scholarly journals OnThe Essence Of Shareholder’s Right

2015 ◽  
Vol 3 (6) ◽  
pp. 307-314
Author(s):  
Лоу Куйран ◽  
Lou Qiuran
Keyword(s):  
Stable Structure ◽  
Probable Nature

The shareholder’s right has been regarded as a special right, which is substantially different from creditor’s right, in China. However, with the development of business reality, the boundaries between these two rights have been blurred already. Although the structure of shareholder’s right has a probable nature, compared to a more stable structure of credit, there are lots of overlaps between these two structures. Thus, an additional standard, whether investor is registered as shareholder, is required to completely distinguish these two rights.

Random Forest Refinement of Pairwise Potentials for Protein-ligand Decoy Detection

2019 ◽  
Author(s):  
Jun Pei ◽  
Zheng Zheng ◽  
Hyunji Kim ◽  
Lin Song ◽  
Sarah Walworth ◽  
...  
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Probability Function ◽  
Pair Potential ◽  
Scoring Function ◽  
Stable Structure ◽  
Scoring Functions ◽  
Atom Pair ◽  
Data Set ◽  
Atom Pairs

An accurate scoring function is expected to correctly select the most stable structure from a set of pose candidates. One can hypothesize that a scoring function’s ability to identify the most stable structure might be improved by emphasizing the most relevant atom pairwise interactions. However, it is hard to evaluate the relevant importance for each atom pair using traditional means. With the introduction of machine learning methods, it has become possible to determine the relative importance for each atom pair present in a scoring function. In this work, we use the Random Forest (RF) method to refine a pair potential developed by our laboratory (GARF6) by identifying relevant atom pairs that optimize the performance of the potential on our given task. Our goal is to construct a machine learning (ML) model that can accurately differentiate the native ligand binding pose from candidate poses using a potential refined by RF optimization. We successfully constructed RF models on an unbalanced data set with the ‘comparison’ concept and, the resultant RF models were tested on CASF-2013.5 In a comparison of the performance of our RF models against 29 scoring functions, we found our models outperformed the other scoring functions in predicting the native pose. In addition, we used two artificial designed potential models to address the importance of the GARF potential in the RF models: (1) a scrambled probability function set, which was obtained by mixing up atom pairs and probability functions in GARF, and (2) a uniform probability function set, which share the same peak positions with GARF but have fixed peak heights. The results of accuracy comparison from RF models based on the scrambled, uniform, and original GARF potential clearly showed that the peak positions in the GARF potential are important while the well depths are not. <br>

scholarly journals “Probable Nature of the Internal Symmetry of Crystals”

Nature ◽  
1884 ◽  
Vol 29 (747) ◽  
pp. 383-384 ◽  
Author(s):  
L. SOHNCKE
Keyword(s):  
Internal Symmetry ◽  
Probable Nature

Stable structure and optical properties of fused silica with NBOHC- E ′ defect

2016 ◽  
Vol 25 (8) ◽  
pp. 086801 ◽  
Author(s):  
Peng-Fei Lu ◽  
Li-Yuan Wu ◽  
Yang Yang ◽  
Wei-Zheng Wang ◽  
Chun-Fang Zhang ◽  
...  
Keyword(s):  
Optical Properties ◽  
Fused Silica ◽  
Stable Structure

scholarly journals THE PROBABLE NATURE OF THE INFECTIOUS AGENT OF TRACHOMA

1937 ◽  
Vol 65 (5) ◽  
pp. 735-755 ◽  
Author(s):  
L. A. Julianelle ◽  
R. W. Harrison ◽  
M. C. Morris
Keyword(s):  
Tissue Culture ◽  
Gentian Violet ◽  
Infectious Agent ◽  
Heat Inactivation ◽  
Time Interval ◽  
General Observation ◽  
Specific Reaction ◽  
Rare Occasion ◽  
Probable Nature ◽  
The Brain

1. The infectious agent of trachoma can be freed from extraneous bacteria by passage through rabbit testicle. 2. The infectious agent multiplies little, if at all, during such passage, but in many instances retains its infectivity undiminished. 3. No specific changes occur in the rabbit testicle incidentally to the passage. 4. On rare occasion the trachoma agent may be freed from bacteria by intracerebral passage. The brain tissues show no specific reaction. 5. Filtration experiments with Seitz, Kramer, Berkefeld, and Elford filters confirm the general observation that the infectious agent is filterable with difficulty. 6. Tissue culture experiments, with tissues containing the infectious agent (conjunctiva, rabbit testicle, brain, etc.), conducted under a wide variety of conditions, proved uniformly unsuccessful in the cultivation of the agent. 7. The agent is inactivated by bile, AgNO3, phenol, cocaine, tartar emetic, and gentian violet. Its heat inactivation temperature is between 45° and 50°C., at a time interval of 15 minutes. 8. Attempts to preserve the infectious agent in glycerine were unsuccessful. 9. The accumulated evidence suggests that the infectious agent of trachoma is a virus.

scholarly journals Conjugated organic framework with three-dimensionally ordered stable structure and delocalized π clouds

2013 ◽  
Vol 4 (1) ◽  
Author(s):  
Jia Guo ◽  
Yanhong Xu ◽  
Shangbin Jin ◽  
Long Chen ◽  
Toshihiko Kaji ◽  
...  
Keyword(s):  
Stable Structure ◽  
Organic Framework

Memoirs: The Cytopasmic Inclusion of the Germ-Cells

1917 ◽  
Vol s2-62 (247) ◽  
pp. 407-463
Author(s):  
J. BRONTÉ GATENBY
Keyword(s):  
Germ Cell ◽  
Primordial Germ Cell ◽  
Growth Period ◽  
Pieris Brassicae ◽  
Constant Factor ◽  
Cytoplasmic Bodies ◽  
Female Germ Cell ◽  
Probable Nature ◽  
And Function ◽  
Definite Period

(1) In Smerinthus populi, Pieris brassicæ, and a number of other species of moths and butterflies the cytoplasmic bodies have been followed out. (2) The micromitosome lias been followed from the spermatocyte back into the secondary spermatogonium. It is very probably present in the primordial germ-cell. (3) The micromitosome has been definitely found in the female. (4) The micromitosome seems to divide in all divisions, and I consider that it is a constant factor in the spermatids of Smerinthus. (5) The probable nature and function of the micromitosome is discussed. (6) The mitochondria have been carefully examined in the male and female germ-cell in all stages except in the maturation division of the female and in fertilisation. (7) It has been shown that in early stages the cytoplasmic bodies of the female resemble those of the male. (8) There is a definite period, judged to be about the beginning of growth stage, when the subsequent fate of the mitochondria in the male becomes different from that of the female. (9) The remarkable formation of chromophobe and chromophile zones in the male mitochondrial body aud the use of these zones are described. (10) The formation of the macromitosome from the mitochondria is described. (11) The changes undergone by the macromitosome in sperm formation are followed out. (12) The presence of the acroblasts in the fairly early growth period of the spermatocyte is described. (13) The complicated evolutions of these bodies in division of the cells, their subsequent fate and' their probable nature are discussed. (14) The staining and fixing reactions of the cytoplasmic bodies are fully described. (15) A number of abnormalities have been described. (16) The centrosome has been shown to divide in the young spermatid, and one centrosome is probably lost, but definite evidence is not forthcoming.

On the Impact Behavior of a Material With a Yield Point

1949 ◽  
Vol 16 (1) ◽  
pp. 39-52
Author(s):  
Merit P. White
Keyword(s):  
Yield Stress ◽  
Yield Point ◽  
Impact Behavior ◽  
Longitudinal Impact ◽  
Stress Strain ◽  
California Institute Of Technology ◽  
Static Yield ◽  
Institute Of Technology ◽  
Probable Nature ◽  
The Impact

Abstract An analysis of longitudinal impact tests that were made by Drs. D. S. Clark and P. E. Duwez at the California Institute of Technology on an iron and a steel with definite yield points is described. From this analysis is deduced the probable nature of the dynamic stress-strain relations for such materials. These appear to differ greatly from the static stress-strain relations, unlike the case for materials without yield points. As pointed out by Duwez and Clark, the upper yield stress for undeformed material is several times as great under impact as the static yield stress. The present analysis indicates that under impact, the material with a definite yield point is made harder at a given deformation, and ruptures at a higher (engineering) stress and smaller strain than when loaded statically. The critical impact velocity, defined as that at which nearly instantaneous failure occurs in tension, is discussed, and the factors upon which it depends are given.

scholarly journals Probable Nature of the Internal Symmetry of Crystals 1

Nature ◽  
1883 ◽  
Vol 29 (739) ◽  
pp. 205-207 ◽  
Author(s):  
WILLIAM BARLOW
Keyword(s):  
Internal Symmetry ◽  
Probable Nature

scholarly journals A Rationale for Using Sonoelastography in Thyroid Nodular Pathology

2019 ◽  
Vol 100 (5) ◽  
pp. 242-246
Author(s):  
L. A. Timofeeva ◽  
L. B. Shubin
Keyword(s):  
Thyroid Cancer ◽  
Roc Analysis ◽  
Thyroid Nodules ◽  
Area Under The Curve ◽  
Predictive Ability ◽  
Tissue Elasticity ◽  
Stromal Component ◽  
Collagen Level ◽  
Probable Nature ◽  
Benign Nodules

Objective. To provide a rationale for using sonoelastography (SEG) in the differential diagnosis of thyroid cancer (TC).Material and methods. Thirty patients with thyroid nodules of various morphological structures were examined. The authors studied the data of SEG and immunohistochemistry (IHC) with monoclonal antibodies against types III and IV collagen (they evaluated the degree of the expressed collagen fibers). Analysis of variance, ROC analysis, and logistic regression were used (by comparing with the expression of collagens) to assess the predictive ability of ultrasound.Results. The study showed that irregular and uneven contours, microcalcifications, and “the height greater than the width” were most significant among the ultrasound signs in the diagnosis of TC. Cool colors prevailed when performing SEG in the pattern of thyroid cancer. Purple-blue hues were predominantly recorded (p<0.05 with regard to benign nodules), green ones were less frequently. ROC analysis of compression elastography showed that the area under the curve was 0.785 (95% CI 0.740-0.826), sensitivity 78.1%, specificity 79.0%. Comparison of the data of IHC and SEG revealed a direct correlation of tissue elasticity with the degree of a stromal component and with the presence of collagen-containing structures.Conclusion. SEG may suppose the probable nature of thyroid nodules on the basis of their morphological features. The low degree of the stromal component and the low content of types III and IV collagen make follicular colloid goiter and adenoma soft, which is recorded at SEG. TC is characterized by a high collagen level attributable to the characteristics of the metabolism of cancer cells, which makes them solid in the mode of SEG.

Sign in / Sign up

Export Citation Format

Share Document