scholarly journals The Relationship of Executive Function and Sentence Comprehension Ability in Children with High-Function Autism

2013 ◽  
Vol 18 (3) ◽  
pp. 297-310
Author(s):  
A Ra Kho ◽  
Dongsun Yim
Author(s):  
Elisabeth Kliem ◽  
Elise Gjestad ◽  
Truls Ryum ◽  
Alexander Olsen ◽  
Bente Thommessen ◽  
...  

Abstract Objective: Findings on the relationship of psychiatric symptoms with performance-based and self-reported cognitive function post-stroke are inconclusive. We aimed to (1) study the relation of depression and anxiety to performance-based cognitive function and (2) explore a broader spectrum of psychiatric symptoms and their association with performance-based versus self-reported cognitive function. Method: Individuals with supratentorial ischemic stroke performed neuropsychological examination 3 months after stroke. For primary analyses, composite scores for memory and attention/executive function were calculated based on selected neuropsychological tests, and the Hospital Anxiety and Depression Scale (HADS) was used. Psychiatric symptoms and self-reported cognitive function for secondary aims were assessed using the Symptom-Checklist-90 – Revised (SCL-90-R). Results: In a sample of 86 patients [mean (M) age: 64.6 ± 9.2; Mini-Mental State Examination (MMSE), 3–7 days post-stroke: M = 28.4 ± 1.7; National Institutes of Health Stroke Scale (NIHSS) after 3 months: M = 0.7 ± 1.6] depressive symptoms (HADS) were associated with poorer memory performance after controlling for age, sex, and education (p ≤ .01). In a subsample (n = 41; Age: M = 65.7 ± 8.1; MMSE: M = 28.4 ± 1.8; NIHSS: M = 1.0 ± 1.9), symptoms of phobic anxiety (SCL-90-R) were associated with poorer performance-based memory and attention/executive function, and symptoms of anxiety (SCL-90-R) with lower attention/executive function. Higher levels of self-reported cognitive difficulties were associated with higher scores in all psychiatric domains (p ≤ .05). Conclusion: Even in relatively well-functioning stroke patients, depressive symptoms are associated with poorer memory. The results also suggest that various psychiatric symptoms are more related to self-reported rather than to performance-based cognitive function. Screening for self-reported cognitive difficulties may not only help to identify patients with cognitive impairment, but also those who need psychological treatment.


2020 ◽  
Vol 375 (1811) ◽  
pp. 20190618 ◽  
Author(s):  
Agnès Lacreuse ◽  
Naftali Raz ◽  
Daniel Schmidtke ◽  
William D. Hopkins ◽  
James G. Herndon

Executive function (EF) is a complex construct that reflects multiple higher-order cognitive processes such as planning, updating, inhibiting and set-shifting. Decline in these functions is a hallmark of cognitive ageing in humans, and age differences and changes in EF correlate with age-related differences and changes in association cortices, particularly the prefrontal areas. Here, we review evidence for age-related decline in EF and associated neurobiological changes in prosimians, New World and Old World monkeys, apes and humans. While EF declines with age in all primate species studied, the relationship of this decline with age-related alterations in the prefrontal cortex remains unclear, owing to the scarcity of neurobiological studies focusing on the ageing brain in most primate species. In addition, the influence of sex, vascular and metabolic risk, and hormonal status has rarely been considered. We outline several methodological limitations and challenges with the goal of producing a comprehensive integration of cognitive and neurobiological data across species and elucidating how ageing shapes neurocognitive trajectories in primates with different life histories, lifespans and brain architectures. Such comparative investigations are critical for fostering translational research and understanding healthy and pathological ageing in our own species. This article is part of the theme issue ‘Evolution of the primate ageing process’.


Aphasiology ◽  
2011 ◽  
Vol 25 (6-7) ◽  
pp. 826-835 ◽  
Author(s):  
Jennifer Mozeiko ◽  
Karen Le ◽  
Carl Coelho ◽  
Frank Krueger ◽  
Jordan Grafman

2020 ◽  
Vol 77 (6) ◽  
pp. 620-630
Author(s):  
Mirjana Djordjevic ◽  
Nenad Glumbic ◽  
Branislav Brojcin

Background/Aim. The ability to comprehend and produce irony and deception is rarely explored in people with intellectual disability (ID) or dual diagnoses (DD). The ability to understand irony and deception appears to be related to many cognitive skills, but some authors point out that the theory of mind is one of the most important factors for this ability. This research was conducted to determine the linguistic aspects of production and comprehension of irony and deception in adults with ID and DD, as well as the relationship of these abilities with theory of mind. Methods. The sample consisted of 120 people with ID aged between 20 and 56. Half of the sample comprised people with DD. Four subscales from the Assessment Battery for Communication were used to assess the participants? abilities to produce and comprehend irony and deception. False-belief tasks from ?appearance-reality? category were used in theory of mind assessment. The level of intellectual functioning was measured by the Raven?s progressive matrices, while the Peabody Picture Vocabulary Test was used to assess speech comprehension ability. Results. The results show that participants with DD and ID comprehend and produce false statements better than ironic ones. Participants with ID were more successful in production than in comprehension tasks of both false and ironic statements, while the same was true for participants with DD only for ironic statements. Participants with ID were significantly more successful than participants with DD in irony comprehension tasks. In participants with ID, first-order theory of mind significantly correlated only with the ability to produce irony, and second-order theory of mind significantly correlated with producing irony and deception. There were no significant correlations between theory of mind and producing and comprehending irony and deception in participants with DD. Conclusion. Although differences in some aspects of assessed abilities were found between the two groups of participants, the similarities in the profile of these abilities were dominant. Results of variability can be explained by differences in speech comprehension ability more than by differences in nonverbal intellectual functioning or theory of mind acquisition. Future studies should assess the influence of other cognitive factors.


Sign in / Sign up

Export Citation Format

Share Document