Immunoglobulin G Deficiency in Children with Recurrent Respiratory Infections with and Without History of Allergy

We report a case of an 18-year-old girl who presented to our hospital with history of recurrent respiratory infections, amenorrhea, and symmetric polyarthritis. She was diagnosed with rheumatoid arthritis (RA), Kartagener’s syndrome (KS), and hyperprolactinemia. There have been very few case reports in the literature of RA occurring in the setting of KS, theoretically proposed to be due to chronic stimulation of the immune system by recurrent infections. Furthermore, hyperprolactinemia has been hypothesized to mirror RA disease activity and case reports of treatment with dopamine agonists have led to the speculation of whether or not they represent a new line of experimental treatment in the future. Our patient was found to have both KS and hyperprolactinemia together in the setting of RA, and based on our literature search, this is the first reported case of such a combination. This strikes a very intriguing question: are these three conditions interlinked by a yet to be defined association? And treatment of which condition leads to the resolution of the other?

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Unilateral pulmonary hypoplasia in an adult patient

Monaldi Archives for Chest Disease ◽

10.4081/monaldi.2018.829 ◽

2018 ◽

Vol 88 (1) ◽

Author(s):

Dimitrios Papadopoulos ◽

Panagiotis Misthos ◽

Maria Chorti ◽

Vlasios Skopas ◽

Alexandra Nakou ◽

...

Keyword(s):

Pulmonary Hypoplasia ◽

Respiratory Infections ◽

Imaging Technique ◽

Lung Parenchyma ◽

X Ray ◽

Recurrent Respiratory Infections ◽

Abnormal Chest ◽

Cystic Changes ◽

History Of ◽

Chest X Ray

Pulmonary hypoplasia (PH) is a developmental anomaly of the lung parenchyma, characterized by a decrease in the number and size of airways, alveoli and vessels. We present a case of a 31-year-old patient with a history of chronic productive cough and frequent respiratory infections, who was referred for investigation of abnormal chest x-ray. The combination of chest computed tomography (CT) and bronchoscopy set the diagnosis of left pulmonary hypoplasia and the patient was treated surgically with a left pneumonectomy. PH is usually diagnosed immediately after birth, causing severe respiratory failure with high mortality. The less severe, unilateral forms can possibly survive by causing compensatory hyperinflation of the other lung and remain undiagnosed until adulthood, presenting either asymptomatic or with symptoms of chronic bronchitis and recurrent respiratory infections. Chest CT is considered the imaging technique of choice for the diagnosis and for the differential diagnosis from other congenital or acquired conditions. The treatment is usually conservative, although surgical resection is indicated in cases of severe cystic changes and intense symptomatology.

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A 75-Year-Old Female with Hemoptysis and Recurrent Respiratory Infections

Case Reports in Critical Care ◽

10.1155/2013/832306 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3

Author(s):

Mary S. Baker ◽

Khalil Diab

Keyword(s):

Respiratory Infections ◽

Interesting Case ◽

Lung Abscess ◽

Chest Ct ◽

Lower Lobectomy ◽

Recurrent Respiratory Infections ◽

Amoxicillin Clavulanate ◽

History Of ◽

One Year ◽

Multiple Episodes

This paper describes the case of a 75-year-old female who presented with significant hemoptysis over a 7–10 day period. She had a history of a left lower lobectomy 10 years prior for a “lung abscess.” She subsequently had multiple episodes of cough, fevers, and possible pneumonia treated with multiple courses of Amoxicillin and Amoxicillin/Clavulanate. Review of her chest CT upon presentation to the hospital showed a large necrotic lingular infiltrate, which had been progressively increasing in size over at least one year. Bronchoscopy showed a yellowish, soft round body in the superior lingular subsegment. Endobronchial and transbronchial biopsies showedactinomycesspecies. This is a very interesting case of indolent actinomycosis which we suspect had a very slow progressive course secondary to the multiple courses of antibiotics that the patient was treated with.

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Microcephaly and a History of Recurrent Respiratory Infections

Pediatric Immunology ◽

10.1007/978-3-030-21262-9_125 ◽

2019 ◽

pp. 677-682

Author(s):

Anastasiia Bondarenko

Keyword(s):

Respiratory Infections ◽

Recurrent Respiratory Infections ◽

History Of

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Unusual Detection of Tuberculosis in a Woman with Down's Syndrome

Balkan Journal of Medical Genetics ◽

10.2478/v10034-010-0021-9 ◽

2010 ◽

Vol 13 (1) ◽

pp. 59-62

Author(s):

D Pešut ◽

S Raljević ◽

Tomić Slijepčević

Keyword(s):

Respiratory Infections ◽

Down's Syndrome ◽

Down’S Syndrome ◽

Diagnostic Procedures ◽

First Line ◽

X Ray ◽

Recurrent Respiratory Infections ◽

History Of ◽

Chest X Ray ◽

The Right

Unusual Detection of Tuberculosis in a Woman with Down's SyndromeA woman with Down's syndrome (DS) had sub-febrile temperature, nodular/patchy shadows on the chest X-ray over the right pulmonary base, and a history of recurrent respiratory infections. She was pale, asthenic, uncommunicative, mildly anemic and the erythrocyte sedimentation rate was 80/first hour. The tuberculin skin test (TST) PPD3 was negative. Mycobacterium tuberculosis was isolated from oral mucosal brushing, sensitive to the first line anti-tuberculosis drugs. Patients with DS and other mental disabilities need special care and attention during diagnostic procedures for tuberculosis (TB).

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A Case of Severe COVID-19 in a Patient with Good's Syndrome

European Journal of Case Reports in Internal Medicine ◽

10.12890/2021_002976 ◽

2021 ◽

Author(s):

Maria Duarte ◽

Luciana Faria ◽

Catarina Patronillo ◽

Sónia da Costa Fernandes ◽

Vera Seara

Keyword(s):

Mediastinal Mass ◽

Respiratory Infections ◽

Infectious Complications ◽

Therapeutic Strategies ◽

Clinical Suspicion ◽

Adult Onset ◽

Combined Immunodeficiency ◽

Good’S Syndrome ◽

Recurrent Respiratory Infections ◽

History Of

Good’s syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the clinical suspicion of Good’s syndrome. The mortality rate associated with infectious complications is high. Thus, although it is rare, the disease should be diagnosed early so that proper treatment can be started. Thymectomy and immunoglobulin replacement are the main therapeutic strategies. We describe the case of a patient with a history of thymoma and recurrent respiratory infections, with a late diagnosis of Good’s syndrome in the context of severe organizing pneumonia secondary to COVID-19.

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Pulmonary Artery Sling Presenting as Pneumonia and Inhalation of a Foreign Body

Case Reports in Infectious Diseases ◽

10.1155/2019/8912136 ◽

2019 ◽

Vol 2019 ◽

pp. 1-4

Author(s):

Shujuan Luo ◽

Huaping Rao

Keyword(s):

Pulmonary Artery ◽

Respiratory Distress ◽

Respiratory Infection ◽

Respiratory Infections ◽

Left Pulmonary Artery ◽

Infection Prophylaxis ◽

Pulmonary Artery Sling ◽

Recurrent Respiratory Infections ◽

Lower Trachea ◽

History Of

Pulmonary artery sling is a rare cause of respiratory distress created by compression of the lower trachea and right mainstem bronchus due to an aberrant origin of the left pulmonary artery. The condition is frequently associated with recurrent respiratory infections and other congenital malformations including tracheal rings. We present the case of an infant presenting with pulmonary distress and a history of recurrent respiratory infection. The infant underwent surgery to remove a foreign object; however, the symptoms did not resolve. Bronchoscopy revealed bronchus stenosis, and subsequent echocardiogram and CT scans revealed the presence of a pulmonary artery sling. We prescribed infection prophylaxis with the immunomodulator OM-85 to mitigate the risk of further infections prior to surgery. PAS and bronchus stenosis were corrected successfully by surgical intervention leading to resolution of symptoms of respiratory distress and a reduction in the incidence of respiratory infection.

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Sonographic Criteria for Diagnosing Jarcho-Levin Syndrome

Journal of Diagnostic Medical Sonography ◽

10.1177/8756479317733730 ◽

2017 ◽

Vol 34 (1) ◽

pp. 53-57

Author(s):

Terrie Lutke

Keyword(s):

Family History ◽

Respiratory Insufficiency ◽

Autosomal Recessive ◽

Respiratory Infections ◽

Genetic Disorder ◽

Spinal Column ◽

Dominant Trait ◽

Recurrent Respiratory Infections ◽

History Of

This is a case study of Jarcho-Levin syndrome, which is a rare genetic disorder described as a malformation of bones in the spinal column and the ribs. This disorder can be an autosomal recessive or dominant trait. Those affected by this disorder have respiratory insufficiency and potentially other abnormalities. Recurrent respiratory infections are expected. In milder cases, surgery is a possibility, but in severe cases, prognosis is poor. OB sonography can aid in diagnosis of Jarcho-Levin syndrome in patients with no known family history of the disease, but it is particularly helpful in known at-risk cases.

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PERAN IBU DALAM PENINGKATAN SISTEM IMUN ANAK DENGAN INFEKSI SALURAN PERNAFASAN AKUT

Jurnal Keperawatan ◽

10.32583/keperawatan.v11i2.422 ◽

2019 ◽

Vol 11 (2) ◽

pp. 79-86

Author(s):

Cindy Ayustin Noya ◽

Angkit Kinasih ◽

Venti Agustina ◽

R.Rr Maria Dyah Kurniasari

Keyword(s):

Immune System ◽

Acute Respiratory Infection ◽

Lower Respiratory Tract ◽

Research Method ◽

Respiratory Infections ◽

Acute Respiratory Infections ◽

Clean Environment ◽

History Of ◽

Qualitative Descriptive

Infeksi saluran pernafasan akut atau yang sering disebut ISPA merupakan infeksi pada saluran pernafasan baik saluran pernafasan atas atau bawah.ISPA juga kebanyakan terjadi pada anak balita karena daya tahan tubuh mereka tidak kuat dalam menghadapi penyakit ISPA. ISPA mengakibatkan kematiansekitar15%-20% per tahun pada usia balita di Negara berkembang. Tujuan penelitian ini adalah untuk mengetahui dan menganalisa peran ibu dalam meningkatkan sistem imun anak dengan ISPA.Metode penelitian yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan sampel purposive sampling.Populasi dan sampel penelitian ini adalah ibu yang mempunyai anak dengan riwayat dan saat ini menderita penyakit ISPA di Batu Gajah Kota Ambon.Partisipan dalam penelitian ini berjumlah 5 orang. Hasil dari penelitian mendapati 4 kategori yaitu pemberian nutrisi pada anak untuk memenuhi kebutuhan agar sistem imunnya terjaga, kebersihan lingkungan, peran ibu dalam melakukan pencegahan pada anaknya yang mengalami ISPA, dan peran ibu dalam menjaga dan mempertahankan kesehatan anaknya. Kata kunci: peran ibu, sistem imun, ispa THE ROLE OF MOTHERS IN INCREASING IMMUNE SYSTEM OF CHILDREN WITH ACUTE RESPIRATORY INFECTION ABSTRACT Acute respiratory infections or often called ARI is an infection of the upper or lower respiratory tract. ARI occurs mostly in children under the age of five because their endurance is not strong in dealing with ARI. ARI results in deaths of around 15%-20% per year at the age of under-five in developing countries. The purpose of this study was to determine and analyze the role of mothers in improving the immune system of children against ARI. The research method used in this study was qualitative descriptive with a purposive sampling sample. Respondents and samples of this study were five mothers who had children with a history of ARI and currently suffering from the disease in Batu Gajah, Ambon City. The results of the study found 4 categories, namely providing nutrition to children to meet their needs so that their immune systems are maintained, clean environment, mother's role in preventing children with ARI, and mother's role to preserve and maintain the health of their children. The findings indicated that in terms of coping or improving the immune system of a child to avoid ARI, it is necessary to have role the of mothers in providing nutrition so that the immune system is boosted, besides that the mother can prevent and protect her child from various diseases, especially ARI. Keywords: role of mothers, immune system, acute respiratory infections

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