scholarly journals Improving in the Fasting, but Not the Postprandial, Glucose Level is Associated with Reduction of Plasma d-ROMs Level in Patients with Type 2 Diabetes

2013 ◽  
Vol 80 (3) ◽  
pp. 200-210 ◽  
Author(s):  
Makoto Ohara ◽  
Kentaro Watanabe ◽  
Tatsuya Suzuki ◽  
Ken-ichi Sekimizu ◽  
Masayuki Motoyama ◽  
...  
2020 ◽  
Vol 9 (3) ◽  
pp. 811
Author(s):  
Ni Wayan Trisnadewi ◽  
I Made Sudarma Adiputra ◽  
Ni Putu Wiwik Oktaviani ◽  
Putu Aris Suapriyanti ◽  
Ni Luh Gede Intan Saraswati

2017 ◽  
Vol 52 (2) ◽  
pp. 127
Author(s):  
Laili Zahrina Marchelia ◽  
Purwati Purwati ◽  
Rio Wironegoro

Type 2 diabetes mellitus (DM) is the 10th leading cause of death in the world and had a risk 4.06 times greater to have cardiovascular disease (CVD). Fasting plasma glucose and 2-hours postprandial glucose level as diagnostic tests to evaluate DM and also as a predictive factors to CVD. This research uses descriptive analytic research with cross sectional design. The subject of this study is Type 2 DM patients came to Dr Soetomo hospital from January-October 2014. Data was recorded from medical records of patients and was analyzed with Chi Square test with p<0.05. As result, there is 102 Type 2 DM patients with 36 patients have CVD manifestation and 66 patients without complication. There is a significant association between fasting plasma glucose (FPG), 2-hours postprandial glucose (2hPPG) level, and CVD manifestation (p=0.00). So FPG and 2hPPG have a significant association with CVD manifestation. There are other factors that influencing the formation of CVD, hence, further research is needed.


10.3823/2540 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Deici Aparecida Gomes Rodrigues ◽  
Isabela Macêdo Alves ◽  
Isabelly De Oliveira Pinheiro ◽  
Élida Camilla Nunes Valões ◽  
Erich Pires Lisboa

The SGLT2 inhibitors are a class of drugs that blocks the sodium-glucose co-transport, which is responsible for 90% of the nephron glucose. Objective: To show the benefits of the SGLT2 inhibitors in monotherapy and in association with other drugs. Results: The association of SGLT2 inhibitors and other drugs has shown several additional benefits after their interaction, including weight loss, reduction of body fat, reduction of triglycerides level, decrease of glycated hemoglobin, decrease in postprandial glucose level, reduction of arterial pressure, decrease of hypoglycemia risk and improvement of glucose metabolism. Therefore, this is a promising interaction for type 2 diabetes.


Author(s):  
Lakshmi E

 Objective: The objective of this study was to optimize recipes incorporating Indian blackberry (Syzygium cumini) seed flour (SCSF) in biscuits for its organoleptic feel and assess its impact on the anthropometric status of Type 2 diabetes mellitus.Method: The study was designed to include 20 Type 2 and 20 normoglycemic controls. Biscuits were prepared using four blends (10 g, 15 g, 20 g, and 25 g) of SCSF with a control. The diabetic subjects were supplemented with Indian blackberry SCSF (20 g) biscuits. Nutritional status was assessed such as body mass index (BMI) and waist-hip ratio (WHR). Results were analyzed statistically by two-way ANOVA and paired t-test.Results: Statistically, there was a significant difference (p<0.001) in flavor and taste perception between diabetics and normoglycemic. The mean fasting and postprandial glucose level decreased much (p<0.001). There was a significant (p<0.001) decrease in the BMI and WHR


2008 ◽  
Vol 46 (09) ◽  
Author(s):  
J Wörle ◽  
T Lindenberger ◽  
M Albrecht ◽  
R Linke ◽  
JE Foley ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Xiang Li ◽  
Hui Ren ◽  
Zhang-rong Xu ◽  
Yan-jun Liu ◽  
Xiao-pin Yang ◽  
...  

Objectives. The aim of this study was to evaluate the prevalence and the risk factors of prolonged QTc interval among Chinese patients with type 2 diabetes.Methods. The retrospective study included 3156 outpatients from the Diabetes Centre, the 306th Hospital of PLA, during the period from September 2003 to June 2010. QT interval was measured manually in the 12-lead conventional electrocardiogram. The QT interval corrected for heart rate (QTc) was calculated using Bazett’s formula. Additional demographic and laboratory data were also collected. Potential risk factors of prolonged QTc interval were assessed using multivariable regression.Results.The prevalence of prolonged QTc interval among Chinese patients with type 2 diabetes was 30.1%. Height (OR 0.156, 95% CI 0.032~0.748), waist circumference (OR 1.025, 95% CI 1.010~1.040), diastolic blood pressure (OR 1.016, 95% CI 1.007~1.026), postprandial glucose (OR 1.040, 95% CI 1.022~1.059), fasting insulin (OR 1.014, 95% CI 1.003~1.025), and presence of microalbuminuria (OR 1.266, 95% CI 1.033~1.551) were significant risk factors.Conclusions. The prevalence of prolonged QTc interval among Chinese patients with type 2 diabetes is high. Risk factors for prolongation of QTc interval were low height, high waist circumference, increasing diastolic blood pressure levels, high postprandial glucose levels, high fasting insulin levels, and presence of microalbuminuria.


2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Jing Ma ◽  
Huan Zhou ◽  
Hua Xu ◽  
Xie Chen ◽  
Xiangyu Teng ◽  
...  

Background. It has been well accepted that insulin therapy is the ideal treatment for newly diagnosed diabetic patients. However, there was no study about assessment of the initial insulin dosage in new onset Chinese patients with type 2 diabetes.Research Design and Methods. 65 newly diagnosed patients with type 2 diabetes (39 males/26 females; HbA1c ≥ 11.80 ± 0.22%) were investigated. All patients had random hyperglycaemia (at 21.8 ± 3.9 mmol/L) on the first day of admission and received insulin infusion intravenously (5 U/per hour). When the blood glucose level dropped to around 10 mmol/L, patients were then transferred to continuous subcutaneous insulin infusion (CSII). The reduction of blood glucose levels in response to per unit of insulin (RBG/RI) was recorded. The target glucose level was achieved in about 3 days. The total daily insulin dose (TDD) and basal insulin dose (TBD) were calculated.Results. TDD was 45.97 ± 1.28 units and TBD was 19.00 ± 0.54 units. TBD was about 40% of the total daily insulin requirement. There was a negative correlation between the ratio of RBG/RI and TDD.Conclusions. TDD was correlated with blood glucose reduction in response to intravenous insulin infusion in Chinese new onset patients with type 2 diabetes.


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