scholarly journals At-Large Workgroup: Themes and Observations

2016 ◽  
Vol 1 ◽  
Author(s):  
Ali Andalibi ◽  
Todd Carpenter ◽  
Nina K. Collins ◽  
Joann C. Delenick ◽  
Sindy Escobar-Alvarez ◽  
...  

The At-Large group was the largest and most diverse in terms of stakeholder representation. At-large delegates observed workgroup conversations during the meeting and contributed to these conversations while letting the workgroup teams answer their questions. At-large delegates met during the conference and convened online both before and after the conference in order to develop some high level takeaways based on what they observed. While workgroups focused on answering a particular big question confronting scholarly publishing, at-large delegates had a wide-angle lens on the evolution of these questions and proceedings.


1987 ◽  
Vol 32 (1) ◽  
pp. 54-55
Author(s):  
Jack P. Shonkoff


2021 ◽  
Vol 12 ◽  
pp. 204062232110052
Author(s):  
Jeremy Chambord ◽  
Lionel Couzi ◽  
Pierre Merville ◽  
Karine Moreau ◽  
Fabien Xuereb ◽  
...  

Aims: To assess the effect of a pharmacist-led intervention, using Barrows cards method, during the first year after renal transplantation, on patient knowledge about their treatment, medication adherence and exposure to treatment in a French cohort. Methods: We conducted a before-and-after comparative study between two groups of patients: those who benefited from a complementary pharmacist-led intervention [intervention group (IG), n = 44] versus those who did not [control group (CG), n = 48]. The pharmacist-led intervention consisted of a behavioral and educational interview at the first visit (visit 1). The intervention was assessed 4 months later at the second visit (visit 2), using the following endpoints: treatment knowledge, medication adherence [proportion of days covered (PDC) by immunosuppressive therapy] and tacrolimus exposure. Results: At visit 2, IG patients achieved a significantly higher knowledge score than CG patients (83.3% versus 72.2%, p = 0.001). We did not find any differences in treatment exposure or medication adherence; however, the intervention tended to reduce the proportion of non-adherent patients with low knowledge scores. Using the PDC by immunosuppressive therapy, we identified 10 non-adherent patients (10.9%) at visit 1 and six at visit 2. Conclusions: Our intervention showed a positive effect on patient knowledge about their treatment. However, our results did not show any improvement in overall medication adherence, which was likely to be because of the initially high level of adherence in our study population. Nevertheless, the intervention appears to have improved adherence in non-adherent patients with low knowledge scores.



Author(s):  
Francisco Pradas ◽  
Alejandro García-Giménez ◽  
Víctor Toro-Román ◽  
Nicolae Ochiana ◽  
Carlos Castellar

Research on the acute physiological response to a padel match is limited. The present study aimed to: (a) evaluate neuromuscular, urinary, and hematological responses after simulated padel competition (SC) and (b) analyze possible gender differences. In this study, 28 high-level padel players participated (men = 13, age = 26.83 ± 6.57 years; women = 15, age = 30.07 ± 4.36 years). The following parameters were analyzed before and after SC: neuromuscular (hand grip strength, squat jump (SJ), countermovement jump (CMJ), and Abalakov jump (ABK)), hematological (red blood cells, hemoglobin, and hematocrit), and urinary (pH, specific gravity, microalbuminuria, and red blood cells). Significant gender differences were found in neuromuscular and hematological responses, with men obtaining higher values (p < 0.05). For the SC influence, changes were noted in ABK and microalbuminuria (p < 0.05). The percentages of change in hand grip strength, SJ (height and watts), CMJ (height), and ABK (height) were higher for men than women (p < 0.05). SC negatively influenced the neuromuscular parameters to a greater extent in women. Our results could be related to gender differences in game actions, the temporal structure, and anthropometric and physiological characteristics. Game dynamics and a different organic response between male and female padel playing were confirmed.



Sensors ◽  
2021 ◽  
Vol 21 (12) ◽  
pp. 3956
Author(s):  
Youngsun Kong ◽  
Hugo F. Posada-Quintero ◽  
Ki H. Chon

The subjectiveness of pain can lead to inaccurate prescribing of pain medication, which can exacerbate drug addiction and overdose. Given that pain is often experienced in patients’ homes, there is an urgent need for ambulatory devices that can quantify pain in real-time. We implemented three time- and frequency-domain electrodermal activity (EDA) indices in our smartphone application that collects EDA signals using a wrist-worn device. We then evaluated our computational algorithms using thermal grill data from ten subjects. The thermal grill delivered a level of pain that was calibrated for each subject to be 8 out of 10 on a visual analog scale (VAS). Furthermore, we simulated the real-time processing of the smartphone application using a dataset pre-collected from another group of fifteen subjects who underwent pain stimulation using electrical pulses, which elicited a VAS pain score level 7 out of 10. All EDA features showed significant difference between painless and pain segments, termed for the 5-s segments before and after each pain stimulus. Random forest showed the highest accuracy in detecting pain, 81.5%, with 78.9% sensitivity and 84.2% specificity with leave-one-subject-out cross-validation approach. Our results show the potential of a smartphone application to provide near real-time objective pain detection.



2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Trevor Lee-Miller ◽  
Marco Santello ◽  
Andrew M. Gordon

AbstractSuccessful object manipulation, such as preventing object roll, relies on the modulation of forces and centers of pressure (point of application of digits on each grasp surface) prior to lift onset to generate a compensatory torque. Whether or not generalization of learned manipulation can occur after adding or removing effectors is not known. We examined this by recruiting participants to perform lifts in unimanual and bimanual grasps and analyzed results before and after transfer. Our results show partial generalization of learned manipulation occurred when switching from a (1) unimanual to bimanual grasp regardless of object center of mass, and (2) bimanual to unimanual grasp when the center of mass was on the thumb side. Partial generalization was driven by the modulation of effectors’ center of pressure, in the appropriate direction but of insufficient magnitude, while load forces did not contribute to torque generation after transfer. In addition, we show that the combination of effector forces and centers of pressure in the generation of compensatory torque differ between unimanual and bimanual grasping. These findings highlight that (1) high-level representations of learned manipulation enable only partial learning transfer when adding or removing effectors, and (2) such partial generalization is mainly driven by modulation of effectors’ center of pressure.



2014 ◽  
Vol 519-520 ◽  
pp. 636-639
Author(s):  
Bao Long Zhang ◽  
Shao Jing Zhang ◽  
Wei Qi Ding ◽  
Hui Shuang Shi

The fisheye lens is a kind of ultra wide angle lens, which can produce a big super-wide-angle lens distortion. In order to cover a large scope of light, barrel distortion is artificially added to the optical system. However, in some cases this distortion is not allowed, then it requires calibrations of those distortions. Most of the traditional distortion calibration method uses target plane calibration to do it. This paper discusses the way of design fisheye lens, through which we can know the forming process of distortion clearly. Based on this paper, a simple and effective calibration method can be understood. Different from common camera calibration method, the proposed calibration method can avoid the error occurring in the process of calibrating test, that directly use the lens’ characteristic curve. Through multiple sets of experimental verifications, this method is effective and feasible.



2006 ◽  
Author(s):  
Mang Ou-Yang ◽  
Yung-Lin Chen ◽  
Hsin-Hung Lee ◽  
Shih-chieh LU ◽  
Hsien-Ming Wu


1972 ◽  
Vol 20 (2) ◽  
pp. 239-252 ◽  
Author(s):  
J. M. Robertson ◽  
E. C. R. Reeve

SUMMARYThe resistance levels conferred by the T-determinants in four R-factors to Tetracycline and Minocycline in cells ofEscherichia coliK 12, before and after induction of maximum resistance by treatment with sub-inhibitory concentrations of the drugs, are measured by simple growth-and-challenge tests. The effect of a plasmid TKwhich confers tetracycline resistance on its hostKlebsiella aerogenesis tested in the same way. The five T-determinants fall into a high-level and a low-level group for resistance, the former giving 3- to 4-fold higher resistance in both induced and uninduced cells than the latter. The T-determinants all confer much lower resistance to Minocycline (a tetracycline molecule modified at the C-6 and C-7 positions) than to Tetracycline. The main cause of this difference is that cells carrying a T-determinant exclude Minocycline much less efficiently than Tetracycline, but in addition Minocycline is less effective than Tetracycline in inducing increased resistance. These results are discussed in the light of a model put forward to explain the inducible nature of R-factor resistance to the tetracyclines.



2018 ◽  
Vol 46 (2) ◽  
pp. 177-184
Author(s):  
Sumon Debnath ◽  
Gulshan Ara Latifa ◽  
Mohajira Begum ◽  
Md Abu Obaida

Present study was conducted to evaluate nutritional values of smoked hilsa fish (Tenualosa ilisha; Hamilton, 1882) in relation to its raw condition. Smoking is one of the processes of fish preservation from ancient period of our country. The nutrients values of the hilsa from two different regions were significantly (p < 0.05) varied. The nutritional values were different before and after processing of hilsa. Riverine hilsa contains relatively more moisture (56.45 ± 0.51%) and protein (15.98 ± 0.50%) than marine hilsa. Fat (16.18 ± 0.45%) and salt (1.92 ± 0.18%) contents are higher in marine hilsa; whereas ash (8.34 ± 0.35%) content was higher in riverine hilsa. Minerals like iron (4.72 ± 0.08 mg/100 g) and calcium (481.77 ± 6.20 mg/100g) remain in large amount on marine hilsa but phosphorus (115.73 ± 4.36 mg/100 g) content remain high level in riverine hilsa. In addition, the protein (raw condition, 19.54 ± 0.47%, riverine; 17.12 ± 0.42%, marine and smoked condition, 29.64 ± 0.41%, riverine; 28.51 ± 0.51%, marine) and fat (raw condition, 16.41 ± 0.46%, riverine; 20.07 ± 0.39%, marine and smoked condition, 20.71 ± 0.47%, riverine; 23.31 ± 0.47%, marine) content were higher in abdominal region of riverine and marine hilsa both raw and smoked condition than head region (protein in raw condition, 11.21 ± 0.51%, riverine; 10.51 ± 0.53%, marine and smoked condition, 17.14 ± 0.42%, riverine; 15.69 ± 0.4%, marine; fat in raw condition, 9.04 ± 0.45%, riverine; 11.21 ± 0.51%, marine and smoked condition, 12.32 ± 0.44%, riverine; 14.56 ± 0.47%, marine) and caudal region (protein in raw condition17.21 ± 0.52%, riverine; 15.22 ± 0.66%, marine and smoked condition, 27.68 ± 0.44%, riverine; 26.73 ± 0.46%, marine; fat in raw condition, 14.05 ± 0.5%, riverine; 17.28 ± 0.47%, marine and smoked condition, 17.35 ± 0.43%, riverine; 19.18 ± 0.51%, marine). Bangladesh J. Zool. 46(2): 177-184, 2018



2000 ◽  
Vol 279 (1) ◽  
pp. G157-G162 ◽  
Author(s):  
Esther Staunton ◽  
Scott D. Smid ◽  
John Dent ◽  
L. Ashley Blackshaw

Activation of gastric vagal mechanoreceptors by distention is thought to be the trigger for transient lower esophageal sphincter relaxations (TLESR), which lead to gastroesophageal reflux. The contribution of higher-threshold gastric splanchnic mechanoreceptors is uninvestigated. GABABreceptor agonists, including baclofen, potently reduce triggering of TLESR by low-level gastric distention. We aimed to determine first whether this effect of baclofen is maintained at high-level distention and second the role of splanchnic pathways in triggering TLESR. Micromanometric/pH studies in conscious ferrets showed that intragastric glucose infusion (25 ml) increased triggering of TLESR and reflux. Both were significantly reduced by baclofen (7 μmol/kg ip) ( P < 0.05). When 40 ml of air was added to the glucose infusion, more TLESR occurred than with glucose alone ( P < 0.01). These were also reduced by baclofen ( P < 0.001). TLESR after glucose/air infusion were assessed before and after splanchnectomy (2–4, 9–11, and 23–25 days), which revealed no change. Baclofen inhibits TLESR after both low- and high-level gastric distention. Splanchnic pathways do not contribute to increased triggering of TLESR by high-level gastric distention.



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