Hyperbaric Oxygen Therapy

2019 ◽  
Vol 55 (2) ◽  
pp. 127
Author(s):  
Kusnanto Kusnanto ◽  
Dismalyansa Dismalyansa ◽  
Retnayu Pradanie ◽  
Hidayat Arifin
Keyword(s):  
Quality Of Life ◽  
Hyperbaric Oxygen ◽  
Diabetic Foot ◽  
Intervention Group ◽  
Foot Ulcer ◽  
Foot Ulcers ◽  
Rank Test ◽  
Control Group ◽  
Signed Rank Test

DM with ulcer can result in a decrease in the quality of life of patients and need to reduce the intensity of pain and odor on the ulcer, preventing amputation and Hyperbaric Oxygen as an adjuvant therapy in accelerating wound healing. This study aims to explain the effect of HBO on the quality of life of patients with diabetic foot ulcers at RSAL Dr. Ramelan Surabaya. Methods: The research used quasi-experimental design with a non-equivalent control group design approach. The samples were 70 patients from population of all diabetes patients who suffered from diabetic foot ulcers at RSAL Dr. Ramelan. Data were collected by WHOQOL-BREF questionnaire. Analyzed byWilcoxon signed rank test and Mann Whitney U test. Result: Mann Whitney in the post test, the physical p-value domain (0.000), psychological domain (0.012), social domain (0.003), and environmental domain (0,001), where the intervention group has a better value than the control group. Wilcoxon signed rank test results on the physical domain (0,000), psychological (0,012), social (0,003), and environmental (0,001), meaning there were significant differences between pre post test in intervention group. Discussion: Diabetes mellitus patients with foot ulcers given hyperbaric oxygen showed improvement on wound condition, thus reducing pain and medical needs. This makes patients motivated, reduce anxiety, and improve interpersonal support and confidence. Therefore, it is necessary to socialize the effect of HBO on DM patients with foot ulcer, as a treatment option in improving the quality of life of DM patients with foot ulcers.

scholarly journals Parent-assessed quality of life among adolescents undergoing orthodontic treatment: a 12-month follow-up

2015 ◽  
Vol 20 (5) ◽  
pp. 94-100 ◽  
Author(s):  
Lucas Guimarães Abreu ◽  
Camilo Aquino Melgaço ◽  
Mauro Henrique Nogueira Guimaraes Abreu ◽  
Elizabeth Maria Bastos Lages ◽  
Saul Martins Paiva
Keyword(s):  
Quality Of Life ◽  
Orthodontic Treatment ◽  
Well Being ◽  
Rank Test ◽  
Brazilian Version ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Fixed Appliances ◽  
Parents And Caregivers

Objective: To assess parents' and caregivers' view of the first twelve months of adolescents' orthodontic treatment with fixed appliances and to assess the evaluative properties of the Brazilian version of the Parental-Caregiver Perceptions Questionnaire (P-CPQ) in the orthodontic setting.Methods:Data from a sample of 96 parents and caregivers of adolescents undergoing orthodontic treatment with fixed appliances were collected by means of P-CPQ. Assessments were performed before banding and bracket bonding (T1) and 12 months after placement of fixed appliances (T2). Statistical analysis included Wilcoxon signed-rank test for the overall P-CPQ score and Bonferroni correction for P-CPQ subscales. The evaluative properties of the P-CPQ were assessed through responsiveness calculation and the minimally clinical important difference (MCID).Results: Among the 96 participants, 76 were mothers of patients, 16 were fathers, and four were other family members. Adolescents' mean age was 11.49 ± 0.50 years. Most families earned equal to or less than three times the Brazilian monthly minimum wage. There was significant improvement in the emotional and social well-being subscales (p< 0.001), which contributed to improve patient's overall quality of life (p< 0.001). Reductions in scores were associated with clinically meaningful moderate changes in the overall score as well as in the emotional and social well-being subscales. The MCID was 6.16 for the P-CPQ overall score.Conclusion:Parents and caregivers reported significant improvement in the quality of life of adolescents undergoing orthodontic treatment with fixed appliances.

Quality of life from the perspective of the palliative care patient in a resource-poor community in South Africa

2012 ◽  
Vol 11 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Jacoba J.M. Jansen van Rensburg ◽  
Johanna E. Maree ◽  
Corrien van Belkum
Keyword(s):  
Quality Of Life ◽  
South Africa ◽  
Palliative Care ◽  
Phenomenological Study ◽  
Symptom Control ◽  
Negative Influence ◽  
Self Report ◽  
Care Clinic ◽  
Resource Poor

AbstractObjective:Quality of life is an ill-defined term, as it means different things to different people. Quality of life has been well researched, especially with respect to people with cancer, but not necessarily from the perspective of the patient, and also, not in Third World, resource-poor countries. The objective of this study was to explore quality of life from the perspective of palliative care patients managed at a palliative care clinic serving a resource-poor community in Tshwane, South Africa.Method:An exploratory, qualitative phenomenological study was conducted. The target population for this study was all patients managed at a palliative care clinic serving a resource-poor community in Tshwane. Self-report data were gathered by means of in-depth interviews. The data were analyzed using a template analysis style as well as content analysis using open coding. Data analysis was done concurrently with data gathering. Data saturation was reached after 10 interviews (n = 10).Results:Three themes arose from the data: factors that had a positive influence on quality of life, factors that had a negative influence on quality of life, and experience of quality of life. Work played the most important role in quality of life whereas only one participant linked symptom control with quality of life. Experiencing symptoms, rejection, and stigmatization had a negative influence on quality of life. Friends and religion played a significant role and added to quality of life.Significance of results:Life was a daily struggle for survival. Poverty was so overwhelming that quality of life was primarily measured in terms of the ability to buy food and other basic commodities.

PP043-SUN THE NUTRITIONAL STATUS AND QUALITY OF LIFE IN PATIENTS OF A PALLIATIVE CARE CLINIC

2011 ◽  
Vol 6 (1) ◽  
pp. 39
Author(s):  
A. Ticha ◽  
R. Hyspler ◽  
M. Simkova ◽  
S. Filip ◽  
L. Slovacek ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
Nutritional Status ◽  
Care Clinic

scholarly journals A retrospective analysis with quality of life assessment of nasal surgery for nasal obstruction

2018 ◽  
Vol 5 (1) ◽  
pp. 5
Author(s):  
Mehmet Fatih Karakus ◽  
Suleyman Emre Karakurt ◽  
Mustafa Colak
Keyword(s):  
Quality Of Life ◽  
Nasal Obstruction ◽  
Life Assessment ◽  
Rank Test ◽  
Signed Rank ◽  
Symptom Evaluation ◽  
Signed Rank Test ◽  
The Difference ◽  
Age Range

<p class="abstract"><strong>Background:</strong> Nasal obstruction is a common health problem that disrupts a person’s quality of life (QoL). The Nasal Obstruction Symptom Evaluation scale (NOSE) is a QoL scale with questions specific to nasal obstruction symptoms. This study aimed to evaluate surgical success in patients who underwent nasal septal deviation surgery by using a NOSE assessment, thus determining the importance and efficacy of surgery in this group of patients.</p><p class="abstract"><strong>Methods:</strong> This study was conducted in between January 2016 and June 2017, including a total of 60 patients. The age range of the patients was 18–57 (mean, 34.4±9.9 years). The preoperative and postoperative scoring and surgeries were performed by the same investigator. The surgeries were septoplasty and radiofrequency applied to the inferior concha to overcome conchal hypertrophy. Preoperative mean scores were compared with postoperative second-month values. The importance of difference was evaluated with the Wilcoxon signed-rank test.  </p><p class="abstract"><strong>Results:</strong> Preoperative minimum, maximum and mean scores were 65.0, 100.0 and 83.4 (83.41±8.15), respectively. Postoperative minimum, maximum and mean scores were 10.0, 35.0 and 21.6 (21.66±8.06), respectively. The difference in mean scores was significant (Z=−6.778; p&lt;0.001).</p><p class="abstract"><strong>Conclusions:</strong> The difficulty in evaluating patient satisfaction and postoperative success stems from differences in each surgeon’s approach and the comparison of preoperative and postoperative findings. This study, which was carried out by the same researcher for all steps, differs it from similar studies.</p>

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