scholarly journals A Case of Severe COVID-19 in a Patient with Good's Syndrome

2021 ◽  
Author(s):  
Maria Duarte ◽  
Luciana Faria ◽  
Catarina Patronillo ◽  
Sónia da Costa Fernandes ◽  
Vera Seara
Keyword(s):  
Mediastinal Mass ◽  
Respiratory Infections ◽  
Infectious Complications ◽  
Therapeutic Strategies ◽  
Clinical Suspicion ◽  
Adult Onset ◽  
Combined Immunodeficiency ◽  
Good’S Syndrome ◽  
Recurrent Respiratory Infections ◽  
History Of

Good’s syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the clinical suspicion of Good’s syndrome. The mortality rate associated with infectious complications is high. Thus, although it is rare, the disease should be diagnosed early so that proper treatment can be started. Thymectomy and immunoglobulin replacement are the main therapeutic strategies. We describe the case of a patient with a history of thymoma and recurrent respiratory infections, with a late diagnosis of Good’s syndrome in the context of severe organizing pneumonia secondary to COVID-19.

Good's syndrome : A case with recurrent respiratory infections

2013 ◽  
Vol 24 ◽  
pp. e143
Author(s):  
S. Ersan ◽  
G. Ersan ◽  
C. Arslan ◽  
S. Atalay ◽  
S. Kose
Keyword(s):  
Respiratory Infections ◽  
Good’S Syndrome ◽  
Recurrent Respiratory Infections

scholarly journals Rheumatoid Arthritis, Kartagener’s Syndrome, and Hyperprolactinemia: Who Started It?

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Hussein Halabi ◽  
Israa Mulla
Keyword(s):  
Rheumatoid Arthritis ◽  
Dopamine Agonists ◽  
Respiratory Infections ◽  
Case Reports ◽  
Experimental Treatment ◽  
Chronic Stimulation ◽  
Recurrent Respiratory Infections ◽  
Kartagener's Syndrome ◽  
History Of ◽  
Stimulation Of

We report a case of an 18-year-old girl who presented to our hospital with history of recurrent respiratory infections, amenorrhea, and symmetric polyarthritis. She was diagnosed with rheumatoid arthritis (RA), Kartagener’s syndrome (KS), and hyperprolactinemia. There have been very few case reports in the literature of RA occurring in the setting of KS, theoretically proposed to be due to chronic stimulation of the immune system by recurrent infections. Furthermore, hyperprolactinemia has been hypothesized to mirror RA disease activity and case reports of treatment with dopamine agonists have led to the speculation of whether or not they represent a new line of experimental treatment in the future. Our patient was found to have both KS and hyperprolactinemia together in the setting of RA, and based on our literature search, this is the first reported case of such a combination. This strikes a very intriguing question: are these three conditions interlinked by a yet to be defined association? And treatment of which condition leads to the resolution of the other?

scholarly journals Unilateral pulmonary hypoplasia in an adult patient

2018 ◽  
Vol 88 (1) ◽  
Author(s):  
Dimitrios Papadopoulos ◽  
Panagiotis Misthos ◽  
Maria Chorti ◽  
Vlasios Skopas ◽  
Alexandra Nakou ◽  
...  
Keyword(s):  
Pulmonary Hypoplasia ◽  
Respiratory Infections ◽  
Imaging Technique ◽  
Lung Parenchyma ◽  
X Ray ◽  
Recurrent Respiratory Infections ◽  
Abnormal Chest ◽  
Cystic Changes ◽  
History Of ◽  
Chest X Ray

Pulmonary hypoplasia (PH) is a developmental anomaly of the lung parenchyma, characterized by a decrease in the number and size of airways, alveoli and vessels. We present a case of a 31-year-old patient with a history of chronic productive cough and frequent respiratory infections, who was referred for investigation of abnormal chest x-ray. The combination of chest computed tomography (CT) and bronchoscopy set the diagnosis of left pulmonary hypoplasia and the patient was treated surgically with a left pneumonectomy. PH is usually diagnosed immediately after birth, causing severe respiratory failure with high mortality. The less severe, unilateral forms can possibly survive by causing compensatory hyperinflation of the other lung and remain undiagnosed until adulthood, presenting either asymptomatic or with symptoms of chronic bronchitis and recurrent respiratory infections. Chest CT is considered the imaging technique of choice for the diagnosis and for the differential diagnosis from other congenital or acquired conditions. The treatment is usually conservative, although surgical resection is indicated in cases of severe cystic changes and intense symptomatology.

scholarly journals A 75-Year-Old Female with Hemoptysis and Recurrent Respiratory Infections

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Mary S. Baker ◽  
Khalil Diab
Keyword(s):  
Respiratory Infections ◽  
Interesting Case ◽  
Lung Abscess ◽  
Chest Ct ◽  
Lower Lobectomy ◽  
Recurrent Respiratory Infections ◽  
Amoxicillin Clavulanate ◽  
History Of ◽  
One Year ◽  
Multiple Episodes

This paper describes the case of a 75-year-old female who presented with significant hemoptysis over a 7–10 day period. She had a history of a left lower lobectomy 10 years prior for a “lung abscess.” She subsequently had multiple episodes of cough, fevers, and possible pneumonia treated with multiple courses of Amoxicillin and Amoxicillin/Clavulanate. Review of her chest CT upon presentation to the hospital showed a large necrotic lingular infiltrate, which had been progressively increasing in size over at least one year. Bronchoscopy showed a yellowish, soft round body in the superior lingular subsegment. Endobronchial and transbronchial biopsies showedactinomycesspecies. This is a very interesting case of indolent actinomycosis which we suspect had a very slow progressive course secondary to the multiple courses of antibiotics that the patient was treated with.

scholarly journals Unusual Detection of Tuberculosis in a Woman with Down's Syndrome

2010 ◽  
Vol 13 (1) ◽  
pp. 59-62
Author(s):  
D Pešut ◽  
S Raljević ◽  
Tomić Slijepčević
Keyword(s):  
Respiratory Infections ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Diagnostic Procedures ◽  
First Line ◽  
X Ray ◽  
Recurrent Respiratory Infections ◽  
History Of ◽  
Chest X Ray ◽  
The Right

Unusual Detection of Tuberculosis in a Woman with Down's SyndromeA woman with Down's syndrome (DS) had sub-febrile temperature, nodular/patchy shadows on the chest X-ray over the right pulmonary base, and a history of recurrent respiratory infections. She was pale, asthenic, uncommunicative, mildly anemic and the erythrocyte sedimentation rate was 80/first hour. The tuberculin skin test (TST) PPD3 was negative. Mycobacterium tuberculosis was isolated from oral mucosal brushing, sensitive to the first line anti-tuberculosis drugs. Patients with DS and other mental disabilities need special care and attention during diagnostic procedures for tuberculosis (TB).

scholarly journals Good's Syndrome: A Rare Adult-Onset Combined Immunodeficiency

2017 ◽  
Vol 139 (2) ◽  
pp. AB23
Author(s):  
Gargi Patel ◽  
Priyanka Batchu ◽  
Amay Parikh
Keyword(s):  
Adult Onset ◽  
Combined Immunodeficiency ◽  
Good’S Syndrome

scholarly journals Pulmonary Artery Sling Presenting as Pneumonia and Inhalation of a Foreign Body

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Shujuan Luo ◽  
Huaping Rao
Keyword(s):  
Pulmonary Artery ◽  
Respiratory Distress ◽  
Respiratory Infection ◽  
Respiratory Infections ◽  
Left Pulmonary Artery ◽  
Infection Prophylaxis ◽  
Pulmonary Artery Sling ◽  
Recurrent Respiratory Infections ◽  
Lower Trachea ◽  
History Of

Pulmonary artery sling is a rare cause of respiratory distress created by compression of the lower trachea and right mainstem bronchus due to an aberrant origin of the left pulmonary artery. The condition is frequently associated with recurrent respiratory infections and other congenital malformations including tracheal rings. We present the case of an infant presenting with pulmonary distress and a history of recurrent respiratory infection. The infant underwent surgery to remove a foreign object; however, the symptoms did not resolve. Bronchoscopy revealed bronchus stenosis, and subsequent echocardiogram and CT scans revealed the presence of a pulmonary artery sling. We prescribed infection prophylaxis with the immunomodulator OM-85 to mitigate the risk of further infections prior to surgery. PAS and bronchus stenosis were corrected successfully by surgical intervention leading to resolution of symptoms of respiratory distress and a reduction in the incidence of respiratory infection.

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