Correction: MRI-related anxiety in healthy individuals, intrinsic BOLD oscillations at 0.1 Hz in precentral gyrus and insula, and heart rate variability in low frequency bands

The paper presents frequency methods for estimating the variability of intervals between individual heart beats in Electrocardiogram. This parameter is known in the scientific literature as the Heart Rate Variability and with this method it is possible to make predictions about human health. Three frequency ranges have been studied: Very Low Frequency, Low Frequency, and High Frequency. The study in this paper was based on real cardiological data obtained from 33 patients suffering from heart fibrillations and 29 healthy individuals. The investigated records are obtained through a Holter monitoring of studied individuals in real life conditions. The obtained results show significantly lower values of the tested spectral parameters in the diseased individuals compared to the healthy controls. The accomplished study shows the effective applicability of the spectral methods of Heart Rate Variability analysis and the possibility of differentiation by the spectral parameters of the patients from healthy individuals.

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The Relationship Between Spectral Changes in Heart Rate Variability and Fatigue

Journal of Psychophysiology ◽

10.1027/0269-8803.23.3.143 ◽

2009 ◽

Vol 23 (3) ◽

pp. 143-151 ◽

Cited By ~ 36

Author(s):

Yvonne Tran ◽

Nirupama Wijesuriya ◽

Mika Tarvainen ◽

Pasi Karjalainen ◽

Ashley Craig

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Low Frequency ◽

Chronic Fatigue ◽

Common Symptom ◽

Healthy Individuals ◽

Spectral Changes ◽

Fatigue Syndrome ◽

Experienced Fatigue ◽

Sympathetic Arousal

Fatigue is a prevalent problem in the workplace and a common symptom of many diseases. However, its relationship with the autonomic nervous system, specifically with sympathetic arousal, needs clarification. The objective of this study was to determine the association between fatigue and heart rate variability (HRV). HRV is regarded as an indicator of the autonomic regulation activity of heart rate, specifically sympathetic and parasympathetic activity. Spectral changes in low-frequency (LF; 0.04–0.15 Hz) and high-frequency (HF; 0.15–0.4 Hz) components of HRV have been reported to be associated with distressing conditions such as hemorrhagic shock, acute myocardial infarction, elevated anxiety, and depressed mood. While HRV changes have been found in persons with chronic fatigue syndrome, its association with fatigue in healthy individuals still needs clarification. HRV was assessed in a total of 50 participants who were asked to perform a task until becoming fatigued. Low-frequency HRV activity increased, while indices of parasympathetic modulation such as RMSSD and pNN50 remained stable as participants experienced fatigue, suggesting that fatigue in healthy individuals may be associated with increased sympathetic arousal. In addition, employing multiple regression analyses, we could positively associate the change in LF/HF HRV ratio from baseline to fatigue with factors such as emotional stability, warmth and tension and negatively associate it with social boldness and self-reported levels of vigor.

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Clinical significance of heart rate variability and Q-T interval duration during Holter monitoring of ECG in patients with essential hypertension

Arterial’naya Gipertenziya (Arterial Hypertension) ◽

10.18705/1607-419x-2004-10-1-39-42 ◽

2004 ◽

Vol 10 (1) ◽

pp. 39-42

Author(s):

A. V. Shabalin ◽

Ye. N. Gulyaeva ◽

Ye. Ye. Torochkina ◽

E. M. Verkoshanskaya ◽

O. V. Kovalenko ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Essential Hypertension ◽

Clinical Significance ◽

Comparison Group ◽

Low Frequency ◽

Holter Monitoring ◽

Total Power ◽

Interval Duration ◽

Healthy Individuals

The clinical significance of heart rate variability and Q-T interval duration during 24-hour bifunctional monitoring of ECG and blood pressure (BP) was studied in 81 patients aged 22-58 years (mean 41,40±0,72 years) who had Stages I-III essential hypertension (EH). A comparison group included 20 healthy individuals. Temporary and spectral methods were used to assess the parameters of heart rate variability; 24-hour Q-Tand O-Tk intervals, as well as echocardiographic data were analyzed. Patients with Stages I-III EH were ascertained to have a progressive decrease in diurnal heart rate variability along with a reduction in the total power of the spectrum, in the power of low-frequency constituents, and in their ratio. EH progression was found to be associated with an increase in the duration of the Q-T interval, its corrected values during daylight hours and with the degree of heart rate variability without circadian changes. The degree of autonomous cardiac control was statistically significantly related to heart rate variability and a risk for ventricular repolarization disorders.

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MRI-related anxiety in healthy individuals, intrinsic BOLD oscillations at 0.1 Hz and heart rate variability in low frequency bands

10.1101/359000 ◽

2018 ◽

Author(s):

Gert Pfurtscheller ◽

Andreas Schwerdtfeger ◽

David Fink ◽

Clemens Brunner ◽

Christoph Stefan Aigner ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Middle Cerebral Artery ◽

Frequency Band ◽

Cerebral Artery ◽

Time Delays ◽

Low Frequency ◽

Small Drop ◽

Healthy Individuals ◽

Large Drop

AbstractParticipation in a MRI scan is associated with increased anxiety, thus possibly impacting baseline recording for functional MRI studies. We investigated in 23 healthy individuals without any former MRI experience (scanner-naïve) the relations between anxiety, 0.1-Hz BOLD oscillations and heart rate variability (HRV) in two separate resting state sessions (R1, R2). BOLD signals were recorded from precentral gyrus (PCG) and insula in both hemispheres. Phase-locking and time delays were computed in the frequency band 0.07–0.13 Hz. Positive (pTD) and negative time delays (nTD) were found. The pTD characterize descending neural BOLD oscillations spreading from PCG to insula and nTD characterize ascending vascular BOLD oscillations related to blood flow in the middle cerebral artery. HRV power in two low frequency bands 0.06–0.1 Hz and 0.1–0.14 Hz was computed. Based on the drop rate of the anxiety level from R1 to R2, two groups could be identified: one with a strong anxiety decline (large drop group) and one with a moderate decline or even anxiety increase (small drop group). A significant correlation was found only between the left-hemispheric time delay (pTD, nTD) of BOLD oscillations and anxiety drop, with a dominance of nTD in the large drop group. The analysis of within-scanner HRV revealed a pronounced increase of low frequency power between both resting states, dominant in the band 0.06–0.1 Hz in the large drop group and in the band 0.1–0.14 Hz in the small drop group. These results suggest different mechanisms related to anxiety processing in healthy individuals. One mechanism (large drop group) could embrace an increase of blood circulation in the territory of the left middle cerebral artery (vascular BOLD) and another (small drop group) translates to rhythmic central commands (neural BOLD) in the frequency band 0.1–0.14 Hz.

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Heart Rate Variability, Emotions, and Music

Journal of Psychophysiology ◽

10.1027/0269-8803/a000021 ◽

2010 ◽

Vol 24 (2) ◽

pp. 112-119 ◽

Cited By ~ 9

Author(s):

F. Riganello ◽

A. Candelieri ◽

M. Quintieri ◽

G. Dolce

Keyword(s):

Data Mining ◽

Heart Rate ◽

Heart Rate Variability ◽

Vegetative State ◽

Low Frequency ◽

Emotional Reactions ◽

Heart Beat ◽

Healthy Controls ◽

Frequency Spectra ◽

Emotional Value

The purpose of the study was to identify significant changes in heart rate variability (an emerging descriptor of emotional conditions; HRV) concomitant to complex auditory stimuli with emotional value (music). In healthy controls, traumatic brain injured (TBI) patients, and subjects in the vegetative state (VS) the heart beat was continuously recorded while the subjects were passively listening to each of four music samples of different authorship. The heart rate (parametric and nonparametric) frequency spectra were computed and the spectra descriptors were processed by data-mining procedures. Data-mining sorted the nu_lf (normalized parameter unit of the spectrum low frequency range) as the significant descriptor by which the healthy controls, TBI patients, and VS subjects’ HRV responses to music could be clustered in classes matching those defined by the controls and TBI patients’ subjective reports. These findings promote the potential for HRV to reflect complex emotional stimuli and suggest that residual emotional reactions continue to occur in VS. HRV descriptors and data-mining appear applicable in brain function research in the absence of consciousness.

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Very-Low-Frequency Heart Rate Variability: Mental Stressors in Tetraplegics

PsycEXTRA Dataset ◽

10.1037/e642612010-001 ◽

2010 ◽

Author(s):

N. Lynn De Paur

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Low Frequency ◽

Very Low Frequency ◽

Mental Stressors

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Long Term Effects of Low Frequency (10 Hz) Vagus Nerve Stimulation on EEG and Heart Rate Variability in Crohn's Disease: A Case Report

Brain Stimulation ◽

10.1016/j.brs.2014.08.001 ◽

2014 ◽

Vol 7 (6) ◽

pp. 914-916 ◽

Cited By ~ 26

Author(s):

Didier Clarençon ◽

Sonia Pellissier ◽

Valérie Sinniger ◽

Astrid Kibleur ◽

Dominique Hoffman ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Crohn’S Disease ◽

Case Report ◽

Vagus Nerve ◽

Nerve Stimulation ◽

Vagus Nerve Stimulation ◽

Low Frequency ◽

Long Term Effects

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Comparing low frequency heart rate variability and preejection period: Two sides of a different coin

Psychophysiology ◽

10.1111/j.1469-8986.2008.00710.x ◽

2008 ◽

Vol 45 (6) ◽

pp. 1086-1090 ◽

Cited By ~ 35

Author(s):

Annebet D. Goedhart ◽

G. Willemsen ◽

Jan H. Houtveen ◽

Dorret I. Boomsma ◽

Eco J. C. De Geus

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Low Frequency ◽

Two Sides

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The Influence ofNrf2on Cardiac Responses to Environmental Stressors

Oxidative Medicine and Cellular Longevity ◽

10.1155/2013/901239 ◽

2013 ◽

Vol 2013 ◽

pp. 1-10 ◽

Cited By ~ 1

Author(s):

Reuben Howden ◽

Eva Gougian ◽

Marcus Lawrence ◽

Samantha Cividanes ◽

Wesley Gladwell ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

High Frequency ◽

Low Frequency ◽

Therapeutic Strategies ◽

Environmental Stressors ◽

Total Power ◽

Airborne Pollutants ◽

Cardiac Responses

Nrf2protects the lung from adverse responses to oxidants, including 100% oxygen (hyperoxia) and airborne pollutants like particulate matter (PM) exposure, but the role ofNrf2on heart rate (HR) and heart rate variability (HRV) responses is not known. We hypothesized that genetic disruption ofNrf2would exacerbate murine HR and HRV responses to severe hyperoxia or moderate PM exposures.Nrf2-/-andNrf2+/+mice were instrumented for continuous ECG recording to calculate HR and HRV (low frequency (LF), high frequency (HF), and total power (TP)). Mice were then either exposed to hyperoxia for up to 72 hrs or aspirated with ultrafine PM (UF-PM). Compared to respective controls, UF-PM induced significantly greater effects on HR (P<0.001) and HF HRV (P<0.001) inNrf2-/-mice compared toNrf2+/+mice.Nrf2-/-mice tolerated hyperoxia significantly less thanNrf2+/+mice (~22 hrs;P<0.001). Reductions in HR, LF, HF, and TP HRV were also significantly greater inNrf2-/-compared toNrf2+/+mice (P<0.01). Results demonstrate thatNrf2deletion increases susceptibility to change in HR and HRV responses to environmental stressors and suggest potential therapeutic strategies to prevent cardiovascular alterations.

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