scholarly journals Experiences of Preoperative COVID-19 Screening in Pediatric Patients in a Secondary Care Center

2021 ◽  
Vol 27 (1) ◽  
pp. 1
Author(s):  
Kwang-Jin Lee ◽  
Suk Bae Moon ◽  
Sang-Ji Choi ◽  
Gibong Chae ◽  
Sung-Bae Park ◽  
...  
Keyword(s):  
Secondary Care ◽  
Pediatric Patients ◽  
Care Center

Relationship between Clinical and Biologic Variables and Chloramphenicol Pharmacokinetic Parameters in Pediatric Patients with Sepsis

2000 ◽  
Vol 34 (3) ◽  
pp. 393-397 ◽  
Author(s):  
Gustavo Lugo Goytia ◽  
Ismael Lares-Asseff ◽  
María Gabriela Pérez Guillé ◽  
Adrián Guillé Pérez ◽  
Cynthia Larios Mejía
Keyword(s):  
Population Model ◽  
Pediatric Patients ◽  
Care Center ◽  
Tertiary Care ◽  
Pharmacokinetic Parameters ◽  
Pharmacokinetic Data ◽  
Study Group ◽  
Validation Group ◽  
Wbc Count ◽  
Biologic Factors

OBJECTIVE: To evaluate the influence of several clinical and biologic factors on the disposition kinetics of oral chloramphenicol in pediatric patients and to determine the usefulness of this information to predict chloramphenicol serum concentrations. STUDY DESIGN: The clinical, biologic, and pharmacokinetic data of 30 consecutive pediatric patients diagnosed with sepsis and admitted to a tertiary care center were analyzed retrospectively. The patients were randomly assigned to a study group and a validation group. The model was developed by a three-step approach involving Bayesian estimation of pharmacokinetic parameters, selection of covariates by principal component analysis, and final selection by stepwise multiple linear regression. The model was tested in the study group and compared with a general population model using a prediction error analysis. RESULTS: Regression analysis revealed that weight, albumin, and white blood cell (WBC) count were the most important determinants for chloramphenicol distribution volume, whereas age, WBC count, and serum creatinine were the most important determinants for chloramphenicol clearance. The performance of the constructed population model improved significantly in terms of both bias and precision compared with the general model when tested in the validation group. CONCLUSIONS: Clinical and biologic factors may significantly influence chloramphenicol's disposition in pediatric patients with sepsis and therefore should be considered in programming dosage regimens.

scholarly journals CHARACTERISTICS AND LONGER-TERM OUTCOMES OF PEDIATRIC PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY: A TERTIARY CARE CENTER EXPERIENCE

2019 ◽  
Vol 73 (9) ◽  
pp. 878
Author(s):  
Alaa Alashi ◽  
Laurence Svensson ◽  
Jared Klein ◽  
Kenneth Zahka ◽  
Nicholas Smedira ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Pediatric Patients ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center

scholarly journals Penetrating stab wounds to abdomen: Results of our secondary care center

2020 ◽  
Vol 34 (2) ◽  
pp. 62-68
Author(s):  
Fevzi Kurt ◽  
Sevdiye Acele ◽  
Cem Sezer
Keyword(s):  
Secondary Care ◽  
Care Center ◽  
Stab Wounds

scholarly journals COVID-19 in-hospital mortality of a secondary care center of Mexico City in a marginated area during the first months of the Mexican epidemic

2021 ◽  
Author(s):  
José Martín Alanís-Naranjo ◽  
Víctor Manuel Anguiano-Álvarez ◽  
Eduardo Federico Hammeken-Larrondo
Keyword(s):  
Intensive Care ◽  
Hospital Mortality ◽  
Mexico City ◽  
Secondary Care ◽  
Care Center ◽  
Severe Pneumonia ◽  
P Value ◽  
Intravenous Antibiotics ◽  
Tertiary Hospitals ◽  
Hospital Acquired

Abstract Introduction: Low socioeconomic conditions and hospital saturation have been associated with higher mortality rates in hospitalized patients with COVID-19. Mexico City has become the country’s highest death toll. Iztapalapa is the district with the highest population density and marginalization in Mexico City. Most of the information on COVID-19 in-hospital mortality in Mexico comes from intensive care units or tertiary hospitals without considering the level of income. Data regarding hospital mortality in care centers with low availability of intensive care beds has not been explored.Material and methods: A retrospective cohort study in consecutive patients with COVID-19 hospitalized managed outside the intensive care unit in a secondary care center in Mexico City from April 1st, 2020, to May 31st, 2020. Analysis was performed between subgroups with a p-value <0.05 considered statistically significant.Results: A total of 164 patients were recruited; the median age was 52.5 years (IQR 44 - 64.5), 68% were males, 48.7% were obese, and 59.7% had comorbidities. Among those patients, 67% required mechanical ventilation and 32.3% vasopressor support. In this population, 52 recovered (31.7%) and 112 died (68.3%). The main risk factors associated with death were male sex, age > 50 years, diabetes, severe pneumonia on admission, PORT / PSI > 91, SMART-COP > 5, SCAP score > 10, dyspnea on admission, fever during hospitalization [p <0.05] and the administration of intravenous antibiotics [RR 3.45, 95% CI 1.69-7.06, p <0.001].Conclusion: In this study, we found higher in-hospital mortality compared to previous reports. We suggest that the administration of intravenous antibiotics could impact patient survival for the risk of developing hospital-acquired infections.

scholarly journals Clinical Spectrum of COVID-19 in a Pediatric Mexican Population

2020 ◽  
Author(s):  
Edgar Bustos-Cordova ◽  
Daniela Castillo-García ◽  
Magdalena Cerón-Rodriguez ◽  
Nadia Soler-Quiñones
Keyword(s):  
Emergency Department ◽  
Pediatric Patients ◽  
Care Center ◽  
Tertiary Care ◽  
Signs And Symptoms ◽  
Clinical Spectrum ◽  
Tertiary Care Center ◽  
Rt Pcr ◽  
Excessive Crying ◽  
Pcr Test

Abstract ObjectiveFrom the beginning of the COVID-19 pandemic, it has become evident that the spectrum of manifestations in children is different from those seen in adults. In this study, we aimed to describe a broader clinical spectrum of COVID-19 in children.MethodsIn this descriptive, prospective study, we included confirmed pediatric patients with COVID-19 who presented to the emergency department of a pediatric tertiary care center from April to July 2020. All patients were confirmed by the SARS-CoV-2 RT-PCR test, and we analyzed 24 symptoms and 25 signs.ResultsWe analyzed 50 patients with COVID-19. From the evaluated signs and symptoms, the most common symptoms were fever, excessive crying and dry cough, digestive symptoms were frequently found (24%), and the most common signs were pharyngeal erythema and irritability.ConclusionClinicians should recognize that the clinical spectrum of COVID-19 in children is wider than previously described, often with nonspecific signs and symptoms, and digestive symptoms should raise suspicion.

scholarly journals Prognostic Factors in Patients with COVID-19 Disease: A Retrospective Study in a Secondary Care Center

2021 ◽  
Vol 10 (3) ◽  
pp. 84
Author(s):  
Clemens Stiegler ◽  
Tanja Seel ◽  
Claus Schaefer
Keyword(s):  
Prognostic Factors ◽  
Retrospective Study ◽  
Secondary Care ◽  
Care Center

scholarly journals Perioperative hypothermia in pediatric patients operated in a tertiary care center: Incidence and correlates

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Osman ESEN ◽  
Gülseren YILMAZ ◽  
Nevin AYDIN
Keyword(s):  
Body Temperature ◽  
Surgical Procedures ◽  
Pediatric Patients ◽  
Care Center ◽  
Tertiary Care ◽  
Fluid Replacement ◽  
Prospective Clinical Study ◽  
Tertiary Care Center ◽  
Body Temperatures ◽  
Perioperative Hypothermia

Background & Objectives: Hypothermia, described as temperature < 35°C, is a frequent condition encountered in patients operated under general anesthesia. It is associated with significant morbidity and mortality. We aimed to estimate its incidence and to investigate the conditions associated with hypothermia in pediatric patients. Methods: This prospective clinical study was carried out in the operating theatre of a tertiary care center between August 2015 and September 2015. A total of 108 pediatric patients who underwent various surgical procedures that lasted for more than 30 minutes were enrolled. Baseline demographic data, types of surgical procedures, duration of operations, preoperative and perioperative body temperatures were recorded. The incidence of hypothermia and its possible correlates were sought. Results: Our series consisted of 108 children (77 males, 71.3%; 31 females, 28.7%) with an average age of 6.08±5.09 years were included in the study. There was no case diagnosed with hypothermia in the preoperative, perioperative and postoperative periods. Patients in American Society of Anesthesiologists classification (ASA) three group had significantly higher preoperative body temperatures compared to those in ASA-1 and ASA-2 groups (p = 0.027). The postoperative body temperature in patients receiving intravenous fluid replacement was significantly lower (p=0.017). Conclusion: For pediatric patients scheduled for surgical interventions, we recommend close monitorization and follow-up of body temperature, implementation of preventive measures to avoid hypothermia and routine perioperative heating. Avoidance of hypothermia may prevent hazardous consequences of postoperative hypothermia. doi: https://doi.org/10.12669/pjms.36.4.456 How to cite this:Esen O, Yilmaz G, Aydin N. Perioperative hypothermia in pediatric patients operated in a tertiary care center: Incidence and correlates. Pak J Med Sci. 2020;36(4):---------. doi: https://doi.org/10.12669/pjms.36.4.456 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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