Place of magnesium deficiency in cardiovascular continuum: pathophysiology, symptoms and treatment

The article presents modern concepts of “cardiovascular continuum”, where there are stages of heart disease risk factors up to death. The fundamental constant is a magnesium deficiency as a risk factor for endothelial dysfunction. The authors show the way of absorption, distribution of the elimination of magnesium, the regulatory significance of genes, providing its bioavailability. Symptoms of magnesium deficiency on the part of the cardiovascular system are characterized. The authors specify the involvement of magnesium in the develop-ment of metabiological syndrome, the possibilities of correction of its content, respectively, and insulin resis-tance. An anti-arrhythmogenic effect of the drug magnesium – Magnerot - was proven.