scholarly journals Rheumatoid Arthritis, Kartagener’s Syndrome, and Hyperprolactinemia: Who Started It?

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Hussein Halabi ◽  
Israa Mulla

We report a case of an 18-year-old girl who presented to our hospital with history of recurrent respiratory infections, amenorrhea, and symmetric polyarthritis. She was diagnosed with rheumatoid arthritis (RA), Kartagener’s syndrome (KS), and hyperprolactinemia. There have been very few case reports in the literature of RA occurring in the setting of KS, theoretically proposed to be due to chronic stimulation of the immune system by recurrent infections. Furthermore, hyperprolactinemia has been hypothesized to mirror RA disease activity and case reports of treatment with dopamine agonists have led to the speculation of whether or not they represent a new line of experimental treatment in the future. Our patient was found to have both KS and hyperprolactinemia together in the setting of RA, and based on our literature search, this is the first reported case of such a combination. This strikes a very intriguing question: are these three conditions interlinked by a yet to be defined association? And treatment of which condition leads to the resolution of the other?

2018 ◽  
Vol 88 (1) ◽  
Author(s):  
Dimitrios Papadopoulos ◽  
Panagiotis Misthos ◽  
Maria Chorti ◽  
Vlasios Skopas ◽  
Alexandra Nakou ◽  
...  

Pulmonary hypoplasia (PH) is a developmental anomaly of the lung parenchyma, characterized by a decrease in the number and size of airways, alveoli and vessels. We present a case of a 31-year-old patient with a history of chronic productive cough and frequent respiratory infections, who was referred for investigation of abnormal chest x-ray. The combination of chest computed tomography (CT) and bronchoscopy set the diagnosis of left pulmonary hypoplasia and the patient was treated surgically with a left pneumonectomy. PH is usually diagnosed immediately after birth, causing severe respiratory failure with high mortality. The less severe, unilateral forms can possibly survive by causing compensatory hyperinflation of the other lung and remain undiagnosed until adulthood, presenting either asymptomatic or with symptoms of chronic bronchitis and recurrent respiratory infections. Chest CT is considered the imaging technique of choice for the diagnosis and for the differential diagnosis from other congenital or acquired conditions. The treatment is usually conservative, although surgical resection is indicated in cases of severe cystic changes and intense symptomatology.


2016 ◽  
Vol 70 (6) ◽  
pp. 31-39 ◽  
Author(s):  
Jarosław Paśnik

Recurrent respiratory tract infections in children are the most common cause of outpatient visits. Due to the necessity of treatment of chronic, frequent use of antibiotics and the dangers of complications are a major clinical problem. Big hopes are now with the possibility of the use of immunostimulation as prevention of these infections. The paper discusses the most important methods of stimulation of the immune system in children. In the light of previous reports were evaluated effects of this type of therapy.


2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Mary S. Baker ◽  
Khalil Diab

This paper describes the case of a 75-year-old female who presented with significant hemoptysis over a 7–10 day period. She had a history of a left lower lobectomy 10 years prior for a “lung abscess.” She subsequently had multiple episodes of cough, fevers, and possible pneumonia treated with multiple courses of Amoxicillin and Amoxicillin/Clavulanate. Review of her chest CT upon presentation to the hospital showed a large necrotic lingular infiltrate, which had been progressively increasing in size over at least one year. Bronchoscopy showed a yellowish, soft round body in the superior lingular subsegment. Endobronchial and transbronchial biopsies showedactinomycesspecies. This is a very interesting case of indolent actinomycosis which we suspect had a very slow progressive course secondary to the multiple courses of antibiotics that the patient was treated with.


2015 ◽  
pp. bcr2015211650
Author(s):  
Cecilia Ronnevi ◽  
Cristian Ortiz-Villalon ◽  
Jacek Pawlowski ◽  
Giovanni Ferrara

2020 ◽  
Vol 13 (2) ◽  
pp. 100-109
Author(s):  
Eka Nurhayati ◽  
Arum Pratiwi

Introduction: Coronavirus is a collection of viruses that can infect the respiratory system. In many cases, this virus only causes mild respiratory infections, such as flu. However, this virus can also cause severe respiratory infections, such as lung infections (pneumonia). The method is a literature review research in the form of case reports through the search of accredited journal sites such as Scientdirect and Elsevier with the keyword COVID-19 pneumonia in the period of 2015-2020. Research Results: in handling COVID-19 cases each country has its own way which consists of a physical examination, blood laboratory examination, chest CT scan, swab test, urine test, oxygen installation, mechanical ventilation, Extracorporeal Membrane Oxygention (ECMO) ), as well as the administration of drugs Ceftriaxone, Azithromycin, Piramivir, iopinavir-Ritonavir, Nafamostat and Intravenous Immune Globulin (IVIG), each patient differs based on history of illness. Conclusion: every region and every country has its own way of handling COVID-19 cases because until now there has been no definitive treatment or vaccine that can treat cases of COVID-19 that have struck all over the world.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Hamza Dergamoun ◽  
Abdelilah El Alaoui ◽  
Imad Boualaoui ◽  
Hachem Sayegh ◽  
Lounis Benslimane ◽  
...  

Background. The association of renal cell carcinoma and Kartagener’s syndrome is unusual, and only eleven cases have been reported in the literature. The purpose of this work is to analyze this unusual association of Kartagener’s syndrome and renal cell tumor and to study the main diagnostic and therapeutic aspects through our observation and review of the literature. Case Presentation. We report the case of a 50-year-old patient, with a history of recurrent respiratory infections, in whom a renal tumor was simultaneously diagnosed with Kartagener’s syndrome, represented by situs inversus, bronchiectasia, and chronic sinusitis. The patient was treated by partial nephrectomy, and the histological examination showed a clear cell carcinoma. Through this observation and a review of the literature, we try to analyze this association as well as the main diagnostic and therapeutic aspects. Conclusion. The association of situs inversus and renal cell carcinoma is very rare—preoperative assessment and anatomy knowledge are crucial for a better adaptation of the surgical technique.


2010 ◽  
Vol 13 (1) ◽  
pp. 59-62
Author(s):  
D Pešut ◽  
S Raljević ◽  
Tomić Slijepčević

Unusual Detection of Tuberculosis in a Woman with Down's SyndromeA woman with Down's syndrome (DS) had sub-febrile temperature, nodular/patchy shadows on the chest X-ray over the right pulmonary base, and a history of recurrent respiratory infections. She was pale, asthenic, uncommunicative, mildly anemic and the erythrocyte sedimentation rate was 80/first hour. The tuberculin skin test (TST) PPD3 was negative. Mycobacterium tuberculosis was isolated from oral mucosal brushing, sensitive to the first line anti-tuberculosis drugs. Patients with DS and other mental disabilities need special care and attention during diagnostic procedures for tuberculosis (TB).


Author(s):  
Maria Duarte ◽  
Luciana Faria ◽  
Catarina Patronillo ◽  
Sónia da Costa Fernandes ◽  
Vera Seara

Good’s syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the clinical suspicion of Good’s syndrome. The mortality rate associated with infectious complications is high. Thus, although it is rare, the disease should be diagnosed early so that proper treatment can be started. Thymectomy and immunoglobulin replacement are the main therapeutic strategies. We describe the case of a patient with a history of thymoma and recurrent respiratory infections, with a late diagnosis of Good’s syndrome in the context of severe organizing pneumonia secondary to COVID-19.


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