Solving the mysteries of narcolepsy

2020 ◽  
Vol 16 (6) ◽  
pp. 252-253
Author(s):  
Mark Greener
Keyword(s):  
Quality Of Life ◽  
Social Life ◽  
Mental Wellbeing ◽  
The Impact ◽  
Life Work

Narcolepsy can profoundly affect a patient's quality of life, including their mental wellbeing, social life, work and study. Mark Greener briefly summarises some recent papers that offer new insights into the causes of narcolepsy, the overlap with depression and other comorbidities, and the impact on patients.

scholarly journals The impact of pregnancy on women’s oral health-related quality of life: a qualitative investigation

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Omid Fakheran ◽  
Mahmoud Keyvanara ◽  
Zahra Saied-Moallemi ◽  
Abbasali Khademi
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Pregnant Women ◽  
Social Life ◽  
Well Being ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Abstract Background Complex psychological and physiological changes occur in women’s body during pregnancy. These changes affect both oral health status and oral health-related quality of life (OHRQoL). In almost all of the previous cross-sectional design studies on pregnant women, generic OHRQoL instruments have been used to measure OHRQoL. While such instruments may be reliable, they may not be appropriate to evaluate the OHRQoL in special populations like pregnant women. The purpose of this study was to investigate the self-perceived factors affecting the OHRQoL among pregnant women. Methods In this qualitative descriptive study, twenty- seven pregnant women were recruited from four healthcare centers located in Isfahan city, Iran. The interpretative phenomenological analysis was used to collect and analyze the data. Four criteria of credibility, dependability, transferability, and confirmability were implemented through established procedures to confirm the study rigor. Results Three major themes and six sub-themes capturing the impacts of pregnancy on women’s OHRQoL were identified. They covered all areas of life, including daily life, psychological well-being, social life, physical impact, and also barriers to utilization of dental care services. Some new domains such as “dentists’ refusal to treat pregnant women”, “negative feelings about pregnancy” and “concerns about fetal health” were found as important factors which could influence the OHRQoL during pregnancy. Conclusion The findings help to better understand the oral health issues impacting women during pregnancy and to achieve person-centered care and improved oral health outcomes in pregnant women. The conceptual framework created based on the results of this study may help health care workers and policy makers for improving the health of pregnant women.

scholarly journals Impact of Mental wellbeing and Quality of Life on Depression, Anxiety and Stress among people living with HIV/AIDS (PLWHA)

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Bhavna Mukund ◽  
Rejani Thudalikunil Gopalan
Keyword(s):  
Quality Of Life ◽  
Well Being ◽  
Mental Wellbeing ◽  
People Living With Hiv ◽  
Depression And Anxiety ◽  
Living With Hiv ◽  
The Impact ◽  
Mental Well Being ◽  
Hiv Aids

Background: People living with HIV/AIDS (PLWHA) manifest a wide range of stress responses ranging from disbelief, denial, fear to extreme conditions of anxiety disorders, depression and even suicidal thoughts. These complications can have a significant impact on daily functioning and greatly diminish quality of life. Mental wellbeing and Quality of Life can help in better management of stress and facilitate adaptive coping among PLWHA. Aim: The research examined the impact of mental wellbeing and Quality of Life on Depression, Anxiety and Stress among people living with HIV/AIDS infection. Research Design: Cross sectional survey design was used. Sample: A sample of 60 people (males and females of equal number) over the age of 18 years and with the diagnosis for HIV/AIDS for more than six months participated in the study. Tools used: To assess the depression, anxiety and stress among PLWHA, DASS scale was used and to assess their psychological wellbeing, Warwick Edinburgh Mental Well-Being scale was used. In order to assess their present status of QOL regarding the illness, WHO’s QOL HIV-BREF Scale was used. Results: Majority of the PLWHA had moderate level of anxiety and mild level of depression after being diagnosed. Most of the participants have positive mental well-being and had enhanced quality of life. Conclusion: A direct effect of mental wellbeing has been found on the depression, anxiety and stress among PLWHA indicating that higher the mental wellbeing of the PLWHA, the greater is the likelihood that they do not suffer from depression, exhibit less anxiety and are living a stress free life and vice versa. The study also found direct impact of QOL on psychological distress, depression and anxiety among PLWHA i.e. poor QOL of PLWHA makes them more prone to and vulnerable to stress, depression and anxiety and vice versa.

scholarly journals The Impact of the Brexit on the Living Standards and Quality of Life in Britain

2020 ◽  
Vol 16 (2) ◽  
pp. 51-60
Author(s):  
Yefim S. Khesin
Keyword(s):  
Quality Of Life ◽  
European Union ◽  
Great Britain ◽  
Social Life ◽  
Transition Period ◽  
Well Being ◽  
Living Standards ◽  
The Uk ◽  
The Impact

The Object of the Study. Living standards and quality of life of the population in Great Britain. The Subject of the Study. The Brexit. The Purpose of the Study is exposing the impact of the Brexit on the living standards and quality of life in the country. The Main Provisions of the Article. Following a June 2016 referendum on continued European Union membership in which 52% voted to leave and 48% voted to stay the UK government announced the country's withdrawal from the EC (Brexit). In March 2017 it formally began the withdrawal process. The withdrawal was delayed by deadlock in the UK parliament. Having failed to get her agreement with the EC approved, Theresa May resigned as Prime Minister in July 2019 and was succeeded by Boris Johnson, an active supporter of the Brexit. An early general election was then held on 12 December. The Conservatives won a large majority. As a result, the parliament ratified the withdrawal agreement, and the UK formally left the EU on 31 January 2020. This began a transition period that is set to end on 31 December 2020, during which the UK and EU will negotiate their future relationship. The first round of negotiations between London and Brussels began in March 2020. The author investigates the consequences of the withdrawal of Great Britain from the EC on the living standards and quality of life, economic situation, labour market, social policy of the government. in this country. It analyzes on the impact of the Brexit on the major elements of human capital: education, science, health, living conditions, ecology. It found that short-term forecasts of what would happen immediately after the Brexit referendum were too pessimistic. Nowadays it is very difficult to give an accurate estimate of the future effect of the Brexit on cost of living in Great Britain – many essential issues in the relations between the UK and the EC remain open. Besides, the coronavirus crisis and lockdown measures may cause the grave damage to growth and jobs. Much evidence shows that in the medium- and long-term leaving the European Union damage the British economy and thus reduce the UK's real per-capita income level and may adversely affect jobs and earnings, income and wealth, life expectancy, education and skills, academic research, health status, environmental quality and subjective well-being in the UK. Finally, the author analyses the impact on the economic and social life in Great Britain of different Brexit scenarios after the end of the transition period. The consequences will differ sharply depending on whether the UK does a Soft or Hard (no deal) Brexit.

scholarly journals ACUTE MYOCARDIAL INFARCTION;

2019 ◽  
Vol 26 (01) ◽  
Author(s):  
Shakeel Ahmad ◽  
Muhammad Nazim ◽  
Rizwan Munir ◽  
Hafiz Muhammad Faiq Ilyas ◽  
Naeem Asghar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Sample Size ◽  
Social Life ◽  
Sleep Disturbances ◽  
Sampling Technique ◽  
Study Results ◽  
The Impact

Objectives: To assess the impact of myocardial infarction on quality of life in four year survivors and to determine factors associated with a poor quality of life. Design: Descriptive study. Settings: Faisalabad institute of cardiology Faisalabad. Duration of Study: 1st November 2017 to 30 April 2018. Sample Size: Sample size was 200 as calculated by WHO sample size calculator. Sampling Technique: Non probability consecutive sampling. Subjects: All patients diagnosed with acute myocardial infarction during 2013 and alive at a median of four years. Patients and Methods: 200 patients presenting in outdoor for routine follow up checkup who got MI approximately four years ago in year 2013 were included in the study. Results: 200 patients with an acute myocardial infarction in 2013 and alive and capable of responding to a questionnaire in 2018 were included in the study. Physical functioning was normal in 63%, fair in 25% and disturbed in 12% of patients. Social life functioning was normal in 66%, fair in 26% and disturbed in 8% of patients. No Angina episodes in 61.5%, 1 to 2 angina episodes per month in 25% and more than 3 episodes per month in 13.5% patients. 59% of patients were doing routine jobs, 21.5 % were doing off and on job and 19.5% were not doing any job after MI. Conclusions: this study provides valuable information for the practicing clinicians. Impaired quality of life was reported by patients, unfit for work, those with angina and dyspnea, patients with coexistent lung disease, those with anxiety and sleep disturbances and other co-morbid conditions. Improving quality of life after MI remains a challenge for practicing physicians.

scholarly journals ‘Never again will I be carefree’: a qualitative study of the impact of hypoglycemia on quality of life among adults with type 1 diabetes

2021 ◽  
Vol 9 (1) ◽  
pp. e002322
Author(s):  
Hannah Chatwin ◽  
Melanie Broadley ◽  
Mette Valdersdorf Jensen ◽  
Christel Hendrieckx ◽  
Jill Carlton ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 1 Diabetes ◽  
Social Life ◽  
Limited Participation ◽  
Personal Impact ◽  
Fear Of Hypoglycemia ◽  
The Uk ◽  
The Impact

IntroductionAchieving glycemic targets and optimizing quality of life (QoL) are important goals of type 1 diabetes care. Hypoglycemia is a common barrier to achieving targets and can be associated with significant distress. However, the impact of hypoglycemia on QoL is not fully understood. The aim of this study was to explore how adults with type 1 diabetes are impacted by hypoglycemia in areas of life that are important to their overall QoL.Research design and methodsParticipants responded to a web-based qualitative survey involving a novel ‘Wheel of Life’ activity. Responses were analyzed using reflexive thematic analysis.ResultsThe final sample included 219 adults with type 1 diabetes from Denmark, Germany, the Netherlands, and the UK. They had a mean±SD age of 39±13 years and diabetes duration of 20±14 years. Participants identified eight areas of life important to their overall QoL, including relationships and social life, work and studies, leisure and physical activity, everyday life, sleep, sex life, physical health, and mental health. Participants reported emotional, behavioral, cognitive, and social impacts of hypoglycemia within domains. Across domains, participants described interruptions, limited participation in activities, exhaustion, fear of hypoglycemia, compensatory strategies to prevent hypoglycemia, and reduced spontaneity.ConclusionsThe findings emphasize the profound impact of hypoglycemia on QoL and diabetes self-care behaviors. Diabetes services should be aware of and address the burden of hypoglycemia to provide person-centered care. Clinicians could ask individuals how hypoglycemia affects important areas of their lives to better understand the personal impact and develop tailored management plans.

scholarly journals ASSESSMENT OF PSYCHO-SOCIAL IMPACT OF ACNE AMONG YOUNG ADULTS - A CROSS SECTIONAL STUDY AT A TERTIARY CARE HOSPITAL OF RAWALPINDI

2021 ◽  
Vol 71 (4) ◽  
pp. 1171-74
Author(s):  
Zubaida Rashid ◽  
Syed Fawad Mashhadi ◽  
Imtenan Sharif ◽  
Syeda Urooj Zaidi ◽  
Saira Maroof ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Social Life ◽  
Well Being ◽  
Strong Positive Correlation ◽  
Care Hospital ◽  
Self Perception ◽  
Cross Sectional ◽  
The Impact

Objective: To assess the psychosocial impact of acne and to evaluate the quality of life in relation to severity of symptoms among young adults. Study Design: Cross-sectional – analytical study. Place and Duration of Study: Outpatient Department, Pak Emirates Military Hospital, Rawalpindi, from Sep 2018 to Feb 2019. Methodology: We included 300 individuals visiting the hospital and their quality of life was assessed using Acne quality of life Index questionnaire. Data was analyzed using SPSS-23. Results: Total scores were calculated for three domains of Quality of life in patients with Acne i.e. Self-perception, Emotional well-being and Social life. Out of these three domains, Social Life was most affected by acne (mean score 15.61 ± 7.37out of a total of 30) and Self-Perception was seen to be least affected (mean score 16.90 ± 8.20). There was a strong positive co-relation between the increasing severity of symptoms and impact on Self Perception (r=-0.58, p<0.01), between severity and Impact on Social life (r=-0.581, p<0.01) and between severity of symptoms and Impact on emotional well-being of the patients (r=-0.551, p<0.01). A significant difference was seen between the two genders with reference to the impact on “Social Life”, the meanscore for Males being 13.96 ± 7.55 while that for Females being 17.29 ± 6.81 (p<0.01). Conclusion: Acne has significant impact on the quality of life of patients treated by primary care physicians. The severity of symptoms had strong positive correlation with self-perception, social and emotional domains.

Development of a functional assessment of side-effects to therapy (FAST) questionnaire to assess dermatology-related quality of life in patients treated with EGFR inhibitors (EGFRI): The FAST-EGFRI

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 19532-19532 ◽  
Author(s):  
L. Wagner ◽  
S. E. Lai ◽  
M. Aneja ◽  
P. Lorusso ◽  
R. Perez-Soler ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Social Life ◽  
Symptom Burden ◽  
Physical Symptoms ◽  
Self Report ◽  
Antitumor Effects ◽  
Related Quality ◽  
The Impact ◽  
Skin Pain

19532 Background: Despite their beneficial antitumor effects, 75–87% patients who undergo EGFRI therapy develop dermatological toxicities (derm tox), including rash, paronychia, hair alterations, and pruritus. The purpose of this study was to develop a patient (pts) self-report questionnaire based on pts and expert (exp) input and to identify the most significant skin tox health-related quality of life (HRQL) factors. Methods: To generate the questionnaire, 20 pts with derm tox to EGFRIs and 12 expert clinicians (>50 treated pts) were asked interview questions and rated 62 items to assess the most bothersome aspects of derm tox and the impact on pts’ skin-specific HRQL. The questionnaire included items from the Skindex-29, a validated skin disease-specific HRQL questionnaire. Items were rated from 0 (not at all important) to 3 (extremely important) (range = 0–3) based on the items’ significance to patients’ HRQL. Both groups were also asked to circle 20 of the most concerning HRQL factors. Results: Eighteen pts and 11 exp completed the questionnaire. Symptoms reported frequently by both pts and exp that affected patients’ HRQL included painful (mean score 2.29 (pts), 2.70, (exp), burning (2.41 (pts), 2.70 (exp)), itchy (2.00 (pts), 2.20 (exp) skin, pain in fingers/toes (2.00 (pts), 2.40 (exp)) increased facial hair (1.93(pts), 1.70 (exp)). Both pts and exp also frequently reported that the patient’s skin condition makes them feel depressed (1.88 (pts), 2.60 (exp)) and makes work or hobbies difficult (2.00 (pts), 2.20 (exp)). The top three most concerning HRQL factors for pts were skin pain, burning and stinging, and irritation, while exp reported depression, skin pain, and derm tox affecting pts’ social life. Conclusions: These results document the trajectory of symptom burden and derm tox HRQL in EGFRI treated pts. These findings underscore that in addition to the psychosocial discomfort, physical symptoms impact HRQL. Further studies to validate the FAST-EGFRI, so that effects on HRQL of interventions against derm tox and differences between agents can be assessed are underway. No significant financial relationships to disclose.

Conventional versus atypical neuroleptics: subjective quality of life in schizophrenic patients

1997 ◽  
Vol 170 (5) ◽  
pp. 422-425 ◽  
Author(s):  
M. Franz ◽  
Stefanie Lis ◽  
K. Plüddemann ◽  
B. Gallhofer
Keyword(s):  
Quality Of Life ◽  
Social Life ◽  
Well Being ◽  
Subjective Quality ◽  
Psychotic Symptoms ◽  
Atypical Neuroleptics ◽  
Subjective Quality Of Life ◽  
Schizophrenic Patients ◽  
The Impact

BackgroundThe effectiveness of anti-psychotic drugs against positive psychotic symptoms has been demonstrated in many studies, but their effects on quality of life have yet to be clarified. The impact of different neuroleptic therapies on the subjective quality of life of schizophrenic patients is evaluated in a cross-sectional open study.MethodDuring a four-month period a standardised quality of life interview for schizophrenic patients was applied on day 10 after admission; 33 patients on atypical neuroleptics (AAP) were compared with 31 matched patients on conventional neuroleptics (CAP).ResultsThe AAP group had significantly higher scores in general quality of life as well as in different life domains: physical well-being, social life and everyday life. In separate comparisons of the AAP group, patients on clozapine and risperidone were found to have a higher quality of life score than patients on CAP or zotepine.ConclusionsThe pharmacological profile of clozapine and risperidone may provide a basis for explaining the higher subjective quality of life found in this study. The lower quality of life of the CAP group may possibly be related to intrinsic effects of the conventional antipsychotics.

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