scholarly journals SPECTROPHOTOPOLARIMETRY AS A METHOD FOR DETERMINING THE TIME DYNAMICS OF CHANGES IN THE MORPHOLOGICAL STRUCTURE OF MUSCLE TISSUE

2021 ◽  
Vol 2 ◽  
pp. 41-46
Author(s):  
Olexandr Harazdiuk ◽  
Nataliia Kozan ◽  
Viktor Kryvetskyi ◽  
Oleksandr Dunaiev
Keyword(s):  
Muscle Tissue ◽  
Temporal Dynamics ◽  
Morphological Structure ◽  
Biological Tissues ◽  
Human Muscle ◽  
Optical Parameters ◽  
Tissue Samples ◽  
Time Dynamics ◽  
Relationship Of ◽  
The Relationship

Introduction: The article presents the current state of issues regarding the diagnosis of pathological conditions for forensic medical experts, in particular the study of normal muscle tissue and in the presence of hemorrhages. Particular attention is paid to biophysical research methods with evidence-based accuracy, objectivity, reproducibility, and rapid results. Objectives: The purpose of the research was to study the possibilities of using spectrophotopolyarimetric methods to analyze and determine the relationship of morphological structure of biological tissues with the temporal dynamics of changes in their optical parameters, to establish the possibility of differentiating necrotic changes and signs of damage by applying Mueller matrices of human muscle tissue samples. Results: During the study, we found a number of features and patterns of change in the properties of the laser beam as a result of passing through biological tissue. Polarization-correlation methods provide new, objective information about the dynamics of change in laser polarimetric imaging of morphological structure of biological tissues. By analyzing the statistical distributions of the ellipticity of polarization of laser images of normal human muscle tissue and in the presence of hemorrhages, the possibility of identifying the relationship between the development of statistically significant changes with increasing time of death and the possibility of differentiating them are considered. Conclusion: Based on these results, we can conclude that employing laser polarization methods will allow us to open new doors in the study of the biological tissues of the human body. The results showed the effectiveness of the studied methodology and the prospect of further research in this direction.

Further studies on the relationship of a rhabdomyosarcoma virus to muscle tissue

1967 ◽  
Vol 2 (1) ◽  
pp. 43-51 ◽  
Author(s):  
K. Perk ◽  
J. B. Moloney ◽  
E. G. Jenkins
Keyword(s):  
Muscle Tissue ◽  
Relationship Of ◽  
The Relationship

Sample site selection for tracer studies applying a unidirectional circulatory approach

1987 ◽  
Vol 253 (2) ◽  
pp. E173-E178 ◽  
Author(s):  
D. K. Layman ◽  
R. R. Wolfe
Keyword(s):  
Specific Activity ◽  
Sampling Site ◽  
Vena Cava ◽  
Gas Chromatography Mass Spectrometry ◽  
Tracer Studies ◽  
Tissue Samples ◽  
Circulatory Model ◽  
Plasma Leucine ◽  
Relationship Of ◽  
The Relationship

The optimal arterial or venous sites for infusion and sampling during isotopic tracer studies have not been established. This study determined the relationship of plasma and tissue enrichment (E) when isotopes were infused in an artery and sampled from a vein (av mode) or infused in a vein and sampled from an artery (va mode). Adult dogs were given primed constant infusions of [3-13C]lactate, [1-13C]leucine, and 14C-labeled bicarbonate. Simultaneous samples were drawn from the vena cava, aortic arch, and breath. Tissue samples were removed from skeletal muscle, liver, kidney, and gut. Breath samples were analyzed for 14CO2 by liquid scintillation counting and plasma isotopic enrichments of [13C]lactate, [13C]leucine, and alpha-[13C]ketoisocaproate (KIC) were determined by gas chromatography-mass spectrometry. By using the va mode, the plasma E for lactate and leucine were 30-40% above tissue E. The av mode provided an accurate reflection of tissue E for lactate, which equilibrates rapidly with tissues, and a reasonable estimate for leucine, which exchanges more slowly. The isotopic enrichment of plasma KIC more directly reflected tissue leucine E than did plasma leucine E, and KIC enrichment was insensitive to sampling site. We also evaluated theoretically a circulatory model that predicts venous isotopic enrichments when the va mode is used. We conclude that the av mode is optimal but that the problems arising from use of the va mode can be overcome by use of a metabolic product (i.e., KIC) or by calculation of venous specific activity with our circulatory mode.

scholarly journals Relationship of the BOLD Signal with VEP for Ultrashort Duration Visual Stimuli (0.1 to 5 ms) in Humans

2009 ◽  
Vol 30 (2) ◽  
pp. 449-458 ◽  
Author(s):  
Barış Yeşilyurt ◽  
Kevin Whittingstall ◽  
Kâmil Uğurbil ◽  
Nikos K Logothetis ◽  
Kâmil Uludağ
Keyword(s):  
Brain Function ◽  
Temporal Dynamics ◽  
Visual Stimulation ◽  
Impulse Response Function ◽  
Blood Oxygenation ◽  
Context Dependency ◽  
Oxygenation Level ◽  
Relationship Of ◽  
The Relationship ◽  
The Brain

There is currently a great interest to combine electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) to study brain function. Earlier studies have shown different EEG components to correlate well with the fMRI signal arguing for a complex relationship between both measurements. In this study, using separate EEG and fMRI measurements, we show that (1) 0.1 ms visual stimulation evokes detectable hemodynamic and visual-evoked potential (VEP) responses, (2) the negative VEP deflection at ∼80 ms (N2) co-varies with stimulus duration/intensity such as with blood oxygenation level-dependent (BOLD) response; the positive deflection at ∼120 ms (P2) does not, and (3) although the N2 VEP–BOLD relationship is approximately linear, deviation is evident at the limit of zero N2 VEP. The latter finding argues that, although EEG and fMRI measurements can co-vary, they reflect partially independent processes in the brain tissue. Finally, it is shown that the stimulus-induced impulse response function (IRF) at 0.1 ms and the intrinsic IRF during rest have different temporal dynamics, possibly due to predominance of neuromodulation during rest as compared with neurotransmission during stimulation. These results extend earlier findings regarding VEP–BOLD coupling and highlight the component- and context-dependency of the relationship between evoked potentials and hemodynamic responses.

scholarly journals Tryptophan metabolic profile in term and preterm breast milk: implications for health

2018 ◽  
Vol 7 ◽  
Author(s):  
Louise O'Rourke ◽  
Gerard Clarke ◽  
Aoife Nolan ◽  
Claire Watkins ◽  
Timothy G. Dinan ◽  
...  
Keyword(s):  
Breast Milk ◽  
Temporal Dynamics ◽  
Maternity Hospital ◽  
Meso Scale Discovery ◽  
Tnf Α ◽  
Expressed Breast Milk ◽  
Infant Neurodevelopment ◽  
Relationship Of ◽  
The Relationship ◽  
Breast Fed

AbstractBreast milk is the only source of the essential amino acid tryptophan (TRP) in breast-fed infants. Low levels of TRP could have implications for infant neurodevelopment. The objectives of the present study were to compare the relationship of TRP and its neuroactive pathway metabolites kynurenine (Kyn) and kynurenic acid (KynA) in preterm and term expressed breast milk (EBM) in the first 14 d following birth, and the relationship of TRP metabolism to maternal stress and immune status. A total of twenty-four mothers were recruited from Cork University Maternity Hospital: twelve term (>38 weeks) and twelve preterm (<35 weeks). EBM samples were collected on days 7 and 14. Free TRP, Kyn and KynA were measured using HPLC, total TRP using MS, cytokines using the Meso Scale Discovery (MSD) assay system, and cortisol using a cortisol ELISA kit. Although total TRP was higher in preterm EBM in comparison with term EBM (P< 0·05), free TRP levels were lower (P< 0·05). Kyn, KynA and the Kyn:TRP ratio increased significantly in term EBM from day 7 to day 14 (P< 0·05), but not in preterm EBM. TNF-α, IL-6 and IL-8 were higher in day 7 preterm and term EBM in comparison with day 14. There were no significant differences between term and preterm EBM cortisol levels. Increased availability of total TRP, lower levels of free TRP and alterations in the temporal dynamics of TRP metabolism in preterm compared with term EBM, coupled with higher EBM inflammatory markers on day 7, may have implications for the neurological development of exclusively breast-fed preterm infants.

Relationship of Salt Disparity and Its Consequence for Swelling in Biological Gels

1995 ◽  
Vol 48 (10) ◽  
pp. 681-683
Author(s):  
Stuart Hodson ◽  
Richard Earlam
Keyword(s):  
Thermodynamic Property ◽  
Fluid Flows ◽  
Biological Tissues ◽  
Irreversible Thermodynamic ◽  
Thermodynamic Relationships ◽  
Relationship Of ◽  
The Relationship ◽  
Osmotic Potentials

New irreversible thermodynamic relationships are derived which explain why biological tissues tend to swell. In the course of their derivation, fresh concepts arize. In particular, the relationship of salt disparity is described which forbids diffusible salt generated chemical and osmotic potentials to be simultaneously at equilibrium in the presence of ionized macromolecules. This relationship is developed to generate a new intrinsic thermodynamic property which is termed gel pressure and which drives fluid flows.

Effect of Process Variables and Dopants on Characteristics of Electrochemically-Deposited Pedot Films

2002 ◽  
Vol 736 ◽  
Author(s):  
Mihir A. Oka ◽  
Stephen S. Hardaker ◽  
Farzad Nazir ◽  
Richard V. Gregory ◽  
Keith R. Brenneman ◽  
...  
Keyword(s):  
Electrode Materials ◽  
Morphological Structure ◽  
Constant Current ◽  
Process Variables ◽  
Residual Solvent ◽  
Force Microscopy ◽  
Atomic Force ◽  
Electrochemically Deposited ◽  
Relationship Of ◽  
The Relationship

ABSTRACTPoly(3,4-ethlyenedioxythiophene), PEDOT, has found wide use in applications such as electrostatic coatings, antistatic layers and electrode materials in electronic devices. Electrochemical deposition of PEDOT is a prominent means of obtaining thin, uniform films. However, the relationship of these films' properties to their morphological structure is still poorly understood. We have prepared PEDOT films by electrochemical oxidation of monomer (3,4-ethylenedioxythiophene), EDOT, under constant current conditions, employing a variety of electrolytes, and processing conditions. We report the effect of using different dopants, deposition time, deposition temperature and current density on the observed conductivity of PEDOT films. Atomic force microscopy studies were carried out to determine the possible effect of the process variables on the resulting film morphology. Also, the effect of residual solvent on the conductivity of the films was studied by thermogravimetric analysis (TGA).

scholarly journals Study of psychological time dynamics at the age of youth

2020 ◽  
Vol 17 (4) ◽  
pp. 75-90
Author(s):  
Valentina I. Volokhova ◽  
Marina I. Koshenova ◽  
Denis M. Shabanov
Keyword(s):  
Pilot Study ◽  
Time Perspective ◽  
Identity Status ◽  
Time Dynamics ◽  
The Past ◽  
Current Trends ◽  
The Status ◽  
Relationship Of ◽  
The Relationship

This paper presents the current trends analysis of research into the psychological time of personality in foreign and domestic psychology, justified the need to study the dynamics of psychological time at the period of youth at conditional points of bifurcation associated with the forced need to make personal choices: in early and late youth. The reasonability of investigating the relationship of psychological time with personal identity as a predictor of self-realisation or maladaptation of personality at the stage of youth is shown. The pilot study presented in this work is aimed at identifying differences in the content characteristics and structure of psychological time in early and late youth. The ascertaining experiment was conducted with two groups (the total number of participants is 50 people). Diagnostic toolkit: the technique of F. Zimbardo on the time perspective (ZTPI), adapted by A. Syrtsova, the technique Time Experience Scale by E.I. Golovakhi, A.A. Kronik, as well as the technique Identity Status according to Marcia in the modification of the questionnaire G. and R. Aminev. Methods of mathematical statistics: t-Students criterion for independent samples and Pearsons index of linear correlation. The data obtained in the pilot study made it possible to draw conclusions that 1) the meaningful characteristics of psychological time in different periods of youth are not identical, 2) the characteristics of psychological time significantly correlate with the status of personality identity, and such a relationship is more important precisely in the period of early adolescence. The obtained data provided an opportunity to clarify the further direction of research and to outline the necessary ways of psychological support of the person during his youth in the conditions of modern social reality. For the prevention of maladaptation and destructive realization of the personality in the period of youth, targeted work is proposed with the psychological time of the personality, with the adoption of the past and the planning of the future, the determination of priorities, goal setting and the formation of temporal competence.

scholarly journals Spatio-temporal dynamics of the penetration resistance of recultivated soils formed after open cast mining

2016 ◽  
Vol 24 (2) ◽  
Author(s):  
A. V. Zhukov ◽  
G. А. Zadorozhnaya
Keyword(s):  
Spatial Dependence ◽  
Temporal Dynamics ◽  
Morphological Structure ◽  
Soil Formation ◽  
Penetration Resistance ◽  
Time Dynamics ◽  
Open Cast Mining ◽  
Soil Penetration Resistance ◽  
Soil Structures ◽  
Spatio Temporal

On the basis of studying the spatio-temporal dynamics of soil penetration resistance we proved the existence of the technozem ecomorphs as above horizon soil formations. Research was carried out at a research center for study of recultivation processes in Ordzhonikidze city. Measurement of soils penetration was made in field conditions using an Eijkelkamp penetrometer on a regular grid at depths of up to50 cmwith intervals of5 cm. Calculation of average values and degrees of variation was performed by means of descriptive statistical tools. The extent of soil penetration spatial dependence was assessed and the existence of ecomorphs was proved by means of geostatistical analysis. The degree of associativity of spatial distribution of indicators of a soil body in different years of research was established by means of correlation analysis. The level of variation in space and in time of  technozem penetration generated on loess-like loams, grey-green, red-brown clays, and also pedozems was revealed. The degree of spatial dependence of  technozem penetration within soil layers and also the linear sizes of ecomorphs as above horizon soil structures was established. The time dynamics of  penetration of various recultozems were described. As a result of research into the spatio-temporal dynamics of penetration of technozems, data confirming the hypothesis of the existence of ecomorphs as above horizon morphological soil formations were obtained. An ecomorphic approach to the study of the morphological structure of technozems is proposed. The comparative characteristics of ecomorphs from various types of technozem are presented. The results obtained solve the problem of combining the higher and lowest levels in the hierarchical system of soil organisation as a natural body, which should raise the efficiency of the analysis of relations of morphological elements as a basis for detailed reconstruction of recultivation processes, soil formation, and study of their regimes and functions.

scholarly journals Study of the relationship of cavitation erosion activity and cavitation noise intensity

Doklady BGUIR ◽  
2020 ◽  
Vol 18 (8) ◽  
pp. 97-103
Author(s):  
V. S. Minchuk ◽  
A. Yu. Perkhunova ◽  
A. V. Kotukhov ◽  
N. V. Dezhkunov
Keyword(s):  
Output Signal ◽  
Cavitation Erosion ◽  
Integral Intensity ◽  
Biological Tissues ◽  
Cavitation Noise ◽  
Cavitation Region ◽  
Improved Technique ◽  
Relationship Of ◽  
The Relationship

The study of the erosion activity of cavitation is of considerable interest for clarifying the mechanism of the effect of cavitation on biological tissues and cells. This paper proposes an improved technique for assessing the erosion activity of acoustic cavitation. The results of testing this technique in relation to the problem of studying the distribution of erosion activity in the cavitation region, generated by a radiator with a rod waveguide, are presented. The experiments were carried out using a submersible emitter with a resonant frequency of 32 kHz. It was found that erosion activity rapidly decreases with distance from the emitter and depends on the distance to the emitter L as 1/L3 when the diameter of the emitter is less than or of the order of the wavelength in the used liquid. It was shown that there is a correlation between the erosion activity of cavitation and the readings of the cavitometer with the output signal being the integral intensity of the highfrequency component of the cavitation noise in the frequency range up to 10 MHz. Piezoelectric sensors were used to register cavitation noise. In particular, in liquids characterized by a higher level of erosion activity, the output signal of the cavitometer is also higher. In this case, the readings of the cavitometer change depending on the distance to the radiator as 1/L. Based on the data obtained, a method is proposed for assessing the erosion activity of cavitation by the magnitude of the intensity of cavitation noise in a cube. It is shown that this parameter is linearly related to the results of measurements of the erosional activity of cavitation. The results obtained will be used in the development of a specialized cavitometer designed to assess the erosion activity of cavitation during in vitro studies of the effect of ultrasound on cells.

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