scholarly journals FREQUENCY ANALYSIS OF CARDIAC DATA OBTAINED THROUGH HOLTER MONITORING IN REAL LIVING CONDITIONS

2019 ◽  
Vol 7 ◽  
pp. 870-874
Author(s):  
Galya Nikolova Georgieva-Tsaneva
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Scientific Literature ◽  
Real Life ◽  
Low Frequency ◽  
Holter Monitoring ◽  
Heart Rate Variability Analysis ◽  
Healthy Individuals ◽  
Spectral Parameters

The paper presents frequency methods for estimating the variability of intervals between individual heart beats in Electrocardiogram. This parameter is known in the scientific literature as the Heart Rate Variability and with this method it is possible to make predictions about human health. Three frequency ranges have been studied: Very Low Frequency, Low Frequency, and High Frequency. The study in this paper was based on real cardiological data obtained from 33 patients suffering from heart fibrillations and 29 healthy individuals. The investigated records are obtained through a Holter monitoring of studied individuals in real life conditions. The obtained results show significantly lower values ​​of the tested spectral parameters in the diseased individuals compared to the healthy controls. The accomplished study shows the effective applicability of the spectral methods of Heart Rate Variability analysis and the possibility of differentiation by the spectral parameters of the patients from healthy individuals.

scholarly journals Clinical significance of heart rate variability and Q-T interval duration during Holter monitoring of ECG in patients with essential hypertension

2004 ◽  
Vol 10 (1) ◽  
pp. 39-42
Author(s):  
A. V. Shabalin ◽  
Ye. N. Gulyaeva ◽  
Ye. Ye. Torochkina ◽  
E. M. Verkoshanskaya ◽  
O. V. Kovalenko ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Essential Hypertension ◽  
Clinical Significance ◽  
Comparison Group ◽  
Low Frequency ◽  
Holter Monitoring ◽  
Total Power ◽  
Interval Duration ◽  
Healthy Individuals

The clinical significance of heart rate variability and Q-T interval duration during 24-hour bifunctional monitoring of ECG and blood pressure (BP) was studied in 81 patients aged 22-58 years (mean 41,40±0,72 years) who had Stages I-III essential hypertension (EH). A comparison group included 20 healthy individuals. Temporary and spectral methods were used to assess the parameters of heart rate variability; 24-hour Q-Tand O-Tk intervals, as well as echocardiographic data were analyzed. Patients with Stages I-III EH were ascertained to have a progressive decrease in diurnal heart rate variability along with a reduction in the total power of the spectrum, in the power of low-frequency constituents, and in their ratio. EH progression was found to be associated with an increase in the duration of the Q-T interval, its corrected values during daylight hours and with the degree of heart rate variability without circadian changes. The degree of autonomous cardiac control was statistically significantly related to heart rate variability and a risk for ventricular repolarization disorders.

Validity of a Smartphone Application and Chest Strap for Recording RR Intervals at Rest in Athletes

2020 ◽  
Vol 15 (6) ◽  
pp. 896-899
Author(s):  
Reabias de A. Pereira ◽  
José Luiz de B. Alves ◽  
João Henrique da C. Silva ◽  
Matheus da S. Costa ◽  
Alexandre S. Silva
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Frequency Domain ◽  
Time Domain ◽  
High Frequency ◽  
Low Frequency ◽  
Smartphone Application ◽  
Smartphone App ◽  
Heart Rate Variability Analysis ◽  
Rr Intervals

Objective: To evaluate the accuracy of the smartphone application (app) HRV Expert (CardioMood) and a chest strap (H10 Polar) for recording R-R intervals compared with electrocardiogram (ECG). Methods: A total of 31 male recreational runners (age 36.1 [6.3] y) volunteered for this study. R-R intervals were recorded simultaneously by the smartphone app and ECG for 5 minutes to analyze heart-rate variability in both the supine and sitting positions. Time-domain indexes (heart rate, mean R-R, SD of RR intervals, count of successive normal R-R intervals differing by more than 50 ms, percentage of successive normal R-R intervals differing by more than 50 ms, and root mean square of successive differences between normal R-R intervals), frequency-domain indexes (low frequency, normalized low frequency, high frequency, normalized high frequency, low-frequency to high-frequency ratio, and very low frequency), and nonlinear indexes (SD of instantaneous beat-to-beat variability and long-term SD of continuous R-R intervals) were compared by unpaired t test, Pearson correlation, simple linear regression, and Bland–Altman plot to evaluate the agreement between the devices. Results: High similarity with P value varying between .97 and 1.0 in both positions was found. The correlation coefficient of the heart-rate-variability indexes was perfect (r = 1.0; P = .00) for all variables. The constant error, standard error of estimation, and limits of agreement between ECG and the smartphone app were considered small. Conclusion: The smartphone app and chest strap provide excellent ECG compliance for all variables in the time domain, frequency domain, and nonlinear indexes, regardless of the assessed position. Therefore, the smartphone app replaces ECG for any heart-rate-variability analysis in runners.

scholarly journals The Influence ofNrf2on Cardiac Responses to Environmental Stressors

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Reuben Howden ◽  
Eva Gougian ◽  
Marcus Lawrence ◽  
Samantha Cividanes ◽  
Wesley Gladwell ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Low Frequency ◽  
Therapeutic Strategies ◽  
Environmental Stressors ◽  
Total Power ◽  
Airborne Pollutants ◽  
Cardiac Responses

Nrf2protects the lung from adverse responses to oxidants, including 100% oxygen (hyperoxia) and airborne pollutants like particulate matter (PM) exposure, but the role ofNrf2on heart rate (HR) and heart rate variability (HRV) responses is not known. We hypothesized that genetic disruption ofNrf2would exacerbate murine HR and HRV responses to severe hyperoxia or moderate PM exposures.Nrf2-/-andNrf2+/+mice were instrumented for continuous ECG recording to calculate HR and HRV (low frequency (LF), high frequency (HF), and total power (TP)). Mice were then either exposed to hyperoxia for up to 72 hrs or aspirated with ultrafine PM (UF-PM). Compared to respective controls, UF-PM induced significantly greater effects on HR (P<0.001) and HF HRV (P<0.001) inNrf2-/-mice compared toNrf2+/+mice.Nrf2-/-mice tolerated hyperoxia significantly less thanNrf2+/+mice (~22 hrs;P<0.001). Reductions in HR, LF, HF, and TP HRV were also significantly greater inNrf2-/-compared toNrf2+/+mice (P<0.01). Results demonstrate thatNrf2deletion increases susceptibility to change in HR and HRV responses to environmental stressors and suggest potential therapeutic strategies to prevent cardiovascular alterations.

scholarly journals Effect of Acupuncture on Heart Rate Variability: A Systematic Review

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Joanne W. Y. Chung ◽  
Vincent C. M. Yan ◽  
Hongwei Zhang
Keyword(s):  
Systematic Review ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Healthy Subjects ◽  
Keyword Search ◽  
Data Extraction ◽  
Meta Analysis ◽  
Low Frequency ◽  
Control Group

Aim.To summarize all relevant trials and critically evaluate the effect of acupuncture on heart rate variability (HRV).Method.This was a systematic review with meta-analysis. Keyword search was conducted in 7 databases for randomized controlled trials (RCTs). Data extraction and risk of bias were done.Results.Fourteen included studies showed a decreasing effect of acupuncture on low frequency (LF) and low frequency to high frequency ratio (LF/HF ratio) of HRV for nonhealthy subjects and on normalized low frequency (LF norm) for healthy subjects. The overall effect was in favour of the sham/control group for high frequency (HF) in nonhealthy subjects and for normalized high frequency (HF norm) in healthy subjects. Significant decreasing effect on HF and LF/HF ratio of HRV when acupuncture was performed on ST36 among healthy subjects and PC6 among both healthy and nonhealthy subjects, respectively.Discussion.This study partially supports the possible effect of acupuncture in modulating the LF of HRV in both healthy and nonhealthy subjects, while previous review reported that acupuncture did not have any convincing effect on HRV in healthy subjects. More published work is needed in this area to determine if HRV can be an indicator of the therapeutic effect of acupuncture.

Modulation of Neurocardiac Function by Oesophageal Stimulation in Humans

1997 ◽  
Vol 92 (2) ◽  
pp. 167-174 ◽  
Author(s):  
Gervais Tougas ◽  
Markad Kamath ◽  
Geena Watteel ◽  
Debbie Fitzpatrick ◽  
Ernest L. Fallen ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Power Spectrum ◽  
High Frequency ◽  
Low Frequency ◽  
Sensory Stimulation ◽  
Sensory Stimuli ◽  
Autonomic Reflexes ◽  
Low Frequency Power ◽  
Beat Heart

1. The heart and the oesophagus have similar sensory pathways, and sensations originating from the oesophagus are often difficult to differentiate from those of cardiac origin. We hypothesized that oesophageal sensory stimuli could alter neurocardiac function through autonomic reflexes elicited by these oesophageal stimuli. In the present study, we examined the neurocardiac response to oesophageal stimulation and the effects of electrical and mechanical oesophageal stimulation on the power spectrum of beat-to-beat heart rate variability in male volunteers. 2. In 14 healthy volunteers, beat-to-beat heart rate variability was compared at rest and during oesophageal stimulation, using either electrical (200 μs, 16 mA, 0.2 Hz) or mechanical (0.5 s, 14 ml, 0.2 Hz) stimuli. The power spectrum of beat-to-beat heart rate variability was obtained and its low- and high-frequency components were determined. 3. Distal oesophageal stimulation decreased heart rate slightly (both electrical and mechanical) (P < 0.005), and markedly altered heart rate variability (P < 0.001). Both electrical and mechanical oesophageal stimulation increased the absolute and normalized area of the high-frequency band within the power spectrum (P < 0.001), while simultaneously decreasing the low-frequency power (P < 0.005). 4. In humans, oesophageal stimulation, whether electrical or mechanical, appears to amplify respiratory-driven cardiac vagoafferent modulation while decreasing sympathetic modulation. The technique provides access to vagoafferent fibres and thus may yield useful information on the autonomic effects of visceral or oesophageal sensory stimulation.

Effect of fingolimod on cardiac autonomic regulation in patients with multiple sclerosis

2015 ◽  
Vol 22 (8) ◽  
pp. 1080-1085 ◽  
Author(s):  
Sakari Simula ◽  
Tomi Laitinen ◽  
Tiina M Laitinen ◽  
Tuula Tarkiainen ◽  
Päivi Hartikainen ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Frequency Ratio ◽  
Low Frequency ◽  
Autonomic Regulation ◽  
Rr Interval ◽  
Cardiac Autonomic Regulation ◽  
Multiple Sclerosis Patients

Background: Fingolimod modulates sphingosine-1-phosphate receptors that are also found in cardiovascular tissue. Objective: To investigate the effects of fingolimod on cardiac autonomic regulation prospectively. Methods: Twenty-seven relapsing–remitting multiple sclerosis patients underwent 24-hour electrocardiogram recording before, at the first day of fingolimod treatment (1d) and after three months of continuous dosing (3mo). The time interval between two consecutive R-peaks (RR-interval) was measured. Cardiac autonomic regulation was assessed by the various parameters of heart rate variability. Parasympathetic stimulation prolongs the RR-interval and increases heart rate variability while the effects of sympathetic stimulation are mainly the opposite. The low frequency/high frequency ratio reflects sympathovagal balance. Results: From baseline to 1d, a prolongation of the RR-interval ( P<0.001), an increase in the values of various heart rate variability parameters ( P<0.05 to P<0.001) and a decrease in the low frequency/high frequency ratio ( P<0.05) were demonstrated. At 3mo, although the RR-interval remained longer ( P<0.01), the values of various heart rate variability parameters were lower ( P<0.01 to P<0.001) as compared to baseline. At 3mo, the low frequency/high frequency ratio ( P<0.05) was higher in men than in women although no such difference was found at baseline or at 1d. Conclusions: After an initial increase in parasympathetic regulation, continuous fingolimod dosing shifts cardiac autonomic regulation towards sympathetic predominance, especially in men. Careful follow-up of fingolimod-treated relapsing–remitting multiple sclerosis patients is warranted as sympathetic predominance associates generally with impaired outcome. ClinicalTrials.cov: NCT01704183

Mind–body interactive qigong improves physical and mental aspects of quality of life in inpatients with stroke: A randomized control study

2019 ◽  
Vol 18 (8) ◽  
pp. 658-666 ◽  
Author(s):  
Ching-Hsiang Chen ◽  
Kuo-Sheng Hung ◽  
Yu-Chu Chung ◽  
Mei-Ling Yeh
Keyword(s):  
Quality Of Life ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Standard Care ◽  
Low Frequency ◽  
Control Group ◽  
Subacute Stroke ◽  
Interactive Exercise

Background: Stroke, a medical condition that causes physical disability and mental health problems, impacts negatively on quality of life. Post-stroke rehabilitation is critical to restoring quality of life in these patients. Objectives: This study was designed to evaluate the effect of a mind–body interactive qigong intervention on the physical and mental aspects of quality of life, considering bio-physiological and mental covariates in subacute stroke inpatients. Methods: A randomized controlled trial with repeated measures design was used. A total of 68 participants were recruited from the medical and rehabilitation wards at a teaching hospital in northern Taiwan and then randomly assigned either to the Chan-Chuang qigong group, which received standard care plus a 10-day mind–body interactive exercise program, or to the control group, which received standard care only. Data were collected using the National Institutes of Health Stroke Scale, Hospital Anxiety and Depression Scale, Short Form-12, stroke-related neurologic deficit, muscular strength, heart rate variability and fatigue at three time points: pre-intervention, halfway through the intervention (day 5) and on the final day of the intervention (day 10). Results: The results of the mixed-effect model analysis showed that the qigong group had a significantly higher quality of life score at day 10 ( p<0.05) than the control group. Among the covariates, neurologic deficit ( p=0.04), muscle strength ( p=0.04), low frequency to high frequency ratio ( p=0.02) and anxiety ( p=0.04) were significantly associated with changes in quality of life. Conversely, heart rate, heart rate variability (standard deviation of normal-to-normal intervals, low frequency and high frequency), fatigue and depression were not significantly associated with change in quality of life ( p >0.05). Conclusions: This study supports the potential benefits of a 10-day mind–body interactive exercise (Chan-Chuang qigong) program for subacute stroke inpatients and provides information that may be useful in planning adjunctive rehabilitative care for stroke inpatients.

scholarly journals Correction: MRI-related anxiety in healthy individuals, intrinsic BOLD oscillations at 0.1 Hz in precentral gyrus and insula, and heart rate variability in low frequency bands

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216731
Author(s):  
Gert Pfurtscheller ◽  
Andreas Schwerdtfeger ◽  
David Fink ◽  
Clemens Brunner ◽  
Christoph Stefan Aigner ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Low Frequency ◽  
Precentral Gyrus ◽  
Healthy Individuals ◽  
Frequency Bands

Elevated heart rate variability in physically active postmenopausal women: a cardioprotective effect?

1996 ◽  
Vol 271 (2) ◽  
pp. H455-H460 ◽  
Author(s):  
K. P. Davy ◽  
N. L. Miniclier ◽  
J. A. Taylor ◽  
E. T. Stevenson ◽  
D. R. Seals
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Postmenopausal Women ◽  
High Frequency ◽  
Low Frequency ◽  
Total Power ◽  
High Frequency Power ◽  
Fat Percentage ◽  
Physically Active ◽  
Frequency Power

Coronary heart disease (CHD) and cardiac sudden death (CSD) incidence accelerates after menopause, but the incidence is lower in physically active versus less active women. Low heart rate variability (HRV) is a risk factor for CHD and CSD. The purpose of the present investigation was to test the hypothesis that HRV at rest is greater in physically active compared with less active postmenopausal women. If true, we further hypothesized that the greater HRV in the physically active women would be closely associated with an elevated spontaneous cardiac baroreflex sensitivity (SBRS). HRV (both time and frequency domain measures) and SBRS (sequence method) were measured during 5-min periods of controlled frequency breathing (15 breaths/min) in the supine, sitting, and standing postures in 9 physically active postmenopausal women (age = 53 +/- 1 yr) and 11 age-matched controls (age = 56 +/- 2 yr). Body weight, body mass index, and body fat percentage were lower (P < 0.01) and maximal oxygen uptake was higher (P < 0.01) in the physically active group. The standard deviation of the R-R intervals (time domain measure) was higher in all postures in the active women (P < 0.05) as were the high-frequency, low-frequency, and total power of HRV. SBRS also was higher (P < 0.05) in the physically active women in all postures and accounted for approximately 70% of the variance in the high-frequency power of HRV (P < 0.05). The results of the present investigation indicate that physically active postmenopausal women demonstrate higher levels of HRV compared with age-matched, less active women. Furthermore, SBRS accounted for the majority of the variance in the high-frequency power of HRV, suggesting the possibility of a mechanistic link with cardiac vagal modulation of heart rate. Our findings may provide insight into a possible cardioprotective mechanism in physically active postmenopausal women.

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