scholarly journals Cognitive symptoms associated with antipsychotic course experience in residual schizophrenia

2021 ◽  
Vol 11 (6) ◽  
pp. 277-283
Author(s):  
D. Safonov
Keyword(s):  
Verbal Memory ◽  
Verbal Fluency ◽  
Negative Impact ◽  
Motor Task ◽  
Memory Test ◽  
Tower Of London ◽  
Verbal Fluency Test ◽  
Course Experience ◽  
Test Result ◽  
Fluency Test

Urgency. The cognitive symptoms of schizophrenia are recognized either as a part of a negative complex of symptomatic, where cognitive malfunction seem to be the secondary complication of emotional and motivational dysregulation; or as a separate group of schizophrenia manifestations that constitutes a massive part of a residual condition. Aim – to evaluate the cognitive functioning and analyze its violation levels in association with antipsychotic course experience in patients with residual schizophrenia. Results. The assessment of cognitive functions was established by direct testing in clinical setting. Education in years varied from 9 to 16, mean 11,27±2,12 in the population under study. The basic level of cognitive impairment was established: verbal memory test result was 31,6±11,6; digit sequencing test result was 13,4±5,7; token motor task test result was 40,1±18,3; verbal fluency test result was 41,2±10,7; symbol coding test result was 30,6±13,1; tower of london test result was 12,2±4,5. Some correlations were found: for chlorpromazine we can assume minor negative impact on token motor task (r= -0,22) and verbal fluency test (r= -0,27) results; for haloperidol we can assume more pronounced but still minor impact on token motor task (r= -0,22), verbal fluency test (r= -0,27), verbal memory test (r= -0,28) and tower of London test (r= -0,20) results; for trifluoperazine we can see minor negative impact on  verbal fluency test (r= -0,26); for clozapine we can’t find any representative correlations with cognitive tests; chlorprothixene as we can assume have minor negative impact on verbal memory test (r= -0,32) result, but minor positive – on tower of London test (r= 0,21) result; for risperidone also assume minor positive impact on sequence coding test (r= 0,25), but other tests in battery show no significant correlations; for zuclopenthixol we can assume minor negative impact on token motor task (r= -0,22) and verbal fluency test (r= -0,31) results. 

Abstract 363: Better Control of Blood Pressure in Midlife was Associated with Cognitive Function in Old Age: The Minabe Study in Japan

Hypertension ◽  
2013 ◽  
Vol 62 (suppl_1) ◽  
Author(s):  
Akihiko Iwahara ◽  
Yuji Uematsu ◽  
Mitsuru Siba ◽  
Nobuyuki Miyai ◽  
Mikio Arita
Keyword(s):  
Blood Pressure ◽  
Old Age ◽  
High Blood Pressure ◽  
Antihypertensive Drug ◽  
Cognitive Functions ◽  
Verbal Fluency ◽  
Memory Test ◽  
Verbal Fluency Test ◽  
Logical Memory ◽  
Fluency Test

Several studies show that hypertension in midlife is also related to cognitive impairment in old age. However, the associations between blood pressure and cognitive functions have been inconclusive. In this study, we examined this association in the sexagenarian and the septuagenarian separately to test our hypothesis that different risk factors were related to cognitive decline in each generation respectively. Participants were 1476 community-dwelling persons without dementia (708 men and 768 women). Resting systolic and diastolic blood pressures were measured in the seated position using an automated sphygmomanometer (HEM-907; Omron). The cognitive functions were measured by means of logical memory test, D-CAT (digit cancellation test; neuropsychological test for attention) and verbal fluency test. We asked participants about their use of antihypertensive drug and collected their data about blood pressure measured at a health examination conducted ten years ago. We constructed a series of multiple linear regression models to examine the association of blood pressure with each cognitive function. Separate analyses were conducted for each combination of predictor (SBP, DBP, past SBP, past DBP, and use of antihypertensive drug) and dependent value (logical memory test, D-CAT, and verbal fluency test). Regression models included the following covariates: age, education, gender, and body mass index. Results indicated the following two points: (1) Higher levels of past DBP (β = -.121, p < .05) was associated with decline in logical memory test and higher level of past SBP (β = -.127, p < .05) was associated with decline in verbal fluency test in the sexagenarian, (2) The use of antihypertensive drug was associated with decline in D-CAT (β = -.194, p < .001) and verbal fluency test (β = -.196, p < .05) in the septuagenarian. Our findings suggest that high blood pressure in the past decade is risk factor for cognitive decline in the sexagenarian but is not risk factor in the septuagenarian. The treatment of high blood pressure in midlife is important for the maintenance of cognitive functions. Early control of high blood pressure might reduce the risk of cognitive impairment in old age.

Letter Verbal Fluency in Spanish-, Basque-, and Catalan-Speaking Individuals: Does the Selection of the Letters Influence the Outcome?

2019 ◽  
Vol 62 (7) ◽  
pp. 2400-2410
Author(s):  
Laiene Olabarrieta-Landa ◽  
Itziar Benito-Sánchez ◽  
Montserrat Alegret ◽  
Anna Gailhajanet ◽  
Esther Landa Torre ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Verbal Fluency ◽  
Native Language ◽  
Spanish Speakers ◽  
Crucial Step ◽  
Verbal Fluency Test ◽  
Performance Differences ◽  
Frontal Lobe Functioning ◽  
Selection Of ◽  
Fluency Test

Purpose The aim of this study was to compare Basque and Catalan bilinguals' performance on the letter verbal fluency test and determine whether significant differences are present depending on the letters used and the language of administration. Method The sample consisted of 87 Spanish monolinguals, 139 Basque bilinguals, and 130 Catalan bilinguals from Spain. Participants completed the letter verbal fluency test using the letters F, A, S, M, R, P, and E. Results Bilinguals scored higher on the letter verbal fluency test when they were tested in Spanish than in Basque or Catalan. No performance differences were found according to native language or dialects within Basque participants. Catalans with Spanish as their native language scored lower on the letter F compared to those who grew up speaking Catalan and Spanish. The suggested letters to use with Basque speakers are A, E, and B; the suggested letters to use with Catalan speakers are P, F, and M; and the suggested letters to use with Spanish speakers are M, R, and P. Conclusion Selecting appropriate stimuli depending on the language of testing is the first crucial step to assess verbal fluency and thus possible frontal lobe functioning impairment.

Are schizophrenics neuropsychologically impaired affected psychotics? Neuropsychological performance and personality traits in relatives

2000 ◽  
Vol 12 (3) ◽  
pp. 104-104
Author(s):  
R.M. Murray ◽  
CM. Gilvarry ◽  
A. Russell ◽  
D. Hemsley
Keyword(s):  
Personality Traits ◽  
Verbal Fluency ◽  
Neuropsychological Deficits ◽  
Verbal Fluency Test ◽  
Schizophrenia Spectrum ◽  
Schizophrenic Patients ◽  
Adult Reading ◽  
Trail Making ◽  
National Adult Reading Test ◽  
Fluency Test

Neuropsychological deficits are found in both schizophrenic patients and their relatives, and some studies have shown similar, but less severe, deficits in affective psychotic patients and their relatives. We set out to establish – whether schizophrenia spectrum personality traits are more common in the relatives of schizophrenic patients than relatives of affective psychotic patients; – what is the relationship between spectrum personality traits and neuropsychological deficits in these relatives.Relatives were interviewed using the International Personality Disorder Examination (IPDE), and also completed the National Adult Reading Test (NART), the Trail Making Test (TMT: Parts A and B) and Thurstone's Verbal Fluency Test (TVFT). Spectrum personality traits were equally common in the 129 relatives of schizophrenic and 106 relatives of affective psychotic patients. Relatives of psychotic patients who themselves had high paranoid traits had lower NART scores than those without such personality traits (p=0.007);similarly, those with high schizoid personality traits took longer to complete the TMT, part B than those without such traits (p=0.0l); and relatives with high schizotypal traits generated significantly fewer words on the verbal fluency test than those without such traits (p=0.04).

scholarly journals The Modified Fuld Verbal Fluency Test: A Validation Study in Hong Kong

1997 ◽  
Vol 52B (5) ◽  
pp. P247-P250 ◽  
Author(s):  
H. F. K. Chiu ◽  
C. K. Y. Chan ◽  
L. C. W. Lam ◽  
K.-o. Ng ◽  
S.-w. Li ◽  
...  
Keyword(s):  
Hong Kong ◽  
Validation Study ◽  
Verbal Fluency ◽  
Verbal Fluency Test ◽  
Fluency Test

scholarly journals Characteristics of verbal fluency in patients with a primary episode of bipolar affective disorder

2020 ◽  
Keyword(s):  
Depressive Symptoms ◽  
Affective Disorder ◽  
Test Performance ◽  
Verbal Fluency ◽  
High Speed ◽  
Bipolar Affective Disorder ◽  
Rapid Change ◽  
Verbal Fluency Test ◽  
Manic Symptoms ◽  
Fluency Test

A study was conducted using the verbal fluency test of 153 patients with a primary episode of bipolar affective disorder: with prevalence of depressive symptoms (44 men and 75 women), with prevalence of manic symptoms (15 men and 8 women), and with simultaneous presence of depressive symptoms and manic symptoms phase change (6 men and 5 women). Significant impairment of test performance in patients with depression with respect to phonetic and semantic verbal fluency was revealed: the average number of words per letter "K" per 60 sec. in all patients 14,1±2,7 words, in men – 13,8±3,1 words, in women - 14,3±2,4 words, on the letter "P" – 12,5±2,8 respectively words, 12.3±3.2 words, 12.6±2.6 words, "Male Names" – 13.1±2.6 words respectively, 12.8±3.0 words, 13.3±2,4 words; "Fruits / furniture" – 12.0±2.4 words, 11.9±2.8 words, 12.1±2.1 words. Deterioration in the performance of semantic and phonemic verbal fluency test reflects the state of bradypsychism inherent in patients with depressive variant, which manifests a slow thinking rate, difficulty concentrating attention, motor inhibition, deterioration of operational capacity, rapid exhaustion. In patients with a maniacal variant, the high speed of the test is offset by a large number of errors due to the chaotic mental activity, instability and scattering of attention, the difficulty of maintaining focus of attention: the indicators were respectively 21.7±5.7 words, 22.5±5.7 words, 20,3±6.0 words; 20.3±5.6 words, 21.1±5.5 words, 19.0±5.9 words; 20.5±5.4 words, 21.2±5.2 words, 19.1±5.7 words; 19.5±5.4 words, 20.2±5.2 words, 18.1±5.7 words. In patients with mixed variants, the indicators of verbal fluency are reduced due to the influence of complex polymorphic symptoms with rapid change of state: respectively 16.5±5.6 words, 18.2±6.1 words, 14.4±4.8 words; 14.5±5.4 words, 16.2±5.7 words, 12.4±4.8 words; 15.4±5.4 words, 17.0±5.8 words, 13.4±4.8 words; 13.9±5.0 words, 15.5±5.3 words, 12.0±4.3 words. The differences in scores across all subtests in all groups between men and women are statistically insignificant (p>0.05).

Graph analysis of verbal fluency test discriminates between patients with bipolar disorder and healthy controls

2017 ◽  
Vol 27 ◽  
pp. S829-S830
Author(s):  
K. Machalska ◽  
A. Turek ◽  
A.A. Chrobak ◽  
A. Tereszko ◽  
M. Siwek ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Verbal Fluency ◽  
Graph Analysis ◽  
Healthy Controls ◽  
Verbal Fluency Test ◽  
Fluency Test

Neuropsychological Correlates of Greek Alcoholic Patients Who Report Memory Disturbances

2005 ◽  
Vol 96 (1) ◽  
pp. 197-203
Author(s):  
Ioannis Liappas ◽  
Ioulia Theotoka ◽  
Elisabeth Kapaki ◽  
Ioannis Ilias ◽  
George P. Paraskevas ◽  
...  
Keyword(s):  
Verbal Fluency ◽  
Digit Span ◽  
Cultural Backgrounds ◽  
Adult Intelligence Scale ◽  
Verbal Fluency Test ◽  
Wechsler Adult Intelligence Scale ◽  
Short Test ◽  
Test Category ◽  
Wechsler Adult Intelligence ◽  
Fluency Test

We studied 40 male and 37 female ( M age = 63 yr.) Greek alcoholic patients and an equal number of control subjects. Both groups were evaluated with the Mini-Mental State Examination, the Syndrome Short Test, the Verbal Fluency Test (Category & Letter), the Clock Test, and the Digit Span (Forward and Backward from the Wechsler Adult Intelligence Scale-Revised). Alcoholic patients had statistically significant lower scores on MMSE, Verbal Fluency Test, and Digit Span, and higher scores on the Syndrome Short Test, while positive correlations were found among MMSE, Verbal Fluency Test, Clock Test, Digit Span-Backward, and age. These findings point to frontal lobe dysfunction in Greek alcoholic patients which is not different from that shown in patients from diverse ethnic and cultural backgrounds.

scholarly journals P1-175: Planning the Generation of Items on the Verbal Fluency Test is Crucial to the Final Result

2011 ◽  
Vol 7 ◽  
pp. S168-S168
Author(s):  
Veronique Guernet Steiner ◽  
Mayra Jacuviske Venegas ◽  
Leticia Lessa Mansur
Keyword(s):  
Verbal Fluency ◽  
Verbal Fluency Test ◽  
Fluency Test
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